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| Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Duration |
Post Insult Time Value |
Record ID |
Study ID |
| Hsd:WI |
timed urine volume |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
urine output |
male |
days
| 6 |
9.2 |
ml/d |
0.69 |
1.7 |
urine volume measurement method |
0.0 |
|
75968 |
1544 |
| Hsd:WI |
kidney glutathione level |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney glutathione amount |
male |
days
| 6 |
9864.97 |
ug/g |
200.74 |
491.71 |
liquid phase colorimetry |
0.0 |
|
76241 |
1544 |
| Hsd:WI |
kidney catalase activity to total protein level ratio |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
catalase activity |
male |
days
| 6 |
30.56 |
nmol/mg |
0.37 |
0.9 |
liquid phase colorimetry |
0.0 |
|
76237 |
1544 |
| Hsd:WI |
serum creatinine level |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
blood creatinine amount |
male |
days
| 6 |
0.85 |
mg/dl |
0.03 |
0.08 |
serum creatinine analysis |
0.0 |
|
75975 |
1544 |
| Hsd:WI |
both kidneys wet weight |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney mass |
male |
days
| 6 |
0.84 |
g |
0.03 |
0.08 |
post excision weight measurement |
0.0 |
|
75959 |
1544 |
| Hsd:WI |
kidney lipid peroxide level |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney lipid peroxide amount |
male |
days
| 6 |
0.88 |
nmol/mg |
0.02 |
0.06 |
liquid phase colorimetry |
0.0 |
|
76259 |
1544 |
| Hsd:WI |
kidney superoxide dismutase activity to total protein level ratio |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney superoxide dismutase activity |
male |
days
| 6 |
11.74 |
U/mg |
0.56 |
1.38 |
liquid phase colorimetry |
0.0 |
|
76190 |
1544 |
| Hsd:WI |
body weight |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
body mass |
male |
days
| 6 |
143.6 |
g |
0.41 |
1.0 |
body weighing method |
0.0 |
|
75954 |
1544 |
| Hsd:WI |
kidney glutathione peroxidase activity to total protein level ratio |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
kidney glutathione peroxidase activity |
male |
days
| 6 |
15.4 |
U/mg |
0.29 |
0.71 |
liquid phase colorimetry |
0.0 |
|
76194 |
1544 |
| Hsd:WI |
serum urea nitrogen level |
silymarin (50 mg/kg/d) (for 10 days) then cisplatin (7.5 mg/kg) |
Prabhu VV, et al., Pharmacol Rep. 2013;65(4):980-90. |
blood urea nitrogen amount |
male |
days
| 6 |
75.2 |
mg/dl |
2.16 |
5.3 |
liquid phase colorimetry |
0.0 |
|
75979 |
1544 |
|