| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
8 |
0.81 |
mg/kg |
0.17 |
0.48 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
58880 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
4 |
1.48 |
mg/kg |
0.21 |
0.43 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Dyets |
58599 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
17 |
1.35 |
mg/kg |
0.17 |
0.7 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Dyets |
58845 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
female |
77.0 days-91.0 days |
9 |
0.6 |
mg/kg |
0.16 |
0.49 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
58884 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
4 |
1.02 |
mg/kg |
0.17 |
0.34 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
58471 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
female |
77.0 days-91.0 days |
7 |
1.26 |
mg/kg |
0.45 |
1.18 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Dyets |
58604 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
female |
77.0 days-91.0 days |
13 |
1.11 |
mg/kg |
0.24 |
0.85 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Dyets |
58853 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
98 |
1.6 |
mg/kg |
0.11 |
1.12 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Teklad |
58973 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
88 |
1.36 |
mg/kg |
0.1 |
0.97 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Teklad |
59213 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
female |
77.0 days-91.0 days |
12 |
1.11 |
mg/kg |
0.17 |
0.6 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Teklad |
59221 |
526 |
| SS/JrHsdMcwi |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
female |
77.0 days-91.0 days |
9 |
1.32 |
mg/kg |
0.29 |
0.88 |
Download Values
|
stop flow air displacement plethysmography |
|
|
Moms and pups used in studies were fed Teklad |
58978 |
526 |