| FHH/EurMcwi |
urine total protein excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
total urine protein amount |
female |
80.0 days-99.0 days |
16 |
170.33 |
mg/d |
49.67 |
198.67 |
automated urine total protein analysis |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52097 |
482 |
| FHH/EurMcwi |
urine total protein excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
total urine protein amount |
male |
80.0 days-99.0 days |
48 |
472.36 |
mg/d |
30.23 |
209.46 |
automated urine total protein analysis |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52115 |
482 |
| FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
blood creatinine amount |
female |
80.0 days-99.0 days |
12 |
0.4 |
mg/dl |
0.03 |
0.12 |
radioimmunoassay |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52246 |
482 |
| FHH/EurMcwi |
urine sodium excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine sodium amount |
female |
80.0 days-99.0 days |
16 |
14.02 |
mEq/d |
1.77 |
7.07 |
flame atomic emission spectrometry |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52783 |
482 |
| FHH/EurMcwi |
urine sodium excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine sodium amount |
male |
80.0 days-99.0 days |
48 |
18.43 |
mEq/d |
0.86 |
5.95 |
flame atomic emission spectrometry |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52801 |
482 |
| FHH/EurMcwi |
urine potassium excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine potassium amount |
female |
80.0 days-99.0 days |
16 |
0.92 |
mEq/d |
0.05 |
0.2 |
flame atomic emission spectrometry |
|
|
urine potassium analysis |
Moms were fed Teklad, pups used in studies were fed Dyets |
52295 |
482 |
| FHH/EurMcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
female |
80.0 days-99.0 days |
16 |
63.36 |
mg/d |
21.06 |
84.26 |
radioimmunoassay |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52389 |
482 |
| FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
female |
80.0 days-99.0 days |
14 |
6.0 |
ng/ml/h |
0.7 |
2.62 |
radioimmunoassay |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52881 |
482 |
| FHH/EurMcwi |
urine potassium excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine potassium amount |
male |
80.0 days-99.0 days |
48 |
1.26 |
mEq/d |
0.05 |
0.38 |
flame atomic emission spectrometry |
|
|
urine potassium analysis |
Moms were fed Teklad, pups used in studies were fed Dyets |
52313 |
482 |
| FHH/EurMcwi |
urine albumin excretion rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
urine albumin amount |
male |
80.0 days-99.0 days |
48 |
183.29 |
mg/d |
13.89 |
96.23 |
radioimmunoassay |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52407 |
482 |
| FHH/EurMcwi |
heart rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
heart pumping trait |
female |
80.0 days-99.0 days |
15 |
429.33 |
beats/min |
8.27 |
32.03 |
vascular fluid filled catheter |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52487 |
482 |
| FHH/EurMcwi |
plasma renin activity level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
renin activity |
male |
80.0 days-99.0 days |
38 |
2.57 |
ng/ml/h |
0.36 |
2.21 |
radioimmunoassay |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52899 |
482 |
| FHH/EurMcwi |
plasma creatinine level |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
blood creatinine amount |
male |
80.0 days-99.0 days |
39 |
0.43 |
mg/dl |
0.02 |
0.1 |
radioimmunoassay |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52264 |
482 |
| FHH/EurMcwi |
creatinine clearance |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
glomerular filtration trait |
female |
80.0 days-99.0 days |
12 |
1.47 |
ml/min |
0.25 |
0.85 |
urine creatinine analysis |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52342 |
482 |
| FHH/EurMcwi |
mean arterial blood pressure |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
arterial blood pressure trait |
male |
80.0 days-99.0 days |
48 |
181.54 |
mmHg |
2.9 |
20.07 |
vascular fluid filled catheter |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52552 |
482 |
| FHH/EurMcwi |
creatinine clearance |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
glomerular filtration trait |
male |
80.0 days-99.0 days |
39 |
1.44 |
ml/min |
0.09 |
0.57 |
urine creatinine analysis |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52360 |
482 |
| FHH/EurMcwi |
heart rate |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
heart pumping trait |
male |
80.0 days-99.0 days |
48 |
431.04 |
beats/min |
4.26 |
29.51 |
vascular fluid filled catheter |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52505 |
482 |
| FHH/EurMcwi |
mean arterial blood pressure |
controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) |
PhysGen Renal B data |
arterial blood pressure trait |
female |
80.0 days-99.0 days |
15 |
165.97 |
mmHg |
7.47 |
28.91 |
vascular fluid filled catheter |
|
|
|
Moms were fed Teklad, pups used in studies were fed Dyets |
52534 |
482 |