Phenominer Database Results (15 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Record ID Study ID
LH/Mav renal blood flow rate to kidney weight ratio hydralazine (75 mg/kg/d) (for 63 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. renal blood flow trait male 84.0 days 10 4.7 ml/min/g 0.3 0.95 ultrasonic flowmeter 0.0 102856 2761
LH/Mav both kidneys wet weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119.0 days 6 7.22 g/kg 0.34 0.83 post excision weight measurement 0.0 103422 2824
LH/Mav plasma total cholesterol level streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood cholesterol amount male 112.0 days 7 110.81 mg/dl 4.25 11.24 blood cholesterol analysis 0.0 102667 2703
LH/Mav plasma triglyceride level streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood triglyceride amount male 112.0 days 7 1.58 mmol/l 0.08 0.21 plasma triglyceride analysis 0.0 102673 2703
LH/Mav aorta weight to body weight ratio streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. aorta mass male 112.0 days 7 12.5 mg/100g 0.5 1.32 post excision weight measurement 0.0 102691 2703
LH/Mav both kidneys wet weight to body weight ratio streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. kidney mass male 112.0 days 7 8.05 g/kg 0.24 0.63 post excision weight measurement 0.0 102697 2703
LH/Mav heart left ventricle weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. heart left ventricle mass male 119.0 days 6 2.88 mg/g 0.06 0.15 post excision weight measurement 0.0 103412 2824
LH/Mav both kidneys wet weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. kidney mass male 119.0 days 7 7.3 g/kg 0.09 0.24 post excision weight measurement 0.0 103423 2824
LH/Mav heart left ventricle weight to body weight ratio streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. heart left ventricle mass male 112.0 days 7 24.2 mg/g 0.3 0.79 post excision weight measurement 0.0 102685 2703
LH/Mav systolic blood pressure hydralazine (75 mg/kg/d) (for 42 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 42 days) and reserpine (0.75 mg/kg/d) (for 42 days) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. arterial blood pressure trait male 63.0 days 10 undefined 133.0 mmHg 2.0 6.32 tail cuff plethysmography 0.0 102852 2761
LH/Mav heart left ventricle weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. heart left ventricle mass male 119.0 days 7 2.79 mg/g 0.04 0.11 post excision weight measurement 0.0 103413 2824
LH/Mav aorta weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. aorta mass male 119.0 days 6 15.7 mg/100g 0.8 1.96 post excision weight measurement 0.0 103417 2824
LH/Mav plasma creatinine level streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. blood creatinine amount male 112.0 days 7 0.59 mg/dl 0.02 0.04 plasma creatinine analysis 0.0 102679 2703
LH/Mav renal vascular resistance to kidney weight ratio hydralazine (75 mg/kg/d) (for 63 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. kidney blood vessel physiology trait male 84.0 days 10 SBP/RBF 27.0 ml/min/g/mmHg 2.0 6.32 ultrasonic flowmeter 0.0 102869 2761
LH/Mav aorta weight to body weight ratio controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. aorta mass male 119.0 days 7 15.8 mg/100g 0.8 2.12 post excision weight measurement 0.0 103418 2824