Phenominer Database Results (160 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
Hsd:SD percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 58.59 % 29.76 51.55 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49269 461
Hsd:SD heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 3 61.67 mmHg 7.8 13.5 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49596 461
Hsd:SD time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 11 634.93 s 62.43 207.07 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49648 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 84.42 % 22.3 31.54 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49656 461
Hsd:SD time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 905.67 s 30.38 96.07 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49664 461
Hsd:SD time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 13 1034.7 s 53.29 192.14 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49663 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 2 8.4 % 3.6 5.09 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49863 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 3 316.28 beats/min 18.91 32.76 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49979 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 7 22.94 % 3.95 10.46 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50102 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 248.81 beats/min 33.89 89.67 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45587 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 261.19 beats/min 14.7 25.46 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46504 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 11 307.99 beats/min 46.45 154.04 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48508 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 6 333.73 beats/min 31.12 76.22 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48507 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 304.18 beats/min 25.52 76.55 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46632 461
Hsd:SD percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 post-ischemic value/pre-ischemic value x 100% 61.65 % 5.68 17.03 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45712 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 11 114.64 mmHg 7.73 25.63 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 44702 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 11 109.91 mmHg 7.73 25.64 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45885 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 3 8.8 ml/min/g 1.15 1.99 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45894 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 2 7.13 ml/min/g 0.64 0.91 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45898 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 3 68.36 mmHg 3.47 6.01 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45910 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 12 8.79 ml/min/g 0.5 1.72 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46854 461
Hsd:SD percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 73.83 % 5.99 10.38 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47891 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 3 6.54 mmHg 0.24 0.42 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48015 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 98.44 % 5.28 7.47 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46171 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 2 0.31 IU/g 0.04 0.06 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47180 461
Hsd:SD percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 13 post-ischemic value/pre-ischemic value x 100% 50.56 % 3.84 13.85 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48116 461
Hsd:SD percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 49.04 % 6.43 21.32 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48117 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 129.89 mmHg 1.22 1.72 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45023 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 11 12.69 ml/min/g 1.22 4.04 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45053 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 68.96 mmHg 1.89 2.67 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47400 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 12 10.31 IU/g 1.37 4.76 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47416 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 6 52.98 mmHg 7.55 18.49 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47419 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 3 0.04 IU/g 0.01 0.02 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48386 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 260.94 beats/min 12.96 22.44 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45357 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 6 3.98 mmHg 0.35 0.86 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49043 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 114.45 mmHg 11.98 20.75 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49277 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 3 0.33 IU/g 0.14 0.24 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49620 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 7 97.19 mmHg 8.19 21.66 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49623 461
Hsd:SD percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 81.12 % 6.24 19.73 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49626 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 11 75.82 mmHg 11.61 38.5 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49646 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 116.33 mmHg 7.03 21.09 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49650 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 2 140.09 mmHg 12.52 17.7 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49805 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 123.77 mmHg 11.21 15.85 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49809 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 12 17.71 % 3.01 10.42 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50103 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 9 9.75 IU/g 1.75 5.24 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45488 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 11 271.7 beats/min 24.62 81.65 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45588 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 8 63.36 mmHg 7.08 20.02 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46531 461
Hsd:SD percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 55.97 % 5.53 7.82 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47529 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 11 0.24 IU/g 0.04 0.12 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48707 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 7 21.24 % 3.11 8.22 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48740 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 8 119.08 mmHg 9.14 25.86 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47784 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 6 107.06 mmHg 8.61 21.09 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 44701 461
Hsd:SD percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 64.92 % 5.27 7.45 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45861 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 6 103.8 mmHg 8.42 20.62 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45884 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 65.05 mmHg 23.59 40.86 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45906 461
Hsd:SD percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 27.26 % 4.93 15.6 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46963 461
Hsd:SD percent change in arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 81.22 % 6.92 11.99 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47887 461
Hsd:SD time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 10 634.09 s 50.65 160.18 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47895 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 7 35.35 mmHg 4.97 13.14 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46148 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 3 11.22 ml/min/g 1.24 2.14 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46155 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 6.66 mmHg 0.17 0.3 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48161 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 5.2 mmHg 0.29 0.92 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48169 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 301.07 beats/min 20.19 34.97 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48175 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 121.65 mmHg 4.83 8.37 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45019 461
Hsd:SD percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 56.03 % 0.87 1.23 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45049 461
Hsd:SD time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 1082.73 s 172.33 298.49 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45106 461
Hsd:SD time to peak heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 3 1111.09 s 144.75 250.71 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45110 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 75.21 % 11.82 31.26 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46292 461
Hsd:SD heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 3 72.33 mmHg 3.33 5.77 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47384 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 61.36 mmHg 3.02 5.23 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47408 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 11 38.82 mmHg 6.49 21.52 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47420 461
Hsd:SD percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 97.27 % 7.51 24.92 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47418 461
Hsd:SD percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 75.04 % 12.04 31.86 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47417 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 2 0.08 IU/g 0.01 0.01 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45239 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 3 19.87 % 11.92 20.64 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49033 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait female 49.0 days-63.0 days 3 9.47 % 2.98 5.16 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49037 461
Hsd:SD time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 3 508.47 s 198.52 343.85 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49484 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 3 0.31 IU/g 0.07 0.12 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49622 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 86.7 mmHg 7.37 23.3 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49624 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 88.39 % 1.7 2.4 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49660 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 380.39 beats/min 29.41 88.23 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49849 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 349.14 beats/min 30.12 85.19 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49848 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 272.73 beats/min 0.0 0.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46508 461
Hsd:SD percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 7 post-ischemic value/pre-ischemic value x 100% 36.65 % 6.47 17.11 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46529 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 56.3 mmHg 4.75 15.02 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46532 461
Hsd:SD percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 52.78 % 35.43 50.11 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47525 461
Hsd:SD percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 12 post-ischemic value/pre-ischemic value x 100% 80.02 % 6.54 22.66 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45713 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 2 133.65 mmHg 12.39 17.52 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47669 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 117.08 mmHg 11.54 16.32 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47673 461
Hsd:SD percent change in arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 78.01 % 2.23 3.87 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45857 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 3 49.18 mmHg 6.63 11.49 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45940 461
Hsd:SD percent change in left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 8 post-ischemic value/pre-ischemic value x 100% 25.36 % 4.89 13.83 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46962 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 6.53 mmHg 0.12 0.21 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48011 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 2 10.98 ml/min/g 0.1 0.13 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46159 461
Hsd:SD heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 7 52.0 mmHg 4.19 11.08 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47060 461
Hsd:SD heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 11 39.18 mmHg 5.05 16.75 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47061 461
Hsd:SD time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 7 855.83 s 59.11 156.4 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45026 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 13 12.15 ml/min/g 1.17 4.22 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45052 461
Hsd:SD time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 922.41 s 22.76 39.42 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45069 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 3 9.99 ml/min/g 1.73 2.99 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45086 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 3 9.7 ml/min/g 0.85 1.47 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45090 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 9 0.28 IU/g 0.06 0.17 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45131 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 65.39 % 8.7 28.85 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46293 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 3 0.07 IU/g 0.01 0.01 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45235 461
Hsd:SD heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 11 48.89 mmHg 4.88 16.18 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49161 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 3 117.54 mmHg 9.47 16.4 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49281 461
Hsd:SD percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 post-ischemic value/pre-ischemic value x 100% 75.29 % 7.5 21.2 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49625 461
Hsd:SD time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 7 625.0 s 64.18 169.8 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49647 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 127.92 mmHg 8.06 11.4 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49789 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 post-ischemic value/pre-ischemic value x 100% 76.76 % 4.67 14.77 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49813 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 3 32.0 % 4.07 7.04 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49859 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 306.3 beats/min 21.43 37.12 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49975 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 6 17.99 IU/g 4.36 10.69 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45487 461
Hsd:SD percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 11 post-ischemic value/pre-ischemic value x 100% 32.31 % 6.95 23.05 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46530 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 264.79 beats/min 37.41 105.8 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46631 461
Hsd:SD percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 87.98 % 9.8 16.98 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47545 461
Hsd:SD percent change in heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 post-ischemic value/pre-ischemic value x 100% 89.71 % 4.41 6.24 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47549 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 6 0.13 IU/g 0.04 0.09 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48706 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 49.4 mmHg 11.63 20.14 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45936 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 6.32 ml/min/g 0.41 1.23 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46853 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 9 10.59 ml/min/g 0.65 1.96 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46019 461
Hsd:SD arterial blood flow rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 12 11.48 ml/min/g 0.81 2.81 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46020 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 119.24 mmHg 4.29 7.43 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46044 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 10 30.4 mmHg 6.89 21.77 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46149 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 100.78 % 8.56 14.83 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46167 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 3 7.07 ml/min/g 0.32 0.55 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46183 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 3 0.89 IU/g 0.61 1.06 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47177 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 6.83 mmHg 0.25 0.35 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48165 461
Hsd:SD percent change in left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 50.64 % 6.24 10.81 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45045 461
Hsd:SD time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 999.13 s 172.26 243.62 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45073 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity female 49.0 days-63.0 days 12 0.41 IU/g 0.07 0.26 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45132 461
Hsd:SD heart contraction pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 2 80.0 mmHg 4.0 5.66 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47388 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 60.91 mmHg 9.31 16.13 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47396 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 58.96 mmHg 6.17 8.73 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 47412 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 9 10.56 IU/g 1.36 4.07 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47415 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 7 35.12 mmHg 6.77 17.91 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48389 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 11 35.73 mmHg 8.44 28.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48390 461
Hsd:SD left ventricular diastolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 11 4.73 mmHg 0.27 0.9 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49044 461
Hsd:SD heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 13 49.58 mmHg 4.1 14.78 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49160 461
Hsd:SD percent change in heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 post-ischemic value/pre-ischemic value x 100% 86.24 % 8.12 14.06 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49265 461
Hsd:SD time to onset of heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 2 482.34 s 0.0 0.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49488 461
Hsd:SD heart contraction pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 3 63.33 mmHg 11.57 20.03 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49592 461
Hsd:SD left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 8 124.98 mmHg 8.52 24.1 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49649 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 7 77.98 mmHg 13.78 36.46 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49645 461
Hsd:SD left ventricular systolic blood pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 3 122.27 mmHg 9.19 15.92 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49785 461
Hsd:SD percent change in left ventricular systolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 post-ischemic value/pre-ischemic value x 100% 66.38 % 10.23 28.94 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49812 461
Hsd:SD heart left ventricle infarction weight to total heart left ventricle weight ratio controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) PhysGen Cardiac data heart left ventricle integrity trait male 49.0 days-63.0 days 13 15.23 % 2.26 8.15 digital scale post excision weight measurement Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48739 461
Hsd:SD left ventricular developed pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 9 111.22 mmHg 7.0 20.99 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47785 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 13 5.82 ml/min/g 0.48 1.72 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46841 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait female 49.0 days-63.0 days 10 7.09 ml/min/g 0.94 2.97 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46842 461
Hsd:SD time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 13 699.88 s 51.24 184.76 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 47894 461
Hsd:SD left ventricular developed pressure controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait female 49.0 days-63.0 days 2 123.06 mmHg 1.47 2.07 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46048 461
Hsd:SD arterial blood flow rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data arterial blood flow trait male 49.0 days-63.0 days 3 8.32 ml/min/g 1.98 3.42 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46179 461
Hsd:SD time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait male 49.0 days-63.0 days 2 90.87 s 18.17 25.7 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48123 461
Hsd:SD time to onset of heart contraction controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 3 102.04 s 0.0 0.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48127 461
Hsd:SD left ventricular diastolic blood pressure controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart left ventricular blood pressure trait male 49.0 days-63.0 days 7 5.57 mmHg 0.9 2.37 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 48168 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 295.8 beats/min 14.55 20.57 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48179 461
Hsd:SD time to peak heart contraction controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) PhysGen Cardiac data heart muscle contractility trait female 49.0 days-63.0 days 11 988.67 s 45.4 150.59 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 45027 461
Hsd:SD heart effluent lactate dehydrogenase activity level normalized to heart weight controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart lactate dehydrogenase activity male 49.0 days-63.0 days 3 0.02 IU/g 0.01 0.01 isolated perfused heart effluent collection Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 48382 461
Hsd:SD heart rate controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 264.71 beats/min 0.0 0.0 balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 45361 461