Phenominer Database Results (140 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 8 5.66 mmHg 0.2 0.56 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49221 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 6.03 mmHg 0.16 0.48 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49226 461
GH/OmrMcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 10 875.15 s 114.44 361.88 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49343 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 7 0.27 IU/g 0.04 0.11 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 49678 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 9 0.32 IU/g 0.04 0.13 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 49682 461
GH/OmrMcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 7 52.86 mmHg 4.36 11.54 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 49795 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 10 14.49 IU/g 1.35 4.27 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 49834 461
GH/OmrMcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 10 713.4 s 84.0 265.63 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50168 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 209.85 beats/min 7.0 19.8 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47626 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 10 93.64 mmHg 12.1 38.28 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48498 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 66.02 % 2.67 7.05 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48502 461
GH/OmrMcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 11 63.0 mmHg 3.36 11.15 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48722 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 79.44 mmHg 11.13 33.4 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45692 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 10 9.43 IU/g 1.35 4.27 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 45699 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 5 144.94 mmHg 7.52 16.81 balloon tipped catheter with pressure transducer in isolated perfused heart 46799 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 332.88 beats/min 25.85 85.72 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47685 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 10 58.37 mmHg 5.1 16.14 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47750 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 134.95 mmHg 8.68 26.03 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45820 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 10 146.42 mmHg 5.9 18.65 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45825 461
GH/OmrMcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 75.14 % 3.84 11.51 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46038 461
GH/OmrMcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 9 694.02 s 73.57 220.72 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45122 461
GH/OmrMcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 11 721.53 s 49.05 162.68 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45127 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 11 9.72 ml/min/g 0.43 1.43 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46303 461
GH/OmrMcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 post-ischemic value/pre-ischemic value x 100% 77.47 % 6.55 18.52 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48455 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 220.06 beats/min 18.59 58.78 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48989 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 10 22.59 % 5.27 16.68 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 49440 461
GH/OmrMcwi time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 9 665.56 s 71.25 213.76 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50163 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 274.41 beats/min 26.8 80.39 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 50313 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 140.6 mmHg 5.33 14.09 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45548 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 8 8.12 ml/min/g 1.74 4.91 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46523 461
GH/OmrMcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 1047.5 s 72.16 228.2 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46597 461
GH/OmrMcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 54.46 % 9.53 28.58 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 47519 461
GH/OmrMcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 6 post-ischemic value/pre-ischemic value x 100% 56.6 % 5.4 13.24 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 47515 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 5.0 mmHg 0.17 0.5 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47539 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 5 0.26 IU/g 0.06 0.13 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 47561 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 54.64 % 10.4 32.9 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48571 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 214.57 mmHg 18.48 48.9 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48734 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 144.29 mmHg 12.97 34.31 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48726 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 227.67 mmHg 6.56 19.67 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48738 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 3.89 mmHg 0.26 0.78 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48916 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 10 9.98 ml/min/g 2.16 6.83 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 44762 461
GH/OmrMcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 1119.98 s 32.84 98.53 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45878 461
GH/OmrMcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 50.68 % 8.53 28.3 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45922 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 7.98 ml/min/g 0.73 2.2 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46919 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 8 57.23 mmHg 8.21 23.21 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47955 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 10 122.6 mmHg 8.94 28.26 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 44864 461
GH/OmrMcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 72.69 % 8.14 27.01 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46030 461
GH/OmrMcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 53.51 % 7.02 22.2 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46115 461
GH/OmrMcwi percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 53.44 % 5.49 14.52 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47121 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 271.34 beats/min 13.39 42.34 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48241 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 11 140.21 mmHg 2.76 9.14 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45010 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 232.67 mmHg 6.49 19.48 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45379 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 11 4.03 mmHg 0.19 0.62 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48921 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 6 9.38 % 2.95 7.23 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 49630 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 5 7.24 % 0.99 2.22 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 49639 461
GH/OmrMcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 9 48.78 mmHg 6.85 20.55 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 49799 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 135.34 mmHg 10.99 34.74 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 49932 461
GH/OmrMcwi heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 9 42.33 mmHg 5.6 16.81 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50041 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 263.55 beats/min 15.25 48.22 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 50318 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 6 143.98 mmHg 8.56 20.97 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45553 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 33.27 mmHg 6.92 21.88 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46461 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 6 271.62 beats/min 13.53 33.14 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46514 461
GH/OmrMcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 8 56.88 mmHg 7.36 20.82 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48717 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 77.33 % 4.74 14.99 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48800 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 7 11.53 ml/min/g 1.28 3.4 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46697 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 344.41 beats/min 23.76 71.28 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47680 461
GH/OmrMcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 1078.92 s 47.03 155.97 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45883 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 92.12 % 9.64 31.96 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46852 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 62.65 % 7.39 22.16 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46956 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 60.01 % 9.47 31.42 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46961 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 8 122.29 mmHg 7.54 21.33 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 44859 461
GH/OmrMcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 69.1 % 5.05 13.36 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46034 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 57.56 mmHg 6.5 19.49 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45061 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 44.43 mmHg 6.05 16.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45057 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 6 10.33 ml/min/g 0.78 1.91 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46287 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 9 9.84 ml/min/g 0.76 2.29 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46298 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 10 0.37 IU/g 0.07 0.24 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47446 461
GH/OmrMcwi percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 post-ischemic value/pre-ischemic value x 100% 71.22 % 11.09 31.37 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48339 461
GH/OmrMcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 80.79 % 5.17 16.33 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48450 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 189.11 beats/min 10.37 31.11 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45254 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 96.8 mmHg 18.68 59.07 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45314 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 182.8 beats/min 20.76 65.66 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48994 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 9 16.17 % 4.82 14.45 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 49445 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 8 45.39 mmHg 5.12 14.49 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 49613 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 10 6.93 % 2.81 8.88 digital scale post excision weight measurement Moms and pups used in studies were fed Teklad 49742 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 10 18.6 IU/g 3.24 10.24 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 49841 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 5 8.69 IU/g 1.31 2.93 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 50211 461
GH/OmrMcwi time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 1058.67 s 66.16 198.49 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46592 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 4 0.21 IU/g 0.05 0.09 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 47556 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 168.85 mmHg 10.18 32.2 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48668 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 137.0 mmHg 5.88 17.64 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48730 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 174.33 mmHg 10.15 32.11 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45773 461
GH/OmrMcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 9 877.97 s 91.2 273.59 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45841 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 147.59 mmHg 11.01 33.04 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45846 461
GH/OmrMcwi left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 11 144.26 mmHg 2.65 8.8 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45851 461
GH/OmrMcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 71.34 % 12.73 38.19 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45917 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 92.4 % 3.81 11.42 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46847 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 9 8.56 ml/min/g 0.8 2.4 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46914 461
GH/OmrMcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 9 57.67 mmHg 8.32 24.97 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48077 461
GH/OmrMcwi heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 10 56.3 mmHg 5.96 18.86 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48082 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 92.47 % 6.87 18.16 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 44962 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 6 post-ischemic value/pre-ischemic value x 100% 95.09 % 4.96 12.15 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 44967 461
GH/OmrMcwi percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 78.89 % 4.15 12.44 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46025 461
GH/OmrMcwi percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 85.8 % 17.96 53.87 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46110 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 46.9 % 4.98 13.19 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48133 461
GH/OmrMcwi heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 260.48 beats/min 7.71 21.82 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 48246 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 6 5.72 ml/min/g 0.45 1.1 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45096 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 10 6.94 ml/min/g 0.77 2.45 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46245 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 5.86 ml/min/g 0.95 2.85 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 46250 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 48.28 % 7.68 20.31 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46363 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 6 post-ischemic value/pre-ischemic value x 100% 51.84 % 6.01 14.72 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 46368 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 10 0.71 IU/g 0.12 0.39 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47305 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 147.04 beats/min 20.23 63.96 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45192 461
GH/OmrMcwi left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 219.57 mmHg 18.35 48.56 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45375 461
GH/OmrMcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 1126.31 s 65.26 195.77 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48929 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 10 52.84 mmHg 7.8 24.67 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 49618 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 7 9.1 % 3.71 9.82 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 49634 461
GH/OmrMcwi heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 5 7.6 % 1.77 3.97 digital scale post excision weight measurement Moms and pups used in studies were fed Dyets 49644 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 5 13.38 IU/g 5.32 11.9 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 50206 461
GH/OmrMcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 1222.82 s 115.16 364.17 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 50271 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 252.78 beats/min 11.94 35.83 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46518 461
GH/OmrMcwi arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 5.93 ml/min/g 0.33 0.98 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46528 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 5.0 mmHg 0.22 0.58 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 47535 461
GH/OmrMcwi percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 59.35 % 3.41 10.23 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48506 461
GH/OmrMcwi time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 1111.18 s 116.44 308.08 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48925 461
GH/OmrMcwi left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 100.29 mmHg 15.02 39.74 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45688 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 7 134.53 mmHg 6.22 16.47 balloon tipped catheter with pressure transducer in isolated perfused heart 46794 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 8 66.5 mmHg 3.8 10.75 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47745 461
GH/OmrMcwi time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 7 641.83 s 47.92 126.78 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45837 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 10 66.59 mmHg 6.11 19.33 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47960 461
GH/OmrMcwi left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 5.49 mmHg 0.25 0.79 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47241 461
GH/OmrMcwi percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 35.34 % 5.47 16.42 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48137 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 144.9 mmHg 10.99 32.97 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45005 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 5.21 ml/min/g 0.91 2.73 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45100 461
GH/OmrMcwi arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 9.69 ml/min/g 0.71 2.12 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 46291 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 10 1.12 IU/g 0.14 0.46 isolated perfused heart effluent collection Moms and pups used in studies were fed Teklad 47311 461
GH/OmrMcwi left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 92.61 mmHg 13.22 39.67 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 48493 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 176.87 beats/min 23.98 63.44 balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45250 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 6 13.29 IU/g 2.15 5.27 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45367 461
GH/OmrMcwi heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 8 10.99 IU/g 0.94 2.66 isolated perfused heart effluent collection Moms and pups used in studies were fed Dyets 45371 461