Phenominer Database Results (459 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 191.0 mmHg 3.5 15.65 tail cuff plethysmography 0 average of 4days 65481 611
SS.LEW-(D1Uia8-D1Rat211)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 207.0 mmHg 5.8 25.94 tail cuff plethysmography 0 average of 4days 65485 611
SS.LEW-(D1Mco75-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 182.0 mmHg 3.3 14.76 tail cuff plethysmography 0 average of 4days 65487 611
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 36 and 40 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 66.0 days-70.0 days 20 serial mean 190.0 mmHg 5.4 24.15 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65309 565
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 67.0 days-69.0 days 5 137.8 mmHg 1.6 3.58 intra-aortic abdominal radiotelemetry 86400 65042 283
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 76.0 days-78.0 days 6 169.6 mmHg 2.1 5.14 intra-aortic abdominal radiotelemetry 86400 65045 283
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 114.0 days-116.0 days 3 219.3 mmHg 4.2 7.27 intra-aortic abdominal radiotelemetry 86400 65050 283
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 39 serial mean 191.8 mmHg 2.6 16.24 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65801 237
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6 arterial blood pressure trait male 62.0 days 20 195.0 mmHg 2.7 12.07 tail cuff plethysmography 0 only mentioned blood pressure 65829 633
SHR/NHsd systolic blood pressure controlled sodium content diet (4 %) (for 14 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 67.0 days 10 179.0 mmHg 5.0 15.81 tail cuff plethysmography 0 66118 691
SHR/NHsd systolic blood pressure controlled sodium content diet (4 %) (for 28 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 81.0 days 10 204.0 mmHg 3.9 12.33 tail cuff plethysmography 0 66120 691
SS.LEW-(D3Rat52-D3Rat17)/Ayd systolic blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days) Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8. arterial blood pressure trait male 66.0 days-77.0 days 6 measurement taken every 4 hours during a 24-hour period serial mean 164.0 mmHg 4.0 9.8 radiotelemetry 86400.0 65545 615
SS.LEW-(D3Chm64-D3Rat17)/Ayd systolic blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days) Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8. arterial blood pressure trait male 66.0 days-77.0 days 8 measurement taken every 4 hours during a 24-hour period serial mean 228.0 mmHg 8.0 22.63 radiotelemetry 86400.0 65550 615
SS.LEW-(D3Mco21-D3Rat17)/Ayd systolic blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days) Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8. arterial blood pressure trait male 66.0 days-77.0 days 6 measurement taken every 4 hours during a 24-hour period serial mean 194.0 mmHg 9.0 22.05 radiotelemetry 86400.0 65552 615
SS/JrSeac systolic blood pressure controlled sodium content diet (8 %) (for 35 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 77.0 days 5 246.0 mmHg 10.73 24.0 tail cuff plethysmography 0.0 67249 733
SR/Jr systolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56.0 days-63.0 days 8 serial mean 124.0 mmHg 2.0 5.66 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min daily for a week 11700 119
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56.0 days-63.0 days 8 serial mean 118.0 mmHg 2.0 5.66 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min daily for a week 11708 119
SS/Jr systolic blood pressure controlled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 100.0 days 21 serial mean 244.0 mmHg 6.2 28.41 tail cuff plethysmography 11781 146
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 42 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 79.0 days 20 serial mean 198.1 mmHg 5.7 25.49 tail cuff plethysmography 11790 146
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 11 serial mean 200.9 mmHg 8.2 27.2 tail cuff plethysmography 11793 146
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait female 61.0 days 12 serial mean 215.5 mmHg 8.5 29.44 tail cuff plethysmography 11794 146
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 224.9 mmHg 4.8 21.47 tail cuff plethysmography average of 12 readings from 4 daily sessions 11795 147
SS.SR-(D7Mco7-D7Wox19)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 209.0 mmHg 2.2 9.84 tail cuff plethysmography average of 12 readings from 4 daily sessions 11820 147
SS.MNS-(D10M11Mit119-D10Mit11)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 182.0 mmHg 2.2 9.84 tail cuff plethysmography average of 12 readings from 4 daily sessions 11833 148
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 41 serial mean 205.0 mmHg 2.6 16.65 tail cuff plethysmography average of 12 readings from 4 daily sessions 11841 148
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 130.0 mmHg 4.0 18.33 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11849 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91.0 days-94.0 days 35 continuous mean 206.0 mmHg 6.0 35.5 vascular indwelling catheter method femoral artery 259200.0 3 h per day 11984 229
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 198.0 mmHg 3.96 17.71 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12131 232
SS.MNS-(D10Mco62-D10Mco30)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 180.0 mmHg 2.86 12.79 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12132 232
SS.MNS-(D10Mco30-D10Got91)/1Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 206.0 mmHg 5.06 22.63 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12138 232
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 8 serial mean 140.0 mmHg 4.4 12.45 tail cuff plethysmography tail 0 12175 222
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 197.0 mmHg 3.74 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11907 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 198.0 mmHg 3.62 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11912 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 204.0 mmHg 3.72 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11911 205
SS.LEW-(D10Mco84-D10Mco143)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 194.0 mmHg 4.18 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11917 205
SS.LEW-(D10Mco113-D10Got93)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 199.0 mmHg 2.04 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11915 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 194.0 mmHg 3.38 15.12 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12808 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 30 198.0 mmHg 1.78 9.75 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12810 313
SS.LEW-(D1Mco36-D1Mco77)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 184.0 mmHg 3.07 13.73 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12819 313
SS.LEW-(D1Mco36-D1Mco101)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 30 173.0 mmHg 1.36 7.45 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12821 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 215.0 mmHg 3.72 16.64 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13084 282
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 191.0 mmHg 1.58 7.07 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13085 282
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 231.0 mmHg 3.3 14.76 tail cuff plethysmography average of 3-4 consistent readings 12450 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 222.0 mmHg 3.7 16.55 tail cuff plethysmography average of 3-4 consistent readings 12453 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 235.0 mmHg 4.8 21.47 tail cuff plethysmography average of 3-4 consistent readings 12456 266
SS.LEW-(D1Uia2-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 187.0 mmHg 2.42 10.82 tail cuff plethysmography average of 3-4 consistent readings 12465 266
SS.LEW-(D1Rat196-D1Mco36)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 183.0 mmHg 2.25 10.06 tail cuff plethysmography average of 3-4 consistent readings 12469 266
SS.LEW-(D1Uia8-D1Rat213)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 169.0 mmHg 2.6 11.63 tail cuff plethysmography average of 3-4 consistent readings 12475 266
SHRSP systolic blood pressure controlled sodium content diet (0.4 %) (for 63 days) Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. arterial blood pressure trait female 91.0 days 4 serial mean 200.1 mmHg 9.8 19.6 tail cuff photoplethysmography 0 UR1000; Ueda average of 3 consistent readings 12560 268
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 26 and 27 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-69.0 days 16 157.8 mmHg 3.2 12.8 tail cuff photoplethysmography 172800 12672 283
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 73.0 days-75.0 days 10 211.0 mmHg 2.05 6.48 radiotelemetry 345600 C-40 transmitter (Data Sciences International, St. Paul, MN) aveerage of 4-hour interval averages over 4 days 12915 313
SS.LEW-(D1Mco36-D1Mco101)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 33 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 73.0 days-75.0 days 10 178.0 mmHg 1.56 4.93 radiotelemetry 345600 C-40 transmitter (Data Sciences International, St. Paul, MN) aveerage of 4-hour interval averages over 4 days 12919 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-60.0 days 15 173.5 mmHg 4.0 15.49 tail cuff photoplethysmography 172800 12664 283
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 214.0 mmHg 5.61 25.09 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13018 305
SS.SHR-(D9Mco72-D9Mco93)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 166.0 mmHg 2.57 11.49 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13024 305
SS.LEW-(D10Arb9-D10Mco84)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 186.0 mmHg 3.21 14.36 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13132 282
SS.LEW-(D10Mco84-D10Got93)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 30 serial mean 189.0 mmHg 2.28 12.49 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13136 282
SS.SHR-(D9Mco72-D9Rat89)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 183.0 mmHg 7.72 tail cuff plethysmography 0.0 67510 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 194.0 mmHg 7.36 tail cuff plethysmography 0.0 67509 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 214.0 mmHg 5.26 tail cuff plethysmography 0.0 67515 749
SS.SHR-(D9Mco72-D9Mco109)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 188.0 mmHg 3.21 tail cuff plethysmography 0.0 67514 749
SS.SHR-(D9Mco72-D9Rat55)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 188.0 mmHg 3.67 tail cuff plethysmography 0.0 67512 749
SS.SHR-(D9Rat7-D9Mco91)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 208.0 mmHg 5.78 tail cuff plethysmography 0.0 67525 749
SS.SHR-(D9Rat7-D9Rat52)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 203.0 mmHg 6.11 tail cuff plethysmography 0.0 67526 749
SS.SR-(D13N1-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait not specified 65.0 days-68.0 days 26 data obtained at three consistent sessions per day serial mean 217.0 mmHg tail cuff plethysmography 345600 66029 650
SS.LEW-(D5Mco39-D5Mco57)(D5Mco41-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 205.0 mmHg 5.1 tail cuff plethysmography 0.0 restrained, 28 degrees C 70585 1482
SS.LEW-(D5Mco42-D5Mco47)/1Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 231.0 mmHg 4.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70592 1482
SS.LEW-(D5Mco43-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 179.0 mmHg 3.2 tail cuff plethysmography 0.0 restrained, 28 degrees C 70594 1482
SR/JrHsd systolic blood pressure controlled sodium content diet (8 %) (between 55 and 56 days) Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. arterial blood pressure trait male 139.0 days-140.0 days 5 130.0 mmHg 1.25 2.8 intra-aortic abdominal radiotelemetry 0.0 67854 810
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 18 191.0 mmHg 1.65 7.0 tail cuff plethysmography 0.0 69129 1126
SS/JrHsd systolic blood pressure controlled sodium content diet (8 %) (between 24 and 28 days) Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. arterial blood pressure trait male 108.0 days-112.0 days 8 211.7 mmHg 2.4 6.79 intra-aortic abdominal radiotelemetry 0.0 70501 1458
SS.SR-(rs65785750-rs106808193)/Opaz systolic blood pressure controlled sodium content diet (8 %) (between 24 and 28 days) Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. arterial blood pressure trait female 108.0 days-112.0 days 8 167.9 mmHg 3.2 9.05 intra-aortic abdominal radiotelemetry 0.0 70353 1358
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 93.0 days 21 serial mean 127.2 mmHg 4.1 18.79 vascular indwelling catheter method left femoral artery 10800.0 69515 151
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 146.0 mmHg 1.26 7.0 tail cuff plethysmography 0.0 69173 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 31 197.0 mmHg 1.8 10.0 tail cuff plethysmography 0.0 69176 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 144.0 mmHg 1.98 11.0 tail cuff plethysmography 0.0 69180 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 20 192.0 mmHg 1.57 7.0 tail cuff plethysmography 0.0 69189 1126
SHRSP.SHRSR-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 31 190.0 mmHg 0.9 5.0 tail cuff plethysmography 0.0 69193 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 35 153.0 mmHg 2.03 12.0 tail cuff plethysmography 0.0 69196 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 34 192.0 mmHg 0.79 4.6 tail cuff plethysmography 0.0 69198 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 5 198.0 mmHg 1.34 3.0 tail cuff plethysmography 0.0 69200 1126
WKY.SHR-(D1Mgh14-D1Rat77)/Iwai systolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to ambient light (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126.0 days 8 128.6 mmHg 0.81 2.3 vascular indwelling catheter method left common carotid artery 0.0 daytime (7 AM - 7 PM) 70093 1281
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 20 serial mean 130.0 mmHg 3.5 15.65 vascular indwelling catheter method left femoral artery 0.0 69443 151
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 220.0 mmHg 5.6 tail cuff plethysmography 0.0 restrained, 28 degrees C 70581 1482
SS.LEW-(D1Mco36-D1Rat200)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 226.0 mmHg 4.0 21.91 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96941 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 194.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96981 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 208.0 mmHg 6.0 32.86 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96982 1778
SHR/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 18 undefined 188.0 mmHg 0.94 4.0 tail cuff plethysmography 0.0 97913 1938
SHR-Ndufc2em1Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 10 undefined 183.0 mmHg 0.63 2.0 tail cuff plethysmography 0.0 97917 1938
SHR-Ndufc2em2Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 12 undefined 181.0 mmHg 2.6 9.0 tail cuff plethysmography 0.0 97923 1938
SHR-Ndufc2em2Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 26 undefined 177.0 mmHg 1.37 7.0 tail cuff plethysmography 0.0 97925 1938
SR systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 42.0 days 5 104.0 mmHg 2.68 6.0 tail cuff plethysmography 0.0 103285 2803
SS systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 84.0 days 7 206.0 mmHg 2.27 6.0 tail cuff plethysmography 0.0 103286 2803
SS.BN-(D13Hmgc1048-D13Hmgc1045)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 44.0 days-53.0 days 11 serial mean 117.0 mmHg 2.0 6.63 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-O 98481 2079
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 44.0 days-53.0 days 11 serial mean 122.0 mmHg 2.0 6.63 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-P 98482 2079
SS-Nppbem2Mcwi-/- systolic blood pressure controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58.0 days-67.0 days serial mean 155.0 mmHg 2.0 intra-aortic abdominal radiotelemetry 32400.0 98412 2059
SS-Agtrapem4Mcwi-/- systolic blood pressure controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58.0 days-67.0 days serial mean 139.0 mmHg 2.0 intra-aortic abdominal radiotelemetry 32400.0 98416 2059
SR systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 126.0 days 6 122.0 mmHg 5.31 13.0 tail cuff plethysmography 0.0 103289 2803
SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58.0 days-67.0 days 11 serial mean 152.0 mmHg 4.0 13.27 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-P 98503 2079
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 7 serial mean 213.0 mmHg 2.05 5.42 radiotelemetry 0.0 97982 1958
SS.BN-(D13Got42-D13Hmgc885)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 15 serial mean 171.0 mmHg 5.0 19.36 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-F 98573 2098
SS.BN-(D13Got42-D13Hmgc664)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 5 serial mean 170.0 mmHg 6.0 13.42 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-G 98574 2098
SS.BN-(D13Rat151-D13Rat197)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 14 serial mean 156.0 mmHg 5.0 18.71 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry 98567 2098
SS.SHR-(D9Mco110-D9Got111)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 6 serial mean 178.0 mmHg 4.17 10.21 radiotelemetry 0.0 97954 1958
SS.BN-(D13Rat130-D13Rat32)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 12 serial mean 159.0 mmHg 4.0 13.86 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-K 98578 2098
SS.LEW-(D1Rat211-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 34 and 38 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 73.0 days-80.0 days 8 171.0 mmHg 3.4 9.62 intra-aortic abdominal radiotelemetry 10 average of 24 hr 65498 611
SS.LEW-(D1Mco102-D1Got46)/Mco systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 188.0 mmHg 3.5 15.65 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65308 565
SS.LEW-(D1Mco102-D1Mco129)/1Mco systolic blood pressure controlled sodium content diet (0.4 %) (between 36 and 40 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 66.0 days-70.0 days 20 serial mean 172.0 mmHg 1.9 8.5 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65310 565
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 12 serial mean 160.0 mmHg 6.0 20.78 vascular indwelling catheter method left femoral artery 0 65463 151
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 107.0 days-109.0 days 4 215.6 mmHg 4.1 8.2 intra-aortic abdominal radiotelemetry 86400 65048 283
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 147.0 days-149.0 days 2 228.2 mmHg 3.0 4.24 intra-aortic abdominal radiotelemetry 86400 65054 283
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 114.0 days-116.0 days 4 223.7 mmHg 4.6 9.2 intra-aortic abdominal radiotelemetry 86400 65051 283
SS.SR-(D7Mco19-D7Mco7)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 85.0 days-87.0 days 10 250.5 mmHg 9.8 30.99 tail cuff photoplethysmography 172800 65075 283
SS/Jr systolic blood pressure controlled sodium content diet Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 53.0 days 10 151.0 mmHg 5.1 16.13 tail cuff plethysmography 0 66115 691
SS.SR-(D3Mco36-D3Mco46)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 201.3 mmHg 2.2 13.91 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65796 237
SHR/NHsd systolic blood pressure controlled sodium content diet Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 53.0 days 10 154.0 mmHg 3.3 10.44 tail cuff plethysmography 0 66116 691
SS/JrSeac systolic blood pressure controlled sodium content diet (0.3 %) (for 84 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 126.0 days 5 117.0 mmHg 11.18 25.0 tail cuff plethysmography 0.0 67250 733
SS/JrSeac systolic blood pressure controlled sodium content diet (8 %) (for 84 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 126.0 days 5 249.0 mmHg 18.34 41.0 tail cuff plethysmography 0.0 67251 733
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 218.3 mmHg 2.6 16.44 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65791 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 210.6 mmHg 3.4 15.21 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65792 237
SS.SR-(D7Mco7-D7Rat81)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 228.8 mmHg 2.4 10.73 tail cuff plethysmography average of 12 readings from 4 daily sessions 11808 147
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 19 serial mean 221.8 mmHg 2.9 12.64 tail cuff plethysmography average of 12 readings from 4 daily sessions 11825 147
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 18 serial mean 217.0 mmHg 4.0 16.97 tail cuff plethysmography average of 12 readings from 4 daily sessions 11831 148
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91.0 days-94.0 days 42 continuous mean 127.0 mmHg 3.0 19.44 vascular indwelling catheter method femoral artery 259200.0 3 h per day 12006 229
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 42 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 81.0 days-84.0 days 9 213.0 mmHg 7.47 22.41 intra-aortic abdominal radiotelemetry aorta 345600.0 recorded every 5 minutes for 4 days 12072 205
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 210.0 mmHg 4.6 20.57 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12130 232
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 209.0 mmHg 3.51 15.7 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12128 232
SS.MNS-(D10Mco30-D10Got101)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 190.0 mmHg 2.4 10.73 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12137 232
SS.MNS-(D10Mco30-D10Got91)/2Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 201.0 mmHg 2.71 12.12 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12139 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 10 serial mean 132.0 mmHg 3.1 9.8 tail cuff plethysmography tail 0 12165 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 10 serial mean 150.0 mmHg 2.3 7.27 tail cuff plethysmography tail 0 12169 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 8 serial mean 141.0 mmHg 1.8 5.09 tail cuff plethysmography tail 0 12171 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 8 serial mean 142.0 mmHg 2.6 7.35 tail cuff plethysmography tail 0 12177 222
SS.LEW-(D10Mco84-D10Mco129)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 213.0 mmHg 5.37 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11919 205
SS.LEW-(D1Mco99-D1Rat49)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 197.0 mmHg 3.99 17.84 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12823 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 30 serial mean 206.0 mmHg 2.23 12.21 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13125 282
SS.LEW-(D1Uia8-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 191.0 mmHg 2.24 10.02 tail cuff plethysmography average of 3-4 consistent readings 12471 266
SHRSP systolic blood pressure controlled sodium content diet (0.4 %) (for 63 days) Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. arterial blood pressure trait male 91.0 days 4 serial mean 219.5 mmHg 7.65 15.3 tail cuff photoplethysmography 0 UR1000; Ueda average of 3 consistent readings 12556 268
SHR systolic blood pressure controlled sodium content diet (0.4 %) (for 63 days) Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. arterial blood pressure trait male 91.0 days 4 serial mean 181.8 mmHg 1.75 3.5 tail cuff photoplethysmography 0 UR1000; Ueda average of 3 consistent readings 12582 268
WKY systolic blood pressure controlled sodium content diet (0.4 %) (for 63 days) Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. arterial blood pressure trait male 91.0 days 4 serial mean 131.7 mmHg 2.25 4.5 tail cuff photoplethysmography 0 UR1000; Ueda average of 3 consistent readings 12584 268
WKY systolic blood pressure controlled sodium content diet (0.4 %) (for 63 days) Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. arterial blood pressure trait female 91.0 days 4 serial mean 127.0 mmHg 5.75 11.5 tail cuff photoplethysmography 0 UR1000; Ueda average of 3 consistent readings 12585 268
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 213.0 mmHg 4.85 21.69 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13011 305
SS.SHR-(D9Wox16-D9Mco77)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 209.0 mmHg 3.78 16.9 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13019 305
SS.SHR-(D9Rat7-D9Mco93)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 195.0 mmHg 4.32 19.32 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13025 305
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 35 and 37 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 75.0 days-79.0 days 5 serial mean 185.0 mmHg 1.97 4.41 intra-aortic abdominal radiotelemetry lower abdominal aorta 172800 C-40 transmitter (Data Sciences International, St. Paul, MN) average of 12 4-hour averages over 48 hours using 5 or 6 rats 13026 305
SS.LEW-(D10Arb9-D10Got101)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 217.0 mmHg 4.28 19.14 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13127 282
SS.LEW-(D10Arb9-D10Rat57)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 183.0 mmHg 2.07 9.26 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13129 282
SS.LEW-(D10Rat29-D10Got93)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 184.0 mmHg 3.05 13.64 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13131 282
SS.SHR-(D9Mco72-D9Mco105)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 20 183.0 mmHg 4.15 18.56 tail cuff plethysmography 0.0 67508 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 197.0 mmHg 3.53 tail cuff plethysmography 0.0 67511 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 263.0 mmHg 5.6 tail cuff plethysmography 0.0 67517 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 200.0 mmHg 4.22 tail cuff plethysmography 0.0 67521 749
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 207.0 mmHg 4.7 21.02 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65305 565
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 40 serial mean 216.0 mmHg 2.4 15.18 tail cuff plethysmography tail 0 64736 222
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 46 serial mean 207.0 mmHg 2.2 14.92 tail cuff plethysmography tail 0 64733 222
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 20 serial mean 219.0 mmHg 3.4 15.21 tail cuff plethysmography tail 0 64738 222
SS.SR-(Syt2-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait not specified 65.0 days-68.0 days 25 data obtained at three consistent sessions per day serial mean 219.0 mmHg tail cuff plethysmography 345600 66030 650
SS.LEW-(D5Mco39-D5Mco57)/3Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 184.0 mmHg 4.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70590 1482
SS.LEW-(D5Mco39-D5Mco41)(D5Mco42-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 157.0 mmHg 4.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70595 1482
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 18 185.0 mmHg 1.72 7.3 tail cuff plethysmography 0.0 69127 1126
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 18 199.0 mmHg 0.24 1.0 tail cuff plethysmography 0.0 69130 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 32 199.0 mmHg 1.77 10.0 tail cuff plethysmography 0.0 69169 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 29 202.0 mmHg 1.67 9.0 tail cuff plethysmography 0.0 69170 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 31 176.0 mmHg 1.89 10.5 tail cuff plethysmography 0.0 69174 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 33 164.0 mmHg 2.61 15.0 tail cuff plethysmography 0.0 69187 1126
WKY/NCrl systolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to darkness (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126.0 days 7 131.7 mmHg 0.83 2.2 vascular indwelling catheter method left common carotid artery 0.0 nighttime (7 PM - 7 AM) 70086 1281
WKY.SHR-(D1Mgh14-D1Rat77)/Iwai systolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to darkness (for 12 hours) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126.0 days 8 136.2 mmHg 1.03 2.9 vascular indwelling catheter method left common carotid artery 0.0 nighttime (7 PM - 7 AM) 70094 1281
SS.LEW-(D5Mco39-D5Mco57)/2Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 221.0 mmHg 6.3 tail cuff plethysmography 0.0 restrained, 28 degrees C 70589 1482
SS.LEW-(D5Mco39-D5Mco41)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 190.0 mmHg 5.6 tail cuff plethysmography 0.0 restrained, 28 degrees C 70584 1482
SS.LEW-(D1Mco134-D1Wox6)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 155.0 mmHg 16.0 87.64 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96945 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 226.0 mmHg 4.0 21.91 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96984 1778
SHR-Ndufc2em2Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 16 undefined 186.0 mmHg 1.5 6.0 tail cuff plethysmography 0.0 97927 1938
SS systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 42.0 days 5 113.0 mmHg 2.24 5.0 tail cuff plethysmography 0.0 103284 2803
SR systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 84.0 days 6 115.0 mmHg 4.9 12.0 tail cuff plethysmography 0.0 103287 2803
SS/Hsd systolic blood pressure controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58.0 days-67.0 days serial mean 149.0 mmHg 2.0 intra-aortic abdominal radiotelemetry 32400.0 98417 2059
SR systolic blood pressure controlled sodium content diet (6 %) (between 35 and 49 days) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. arterial blood pressure trait male 77.0 days-91.0 days 7 139.0 mmHg 7.56 20.0 oscillometric sphygmomanometer 0.0 103351 2804
SR systolic blood pressure controlled sodium content diet (6 %) (between 21 and 28 days) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. arterial blood pressure trait male 63.0 days-70.0 days 7 135.0 mmHg 4.91 13.0 oscillometric sphygmomanometer 0.0 103350 2804
SS systolic blood pressure controlled sodium content diet (6 %) (between 56 and 70 days) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. arterial blood pressure trait male 98.0 days-132.0 days 7 234.0 mmHg 15.87 42.0 oscillometric sphygmomanometer 0.0 103355 2804
SS.BN-(D13Hmgc1041-D13Hmgc885)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58.0 days-67.0 days 15 serial mean 181.0 mmHg 5.0 19.36 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-S 98506 2079
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 195.0 mmHg 4.72 21.11 tail cuff volume pressure recording 0.0 97985 1958
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58.0 days-67.0 days 14 serial mean 185.0 mmHg 5.0 18.71 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant 98500 2079
SR/NEisSlc systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. arterial blood pressure trait male 126.0 days 8 undefined 138.0 mmHg 5.0 14.14 tail cuff plethysmography 0.0 102313 2684
SS-Renem1Mcwi-/- systolic blood pressure controlled sodium content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait male 66.0 days-69.0 days 8 serial mean 72.07 mmHg 2.42 6.84 intra-aortic abdominal radiotelemetry 32400.0 98379 2038
SS/JrIpcv systolic blood pressure controlled sodium content diet (0.3 %) Hojn¿ S, et al., Physiol Res. 2005;54(2):201-6. arterial blood pressure trait male  days undefined 159.0 mmHg 3.0 vascular indwelling catheter method 0.0 102396 2688
SS.SHR-(D9Mco110-D9Mco114)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 201.0 mmHg 2.65 11.85 tail cuff volume pressure recording 0.0 97955 1958
SS.BN-(D13Got42-D13Rat61)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 13 serial mean 191.0 mmHg 6.0 21.63 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-A 98568 2098
SS.BN-(D13Got42-D13Hmgc354)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 16 serial mean 183.0 mmHg 6.0 24.0 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-D 98571 2098
SS.BN-(D13Hmgc354-D13Rat32)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 15 serial mean 151.0 mmHg 5.0 19.36 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-J 98577 2098
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 76.0 days-78.0 days 5 157.7 mmHg 2.3 5.14 intra-aortic abdominal radiotelemetry 86400 65046 283
SS.SR-(D3Mco78-D3Got130)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 209.1 mmHg 4.8 21.47 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65799 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 19 serial mean 190.9 mmHg 3.6 15.69 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65800 237
SS.SR-Inha/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Rapp JP, et al., Genomics 1998 Jul 15;51(2):191-6 arterial blood pressure trait male 62.0 days 20 176.0 mmHg 2.6 11.63 tail cuff plethysmography 0 only mentioned blood pressure 65830 633
SS.LEW-(D3Rat52-D3Chm63)/Ayd systolic blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days) Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8. arterial blood pressure trait male 66.0 days-77.0 days 8 measurement taken every 4 hours during a 24-hour period serial mean 173.0 mmHg 8.0 22.63 radiotelemetry 86400.0 65546 615
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 20 222.0 mmHg 5.01 22.41 tail cuff plethysmography 0.0 67311 749
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 213.0 mmHg 2.5 15.81 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65790 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 206.6 mmHg 2.4 10.73 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65793 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 203.6 mmHg 4.2 18.78 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65794 237
SS/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 41 serial mean 204.7 mmHg 2.1 13.45 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65795 237
SR/Jr systolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to darkness St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56.0 days-63.0 days 8 serial mean 128.0 mmHg 2.0 5.66 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min nightly for a week 11699 119
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 20 serial mean 178.0 mmHg 4.3 19.23 tail cuff plethysmography 11788 146
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 42 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 79.0 days 20 serial mean 231.4 mmHg 7.2 32.2 tail cuff plethysmography 11789 146
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 22 serial mean 264.0 mmHg 5.5 25.8 tail cuff plethysmography 11791 146
SS.SR-(D7Rat16-D7Mgh5)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 210.5 mmHg 2.8 12.52 tail cuff plethysmography average of 12 readings from 4 daily sessions 11796 147
SS.SR-(D7Rat16-D7Rat189)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 219.0 mmHg 3.4 15.21 tail cuff plethysmography average of 12 readings from 4 daily sessions 11802 147
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 217.0 mmHg 3.4 16.66 tail cuff plethysmography 11845 150
SS.WKY-(D2N35-Mme)/Mco systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 185.0 mmHg 1.8 8.82 tail cuff plethysmography 11846 150
SS.MNS-(D10M11Mit119-D10Mit11)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 178.0 mmHg 1.9 9.31 tail cuff plethysmography 11847 150
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70.0 days-77.0 days 8 serial mean 127.0 mmHg 1.0 2.83 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min daily for a week 11704 119
SR/Jr systolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to ambient light St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70.0 days-77.0 days 7 serial mean 138.0 mmHg 4.0 10.58 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min daily for a week 11696 119
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202 arterial blood pressure trait male 65.0 days-68.0 days 24 205.8 mmHg 3.91 19.16 tail cuff photoplethysmography tail average of 4 days, 3 to 4 consistent readings each day, IITC 12093 231
SS.WKY-(D2N35-Mme)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202 arterial blood pressure trait male 65.0 days-68.0 days 27 161.9 mmHg 2.45 12.73 tail cuff photoplethysmography tail average of 4 days, 3 to 4 consistent readings each day, IITC 12105 231
SS.MNS-(Adh1-D2Mit5)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202 arterial blood pressure trait male 65.0 days-68.0 days 20 181.1 mmHg 1.9 8.5 tail cuff photoplethysmography tail average of 4 days, 3 to 4 consistent readings each day, IITC 12108 231
SS.MNS-(D10Mco30-D10Got112)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 190.0 mmHg 2.55 11.4 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12135 232
SS.MNS-(D10Mco30-D10Got91)/3Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 193.0 mmHg 3.5 15.65 tail cuff plethysmography tail 345600.0 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12140 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 10 serial mean 156.0 mmHg 4.0 12.65 tail cuff plethysmography tail 0 12170 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 8 serial mean 140.0 mmHg 2.5 7.07 tail cuff plethysmography tail 0 12178 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 10 serial mean 143.0 mmHg 1.9 6.01 tail cuff plethysmography tail 0 11910 222
SS.LEW-(D10Mco84-D10Mco134)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 187.0 mmHg 2.67 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11916 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 195.0 mmHg 3.27 14.62 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12807 313
SS.SHR-(D9Mco72-D9Mco93)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 35 and 37 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 75.0 days-79.0 days 5 serial mean 146.0 mmHg 1.44 3.22 intra-aortic abdominal radiotelemetry lower abdominal aorta 172800 C-40 transmitter (Data Sciences International, St. Paul, MN) average of 12 4-hour averages over 48 hours using 5 or 6 rats 13030 305
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 202.0 mmHg 1.72 7.69 tail cuff plethysmography average of 3-4 consistent readings 12451 266
SS.LEW-(D1Mco2-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 192.0 mmHg 1.47 6.57 tail cuff plethysmography average of 3-4 consistent readings 12460 266
SS.LEW-(D1Rat196-D1Mgh7)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 212.0 mmHg 4.63 20.71 tail cuff plethysmography average of 3-4 consistent readings 12467 266
SHR systolic blood pressure controlled sodium content diet (0.4 %) (for 63 days) Inomata H, et al., Hypertens Res 2005 Mar;28(3):273-81. arterial blood pressure trait female 91.0 days 4 serial mean 152.2 mmHg 6.0 12.0 tail cuff photoplethysmography 0 UR1000; Ueda average of 3 consistent readings 12583 268
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 26 and 27 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-69.0 days 15 160.5 mmHg 2.3 8.91 tail cuff photoplethysmography 172800 12668 283
SS.SR-(D7Mco19-D7Mco7)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 26 and 27 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-69.0 days 14 170.8 mmHg 3.3 12.35 tail cuff photoplethysmography 172800 12678 283
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 16 serial mean 205.0 mmHg 4.91 19.64 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13015 305
SS.SHR-(D9Wox16-D9Mco85)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 14 serial mean 180.0 mmHg 3.71 13.88 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13022 305
SS.SHR-(D9Mco74-D9Rat64)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 175.0 mmHg 3.22 14.4 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13023 305
SS.LEW-(D10Arb9-D10Rat161)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 32 serial mean 192.0 mmHg 2.45 13.86 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13133 282
SS.SHR-(D9Mco72-D9Uia4)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 181.0 mmHg 3.91 tail cuff plethysmography 0.0 67516 749
SS.LEW-(D17Mco3-D17Mco10)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 20 serial mean 210.0 mmHg 3.7 16.55 tail cuff plethysmography tail 0 64742 222
SS/Jr systolic blood pressure controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 131.0 days-134.0 days 21 data obtained at three consistent sessions per day serial mean 244.0 mmHg tail cuff plethysmography 345600 65963 650
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (1 %) (for 60 days) then controlled sodium content diet (0.2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 131.0 days-134.0 days 11 data obtained at three consistent sessions per day serial mean 209.0 mmHg tail cuff plethysmography 345600 65964 650
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 81.0 days-84.0 days 20 data obtained at three consistent sessions per day serial mean 208.0 mmHg tail cuff plethysmography 345600 65973 650
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 24 days) then controlled sodium content diet (4 %) (for 24 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait not specified 65.0 days-68.0 days 27 data obtained at three consistent sessions per day serial mean 211.0 mmHg tail cuff plethysmography 345600 66028 650
WKY/Bbb systolic blood pressure controlled sodium content diet Kreutz R, et al., Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8778-82 arterial blood pressure trait not specified  days 8 124.8 mmHg 1.1 3.1 radiotelemetry 0.0 67196 116
SR/JrHsd systolic blood pressure controlled sodium content diet (8 %) (between 83 and 84 days) Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. arterial blood pressure trait female 167.0 days-168.0 days 5 120.8 mmHg 3.4 7.6 intra-aortic abdominal radiotelemetry 0.0 67858 810
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 18 139.0 mmHg 1.65 7.0 tail cuff plethysmography 0.0 69126 1126
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 205.0 mmHg 3.4 tail cuff plethysmography 0.0 restrained, 28 degrees C 70580 1482
SS.SR-(rs106870553-rs63922710)/Opaz systolic blood pressure controlled sodium content diet (8 %) (between 24 and 28 days) Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. arterial blood pressure trait female 108.0 days-112.0 days 10 187.0 mmHg 3.0 9.49 intra-aortic abdominal radiotelemetry 0.0 70566 1458
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days 16 serial mean 208.0 mmHg 7.6 30.4 vascular indwelling catheter method left femoral artery 10800.0 69510 151
SHRSP/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 151.0 mmHg 1.44 8.0 tail cuff plethysmography 0.0 69162 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 33 148.0 mmHg 3.13 18.0 tail cuff plethysmography 0.0 69166 1126
SHRSP/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 5 201.0 mmHg 8.72 19.5 tail cuff plethysmography 0.0 69164 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 26 197.0 mmHg 4.12 21.0 tail cuff plethysmography 0.0 69171 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 31 206.0 mmHg 1.44 8.0 tail cuff plethysmography 0.0 69177 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 31 208.0 mmHg 1.44 8.0 tail cuff plethysmography 0.0 69178 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 31 191.0 mmHg 0.72 4.0 tail cuff plethysmography 0.0 69182 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 25 201.0 mmHg 1.4 7.0 tail cuff plethysmography 0.0 69185 1126
SHRSP.SHRSR-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 14 days) and controlled sodium content drinking water (1 %) (for 14 days) and controlled potassium content diet (6.3 mg/g) (for 14 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 56.0 days 31 153.0 mmHg 2.16 12.0 tail cuff plethysmography 0.0 69192 1126
SS.SR-(D2Rat352-rs63922710)/Opaz systolic blood pressure controlled sodium content diet (8 %) (between 24 and 28 days) Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. arterial blood pressure trait female 108.0 days-112.0 days 6 168.4 mmHg 2.0 4.9 intra-aortic abdominal radiotelemetry 0.0 70558 1458
SS.LEW-(D1Rat200-D1Mco136)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 212.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96943 1778
SHRSP/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 18 undefined 181.0 mmHg 3.3 14.0 tail cuff plethysmography 0.0 97914 1938
SHR-Ndufc2em1Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 17 undefined 182.0 mmHg 1.7 7.0 tail cuff plethysmography 0.0 97921 1938
SHR-Ndufc2em2Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 12 undefined 181.0 mmHg 0.87 3.0 tail cuff plethysmography 0.0 97922 1938
SHR-Ndufc2em2Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 24 undefined 189.0 mmHg 0.41 2.0 tail cuff plethysmography 0.0 97926 1938
SS-Nppaem4Mcwi-/- systolic blood pressure controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58.0 days-67.0 days serial mean 195.0 mmHg 5.0 intra-aortic abdominal radiotelemetry 32400.0 98413 2059
SR systolic blood pressure controlled sodium content diet (6 %) (between 56 and 70 days) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. arterial blood pressure trait male 98.0 days-132.0 days 7 146.0 mmHg 6.05 16.0 oscillometric sphygmomanometer 0.0 103352 2804
SS.BN-(D13Hmgc1048-D13Hmgc1045)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58.0 days-67.0 days 11 serial mean 152.0 mmHg 4.0 13.27 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-O 98502 2079
SS.BN-(D13Hmgc1041-D13Hmgc664)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58.0 days-67.0 days 13 serial mean 185.0 mmHg 4.0 14.42 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-Q 98504 2079
SS-Renem1Mcwi+/- systolic blood pressure controlled sodium content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait female 66.0 days-69.0 days 8 serial mean 139.28 mmHg 2.25 6.36 intra-aortic abdominal radiotelemetry 32400.0 98385 2038
SR/JrIpcv systolic blood pressure controlled sodium content diet (0.3 %) Hojn¿ S, et al., Physiol Res. 2005;54(2):201-6. arterial blood pressure trait male  days undefined 137.0 mmHg 3.0 vascular indwelling catheter method 0.0 102395 2688
SS.SHR-(D9Mco110-D9Mco121)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 8 serial mean 171.0 mmHg 7.24 20.48 radiotelemetry 0.0 97952 1958
SS.BN-(D13Got42-D13Rat130)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 14 serial mean 182.0 mmHg 4.0 14.97 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-C 98570 2098
SS.BN-(D13Mit5-D13Rat32)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 14 serial mean 210.0 mmHg 11.0 41.16 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-H 98575 2098
SS.BN-(D13Hmgc5885-D13Rat32)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 14 serial mean 196.0 mmHg 6.0 22.45 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-I 98576 2098
SS-Plekha7em4Mcwi-/- systolic blood pressure controlled sodium content diet (8 %) (for 28 days) Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18. arterial blood pressure trait male 91.0 days 10 180.0 mmHg 7.0 22.14 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 105763 3022
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 210.0 mmHg 3.3 14.76 tail cuff plethysmography 0 average of 4days 65479 611
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 202.0 mmHg 4.1 18.34 tail cuff plethysmography 0 average of 4days 65483 611
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 206.0 mmHg 4.2 18.78 tail cuff plethysmography 0 average of 4days 65482 611
SS.LEW-(D1Uia8-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 191.0 mmHg 2.2 9.84 tail cuff plethysmography 0 average of 4days 65484 611
SS.LEW-(D1Mco75-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 193.0 mmHg 4.2 18.78 tail cuff plethysmography 0 average of 4days 65492 611
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 34 and 38 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 73.0 days-80.0 days 8 199.0 mmHg 5.0 14.14 intra-aortic abdominal radiotelemetry 10 average of 24 hr 65493 611
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 67.0 days-69.0 days 6 143.3 mmHg 1.5 3.67 intra-aortic abdominal radiotelemetry 86400 65043 283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 107.0 days-109.0 days 4 196.6 mmHg 3.6 7.2 intra-aortic abdominal radiotelemetry 86400 65049 283
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 147.0 days-149.0 days 1 219.7 mmHg 1.7 1.7 intra-aortic abdominal radiotelemetry 86400 65053 283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 47 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 114.0 days-116.0 days 5 203.8 mmHg 3.7 8.27 intra-aortic abdominal radiotelemetry 86400 65052 283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 79 and 80 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 147.0 days-149.0 days 2 234.4 mmHg 4.1 5.8 intra-aortic abdominal radiotelemetry 86400 65055 283
SS.SR-(D3Mco36-D3Got166)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 40 serial mean 197.5 mmHg 2.5 15.81 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65797 237
SS.SR-(D3Mco36-D3Got159)/Jr systolic blood pressure controlled sodium content diet (0.4 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Lee SJ, et al., Genetics 2006 Dec;174(4):2203-13. arterial blood pressure trait male 64.0 days-72.0 days 20 serial mean 178.6 mmHg 4.0 17.89 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65798 237
SS.LEW-(D3Rat52-D3Rat130)/Ayd systolic blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days) Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8. arterial blood pressure trait male 66.0 days-77.0 days 7 measurement taken every 4 hours during a 24-hour period serial mean 167.0 mmHg 4.0 10.58 radiotelemetry 86400.0 65548 615
SS/JrSeac systolic blood pressure controlled sodium content diet (0.3 %) (for 35 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. arterial blood pressure trait not specified 77.0 days 5 125.0 mmHg 9.84 22.0 tail cuff plethysmography 0.0 67248 733
SR/Jr systolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to darkness St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70.0 days-77.0 days 7 serial mean 144.0 mmHg 4.0 10.58 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min nightly for a week 11695 119
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (8 %) (between 48 and 55 days) then controlled exposure to darkness St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait male 70.0 days-77.0 days 8 serial mean 136.0 mmHg 1.0 2.83 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min nightly for a week 11703 119
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (8 %) (between 62 and 69 days) then controlled exposure to darkness St. Lezin EM, et al., J Clin Invest 1996 Jan 15;97(2):522-7 arterial blood pressure trait female 56.0 days-63.0 days 8 serial mean 122.0 mmHg 2.0 5.66 intra-aortic abdominal radiotelemetry 604800.0 5 s every 5 min nightly for a week 11707 119
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6. arterial blood pressure trait male 61.0 days-65.0 days 20 serial mean 202.7 mmHg 3.7 16.55 tail cuff plethysmography average of 12 readings from 4 sessions 11775 145
SS.SR-(D3Mco19-D3Mco5)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Cicila GT, et al., Mamm Genome 1999 Feb;10(2):112-6. arterial blood pressure trait male 61.0 days-65.0 days 19 serial mean 181.3 mmHg 2.2 9.59 tail cuff plethysmography average of 12 readings from 4 sessions 11776 145
SS.SR-(Cyp11b1)/Jr systolic blood pressure controlled sodium content diet (1 %) (for 30 days) then controlled sodium content diet (0.2 %) (for 40 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 100.0 days 16 serial mean 200.3 mmHg 6.0 24.0 tail cuff plethysmography 11782 146
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 235.1 mmHg 4.6 20.57 tail cuff plethysmography average of 12 readings from 4 daily sessions 11813 147
SS.SR-(D7Uia1-D7Mco7)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 205.0 mmHg 1.8 8.05 tail cuff plethysmography average of 12 readings from 4 daily sessions 11814 147
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 232.7 mmHg 3.2 14.31 tail cuff plethysmography average of 12 readings from 4 daily sessions 11819 147
SS.MNS-(D10Mco10-Aldoc)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 214.0 mmHg 3.6 16.1 tail cuff plethysmography average of 12 readings from 4 daily sessions 11838 148
SS.WKY-(D2N35-Mme),MNS-(D10Mit11-D10M11Mit119)/Mco systolic blood pressure controlled sodium content diet (0.2 %) (between 15 and 18 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Rapp JP, et al., J Clin Invest 1998 Apr 15;101(8):1591-5. arterial blood pressure trait male 70.0 days-76.0 days 24 serial mean 170.0 mmHg 1.4 6.86 tail cuff plethysmography 11848 150
SS.LEW-(D10Mco84-D10Mco134)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 42 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 81.0 days-84.0 days 8 188.0 mmHg 4.27 12.08 intra-aortic abdominal radiotelemetry aorta 345600.0 recorded every 5 minutes for 4 days 12075 205
SS.MNS-(D10Mco62-D10Got99)/Mco systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 197.0 mmHg 3.04 13.6 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12134 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 10 serial mean 141.0 mmHg 3.2 10.12 tail cuff plethysmography tail 0 12166 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 28 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 63.0 days 10 serial mean 150.0 mmHg 3.5 11.07 tail cuff plethysmography tail 0 12167 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 8 serial mean 141.0 mmHg 3.3 9.33 tail cuff plethysmography tail 0 12172 222
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 221.0 mmHg 3.95 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11913 205
SS.LEW-(D10Mco84-D10Rat58)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Hypertension. 2007 arterial blood pressure trait male 64.0 days-66.0 days 236.0 mmHg 4.7 tail cuff plethysmography warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 11918 205
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 203.0 mmHg 2.98 13.33 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12809 313
SS.LEW-(D1Mco36-D1Rat131)/2Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 170.0 mmHg 2.33 10.42 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12818 313
SS.LEW-(D1Mco36-D1Rat131)/1Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 178.0 mmHg 2.22 9.93 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12817 313
SS.LEW-(D1Mco36-D1Rat106)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 30 173.0 mmHg 1.74 9.53 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12820 313
SS.LEW-(D1Mco85-D1Rat49)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Toland EJ, et al., Mamm Genome. 2008 Mar;19(3):209-18. Epub 2008 Mar 7. arterial blood pressure trait male 64.0 days-66.0 days 20 196.0 mmHg 1.93 8.63 tail cuff plethysmography 4 semi- automatic equipment from IITC, Woodland Hills, CA average of 2-3 readings/day over 4 days 12822 313
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 242.0 mmHg 3.7 16.55 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13082 282
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 218.0 mmHg 3.1 13.86 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13083 282
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 189.0 mmHg 2.92 13.06 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13117 282
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 44 serial mean 190.0 mmHg 1.61 10.68 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13116 282
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 209.0 mmHg 2.97 13.28 tail cuff plethysmography average of 3-4 consistent readings 12452 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 209.0 mmHg 3.26 14.58 tail cuff plethysmography average of 3-4 consistent readings 12457 266
SS.LEW-(D1Mco36-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 188.0 mmHg 3.08 13.77 tail cuff plethysmography average of 3-4 consistent readings 12463 266
SS.LEW-(D1Rat35-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 195.0 mmHg 2.87 12.84 tail cuff plethysmography average of 3-4 consistent readings 12462 266
SS.LEW-(D1Mco87-D1Rat71)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 207.0 mmHg 2.87 12.84 tail cuff plethysmography average of 3-4 consistent readings 12461 266
SS.LEW-(D1Uia8-D1Rat124)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 195.0 mmHg 1.7 7.6 tail cuff plethysmography average of 3-4 consistent readings 12473 266
SS.SR-(D7Mco19-D7Mco7)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-60.0 days 14 160.5 mmHg 3.0 11.22 tail cuff photoplethysmography 172800 12676 283
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 207.0 mmHg 4.1 18.34 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13000 305
SS.SHR-(D9Wox16-D9Rat64)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 180.0 mmHg 2.07 9.26 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13001 305
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-60.0 days 15 154.7 mmHg 1.7 6.58 tail cuff photoplethysmography 172800 12666 283
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 203.0 mmHg 4.11 18.38 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13016 305
SS.SHR-(D9Wox16-D9Mco73)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 202.0 mmHg 4.95 22.14 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13020 305
SS.SHR-(D9Mco74-D9Rat64)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 35 and 37 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 75.0 days-79.0 days 5 serial mean 156.0 mmHg 1.73 3.87 intra-aortic abdominal radiotelemetry lower abdominal aorta 172800 C-40 transmitter (Data Sciences International, St. Paul, MN) average of 12 4-hour averages over 48 hours using 5 or 6 rats 13028 305
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 197.0 mmHg 3.85 tail cuff plethysmography 0.0 67513 749
SS.SHR-(D9Mco72-D9Mco106)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 176.0 mmHg 5.24 tail cuff plethysmography 0.0 67520 749
SS.SHR-(D9Rat7-D9Rat84)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 185.0 mmHg 4.84 tail cuff plethysmography 0.0 67522 749
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 19 serial mean 205.0 mmHg 5.9 25.72 tail cuff plethysmography tail 0 64741 222
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 65.0 days-68.0 days 20 data obtained at three consistent sessions per day serial mean 175.0 mmHg tail cuff plethysmography 345600 65968 650
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (4 %) (between 24 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 65.0 days-68.0 days 38 data obtained at three consistent sessions per day serial mean 260.0 mmHg tail cuff plethysmography 345600 65974 650
SS.SR-(D13Mit9-D13Mit1)/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (4 %) (between 24 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 65.0 days-68.0 days 22 data obtained at three consistent sessions per day serial mean 238.0 mmHg tail cuff plethysmography 345600 66027 650
SS.LEW-(D5Mco39-D5Mco57)/1Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 199.0 mmHg 4.2 tail cuff plethysmography 0.0 restrained, 28 degrees C 70588 1482
SS.LEW-(D5Mco39-D5Mco57)(D5Mco43-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 181.0 mmHg 2.5 tail cuff plethysmography 0.0 restrained, 28 degrees C 70587 1482
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 18 191.0 mmHg 3.02 12.8 tail cuff plethysmography 0.0 69128 1126
SHRSR/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 18 188.0 mmHg 2.83 12.0 tail cuff plethysmography 0.0 69131 1126
SS/JrHsd systolic blood pressure controlled sodium content diet (8 %) (between 24 and 28 days) Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. arterial blood pressure trait female 108.0 days-112.0 days 9 194.4 mmHg 6.2 18.6 intra-aortic abdominal radiotelemetry 0.0 70351 1358
SS/NEisSlc systolic blood pressure controlled sodium content diet (8 %) (for 28 days) then controlled sodium content diet (0.3 %) (for 28 days) Kitada K, et al., PLoS One. 2012;7(7):e41896. Epub 2012 Jul 24. arterial blood pressure trait male 98.0 days 10 144.0 mmHg 4.0 12.65 tail cuff plethysmography 0.0 69687 736
SS/NEisSlc systolic blood pressure controlled sodium content diet (8 %) (for 28 days) then adrenalectomy then controlled sodium content diet (0.3 %) (for 28 days) and dexamethasone (20 ug/d) Kitada K, et al., PLoS One. 2012;7(7):e41896. Epub 2012 Jul 24. arterial blood pressure trait male 98.0 days 4 141.0 mmHg 8.0 16.0 tail cuff plethysmography 0.0 69688 736
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days 20 serial mean 140.6 mmHg 4.4 19.68 vascular indwelling catheter method left femoral artery 10800.0 69509 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 93.0 days 11 serial mean 183.0 mmHg 10.0 33.17 vascular indwelling catheter method left femoral artery 10800.0 69516 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 94.0 days 11 serial mean 182.9 mmHg 4.1 13.6 vascular indwelling catheter method left femoral artery 10800.0 69522 151
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 94.0 days 17 serial mean 134.6 mmHg 4.1 16.9 vascular indwelling catheter method left femoral artery 10800.0 69521 151
SHRSP/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 26 187.0 mmHg 2.55 13.0 tail cuff plethysmography 0.0 69163 1126
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 33 192.0 mmHg 1.22 7.0 tail cuff plethysmography 0.0 69168 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 30 195.0 mmHg 1.46 8.0 tail cuff plethysmography 0.0 69183 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 33 186.0 mmHg 1.2 6.9 tail cuff plethysmography 0.0 69188 1126
SHRSP.SHRSR-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 3 195.0 mmHg 2.89 5.0 tail cuff plethysmography 0.0 69190 1126
SHRSP.SHRSR-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 22 200.0 mmHg 0.85 4.0 tail cuff plethysmography 0.0 69194 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 35 188.0 mmHg 2.11 12.5 tail cuff plethysmography 0.0 69197 1126
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 15 serial mean 184.0 mmHg 7.7 29.82 vascular indwelling catheter method left femoral artery 0.0 69444 151
SS.SR-(D2Rat352-rs63922710)/Opaz systolic blood pressure controlled sodium content diet (8 %) (between 24 and 28 days) Herrera VL, et al., PLoS One. 2013 Jul 4;8(7):e67673. doi: 10.1371/journal.pone.0067673. Print 2013. arterial blood pressure trait male 108.0 days-112.0 days 6 180.8 mmHg 3.7 9.06 intra-aortic abdominal radiotelemetry 0.0 70562 1458
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 191.0 mmHg 2.1 tail cuff plethysmography 0.0 restrained, 28 degrees C 70582 1482
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 198.0 mmHg 8.0 43.82 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96920 1778
SS.LEW-(D1Mco36-D1Mco54)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 226.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96940 1778
SS.LEW-(D1Mco55-D1Wox6)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 157.0 mmHg 6.0 32.86 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96944 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 217.0 mmHg 5.0 27.39 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96983 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 198.0 mmHg 2.0 10.95 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96986 1778
SHR/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 18 undefined 180.0 mmHg 0.94 4.0 tail cuff plethysmography 0.0 97911 1938
SHR/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 18 undefined 189.0 mmHg 1.41 6.0 tail cuff plethysmography 0.0 97912 1938
SHRSP/Bbb systolic blood pressure controlled protein content diet (19.7 %) (for 49 days) and controlled potassium content diet (6.3 mg/g) (for 49 days) and controlled sodium content diet (3.7 mg/g) (for 49 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 91.0 days 5 undefined 193.0 mmHg 6.26 14.0 tail cuff plethysmography 0.0 97915 1938
SHR-Ndufc2em1Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 10 undefined 177.0 mmHg 2.21 7.0 tail cuff plethysmography 0.0 97916 1938
SHR-Ndufc2em1Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 10 undefined 188.0 mmHg 0.63 2.0 tail cuff plethysmography 0.0 97918 1938
SHR-Ndufc2em1Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) and controlled sodium content diet (3.7 mg/g) (for 28 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 70.0 days 17 undefined 174.0 mmHg 1.46 6.0 tail cuff plethysmography 0.0 97919 1938
SHR-Ndufc2em2Mcwi+/+ systolic blood pressure controlled protein content diet (19.7 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) and controlled sodium content diet (3.7 mg/g) (for 84 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 126.0 days 12 undefined 190.0 mmHg 0.87 3.0 tail cuff plethysmography 0.0 97924 1938
SS systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. arterial blood pressure trait male 126.0 days 6 197.0 mmHg 6.94 17.0 tail cuff plethysmography 0.0 103288 2803
SS-Mthfrem1Mcwi-/+ systolic blood pressure controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58.0 days-67.0 days serial mean 152.0 mmHg 6.0 intra-aortic abdominal radiotelemetry 32400.0 98415 2059
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 6 serial mean 203.0 mmHg 4.17 10.21 radiotelemetry 0.0 97984 1958
SS.BN-(D13Got45-D13Rat32)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 12 serial mean 165.0 mmHg 5.0 17.32 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-L 98651 2098
SS/NEisSlc systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. arterial blood pressure trait male 126.0 days 8 undefined 226.0 mmHg 11.0 31.11 tail cuff plethysmography 0.0 102314 2684
SS/NEisSlc systolic blood pressure controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. arterial blood pressure trait male 126.0 days 8 undefined 235.0 mmHg 13.0 36.77 tail cuff plethysmography 0.0 102315 2684
SS-Renem1Mcwi+/+ systolic blood pressure controlled sodium content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait male 66.0 days-69.0 days 5 serial mean 153.22 mmHg 1.42 3.18 intra-aortic abdominal radiotelemetry 32400.0 98373 2038
SS.BN-(D13Got42-D13Got45)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 13 serial mean 194.0 mmHg 7.0 25.24 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-B 98569 2098
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 8 serial mean 201.0 mmHg 7.4 20.93 radiotelemetry 0.0 97983 1958
SS-Plekha7em4Mcwi+/+ systolic blood pressure controlled sodium content diet (8 %) (for 28 days) Endres BT, et al., Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12817-22. doi: 10.1073/pnas.1410745111. Epub 2014 Aug 18. arterial blood pressure trait male 91.0 days 10 213.0 mmHg 8.0 25.3 intra-aortic abdominal radiotelemetry via femoral cannulation 0.0 105762 3022
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 216.0 mmHg 5.1 22.81 tail cuff plethysmography 0 average of 4days 65480 611
SS.LEW-(D1Mco8-D1Rat213)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 183.0 mmHg 3.0 13.42 tail cuff plethysmography 0 average of 4days 65486 611
SS.LEW-(D1Rat211-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 180.0 mmHg 2.8 12.52 tail cuff plethysmography 0 average of 4days 65488 611
SS.LEW-(D1Mco4-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 178.0 mmHg 2.3 10.29 tail cuff plethysmography 0 average of 4days 65489 611
SS.LEW-(D1Rat211-D1Rat18)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Joe B, et al., J Hypertens 2003 Nov;21(11):2077-84. arterial blood pressure trait male 63.0 days-70.0 days 20 179.0 mmHg 2.9 12.97 tail cuff plethysmography 0 average of 4days 65490 611
SS.LEW-(D1Mco102-D1Mco129)/2Mco systolic blood pressure controlled sodium content diet (0.4 %) (between 36 and 40 days) Joe B, et al., Hum Mol Genet. 2009 Aug 1;18(15):2825-38. Epub 2009 May 7. arterial blood pressure trait male 66.0 days-70.0 days 20 serial mean 176.0 mmHg 2.2 9.84 tail cuff plethysmography 345600 Rats warmed to 28 degrees C for measurement. 65311 565
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 14 serial mean 110.0 mmHg 3.0 11.22 vascular indwelling catheter method left femoral artery 0 65462 151
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 27 and 28 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 67.0 days-69.0 days 5 181.0 mmHg 3.6 8.05 intra-aortic abdominal radiotelemetry 86400 65041 283
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 9 and 10 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 76.0 days-78.0 days 5 217.9 mmHg 2.1 4.7 intra-aortic abdominal radiotelemetry 86400 65044 283
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 39 and 40 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 107.0 days-109.0 days 3 228.2 mmHg 2.6 4.5 intra-aortic abdominal radiotelemetry 86400 65047 283
SS.SR-(D3Arb14-D3Mco36)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 85.0 days-87.0 days 10 242.6 mmHg 6.2 19.61 tail cuff photoplethysmography 172800 65073 283
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 85.0 days-87.0 days 19 257.2 mmHg 5.1 22.23 tail cuff photoplethysmography 172800 65072 283
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 85.0 days-87.0 days 9 214.9 mmHg 8.9 26.7 tail cuff photoplethysmography 172800 65074 283
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 42 days) Palijan A, et al., Physiol Genomics 2003 Sep 29;15(1):1-8. arterial blood pressure trait male 66.0 days-77.0 days 15 measurement taken every 4 hours during a 24-hour period serial mean 203.0 mmHg 4.0 15.49 radiotelemetry 86400.0 65536 615
SS/Jr systolic blood pressure controlled sodium content diet (4 %) (for 28 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 81.0 days 10 238.0 mmHg 7.0 22.14 tail cuff plethysmography 0 66119 691
SS/Jr systolic blood pressure controlled sodium content diet (4 %) (for 14 days) Garrett MR, et al., Physiol Genomics 2000 Jun 29;3(1):33-8. arterial blood pressure trait male 67.0 days 10 218.0 mmHg 7.8 24.67 tail cuff plethysmography 0 66117 691
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (2 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait male 61.0 days 20 serial mean 199.3 mmHg 7.5 33.54 tail cuff plethysmography 11787 146
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 7 days) then controlled sodium content diet (4 %) (for 24 days) Cicila GT, et al., Mamm Genome 1997 Dec;8(12):896-902. arterial blood pressure trait female 61.0 days 24 serial mean 250.1 mmHg 4.9 24.0 tail cuff plethysmography 11792 146
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 243.4 mmHg 4.0 17.89 tail cuff plethysmography average of 12 readings from 4 daily sessions 11801 147
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 20 serial mean 230.6 mmHg 4.7 21.02 tail cuff plethysmography average of 12 readings from 4 daily sessions 11807 147
SS.SR-(D7Rat16-D7Rat176)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 27 days) Cicila GT, et al., Genomics 2001 Feb 15;72(1):51-60. arterial blood pressure trait male 68.0 days-70.0 days 19 serial mean 223.7 mmHg 4.0 17.44 tail cuff plethysmography average of 12 readings from 4 daily sessions 11826 147
SS.MNS-(D10Mco14-D10Mit11)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 175.0 mmHg 1.7 7.6 tail cuff plethysmography average of 12 readings from 4 daily sessions 11832 148
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 20 serial mean 205.0 mmHg 2.9 12.97 tail cuff plethysmography average of 12 readings from 4 daily sessions 11837 148
SS.MNS-(Aldoc-D10Mco1)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Dukhanina OI, et al., Mamm Genome 1997 Apr;8(4):229-35. arterial blood pressure trait not specified 64.0 days-68.0 days 38 serial mean 210.0 mmHg 2.7 16.64 tail cuff plethysmography average of 12 readings from 4 daily sessions 11842 148
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 197.0 mmHg 7.0 32.08 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11850 151
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 25 and 28 days) Deng AY, et al., Hypertension 1997 Aug;30(2 Pt 1):199-202 arterial blood pressure trait male 65.0 days-68.0 days 21 209.8 mmHg 4.11 18.83 tail cuff photoplethysmography tail average of 4 days, 3 to 4 consistent readings each day, IITC 12099 231
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 204.0 mmHg 2.84 12.7 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12127 232
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (for 24 days) Saad Y, et al., Mamm Genome. 2008 Jan 4 arterial blood pressure trait male 64.0 days-68.0 days 20 195.0 mmHg 3.35 14.98 tail cuff plethysmography tail 345600 warm up to 28 C Average of 3-4 consistent measurements taken each day over 4 consecutive days 12129 232
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 10 serial mean 142.0 mmHg 2.2 6.96 tail cuff plethysmography tail 0 12164 222
SR/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 10 serial mean 159.0 mmHg 2.0 6.32 tail cuff plethysmography tail 0 12168 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 168 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 203.0 days 8 serial mean 131.0 mmHg 3.3 9.33 tail cuff plethysmography tail 0 12174 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 112 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 147.0 days 8 serial mean 135.0 mmHg 5.1 14.42 tail cuff plethysmography tail 0 12173 222
LEW/NCrl systolic blood pressure controlled sodium content diet (0.2 %) (for 5 days) then controlled sodium content diet (8 %) (for 56 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait male 91.0 days 8 serial mean 152.0 mmHg 4.5 12.73 tail cuff plethysmography tail 0 12176 222
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 196.0 mmHg 2.53 11.31 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13119 282
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 221.0 mmHg 3.44 15.38 tail cuff plethysmography average of 3-4 consistent readings 12454 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 218.0 mmHg 3.83 17.13 tail cuff plethysmography average of 3-4 consistent readings 12455 266
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 191.0 mmHg 3.48 15.56 tail cuff plethysmography average of 3-4 consistent readings 12459 266
SS.LEW-(D1Mco38-D1Rat49)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 181.0 mmHg 3.03 13.55 tail cuff plethysmography average of 3-4 consistent readings 12464 266
SS.LEW-(D1Uia8-D1Mco38)/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Physiol Genomics 2001 Jan 19;4(3):201-14. arterial blood pressure trait male 64.0 days-70.0 days 20 205.0 mmHg 1.76 7.87 tail cuff plethysmography average of 3-4 consistent readings 12470 266
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 17 and 18 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-60.0 days 16 152.7 mmHg 2.6 10.4 tail cuff photoplethysmography 172800 12670 283
SS/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 213.0 mmHg 4.63 20.71 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13013 305
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 26 and 27 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. arterial blood pressure trait male 42.0 days-69.0 days 15 181.9 mmHg 4.1 15.88 tail cuff photoplethysmography 172800 12665 283
SS.SHR-(D9Wox16-D9Rat76)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 204.0 mmHg 3.88 17.35 tail cuff photoplethysmography tail 345600 28 degrees C average of 3 averaged readings per day over 4 days 13021 305
SS.SHR-(D9Wox16-D9Rat64)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 35 and 37 days) Toland EJ, et al., J Hypertens. 2008 Nov;26(11):2134-41. arterial blood pressure trait male 75.0 days-79.0 days 5 serial mean 147.0 mmHg 1.56 3.49 intra-aortic abdominal radiotelemetry lower abdominal aorta 172800 C-40 transmitter (Data Sciences International, St. Paul, MN) average of 12 4-hour averages over 48 hours using 5 or 6 rats 13027 305
SS.LEW-(D10Rat29-D10Mco88)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 191.0 mmHg 4.07 18.2 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13135 282
SS.LEW-(D10Mco89-D10Got101)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 24 and 28 days) Saad Y, et al., Genomics. 2007 Mar;89(3):343-53. Epub 2007 Jan 10. arterial blood pressure trait male 64.0 days-70.0 days 20 serial mean 192.0 mmHg 3.89 17.4 tail cuff photoplethysmography tail 345600 average of 4 daily averages of 3-4 measurements/day 13134 282
SS.SHR-(D9Mco72-D9Mco105)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 207.0 mmHg 3.5 tail cuff plethysmography 0.0 67518 749
SS/Jr systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 213.0 mmHg 5.14 tail cuff plethysmography 0.0 67524 749
SS.SHR-(D9Rat7-D9Got111)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Kumarasamy S, et al., Hypertens Res. 2011 Dec;34(12):1263-70. doi: 10.1038/hr.2011.116. Epub 2011 Aug 4. arterial blood pressure trait not specified 65.0 days-70.0 days 183.0 mmHg 4.14 tail cuff plethysmography 0.0 67523 749
SS/JrTol systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 196.0 mmHg 6.8 tail cuff plethysmography 0.0 restrained, 28 degrees C 70583 1482
SS.LEW-(D1Mco36-D1Mco61)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 227.0 mmHg 7.0 38.34 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96942 1778
SS.LEW-(D1Mco36-D1Mco101)/Mco systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 28 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 173.0 mmHg 1.0 5.48 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96985 1778
SS/JrTol systolic blood pressure controlled sodium content diet (0.3 %) (between 10 and 12 days) and housing in pairs (between 26 and 66 days) then controlled sodium content diet (2 %) (for 24 days) Mell B, et al., Hypertens Res. 2015 Jan;38(1):61-7. doi: 10.1038/hr.2014.134. Epub 2014 Sep 18. arterial blood pressure trait male 64.0 days-66.0 days 30 continuous mean 198.0 mmHg 8.0 43.82 tail cuff plethysmography 0.0 restrained, 28 degrees C average of 2-3 readings/day over 4 days 96980 1778
SHR-Ndufc2em1Mcwi-/+ systolic blood pressure controlled protein content diet (19.7 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) and controlled sodium content diet (3.7 mg/g) (for 56 days) Rubattu S, et al., J Am Heart Assoc. 2016 Feb 17;5(2). pii: e002701. doi: 10.1161/JAHA.115.002701. arterial blood pressure trait not specified 98.0 days 17 undefined 178.0 mmHg 1.46 6.0 tail cuff plethysmography 0.0 97920 1938
SS.LEW-(D1Mco2-D1Mco35)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 39 serial mean 181.0 mmHg 1.3 8.12 tail cuff plethysmography tail 0 64734 222
SS.LEW-(D5Mit9-D5Mco10)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 40 serial mean 201.0 mmHg 2.0 12.65 tail cuff plethysmography tail 0 64737 222
SS.LEW-(D10Mit10-D10Mgh1)/Jr systolic blood pressure controlled sodium content diet (2 %) (between 24 and 27 days) Garrett MR, et al., Genome Res 1998 Jul;8(7):711-23 arterial blood pressure trait not specified 64.0 days-71.0 days 20 serial mean 177.0 mmHg 2.1 9.39 tail cuff plethysmography tail 0 64740 222
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 25 and 28 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait both 65.0 days-68.0 days 20 data obtained at three consistent sessions per day serial mean 199.0 mmHg tail cuff plethysmography 345600 65967 650
SS/Jr systolic blood pressure controlled sodium content diet (0.2 %) (for 10 days) then controlled sodium content diet (2 %) (between 41 and 44 days) Zhang QY, et al., Mamm Genome 1997 Sep;8(9):636-41 arterial blood pressure trait male 81.0 days-84.0 days 20 data obtained at three consistent sessions per day serial mean 231.0 mmHg tail cuff plethysmography 345600 65971 650
WKY.SHRSP-(Asgr1-Vamp2)/Bbb systolic blood pressure controlled sodium content diet Kreutz R, et al., Proc Natl Acad Sci U S A 1995 Sep 12;92(19):8778-82 arterial blood pressure trait not specified  days 9 131.4 mmHg 1.27 3.8 radiotelemetry 0.0 67197 116
SS.LEW-(D5Mco39-D5Mco57)(D5Mco42-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 226.0 mmHg 5.5 tail cuff plethysmography 0.0 restrained, 28 degrees C 70586 1482
SS.LEW-(D5Mco41-D5Mco47)/Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 204.0 mmHg 5.4 tail cuff plethysmography 0.0 restrained, 28 degrees C 70591 1482
SS.LEW-(D5Mco42-D5Mco47)/2Mco systolic blood pressure controlled sodium content diet (2 %) (between 24 and 28 days) Pillai R, et al., Physiol Genomics. 2013 Aug 15;45(16):729-36. doi: 10.1152/physiolgenomics.00077.2013. Epub 2013 Jun 11. arterial blood pressure trait male 62.0 days-66.0 days 187.0 mmHg 5.2 tail cuff plethysmography 0.0 restrained, 28 degrees C 70593 1482
SS/JrHsd systolic blood pressure controlled sodium content diet (8 %) (between 55 and 56 days) Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. arterial blood pressure trait male 139.0 days-140.0 days 6 220.0 mmHg 7.1 17.4 intra-aortic abdominal radiotelemetry 0.0 67851 810
SS/JrHsd systolic blood pressure controlled sodium content diet (8 %) (between 83 and 84 days) Herrera VL, et al., Physiol Genomics. 2006 Aug 16;26(3):172-9. Epub 2006 May 23. arterial blood pressure trait female 167.0 days-168.0 days 8 199.5 mmHg 6.93 19.6 intra-aortic abdominal radiotelemetry 0.0 67857 810
SS.SR-(rs65785750-rs13452155)/Opaz systolic blood pressure controlled sodium content diet (8 %) (between 24 and 28 days) Herrera VL, et al., PLoS One. 2012;7(7):e42214. doi: 10.1371/journal.pone.0042214. Epub 2012 Jul 30. arterial blood pressure trait female 108.0 days-112.0 days 10 185.9 mmHg 3.8 12.02 intra-aortic abdominal radiotelemetry 0.0 70352 1358
SHRSR.SHRSP-(Klk1-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 33 174.0 mmHg 3.31 19.0 tail cuff plethysmography 0.0 69167 1126
SHRSR.SHRSP-(Klk1-D1Mit3)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 42 days) and controlled sodium content drinking water (1 %) (for 42 days) and controlled potassium content diet (6.3 mg/g) (for 42 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 84.0 days 31 181.0 mmHg 1.65 9.2 tail cuff plethysmography 0.0 69175 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 28 days) and controlled sodium content drinking water (1 %) (for 28 days) and controlled potassium content diet (6.3 mg/g) (for 28 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 70.0 days 31 166.0 mmHg 1.96 10.9 tail cuff plethysmography 0.0 69181 1126
SHRSR.SHRSP-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 70 days) and controlled sodium content drinking water (1 %) (for 70 days) and controlled potassium content diet (6.3 mg/g) (for 70 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 112.0 days 28 199.0 mmHg 1.89 10.0 tail cuff plethysmography 0.0 69184 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and controlled potassium content diet (6.3 mg/g) (for 56 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 98.0 days 14 192.0 mmHg 1.6 6.0 tail cuff plethysmography 0.0 69199 1126
SHRSP.SHRSR-(D1Rat134-Mt1-ps1)/Bbb systolic blood pressure controlled sodium content diet (3.7 mg/g) (for 84 days) and controlled sodium content drinking water (1 %) (for 84 days) and controlled potassium content diet (6.3 mg/g) (for 84 days) Rubattu S, et al., Physiol Genomics. 2006 Oct 11;27(2):108-13. Epub 2006 Jul 11. arterial blood pressure trait not specified 126.0 days 1 193.0 mmHg tail cuff plethysmography 0.0 69201 1126
WKY/NCrl systolic blood pressure controlled sodium content diet (8 %) (for 14 days) then controlled exposure to ambient light (for 14 days) Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. arterial blood pressure trait male 126.0 days 7 126.4 mmHg 1.06 2.8 vascular indwelling catheter method left common carotid artery 0.0 daytime (7 AM - 7 PM) 70085 1281
SS.BN-(D13Hmgc1041-D13Hmgc664)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 44.0 days-53.0 days 13 serial mean 121.0 mmHg 1.0 3.61 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-Q 98483 2079
SS-Clcn6em2Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 10 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. arterial blood pressure trait male 58.0 days-67.0 days serial mean 149.0 mmHg 2.0 intra-aortic abdominal radiotelemetry 32400.0 98414 2059
SS systolic blood pressure controlled sodium content diet (6 %) (between 35 and 49 days) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. arterial blood pressure trait male 77.0 days-91.0 days 7 226.0 mmHg 10.21 27.0 oscillometric sphygmomanometer 0.0 103354 2804
SS systolic blood pressure controlled sodium content diet (6 %) (between 21 and 28 days) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. arterial blood pressure trait male 63.0 days-70.0 days 7 208.0 mmHg 15.5 41.0 oscillometric sphygmomanometer 0.0 103353 2804
SS.BN-(D13Hmgc1048-D13Hmgc664)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58.0 days-67.0 days 15 serial mean 153.0 mmHg 4.0 15.49 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 carotid a. to thoracic aorta implant strain 26-N 98501 2079
SS-Renem1Mcwi+/+ systolic blood pressure controlled sodium content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait female 66.0 days-69.0 days 7 serial mean 138.76 mmHg 4.52 11.96 intra-aortic abdominal radiotelemetry 32400.0 98382 2038
SS-Renem1Mcwi-/- systolic blood pressure controlled sodium content diet (0.4 %) (between 66 and 69 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. arterial blood pressure trait male 66.0 days-69.0 days 4 serial mean 76.38 mmHg 2.94 5.88 intra-aortic abdominal radiotelemetry 32400.0 98388 2038
SS.BN-(D13Got42-D13Hmgc497)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 7 serial mean 150.0 mmHg 6.0 15.87 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-E 98572 2098
SS.BN-(D13Got45-D13Hmgc664)/Mcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 14 serial mean 156.0 mmHg 3.0 11.22 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry strain 26-M 98579 2098
SS.SHR-(D9Mco115-D9Mco124)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 6 serial mean 193.0 mmHg 11.25 27.56 radiotelemetry 0.0 97956 1958
SS.SHR-(D9Mco110-D9Mco124)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 7 serial mean 157.0 mmHg 0.82 2.17 radiotelemetry 0.0 97951 1958
SS.SHR-(D9Mco113-D9Mco124)/Bj systolic blood pressure controlled sodium content diet (0.3 %) (for 12 days) then controlled sodium content diet (2 %) (for 24 days) Nie Y, et al., Physiol Genomics. 2016 Jun;48(6):409-19. doi: 10.1152/physiolgenomics.00004.2016. Epub 2016 Apr 25. arterial blood pressure trait male 68.0 days-70.0 days 6 serial mean 164.0 mmHg 5.22 12.79 radiotelemetry 0.0 97953 1958
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60.0 days-67.0 days 12 serial mean 204.0 mmHg 4.0 13.86 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 intra-carotid radiotelemetry 98566 2098