Crl:CD(SD) |
heart contraction pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
47.1 |
mmHg |
2.59 |
8.18 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49591 |
461 |
Crl:CD(SD) |
percent change in left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
58.7 |
% |
10.36 |
32.75 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49655 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
|
148.93 |
mmHg |
4.34 |
13.73 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49804 |
461 |
Crl:CD(SD) |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
10 |
|
15.05 |
% |
4.75 |
15.03 |
digital scale post excision weight measurement |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49856 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
95.76 |
mmHg |
10.85 |
32.56 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49276 |
461 |
Crl:CD(SD) |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
332.0 |
beats/min |
62.39 |
197.29 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46501 |
461 |
Crl:CD(SD) |
percent change in left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
27.46 |
% |
7.86 |
24.85 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47522 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
56.35 |
mmHg |
5.11 |
16.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45933 |
461 |
Crl:CD(SD) |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
67.84 |
% |
7.4 |
23.42 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47886 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
5.3 |
mmHg |
0.12 |
0.36 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48010 |
461 |
Crl:CD(SD) |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
52.16 |
% |
2.18 |
6.55 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45854 |
461 |
Crl:CD(SD) |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
1257.86 |
s |
68.22 |
215.74 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45066 |
461 |
Crl:CD(SD) |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
9 |
|
0.45 |
IU/g |
0.25 |
0.74 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48379 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
9 |
|
13.27 |
ml/min/g |
1.12 |
3.36 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46154 |
461 |
Crl:CD(SD) |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49 days-63 days |
10 |
|
9.36 |
% |
4.43 |
14.02 |
digital scale post excision weight measurement |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49030 |
461 |
Crl:CD(SD) |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
10 |
|
6.65 |
% |
3.61 |
11.4 |
digital scale post excision weight measurement |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49032 |
461 |
Crl:CD(SD) |
percent change in heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
96.68 |
% |
10.15 |
32.1 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49264 |
461 |
Crl:CD(SD) |
heart contraction pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
49.4 |
mmHg |
4.69 |
14.84 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49589 |
461 |
Crl:CD(SD) |
percent change in left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
67.51 |
% |
6.43 |
20.33 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49653 |
461 |
Crl:CD(SD) |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49 days-63 days |
10 |
|
7.16 |
% |
4.64 |
14.66 |
digital scale post excision weight measurement |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49858 |
461 |
Crl:CD(SD) |
percent change in left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
25.51 |
% |
8.58 |
27.14 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47524 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
142.0 |
mmHg |
4.41 |
13.24 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47668 |
461 |
Crl:CD(SD) |
time to onset of heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
831.13 |
s |
52.0 |
164.45 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48120 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
5.19 |
mmHg |
0.27 |
0.82 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48158 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
7 |
|
123.91 |
mmHg |
6.22 |
16.46 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45016 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
7 |
|
114.13 |
mmHg |
6.85 |
18.12 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45018 |
461 |
Crl:CD(SD) |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
63.54 |
% |
2.82 |
8.92 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47884 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
10 |
|
12.7 |
ml/min/g |
3.58 |
11.33 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46178 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
7 |
|
118.81 |
mmHg |
6.51 |
17.21 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46041 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
7 |
|
108.65 |
mmHg |
6.86 |
18.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46043 |
461 |
Crl:CD(SD) |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
251.21 |
beats/min |
6.4 |
19.2 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45354 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
48.23 |
mmHg |
6.22 |
18.66 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47405 |
461 |
Crl:CD(SD) |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49 days-63 days |
7 |
|
0.19 |
IU/g |
0.07 |
0.19 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45232 |
461 |
Crl:CD(SD) |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
87.4 |
% |
9.53 |
25.22 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46166 |
461 |
Crl:CD(SD) |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
250.69 |
beats/min |
6.17 |
19.5 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49974 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
98.3 |
mmHg |
9.41 |
26.61 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49784 |
461 |
Crl:CD(SD) |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
90.89 |
% |
2.83 |
8.01 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47544 |
461 |
Crl:CD(SD) |
percent change in heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
131.59 |
% |
25.95 |
82.05 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49262 |
461 |
Crl:CD(SD) |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
943.5 |
s |
95.47 |
301.9 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49483 |
461 |
Crl:CD(SD) |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
257.17 |
beats/min |
13.09 |
41.4 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49972 |
461 |
Crl:CD(SD) |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
94.12 |
% |
2.29 |
6.87 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47542 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
130.92 |
mmHg |
5.55 |
17.56 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47666 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
34.85 |
mmHg |
9.36 |
29.59 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45903 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
43.91 |
mmHg |
11.55 |
32.66 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45905 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
9 |
|
59.39 |
mmHg |
4.85 |
14.54 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45935 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
5.73 |
mmHg |
0.11 |
0.35 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48008 |
461 |
Crl:CD(SD) |
time to peak heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
10 |
|
1139.63 |
s |
43.43 |
137.34 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45103 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
|
10.7 |
ml/min/g |
0.4 |
1.19 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46152 |
461 |
Crl:CD(SD) |
time to onset of heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
870.38 |
s |
51.09 |
161.57 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48122 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
8 |
|
5.5 |
mmHg |
0.1 |
0.28 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48160 |
461 |
Crl:CD(SD) |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
9 |
|
268.08 |
beats/min |
8.94 |
26.82 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48172 |
461 |
Crl:CD(SD) |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
58.88 |
% |
11.71 |
30.98 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45044 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
9 |
|
14.61 |
ml/min/g |
0.64 |
1.91 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45085 |
461 |
Crl:CD(SD) |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
81.28 |
% |
4.11 |
10.87 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46164 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
99.6 |
mmHg |
3.83 |
11.5 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49782 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
91.21 |
mmHg |
7.78 |
24.59 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49274 |
461 |
Crl:CD(SD) |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
245.03 |
beats/min |
30.09 |
95.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46503 |
461 |
Crl:CD(SD) |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
59.6 |
% |
6.76 |
20.29 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45856 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
9 |
|
5.57 |
ml/min/g |
0.28 |
0.84 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45891 |
461 |
Crl:CD(SD) |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
40.0 |
% |
4.91 |
12.98 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45042 |
461 |
Crl:CD(SD) |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
50.3 |
mmHg |
3.23 |
10.21 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47381 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
9 |
|
51.37 |
mmHg |
5.7 |
17.1 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47393 |
461 |
Crl:CD(SD) |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
9 |
|
0.2 |
IU/g |
0.05 |
0.15 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48381 |
461 |
Crl:CD(SD) |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49 days-63 days |
10 |
|
136.65 |
mmHg |
5.53 |
17.49 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49802 |
461 |
Crl:CD(SD) |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49 days-63 days |
10 |
|
971.74 |
s |
41.6 |
131.56 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
49481 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49 days-63 days |
9 |
|
7.77 |
ml/min/g |
0.98 |
2.93 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45893 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
|
9.37 |
ml/min/g |
0.51 |
1.62 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46176 |
461 |
Crl:CD(SD) |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
1197.3 |
s |
78.37 |
247.83 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45068 |
461 |
Crl:CD(SD) |
time to peak heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
10 |
|
1139.17 |
s |
46.23 |
146.19 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45105 |
461 |
Crl:CD(SD) |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49 days-63 days |
10 |
|
41.6 |
mmHg |
5.17 |
16.35 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47383 |
461 |
Crl:CD(SD) |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
|
250.21 |
beats/min |
6.3 |
17.81 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45356 |
461 |
Crl:CD(SD) |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49 days-63 days |
8 |
|
276.52 |
beats/min |
8.41 |
23.79 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48174 |
461 |
Crl:CD(SD) |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49 days-63 days |
10 |
|
14.76 |
ml/min/g |
0.5 |
1.58 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45083 |
461 |
Crl:CD(SD) |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
7 |
|
75.38 |
mmHg |
5.16 |
13.65 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47395 |
461 |
Crl:CD(SD) |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49 days-63 days |
7 |
|
31.89 |
mmHg |
7.44 |
19.68 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47407 |
461 |
Crl:CD(SD) |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49 days-63 days |
7 |
|
0.28 |
IU/g |
0.07 |
0.19 |
isolated perfused heart effluent collection |
|
0 |
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45234 |
461 |