| SS-Chr 12BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49.0 days-63.0 days |
9 |
|
223.45 |
beats/min |
16.3 |
48.91 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48970 |
461 |
| SS-Chr 12BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49.0 days-63.0 days |
9 |
|
14.59 |
% |
0.9 |
2.7 |
digital scale post excision weight measurement |
|
|
Moms and pups used in studies were fed Teklad |
49417 |
461 |
| SS-Chr 12BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49.0 days-63.0 days |
9 |
|
936.33 |
s |
29.83 |
89.48 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
50144 |
461 |
| SS-Chr 12BN/Mcwi |
time to peak heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49.0 days-63.0 days |
10 |
|
1079.9 |
s |
30.41 |
96.17 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
50252 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
10 |
|
40.6 |
mmHg |
6.49 |
20.54 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
46438 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular diastolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
10 |
|
52.86 |
mmHg |
3.32 |
10.49 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
46442 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
78.2 |
% |
6.58 |
20.82 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48777 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
9 |
|
55.18 |
mmHg |
4.49 |
13.46 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
47726 |
461 |
| SS-Chr 12BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
10 |
|
4.18 |
ml/min/g |
0.39 |
1.24 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
44743 |
461 |
| SS-Chr 12BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49.0 days-63.0 days |
10 |
|
34.3 |
mmHg |
2.06 |
6.52 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48058 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
51.91 |
% |
3.03 |
9.1 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
46091 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
41.21 |
% |
3.77 |
10.67 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
46087 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
42.29 |
% |
3.17 |
10.03 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
47102 |
461 |
| SS-Chr 12BN/Mcwi |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49.0 days-63.0 days |
8 |
|
197.99 |
beats/min |
5.97 |
16.89 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
45173 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49.0 days-63.0 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
68.44 |
% |
6.41 |
18.13 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48427 |
461 |
| SS-Chr 12BN/Mcwi |
heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49.0 days-63.0 days |
8 |
|
170.75 |
beats/min |
15.63 |
44.2 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48966 |
461 |
| SS-Chr 12BN/Mcwi |
time to onset of heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49.0 days-63.0 days |
10 |
|
883.5 |
s |
25.53 |
80.74 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
49324 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
10 |
|
81.85 |
mmHg |
2.26 |
7.16 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
49913 |
461 |
| SS-Chr 12BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49.0 days-63.0 days |
10 |
|
12.57 |
IU/g |
2.32 |
7.35 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
46004 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
7 |
|
39.41 |
mmHg |
2.73 |
7.22 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
47932 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
9 |
|
90.3 |
mmHg |
5.27 |
15.81 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
44840 |
461 |
| SS-Chr 12BN/Mcwi |
heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49.0 days-63.0 days |
10 |
|
227.39 |
beats/min |
5.69 |
18.0 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
45169 |
461 |
| SS-Chr 12BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
8 |
|
3.36 |
ml/min/g |
0.28 |
0.78 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
46222 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
41.26 |
% |
4.44 |
13.33 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
46344 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in heart rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49.0 days-63.0 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
86.03 |
% |
11.36 |
34.07 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48431 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
10 |
|
28.99 |
mmHg |
2.96 |
9.36 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
45295 |
461 |
| SS-Chr 12BN/Mcwi |
heart contraction pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49.0 days-63.0 days |
9 |
|
28.33 |
mmHg |
3.4 |
10.19 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
50018 |
461 |
| SS-Chr 12BN/Mcwi |
heart contraction pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
female |
49.0 days-63.0 days |
10 |
|
30.8 |
mmHg |
2.58 |
8.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
50022 |
461 |
| SS-Chr 12BN/Mcwi |
time to onset of heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49.0 days-63.0 days |
9 |
|
859.78 |
s |
12.56 |
37.68 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
50140 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
89.61 |
% |
2.61 |
8.26 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48781 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
7 |
|
101.8 |
mmHg |
6.85 |
18.12 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
44836 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49.0 days-63.0 days |
8 |
post-ischemic value/pre-ischemic value x 100% |
82.61 |
% |
3.47 |
9.8 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48320 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular systolic blood pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
10 |
|
67.78 |
mmHg |
8.57 |
27.09 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
49909 |
461 |
| SS-Chr 12BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49.0 days-63.0 days |
9 |
|
1041.89 |
s |
18.53 |
55.59 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
46569 |
461 |
| SS-Chr 12BN/Mcwi |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 1.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49.0 days-63.0 days |
7 |
|
8.76 |
IU/g |
1.36 |
3.61 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
46010 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
9 |
|
35.12 |
mmHg |
4.2 |
12.6 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
47936 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
115.99 |
% |
5.89 |
15.58 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
44939 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular systolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
99.65 |
% |
4.15 |
12.44 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
44943 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
10 |
|
27.17 |
mmHg |
4.91 |
15.53 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
45291 |
461 |
| SS-Chr 12BN/Mcwi |
time to onset of heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49.0 days-63.0 days |
10 |
|
887.3 |
s |
53.31 |
168.57 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
49320 |
461 |
| SS-Chr 12BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49.0 days-63.0 days |
9 |
|
7.38 |
% |
1.54 |
4.61 |
digital scale post excision weight measurement |
|
|
Moms and pups used in studies were fed Teklad |
49421 |
461 |
| SS-Chr 12BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
male |
49.0 days-63.0 days |
10 |
|
18.75 |
% |
2.96 |
9.36 |
digital scale post excision weight measurement |
|
|
Moms and pups used in studies were fed Teklad |
49719 |
461 |
| SS-Chr 12BN/Mcwi |
heart left ventricle infarction weight to total heart left ventricle weight ratio |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 3 hours) |
PhysGen Cardiac data |
heart left ventricle integrity trait |
female |
49.0 days-63.0 days |
9 |
|
10.34 |
% |
1.49 |
4.47 |
digital scale post excision weight measurement |
|
|
Moms and pups used in studies were fed Teklad |
49723 |
461 |
| SS-Chr 12BN/Mcwi |
time to peak heart contraction |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49.0 days-63.0 days |
10 |
|
1102.7 |
s |
47.78 |
151.09 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
50248 |
461 |
| SS-Chr 12BN/Mcwi |
time to peak heart contraction |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart pumping trait |
female |
49.0 days-63.0 days |
10 |
|
1153.4 |
s |
16.63 |
52.58 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
46573 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
female |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
33.39 |
% |
3.14 |
9.93 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48552 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular developed pressure |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
32.58 |
% |
4.79 |
15.16 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48548 |
461 |
| SS-Chr 12BN/Mcwi |
left ventricular diastolic blood pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
7 |
|
62.39 |
mmHg |
4.88 |
12.91 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
47722 |
461 |
| SS-Chr 12BN/Mcwi |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
|
5.09 |
ml/min/g |
0.54 |
1.71 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
44739 |
461 |
| SS-Chr 12BN/Mcwi |
heart contraction pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) |
PhysGen Cardiac data |
heart muscle contractility trait |
male |
49.0 days-63.0 days |
9 |
|
40.56 |
mmHg |
3.37 |
10.11 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48054 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
45.22 |
% |
3.81 |
12.06 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
47098 |
461 |
| SS-Chr 12BN/Mcwi |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
9 |
|
5.16 |
ml/min/g |
0.48 |
1.44 |
isolated perfused heart effluent collection |
|
|
Moms and pups used in studies were fed Teklad |
46226 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in left ventricular developed pressure |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart left ventricular blood pressure trait |
male |
49.0 days-63.0 days |
7 |
post-ischemic value/pre-ischemic value x 100% |
48.66 |
% |
3.91 |
10.35 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
46340 |
461 |
| SS-Chr 12BN/Mcwi |
percent change in heart rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart pumping trait |
male |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
82.73 |
% |
2.36 |
7.46 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
|
Moms and pups used in studies were fed Teklad |
48316 |
461 |