| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
8 |
|
13.05 |
mmHg |
2.64 |
7.47 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51874 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
4 |
|
2.63 |
mmHg |
2.19 |
4.39 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50609 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
8 |
|
0.7 |
mmHg |
0.63 |
1.77 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50610 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
4 |
|
3.95 |
mmHg |
4.82 |
9.64 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50936 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
4 |
|
8.96 |
mmHg |
2.29 |
4.57 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51110 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
8 |
|
0.6 |
mmHg |
0.68 |
1.94 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51111 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
4 |
|
0.75 |
beats/min |
17.84 |
35.68 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51377 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
8 |
|
-34.84 |
beats/min |
18.09 |
51.17 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50362 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
4 |
|
-3.15 |
beats/min |
20.75 |
41.49 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50428 |
481 |
| BN/NHsdMcwi |
mean arterial blood pressure |
furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
arterial blood pressure trait |
female |
101.0 days-103.0 days |
20 |
serial mean |
135.6 |
mmHg |
3.2 |
14.31 |
vascular indwelling catheter method |
left femoral artery |
120.0 |
|
|
|
69539 |
151 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
8 |
|
7.17 |
beats/min |
11.83 |
33.45 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51927 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
8 |
|
7.06 |
mmHg |
2.33 |
6.6 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51970 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
8 |
|
2.83 |
beats/min |
19.88 |
56.24 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50687 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
4 |
|
34.55 |
beats/min |
25.93 |
51.86 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50688 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
8 |
|
2.23 |
mmHg |
1.67 |
4.71 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50937 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
8 |
|
10.88 |
beats/min |
4.58 |
12.97 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51378 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
arterial blood pressure trait |
female |
101.0 days-103.0 days |
19 |
serial mean |
22.0 |
mmHg |
3.0 |
13.08 |
vascular indwelling catheter method |
left femoral artery |
0.0 |
|
|
|
67301 |
151 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
4 |
|
19.38 |
mmHg |
3.3 |
6.6 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51873 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
8 |
|
-6.25 |
beats/min |
7.6 |
21.49 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
52059 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
4 |
|
20.6 |
beats/min |
13.45 |
26.91 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50513 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
4 |
|
-24.45 |
beats/min |
31.16 |
62.33 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50590 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
8 |
|
4.68 |
mmHg |
2.12 |
5.99 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50920 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
4 |
|
31.19 |
mmHg |
2.1 |
4.2 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51667 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
8 |
|
-8.48 |
beats/min |
15.29 |
43.23 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50429 |
481 |
| BN/NHsdMcwi |
mean arterial blood pressure |
furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (0.5 ug/kg/min) (for 0.1 hours) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
arterial blood pressure trait |
female |
101.0 days-103.0 days |
21 |
serial mean |
120.4 |
mmHg |
5.3 |
24.29 |
vascular indwelling catheter method |
left femoral artery |
120.0 |
|
|
|
69535 |
151 |
| BN/NHsdMcwi |
mean arterial blood pressure |
furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (1 ug/kg/min) (for 0.1 hours) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
arterial blood pressure trait |
female |
101.0 days-103.0 days |
21 |
serial mean |
128.6 |
mmHg |
4.0 |
18.33 |
vascular indwelling catheter method |
left femoral artery |
120.0 |
|
|
|
69537 |
151 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
4 |
|
-26.7 |
beats/min |
9.39 |
18.78 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51928 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
4 |
|
8.94 |
mmHg |
2.68 |
5.36 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51971 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
4 |
|
-6.75 |
beats/min |
8.96 |
17.92 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
52058 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
8 |
|
-47.96 |
beats/min |
18.32 |
51.83 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50589 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
8 |
|
-25.21 |
beats/min |
19.43 |
54.97 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50728 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
4 |
|
-12.7 |
beats/min |
20.48 |
40.96 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50727 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
4 |
|
5.65 |
mmHg |
0.84 |
1.68 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50782 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
4 |
|
5.4 |
mmHg |
1.79 |
3.58 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50921 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
4 |
|
8.88 |
mmHg |
3.75 |
7.51 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51137 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
4 |
|
-11.35 |
beats/min |
12.39 |
24.77 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51241 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
4 |
|
-45.27 |
beats/min |
22.01 |
44.02 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50363 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
4 |
|
30.33 |
mmHg |
2.51 |
5.03 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51778 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
female |
87.0 days-120.0 days |
8 |
|
16.08 |
mmHg |
3.41 |
9.65 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
51779 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
female |
87.0 days-120.0 days |
8 |
|
32.45 |
beats/min |
10.27 |
29.06 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Dyets |
50514 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
8 |
|
3.46 |
mmHg |
1.52 |
4.29 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
50781 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
8 |
|
0.1 |
mmHg |
1.74 |
4.93 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51136 |
481 |
| BN/NHsdMcwi |
absolute change in heart rate |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
heart pumping trait |
male |
87.0 days-120.0 days |
8 |
|
-1.39 |
beats/min |
7.41 |
20.95 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51240 |
481 |
| BN/NHsdMcwi |
absolute change in mean arterial blood pressure |
controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) |
PhysGen Renal A data |
arterial blood pressure trait |
male |
87.0 days-120.0 days |
8 |
|
23.04 |
mmHg |
2.89 |
8.17 |
vascular fluid filled catheter |
|
|
|
|
Moms and pups used in studies were fed Teklad |
51666 |
481 |
| BN/NHsdMcwi |
ratio of change in renal blood flow rate to kidney weight |
controlled sodium content diet (0.4 %) (for 16 hours) then norepinephrine (3 ug/kg/min) (for 0.1 hours) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
renal blood flow trait |
female |
97.0 days-101.0 days |
19 |
|
-1.4 |
ml/min/g |
0.2 |
0.87 |
electromagnetic flowmetry |
|
0.0 |
|
electromagnetic flowmetry |
|
67307 |
151 |