| WKY/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
10 |
12.06 |
ml/min/kg |
1.4 |
4.42 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58841 |
526 |
| WKY/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
9 |
8.73 |
ml/min/kg |
0.78 |
2.34 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
59860 |
526 |
| WKY/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
10 |
7.96 |
ml/min/kg |
0.54 |
1.72 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
59867 |
526 |
| WKY/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
13 |
0.22 |
null |
0.01 |
0.05 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57740 |
526 |
| WKY/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
9 |
0.33 |
null |
0.03 |
0.08 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58579 |
526 |
| WKY/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
13 |
13.65 |
ml/min/kg |
1.26 |
4.53 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57456 |
526 |
| WKY/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
13 |
18.51 |
ml/min/kg |
1.21 |
4.38 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58311 |
526 |
| WKY/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
9 |
12.88 |
ml/min/kg |
1.79 |
5.37 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58834 |
526 |
| WKY/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
7 |
0.25 |
null |
0.03 |
0.09 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57733 |
526 |
| WKY/NCrl |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
9 |
0.34 |
null |
0.01 |
0.04 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58572 |
526 |
| WKY/NCrl |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
7 |
7.91 |
ml/min/kg |
1.06 |
2.79 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57449 |
526 |
| WKY/NCrl |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
7 |
14.33 |
ml/min/kg |
2.03 |
5.38 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58304 |
526 |