| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
1 |
31.77 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51868 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
6 |
21.1 |
mmHg |
4.61 |
11.29 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51871 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
6 |
19.47 |
mmHg |
4.39 |
10.76 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51972 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
1 |
13.4 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50584 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
6 |
1.29 |
mmHg |
2.0 |
4.9 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50607 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
1 |
-21.2 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50682 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
1 |
8.33 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50915 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
1 |
31.89 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50931 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
1 |
23.0 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50508 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
6 |
11.69 |
mmHg |
6.31 |
15.46 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50934 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
1 |
15.43 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51105 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
6 |
-37.73 |
beats/min |
10.68 |
26.16 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51375 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
1 |
24.43 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51965 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
1 |
24.4 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50722 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
6 |
-11.63 |
beats/min |
18.33 |
44.89 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50725 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
6 |
6.71 |
mmHg |
3.2 |
7.84 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51108 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
6 |
-0.23 |
mmHg |
3.97 |
9.71 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51138 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
1 |
-22.2 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51235 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
6 |
12.97 |
beats/min |
16.28 |
39.87 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50426 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
6 |
31.47 |
beats/min |
18.3 |
44.84 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50511 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
6 |
31.28 |
mmHg |
4.3 |
10.52 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51776 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
1 |
-16.4 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51922 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
1 |
75.2 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
52053 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
1 |
3.22 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50604 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
6 |
-14.23 |
beats/min |
4.03 |
9.87 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50689 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
1 |
-1.39 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50776 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
1 |
21.07 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51661 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
6 |
26.33 |
mmHg |
3.02 |
7.4 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51668 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
1 |
-32.2 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50357 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
1 |
15.69 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51773 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
6 |
-12.28 |
beats/min |
7.95 |
19.48 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51929 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
6 |
-11.07 |
beats/min |
14.76 |
36.15 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
52056 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
6 |
-30.8 |
beats/min |
7.68 |
18.82 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50591 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
6 |
4.02 |
mmHg |
8.2 |
20.09 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50783 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
6 |
2.79 |
mmHg |
5.37 |
13.15 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50922 |
481 |
| SHR/NCrl |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
1 |
6.51 |
mmHg |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51131 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
6 |
-14.73 |
beats/min |
16.5 |
40.43 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
51242 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
1 |
2.2 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
51372 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
6 |
-12.88 |
beats/min |
7.63 |
18.69 |
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Teklad |
50364 |
481 |
| SHR/NCrl |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
1 |
105.2 |
beats/min |
|
|
vascular fluid filled catheter |
|
|
Moms and pups used in studies were fed Dyets |
50423 |
481 |