| LH/Mav |
systolic blood pressure |
perindopril (1.5 mg/kg/d) (for 42 days) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
arterial blood pressure trait |
male |
63.0 days
| 7 |
undefined |
113.0 |
mmHg |
3.0 |
7.94 |
tail cuff plethysmography |
0.0 |
|
102850 |
2761 |
| LH/Mav |
body weight |
perindopril (0.4 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
161.0 days
| 8 |
|
459.0 |
g |
10.0 |
28.28 |
body weighing method |
0.0 |
|
102804 |
2723 |
| LH/Mav |
body weight |
perindopril (0.04 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
161.0 days
| 6 |
|
457.0 |
g |
11.0 |
26.94 |
body weighing method |
0.0 |
|
102807 |
2723 |
| LH/Mav |
plasma triglyceride level |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood triglyceride amount |
male |
112.0 days
| 10 |
|
2.42 |
mmol/l |
0.3 |
0.95 |
plasma triglyceride analysis |
0.0 |
|
102671 |
2703 |
| LH/Mav |
plasma triglyceride level |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood triglyceride amount |
male |
112.0 days
| 11 |
|
1.5 |
mmol/l |
0.12 |
0.4 |
plasma triglyceride analysis |
0.0 |
|
102672 |
2703 |
| LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112.0 days
| 11 |
|
10.1 |
mg/100g |
0.2 |
0.66 |
post excision weight measurement |
0.0 |
|
102690 |
2703 |
| LH/Mav |
body weight |
perindopril (0.4 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
112.0 days
| 8 |
|
405.0 |
g |
7.0 |
19.8 |
body weighing method |
0.0 |
|
102790 |
2723 |
| LH/Mav |
body weight |
perindopril (0.04 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
112.0 days
| 6 |
|
372.0 |
g |
9.0 |
22.05 |
body weighing method |
0.0 |
|
102793 |
2723 |
| LH/Mav |
renal blood flow rate to kidney weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
renal blood flow trait |
male |
84.0 days
| 7 |
|
5.3 |
ml/min/g |
0.5 |
1.32 |
ultrasonic flowmeter |
0.0 |
|
102854 |
2761 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
heart left ventricle mass |
male |
119.0 days
| 8 |
|
2.41 |
mg/g |
0.08 |
0.23 |
post excision weight measurement |
0.0 |
|
103410 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
aorta mass |
male |
119.0 days
| 8 |
|
12.5 |
mg/100g |
0.6 |
1.7 |
post excision weight measurement |
0.0 |
|
103415 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
aorta mass |
male |
119.0 days
| 8 |
|
13.6 |
mg/100g |
0.5 |
1.41 |
post excision weight measurement |
0.0 |
|
103416 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
|
6.22 |
g/kg |
0.21 |
0.59 |
post excision weight measurement |
0.0 |
|
103420 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
|
5.87 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
|
103421 |
2824 |
| LH/Mav |
plasma total cholesterol level |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood cholesterol amount |
male |
112.0 days
| 10 |
|
83.78 |
mg/dl |
6.56 |
20.76 |
blood cholesterol analysis |
0.0 |
|
102665 |
2703 |
| LH/Mav |
plasma creatinine level |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood creatinine amount |
male |
112.0 days
| 11 |
|
0.54 |
mg/dl |
0.01 |
0.03 |
plasma creatinine analysis |
0.0 |
|
102678 |
2703 |
| LH/Mav |
plasma creatinine level |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood creatinine amount |
male |
112.0 days
| 9 |
|
0.54 |
mg/dl |
0.01 |
0.03 |
plasma creatinine analysis |
0.0 |
|
102677 |
2703 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112.0 days
| 11 |
|
19.9 |
mg/g |
0.5 |
1.66 |
post excision weight measurement |
0.0 |
|
102684 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 9 |
|
7.02 |
g/kg |
0.18 |
0.54 |
post excision weight measurement |
0.0 |
|
102695 |
2703 |
| LH/Mav |
body weight |
perindopril (0.04 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
112.0 days
| 8 |
|
394.0 |
g |
4.0 |
11.31 |
body weighing method |
0.0 |
|
102788 |
2723 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
heart left ventricle mass |
male |
119.0 days
| 8 |
|
2.37 |
mg/g |
0.07 |
0.2 |
post excision weight measurement |
0.0 |
|
103411 |
2824 |
| LH/Mav |
body weight |
perindopril (0.1 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
112.0 days
| 8 |
|
404.0 |
g |
6.0 |
16.97 |
body weighing method |
0.0 |
|
102789 |
2723 |
| LH/Mav |
renal vascular resistance to kidney weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
kidney blood vessel physiology trait |
male |
84.0 days
| 7 |
SBP/RBF |
23.0 |
ml/min/g/mmHg |
2.0 |
5.29 |
ultrasonic flowmeter |
0.0 |
|
102858 |
2761 |
| LH/Mav |
body weight |
perindopril (0.04 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
161.0 days
| 8 |
|
442.0 |
g |
6.0 |
16.97 |
body weighing method |
0.0 |
|
102802 |
2723 |
| LH/Mav |
body weight |
perindopril (0.1 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
161.0 days
| 8 |
|
452.0 |
g |
5.0 |
14.14 |
body weighing method |
0.0 |
|
102803 |
2723 |
| LH/Mav |
body weight |
perindopril (0.01 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
161.0 days
| 6 |
|
460.0 |
g |
14.0 |
34.29 |
body weighing method |
0.0 |
|
102806 |
2723 |
| LH/Mav |
plasma total cholesterol level |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
blood cholesterol amount |
male |
112.0 days
| 11 |
|
73.36 |
mg/dl |
4.63 |
15.37 |
blood cholesterol analysis |
0.0 |
|
102666 |
2703 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112.0 days
| 9 |
|
23.8 |
mg/g |
0.8 |
2.4 |
post excision weight measurement |
0.0 |
|
102683 |
2703 |
| LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112.0 days
| 9 |
|
12.3 |
mg/100g |
0.4 |
1.2 |
post excision weight measurement |
0.0 |
|
102689 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 11 |
|
6.44 |
g/kg |
0.14 |
0.46 |
post excision weight measurement |
0.0 |
|
102696 |
2703 |
| LH/Mav |
body weight |
perindopril (0.01 mg/kg/d) (for 98 days) |
Egan EJ, et al., Acta Pharmacol Sin. 2008 Nov;29(11):1296-300. doi: 10.1111/j.1745-7254.2008.00862.x. |
body mass |
male |
112.0 days
| 6 |
|
391.0 |
g |
8.0 |
19.6 |
body weighing method |
0.0 |
|
102792 |
2723 |