| Crl:CD(SD) |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
7 |
0.26 |
null |
0.02 |
0.05 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58574 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
8 |
6.28 |
ml/min/kg |
0.36 |
1.01 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58836 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
8 |
5.48 |
ml/min/kg |
0.35 |
0.99 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
59862 |
526 |
| Crl:CD(SD) |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
8 |
0.22 |
null |
0.02 |
0.05 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57737 |
526 |
| Crl:CD(SD) |
methylene blue to FAPGG metabolism-surface area product ratio |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
9 |
0.26 |
null |
0.04 |
0.12 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57735 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
8 |
8.25 |
ml/min/kg |
0.3 |
0.84 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58308 |
526 |
| Crl:CD(SD) |
methylene blue to FAPGG metabolism-surface area product ratio |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
10 |
0.22 |
null |
0.03 |
0.1 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58576 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product without auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
10 |
8.59 |
ml/min/kg |
0.74 |
2.34 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58838 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
9 |
5.28 |
ml/min/kg |
0.14 |
0.41 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57451 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product after auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
8 |
6.3 |
ml/min/kg |
0.19 |
0.55 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57453 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product without auto-oxidation |
methylene blue (10 umol/l) (between 0 and 0 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
male |
77.0 days-91.0 days |
9 |
6.26 |
ml/min/kg |
0.18 |
0.55 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
58306 |
526 |
| Crl:CD(SD) |
methylene blue metabolism-surface area product after auto-oxidation |
controlled air oxygen content (12 %) (for 14 days) then methylene blue (10 umol/l) (between 0 and 0 hours) then sample resting period (for 0.1 hours) |
PhysGen Lung data |
pulmonary blood flow trait |
female |
77.0 days-91.0 days |
10 |
7.65 |
ml/min/kg |
0.45 |
1.43 |
isolated perfused lung vascular effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
59864 |
526 |