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Strain
Phenotype
Conditions
Study
Experiment Name
Sex
Age
# of Animals
Value
Units
SEM
SD
Individual Records
Method
Method Duration
Post Insult Time Value
Experiment Notes
Record ID
Study ID
Hsd:SD
dose of methacholine at which pulmonary conductance is half its pretreatment value
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)
PhysGen Lung data
pulmonary ventilation trait
female
77.0 days-91.0 days
5
1.01
mg/kg
0.28
0.63
Download Values
stop flow air displacement plethysmography
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks
58883
526
Hsd:SD
dose of methacholine at which pulmonary conductance is half its pretreatment value
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)
PhysGen Lung data
pulmonary ventilation trait
female
77.0 days-91.0 days
4
1.42
mg/kg
0.31
0.63
Download Values
stop flow air displacement plethysmography
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan
57983
526
Hsd:SD
dose of methacholine at which pulmonary conductance is half its pretreatment value
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)
PhysGen Lung data
pulmonary ventilation trait
male
77.0 days-91.0 days
8
1.52
mg/kg
0.29
0.81
Download Values
stop flow air displacement plethysmography
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan
57982
526
Hsd:SD
dose of methacholine at which pulmonary conductance is half its pretreatment value
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)
PhysGen Lung data
pulmonary ventilation trait
female
77.0 days-91.0 days
7
0.8
mg/kg
0.15
0.39
Download Values
stop flow air displacement plethysmography
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan
58593
526
Hsd:SD
dose of methacholine at which pulmonary conductance is half its pretreatment value
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)
PhysGen Lung data
pulmonary ventilation trait
male
77.0 days-91.0 days
7
1.75
mg/kg
0.34
0.89
Download Values
stop flow air displacement plethysmography
Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan
58592
526
Hsd:SD
dose of methacholine at which pulmonary conductance is half its pretreatment value
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours)
PhysGen Lung data
pulmonary ventilation trait
male
77.0 days-91.0 days
7
1.61
mg/kg
0.31
0.83
Download Values
stop flow air displacement plethysmography
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks
58881
526