Phenominer Database Results (12 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
SS.BN-(D12Arb13-D12Rat79)/Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 12 0.88 E-7mole 0.18 0.62 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 56496 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 12 -7.15 null 0.08 0.29 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 56891 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 14 48.64 % 5.0 18.71 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 57208 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 11 52.09 % 4.31 14.31 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 54764 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 11 0.91 E-7mole 0.19 0.62 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 56504 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 14 43.21 % 3.14 11.75 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 57200 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 14 -6.94 null 0.1 0.37 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 55601 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 12 45.83 % 4.05 14.04 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 54756 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 14 1.55 E-7mole 0.32 1.21 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 55878 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 14 -6.97 null 0.12 0.44 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 55609 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait male 70.0 days-84.0 days 14 1.53 E-7mole 0.3 1.12 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 55870 522
SS.BN-(D12Arb13-D12Rat79)/Mcwi logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) PhysGen Vascular data vasodilation trait female 70.0 days-84.0 days 11 -7.15 null 0.1 0.34 wire myography using a Digi-Med tissue force analysis system with force transducer Moms and pups used in studies were fed Teklad 56899 522