| SS-Chr 5BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
10 |
-7.06 |
null |
0.07 |
0.22 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
55627 |
522 |
| SS-Chr 5BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
10 |
0.98 |
E-7mole |
0.17 |
0.55 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
55896 |
522 |
| SS-Chr 5BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
8 |
1.93 |
E-7mole |
0.35 |
0.98 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
55901 |
522 |
| SS-Chr 5BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
11 |
87.91 |
% |
3.41 |
11.32 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
54782 |
522 |
| SS-Chr 5BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
8 |
88.13 |
% |
6.08 |
17.19 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
54787 |
522 |
| SS-Chr 5BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
8 |
-6.78 |
null |
0.1 |
0.27 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
55632 |
522 |
| SS-Chr 5BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
11 |
1.34 |
E-7mole |
0.1 |
0.32 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
56522 |
522 |
| SS-Chr 5BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
11 |
-6.88 |
null |
0.03 |
0.1 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
56917 |
522 |
| SS-Chr 5BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
8 |
-6.87 |
null |
0.08 |
0.24 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
56922 |
522 |
| SS-Chr 5BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
10 |
91.8 |
% |
2.85 |
9.02 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
57226 |
522 |
| SS-Chr 5BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
8 |
86.38 |
% |
8.85 |
25.03 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
57231 |
522 |
| SS-Chr 5BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
8 |
1.52 |
E-7mole |
0.22 |
0.64 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
56527 |
522 |