| GK |
systolic blood pressure |
vehicle control condition (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
|
|
145.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
|
|
|
|
measured 12 hr/day for 4 weeks |
daytime measurement |
103528 |
2827 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then artificial aortocaval fistula (for 4 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 6 |
undefined |
|
103.0 |
mmHg |
6.0 |
14.7 |
tail cuff plethysmography |
|
0.0 |
acf |
4 |
days |
|
|
101346 |
2585 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then artificial aortocaval fistula (for 2 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 5 |
undefined |
|
125.0 |
mmHg |
10.0 |
22.36 |
tail cuff plethysmography |
|
0.0 |
acf |
2 |
days |
|
|
101356 |
2585 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then sham surgical control condition (for 2 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 6 |
undefined |
|
150.0 |
mmHg |
4.0 |
9.8 |
tail cuff plethysmography |
|
0.0 |
sham acf |
2 |
days |
|
|
101357 |
2585 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then artificial aortocaval fistula (for 7 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 6 |
undefined |
|
123.0 |
mmHg |
3.0 |
7.35 |
tail cuff plethysmography |
|
0.0 |
acf |
7 |
days |
|
|
101364 |
2585 |
| LH/Mav |
systolic blood pressure |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
arterial blood pressure trait |
male |
56.0 days
| 11 |
mean of 3 samples of undefined duration |
serial mean |
134.0 |
mmHg |
4.0 |
13.27 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102704 |
2721 |
| SS-Nppbem2Mcwi-/- |
systolic blood pressure |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
168.0 days
| 7 |
|
serial mean |
195.0 |
mmHg |
30.0 |
79.37 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
99830 |
2319 |
| LH/Mav |
systolic blood pressure |
vehicle control condition |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
arterial blood pressure trait |
male |
49.0 days-56.0 days |
8 |
undefined |
|
136.0 |
mmHg |
3.0 |
8.49 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102645 |
2703 |
| SS/NEisSlc |
systolic blood pressure |
vehicle control condition (for 547.5 days) |
Hirawa N, et al., Hypertension. 1999 Sep;34(3):496-502. |
arterial blood pressure trait |
not specified |
547.0 days
| 10 |
|
|
137.0 |
mmHg |
3.0 |
9.49 |
vascular indwelling catheter method |
femoral artery |
0.0 |
|
|
|
|
|
106791 |
2339 |
| SHRSP/A3NCrl |
systolic blood pressure |
controlled sodium chloride content drinking water (1 %) (for 91 days) and controlled fat content diet (24.5 %) (for 91 days) then vehicle control condition (for 35 days) |
Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. |
arterial blood pressure trait |
male |
161.0 days-175.0 days |
6 |
|
|
162.0 |
mmHg |
4.0 |
9.8 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
107385 |
3083 |
| LL/Mav |
systolic blood pressure |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
arterial blood pressure trait |
male |
112.0 days
| 9 |
mean of 3 samples of undefined duration |
serial mean |
119.0 |
mmHg |
4.0 |
12.0 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102726 |
2721 |
| MW |
systolic blood pressure |
unilateral nephrectomy (for 70 days) then vehicle control condition |
Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. |
arterial blood pressure trait |
male |
days
| 7 |
undefined |
|
122.0 |
mmHg |
2.0 |
5.29 |
tail cuff plethysmography |
|
0.0 |
unx |
70 |
days |
|
|
101168 |
2581 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then artificial aortocaval fistula (for 7 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 7 |
undefined |
|
116.0 |
mmHg |
4.0 |
10.58 |
tail cuff plethysmography |
|
0.0 |
acf |
7 |
days |
|
|
101350 |
2585 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then artificial aortocaval fistula (for 9 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 7 |
undefined |
|
130.0 |
mmHg |
10.0 |
26.46 |
tail cuff plethysmography |
|
0.0 |
acf |
9 |
days |
|
|
101353 |
2585 |
| SS-Sod3m1Mcwi |
systolic blood pressure |
vehicle control condition |
Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. |
arterial blood pressure trait |
male |
56.0 days
| 8 |
|
|
115.0 |
mmHg |
5.22 |
14.76 |
vascular fluid filled catheter |
|
0.0 |
|
|
|
|
|
106803 |
3032 |
| LH/Mav |
systolic blood pressure |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
arterial blood pressure trait |
male |
112.0 days
| 11 |
mean of 3 samples of undefined duration |
serial mean |
160.0 |
mmHg |
4.0 |
13.27 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102728 |
2721 |
| GK |
systolic blood pressure |
vehicle control condition (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
|
|
145.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
|
|
|
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
103536 |
2827 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then sham surgical control condition (for 7 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 5 |
undefined |
|
130.0 |
mmHg |
2.0 |
4.47 |
tail cuff plethysmography |
|
0.0 |
sham acf |
7 |
days |
|
|
101351 |
2585 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then artificial aortocaval fistula (for 4 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 6 |
undefined |
|
122.0 |
mmHg |
3.0 |
7.35 |
tail cuff plethysmography |
|
0.0 |
acf |
4 |
days |
|
|
101360 |
2585 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then sham surgical control condition (for 4 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 5 |
undefined |
|
160.0 |
mmHg |
4.0 |
8.94 |
tail cuff plethysmography |
|
0.0 |
sham acf |
4 |
days |
|
|
101361 |
2585 |
| LL/Mav |
systolic blood pressure |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
arterial blood pressure trait |
male |
56.0 days
| 9 |
mean of 3 samples of undefined duration |
serial mean |
115.0 |
mmHg |
5.0 |
15.0 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102702 |
2721 |
| SS-Nppbem2Mcwi-/- |
systolic blood pressure |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
84.0 days
| 7 |
|
serial mean |
172.0 |
mmHg |
13.0 |
34.39 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
99828 |
2319 |
| SS/JrHsdMcwi |
systolic blood pressure |
vehicle control condition |
Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. |
arterial blood pressure trait |
male |
56.0 days
| 6 |
|
|
115.0 |
mmHg |
4.76 |
11.66 |
vascular fluid filled catheter |
|
0.0 |
|
|
|
|
|
106802 |
3032 |
| Crl:WI |
systolic blood pressure |
vehicle control condition (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
arterial blood pressure trait |
male |
112.0 days
| 10 |
|
|
126.9 |
mmHg |
4.0 |
12.65 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
109407 |
3140 |
| LH/Mav |
systolic blood pressure |
vehicle control condition |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
arterial blood pressure trait |
male |
63.0 days
| 8 |
undefined |
|
160.0 |
mmHg |
3.0 |
8.49 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102848 |
2761 |
| WKY/NCrl |
systolic blood pressure |
vehicle control condition (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
|
|
121.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
|
|
measured 12 hr/day for 4 weeks |
daytime measurement |
103526 |
2827 |
| WKY/NCrl |
systolic blood pressure |
vehicle control condition (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
|
|
126.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
|
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
103534 |
2827 |
| MW |
systolic blood pressure |
unilateral nephrectomy (for 14 days) then vehicle control condition |
Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. |
arterial blood pressure trait |
male |
days
| 7 |
undefined |
|
118.0 |
mmHg |
2.0 |
5.29 |
tail cuff plethysmography |
|
0.0 |
unx |
14 |
days |
|
|
101159 |
2581 |
| MW |
systolic blood pressure |
unilateral nephrectomy (for 14 days) then vehicle control condition |
Fogo A, et al., J Clin Invest. 1988 Jul;82(1):322-30. |
arterial blood pressure trait |
male |
days
| 7 |
undefined |
|
118.0 |
mmHg |
2.0 |
5.29 |
tail cuff plethysmography |
|
0.0 |
unx |
42 |
days |
|
|
101163 |
2581 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then sham surgical control condition (for 7 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 5 |
undefined |
|
165.0 |
mmHg |
7.0 |
15.65 |
tail cuff plethysmography |
|
0.0 |
sham acf |
7 |
days |
|
|
101365 |
2585 |
| SS-Nppbem2Mcwi-/- |
systolic blood pressure |
vehicle control condition |
Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. |
arterial blood pressure trait |
male |
252.0 days
| 7 |
|
serial mean |
197.0 |
mmHg |
26.0 |
68.79 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
99832 |
2319 |
| LL/Mav |
systolic blood pressure |
vehicle control condition |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
arterial blood pressure trait |
male |
49.0 days-56.0 days |
13 |
undefined |
|
115.0 |
mmHg |
3.0 |
10.82 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102644 |
2703 |
| SS/NEisSlc |
systolic blood pressure |
controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) |
Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. |
arterial blood pressure trait |
male |
126.0 days
| 8 |
undefined |
|
226.0 |
mmHg |
11.0 |
31.11 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102314 |
2684 |
| SS.ZUC-Leprfa+/+/Slc |
systolic blood pressure |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
arterial blood pressure trait |
female |
91.0 days
| 9 |
undefined |
|
138.0 |
mmHg |
1.0 |
3.0 |
tail cuff plethysmography |
|
0.0 |
ovariectomy |
42 |
days |
|
|
101669 |
2622 |
| SS.ZUC-Leprfa-/-/Slc |
systolic blood pressure |
bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) |
Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. |
arterial blood pressure trait |
female |
91.0 days
| 8 |
undefined |
|
221.0 |
mmHg |
5.0 |
14.14 |
tail cuff plethysmography |
|
0.0 |
ovariectomy |
42 |
days |
|
|
101671 |
2622 |
| LH/Mav |
systolic blood pressure |
vehicle control condition |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
arterial blood pressure trait |
male |
84.0 days
| 8 |
undefined |
|
160.0 |
mmHg |
|
|
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
102849 |
2761 |
| WF/Mol |
systolic blood pressure |
vehicle control condition then sham surgical control condition (for 4 days) |
Wahlander H, et al., Acta Physiol Scand. 1999 Feb;165(2):143-54. |
arterial blood pressure trait |
male |
days
| 5 |
undefined |
|
123.0 |
mmHg |
5.0 |
11.18 |
tail cuff plethysmography |
|
0.0 |
sham acf |
4 |
days |
|
|
101347 |
2585 |
| MWF/FubRkb |
systolic blood pressure |
vehicle control condition (10 mg/kg/d) (for 28 days) |
Gil-Ortega M, etal., Am J Nephrol. 2020 Feb 21:1-10. doi: 10.1159/000506275. |
arterial blood pressure trait |
male |
112.0 days
| 10 |
|
|
151.5 |
mmHg |
9.0 |
28.46 |
tail cuff plethysmography |
|
0.0 |
|
|
|
|
|
109409 |
3140 |
| SHRSP/A3N |
systolic blood pressure |
controlled sodium chloride content drinking water (1 %) (for 84 days) and controlled fat content diet (24.5 %) (for 84 days) and vehicle control condition (for 84 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
arterial blood pressure trait |
male |
168.0 days-189.0 days |
6 |
|
serial mean |
284.0 |
mmHg |
8.0 |
19.6 |
tail cuff plethysmography |
tail |
0.0 |
|
|
|
average 3 week intervals for 12 weeks |
|
107499 |
3090 |