Phenominer Database Results (379 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Individual Records Method Method Duration Post Insult Time Value Experiment Notes Record ID Study ID
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 431.68 beats/min 10.13 30.4 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18107 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 430.66 beats/min 12.88 38.63 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18110 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 413.33 beats/min 15.97 45.17 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18754 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 463.94 beats/min 9.59 19.19 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18758 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 424.61 beats/min 10.82 28.62 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18760 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 431.15 beats/min 29.19 71.49 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18759 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 434.17 beats/min 16.01 45.28 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17482 381
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 425.92 beats/min 18.65 52.74 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17489 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 447.79 beats/min 11.25 22.51 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17492 381
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 403.88 beats/min 17.75 68.76 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17504 381
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 443.8 beats/min 11.46 34.39 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17502 381
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 369.86 beats/min 16.67 23.57 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17501 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 418.72 beats/min 12.0 36.0 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17512 381
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 406.64 beats/min 9.8 21.92 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17515 381
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 388.29 beats/min 19.22 54.36 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17519 381
SS-Chr YBN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 18 413.66 beats/min 11.85 50.27 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17526 381
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 15 425.56 beats/min 14.49 56.12 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17531 381
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 372.01 beats/min 20.08 49.18 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17530 381
FHH-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 392.32 beats/min 63.41 89.68 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17535 381
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 465.07 beats/min 23.98 53.62 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17539 381
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 408.35 beats/min Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17542 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 226.69 beats/min 13.62 49.11 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17547 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 273.08 beats/min 29.68 93.86 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17548 381
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 467.14 beats/min 24.71 65.38 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17552 381
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 349.14 beats/min 30.12 85.19 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49848 461
LE/BluGill heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 254.68 beats/min 9.34 28.01 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49981 461
LEW/Crl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 261.01 beats/min 18.47 52.24 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46506 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 294.78 beats/min 8.27 27.42 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46511 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 317.09 beats/min 22.83 64.57 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46517 461
FHH-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 200.32 beats/min 12.22 36.65 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47569 461
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 16 253.98 beats/min 15.59 62.35 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47579 461
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 235.52 beats/min 6.29 18.86 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47587 461
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 246.83 beats/min 12.12 36.37 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47592 461
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 265.22 beats/min 8.38 25.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47596 461
FHH-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 254.35 beats/min 4.66 14.74 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47600 461
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 209.89 beats/min 13.97 44.19 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47605 461
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 241.58 beats/min 8.76 27.71 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47608 461
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 223.66 beats/min 14.03 39.68 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47610 461
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 261.98 beats/min 5.75 18.18 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47624 461
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 17 243.5 beats/min 4.85 20.01 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47628 461
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 18 249.24 beats/min 4.69 19.89 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47625 461
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 257.14 beats/min 8.39 25.17 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47637 461
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 230.15 beats/min 11.93 37.74 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47638 461
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 221.9 beats/min 10.39 32.86 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47641 461
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 22 259.99 beats/min 6.46 30.28 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47643 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 50 235.28 beats/min 4.68 33.06 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47644 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 17 285.02 beats/min 10.4 42.89 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47653 461
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 14 350.04 beats/min 18.22 68.19 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16121 381
LEW/Crl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 372.75 beats/min 13.56 54.23 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16123 381
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 417.18 beats/min 29.61 88.83 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16126 381
LE/BluGill heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 370.38 beats/min 12.06 36.18 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16127 381
LE/BluGill heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 376.9 beats/min 12.54 37.63 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16131 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 6 213.38 beats/min 14.04 34.38 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45076 461
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 259.58 beats/min 49.97 158.03 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45139 461
FHH-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 180.28 beats/min 12.05 34.07 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45147 461
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 215.48 beats/min 6.6 28.78 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45150 461
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 17 226.19 beats/min 6.24 25.74 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45155 461
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 204.61 beats/min 5.58 17.65 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45167 461
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 223.08 beats/min 5.09 16.11 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45174 461
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 216.61 beats/min 8.02 24.07 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45172 461
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 211.56 beats/min 12.91 38.72 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45177 461
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 18 255.2 beats/min 15.17 64.36 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45184 461
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 274.3 beats/min 50.0 149.99 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45188 461
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 222.91 beats/min 9.81 29.44 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45190 461
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 344.37 beats/min 74.76 247.96 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45193 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 147.04 beats/min 20.23 63.96 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45192 461
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 312.71 beats/min 57.23 180.97 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45197 461
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 17 215.43 beats/min 14.01 57.77 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45194 461
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 20 225.81 beats/min 17.84 79.76 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45198 461
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 206.6 beats/min 10.31 30.94 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45204 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 43 223.63 beats/min 17.45 114.41 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45210 461
FHH-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 6 149.85 beats/min 16.91 41.42 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45211 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 89 209.31 beats/min 4.76 44.94 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45214 461
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 240.05 beats/min 18.91 82.45 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45222 461
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 199.74 beats/min 14.67 46.38 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45224 461
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 23 227.28 beats/min 6.69 32.07 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45226 461
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 218.33 beats/min 14.92 49.5 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45227 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 11 238.15 beats/min 15.05 49.92 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45249 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 383.18 beats/min 58.34 154.35 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45252 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 189.11 beats/min 10.37 31.11 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45254 461
Crlj:WI heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 6 351.0 beats/min 19.0 46.54 vascular transducer tipped catheter 0.0 103043 2784
Crlj:WI heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) and meclofenamate (3 mg/kg) (for 0.5 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 287.0 beats/min 7.0 18.52 vascular transducer tipped catheter 0.0 103048 2784
GK heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) and meclofenamate (3 mg/kg) (for 0.5 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 344.0 beats/min 11.0 29.1 vascular transducer tipped catheter 0.0 103050 2784
Crlj:WI heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) and meclofenamate (3 mg/kg) (for 0.5 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 6 275.0 beats/min 8.0 19.6 vascular transducer tipped catheter 0.0 103051 2784
Crlj:WI heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) and meclofenamate (3 mg/kg) (for 0.5 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 264.0 beats/min 9.0 23.81 vascular transducer tipped catheter 0.0 103052 2784
Hsd:SD heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 427.86 beats/min 13.06 41.31 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15755 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 409.01 beats/min 5.21 12.75 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18104 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 366.99 beats/min 23.28 46.55 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18111 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 416.79 beats/min 8.48 22.45 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18761 381
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 17 411.57 beats/min 13.0 53.6 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17475 381
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 13 418.29 beats/min 10.03 36.15 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17480 381
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 436.17 beats/min 14.55 38.49 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17479 381
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 396.78 beats/min 5.64 16.93 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17484 381
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 425.96 beats/min 24.66 73.99 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17493 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 429.6 beats/min 6.58 13.17 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17498 381
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 434.94 beats/min 9.88 31.24 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17505 381
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 397.64 beats/min 9.71 19.43 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17508 381
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 411.84 beats/min 36.75 97.23 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17511 381
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 443.27 beats/min 22.66 45.31 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17510 381
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 396.11 beats/min 19.99 59.98 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17517 381
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 368.52 beats/min 21.37 56.55 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17520 381
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 417.99 beats/min 12.93 36.58 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17525 381
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 350.62 beats/min 18.91 50.03 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17523 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 399.04 beats/min 15.76 56.81 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17528 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 61 412.19 beats/min 6.25 48.79 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17529 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 400.39 beats/min 11.33 37.57 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17532 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 452.93 beats/min 8.97 28.36 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17534 381
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 412.88 beats/min 24.38 77.08 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17544 381
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 428.88 beats/min 19.96 34.57 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17550 381
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 257.17 beats/min 13.09 41.4 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49972 461
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 183.92 beats/min 12.88 36.42 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46499 461
LEW/Crl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 213.87 beats/min 14.27 45.13 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46500 461
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 244.42 beats/min 21.66 68.5 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46502 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 6 320.02 beats/min 37.3 91.36 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46516 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 11 345.9 beats/min 20.97 69.54 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46513 461
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 12 240.81 beats/min 10.48 36.32 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47573 461
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 253.0 beats/min 10.05 30.16 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47577 461
FHH-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 212.35 beats/min 14.27 40.37 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47574 461
FHH-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 228.85 beats/min 11.81 35.43 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47581 461
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 251.79 beats/min 5.92 15.67 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47583 461
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 23 263.21 beats/min 6.03 28.9 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47584 461
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 25 285.22 beats/min 6.48 32.39 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47593 461
FHH-Chr YBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 245.52 beats/min 5.91 19.62 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47595 461
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 278.29 beats/min 12.74 40.29 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47597 461
FHH-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 244.54 beats/min 8.59 24.29 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47598 461
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 276.33 beats/min 8.47 31.7 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47599 461
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 17 262.63 beats/min 6.79 28.02 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47614 461
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 197.99 beats/min 17.55 49.65 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47621 461
FHH-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 213.22 beats/min 17.47 49.41 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47623 461
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 19 273.59 beats/min 10.1 44.04 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47618 461
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 255.1 beats/min 12.21 40.5 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47627 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 25 262.08 beats/min 5.45 27.27 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47636 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 21 258.48 beats/min 6.69 30.65 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47639 461
FHH-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 204.56 beats/min 15.67 44.33 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47645 461
LEW/Crl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 349.17 beats/min 11.05 44.2 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16128 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 5 234.91 beats/min 11.76 26.29 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45871 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 1 187.41 beats/min Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45077 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 5 184.12 beats/min 23.58 52.73 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45078 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 5 225.17 beats/min 14.97 33.48 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45080 461
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 187.87 beats/min 11.71 35.13 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45143 461
FHH-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 4 173.36 beats/min 23.58 47.17 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45141 461
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 12 200.73 beats/min 27.04 93.68 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45145 461
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 243.51 beats/min 26.83 80.49 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45142 461
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 221.71 beats/min 17.32 51.97 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45158 461
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 22 263.86 beats/min 24.54 115.11 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45159 461
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 292.76 beats/min 77.04 203.82 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45162 461
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 17 208.04 beats/min 9.84 40.59 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45160 461
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 227.39 beats/min 5.69 18.0 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45169 461
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 174.67 beats/min 14.84 46.94 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45171 461
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 197.99 beats/min 5.97 16.89 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45173 461
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 17 182.57 beats/min 26.06 107.47 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45182 461
FHH-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 6 204.34 beats/min 11.08 27.13 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45189 461
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 6 159.17 beats/min 15.56 38.11 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45187 461
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 226.75 beats/min 17.53 76.41 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45191 461
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 228.17 beats/min 8.63 24.42 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45203 461
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 272.88 beats/min 47.09 133.19 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45206 461
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 217.37 beats/min 7.26 21.78 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45216 461
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 17 236.38 beats/min 10.86 44.78 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45218 461
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 210.62 beats/min 11.76 37.17 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45229 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 306.93 beats/min 30.38 80.38 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45248 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 284.37 beats/min 31.65 89.53 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45253 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 256.64 beats/min 31.76 89.83 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45251 461
Crlj:WI heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 415.0 beats/min 10.0 26.46 vascular transducer tipped catheter 0.0 103036 2784
Crlj:WI heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 379.0 beats/min 9.0 23.81 vascular transducer tipped catheter 0.0 103042 2784
Crlj:WI heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) then meclofenamate (3 mg/kg) (for 0.5 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 6 288.0 beats/min 11.0 26.94 vascular transducer tipped catheter 0.0 103047 2784
GK heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) and meclofenamate (3 mg/kg) (for 0.5 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 5 252.0 beats/min 25.0 55.9 vascular transducer tipped catheter 0.0 103053 2784
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 467.49 beats/min 17.12 41.93 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18100 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 441.62 beats/min 9.52 25.2 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18105 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 349.4 beats/min 28.52 57.04 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18108 381
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 423.86 beats/min 17.23 48.72 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17481 381
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 309.1 beats/min Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17483 381
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 421.09 beats/min 14.92 49.48 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17486 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 402.69 beats/min 19.15 50.67 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17495 381
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 356.59 beats/min 14.44 28.88 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17494 381
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 438.83 beats/min 28.19 84.58 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17499 381
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 394.45 beats/min 17.93 50.71 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17503 381
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 400.21 beats/min 26.78 59.88 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17509 381
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 358.54 beats/min 27.09 60.58 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17516 381
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 399.15 beats/min 15.47 51.32 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17521 381
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 380.7 beats/min 11.99 37.92 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17518 381
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 448.23 beats/min 13.23 34.99 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17533 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 393.79 beats/min 12.81 40.52 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17537 381
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 412.26 beats/min 10.5 27.77 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17549 381
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 451.08 beats/min 16.57 57.41 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17551 381
LEW/Crl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 242.22 beats/min 5.72 17.17 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49971 461
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 237.54 beats/min 7.97 23.9 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49970 461
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 250.69 beats/min 6.17 19.5 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49974 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 306.3 beats/min 21.43 37.12 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49975 461
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 205.68 beats/min 16.08 50.83 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49978 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 3 261.19 beats/min 14.7 25.46 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46504 461
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 199.17 beats/min 23.44 74.12 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46507 461
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 200.77 beats/min 14.47 43.4 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46509 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 6 271.62 beats/min 13.53 33.14 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46514 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 14 255.94 beats/min 9.61 35.95 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47568 461
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 236.68 beats/min 6.05 20.07 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47570 461
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 269.09 beats/min 10.68 33.78 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47585 461
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 21 251.89 beats/min 7.46 34.17 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47589 461
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 245.4 beats/min 4.61 13.83 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47591 461
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 262.16 beats/min 7.61 22.83 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47602 461
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 276.05 beats/min 7.51 23.76 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47603 461
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 241.02 beats/min 10.44 33.03 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47607 461
FHH-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 241.65 beats/min 7.55 23.89 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47612 461
FHH-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 4 212.65 beats/min 17.6 35.21 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47613 461
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 18 262.32 beats/min 10.54 44.72 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47619 461
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 258.52 beats/min 6.48 20.5 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47622 461
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 20 252.87 beats/min 5.26 23.51 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47632 461
FHH-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 5 221.87 beats/min 11.62 25.99 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47635 461
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 245.92 beats/min 10.87 32.62 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47640 461
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 25 252.09 beats/min 7.11 35.54 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47646 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 94 255.87 beats/min 4.57 44.3 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47648 461
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 250.34 beats/min 6.48 20.48 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47650 461
SS-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 256.02 beats/min 17.02 51.06 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47651 461
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 230.78 beats/min 7.28 23.02 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47654 461
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 244.32 beats/min 6.26 17.71 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47655 461
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 24 247.22 beats/min 10.24 50.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47659 461
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 389.59 beats/min 19.9 52.64 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16124 381
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 407.25 beats/min 7.98 26.46 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16130 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 287.03 beats/min 8.89 25.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45869 461
FHH-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 155.46 beats/min 14.13 37.38 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45135 461
FHH-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 158.11 beats/min 12.95 34.27 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45140 461
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 6 222.21 beats/min 12.58 30.81 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45146 461
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 182.84 beats/min 19.78 52.34 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45149 461
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 267.31 beats/min 62.35 187.05 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45156 461
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 192.48 beats/min 9.16 27.47 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45157 461
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 232.16 beats/min 11.92 44.59 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45165 461
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 260.6 beats/min 21.86 69.14 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45163 461
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 210.35 beats/min 11.22 31.74 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45170 461
FHH-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 4 213.13 beats/min 13.85 27.7 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45179 461
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 207.52 beats/min 30.26 90.78 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45200 461
FHH-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 5 150.46 beats/min 36.22 81.0 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45201 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 13 147.76 beats/min 12.14 43.77 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45199 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 15 230.34 beats/min 28.03 108.56 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45205 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 21 227.83 beats/min 8.01 36.72 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45202 461
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 182.74 beats/min 21.3 63.9 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45207 461
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 23 237.4 beats/min 18.95 90.87 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45212 461
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 5 149.2 beats/min 30.4 67.97 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45221 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 265.53 beats/min 34.79 130.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45219 461
SS-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 167.73 beats/min 17.91 53.74 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45217 461
GK heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 147.0 beats/min 7.0 18.52 vascular transducer tipped catheter 0.0 103038 2784
GK heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) and meclofenamate (3 mg/kg) (for 0.5 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 5 301.0 beats/min 21.0 46.96 vascular transducer tipped catheter 0.0 103049 2784
GK heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) then NG-nitroarginine methyl ester (50 mg/kg) (for 0.5 hours) and meclofenamate (3 mg/kg) (for 0.5 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 279.0 beats/min 17.0 44.98 vascular transducer tipped catheter 0.0 103054 2784
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 430.16 beats/min 6.98 23.14 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18101 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 408.74 beats/min 22.8 60.31 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18103 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 449.47 beats/min 14.97 36.66 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18109 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 466.65 beats/min 11.1 31.39 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18755 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 491.55 beats/min 15.67 35.05 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18756 381
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 296.33 beats/min 106.07 150.01 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17478 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 396.45 beats/min 10.38 31.13 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17477 381
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 393.11 beats/min 14.21 42.62 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17488 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 427.79 beats/min 11.17 43.27 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17500 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 420.82 beats/min 18.01 59.74 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17506 381
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 395.92 beats/min 8.61 21.1 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17514 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 19 402.94 beats/min 12.75 55.56 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17524 381
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 381.44 beats/min 11.69 30.92 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17540 381
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 449.72 beats/min 33.88 58.69 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17543 381
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 446.64 beats/min 26.84 53.68 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17546 381
LE/BluGill heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 255.49 beats/min 10.11 31.97 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49976 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 3 316.28 beats/min 18.91 32.76 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49979 461
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 241.21 beats/min 9.9 31.31 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49980 461
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 245.03 beats/min 30.09 95.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46503 461
LE/BluGill heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 11 208.44 beats/min 17.39 57.69 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46505 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 2 272.73 beats/min 0.0 0.0 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46508 461
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 344.24 beats/min 24.49 77.43 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46515 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 252.78 beats/min 11.94 35.83 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46518 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 264.79 beats/min 37.41 105.8 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46631 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 250.09 beats/min 11.1 41.53 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47572 461
FHH-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 4 202.05 beats/min 11.75 23.49 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47575 461
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 257.93 beats/min 12.49 39.49 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47576 461
FHH-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 203.47 beats/min 12.82 36.26 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47578 461
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 217.63 beats/min 20.74 65.59 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47588 461
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 12 234.91 beats/min 5.87 20.34 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47601 461
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 12 259.78 beats/min 7.76 26.89 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47606 461
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 235.0 beats/min 8.49 25.46 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47615 461
FHH-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 224.05 beats/min 11.31 33.92 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47617 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 209.85 beats/min 7.0 19.8 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47626 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 15 230.48 beats/min 12.06 46.7 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47633 461
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 244.91 beats/min 5.23 16.55 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47634 461
SS-Chr YBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 28 235.7 beats/min 6.26 33.1 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47647 461
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 20 271.8 beats/min 5.0 22.36 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47652 461
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 247.25 beats/min 10.15 32.1 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47658 461
FHH-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 220.0 beats/min 8.17 25.83 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47662 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 304.18 beats/min 25.52 76.55 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 46632 461
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 441.09 beats/min 7.48 25.92 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16125 381
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 356.09 beats/min 15.89 61.56 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16129 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 4 303.31 beats/min 13.52 27.03 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45870 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 12 267.84 beats/min 40.9 141.69 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45134 461
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 187.11 beats/min 10.69 32.08 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45154 461
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 220.39 beats/min 8.16 25.81 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45151 461
FHH-Chr YBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 202.79 beats/min 16.98 53.71 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45161 461
FHH-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 4 214.26 beats/min 17.57 35.14 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45164 461
FHH-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 233.2 beats/min 9.6 28.81 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45166 461
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 260.7 beats/min 48.91 129.41 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45168 461
FHH-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 159.95 beats/min 16.39 46.35 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45176 461
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 14 241.21 beats/min 17.93 67.1 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45180 461
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 185.09 beats/min 10.9 32.71 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45181 461
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 17 256.37 beats/min 35.95 148.23 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45185 461
FHH-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 5 183.91 beats/min 21.14 47.27 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45183 461
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 217.83 beats/min 58.83 166.41 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45186 461
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 16 216.36 beats/min 35.27 141.07 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45196 461
SS-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 205.75 beats/min 14.15 37.43 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45215 461
FHH-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 175.02 beats/min 13.33 39.99 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45223 461
FHH-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 180.91 beats/min 8.45 25.35 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45228 461
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 176.87 beats/min 23.98 63.44 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45250 461
Crlj:WI heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 6 372.0 beats/min 11.0 26.94 vascular transducer tipped catheter 0.0 103035 2784
GK heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 5 395.0 beats/min 17.0 38.01 vascular transducer tipped catheter 0.0 103037 2784
Crlj:WI heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 6 90.0 beats/min 15.0 36.74 vascular transducer tipped catheter 0.0 103039 2784
GK heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 5 366.0 beats/min 17.0 38.01 vascular transducer tipped catheter 0.0 103045 2784
Hsd:SD heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 425.19 beats/min 13.38 53.54 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15756 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 420.82 beats/min 24.13 72.4 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18102 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 444.03 beats/min 9.59 25.39 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18106 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 463.94 beats/min 7.82 20.68 Download Values vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18757 381
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 363.66 beats/min 10.65 31.94 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17476 381
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 453.24 beats/min 20.85 69.14 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17485 381
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 411.34 beats/min 11.45 37.98 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17487 381
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 401.26 beats/min 38.1 76.2 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17490 381
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 399.96 beats/min 16.39 49.18 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17491 381
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 418.05 beats/min 9.42 26.66 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17497 381
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 403.95 beats/min 35.32 70.63 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17496 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 441.23 beats/min 11.82 40.96 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17507 381
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 423.4 beats/min 19.24 47.14 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17513 381
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 403.49 beats/min 13.9 43.95 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17522 381
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 436.02 beats/min 34.89 85.45 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17527 381
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 771.68 beats/min 175.59 430.1 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17536 381
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 437.1 beats/min 20.79 41.58 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17538 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 399.04 beats/min 8.58 30.94 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17545 381
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 425.87 beats/min 11.22 33.66 Download Values vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17541 381
Hsd:SD heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 380.39 beats/min 29.41 88.23 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 49849 461
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 247.37 beats/min 10.62 33.58 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49973 461
LEW/Crl heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 252.33 beats/min 4.17 12.51 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 49977 461
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 332.0 beats/min 62.39 197.29 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46501 461
LE/BluGill heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 226.16 beats/min 9.33 28.0 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 46510 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 6 349.16 beats/min 39.15 95.91 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 46512 461
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 16 262.5 beats/min 10.58 42.31 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47567 461
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 256.08 beats/min 11.2 31.67 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47571 461
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 266.65 beats/min 6.08 17.2 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47580 461
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 212.14 beats/min 15.56 46.68 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47586 461
FHH-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 213.58 beats/min 9.22 26.07 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47582 461
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 263.05 beats/min 5.53 16.6 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47590 461
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 19 244.69 beats/min 7.41 32.28 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47594 461
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 265.92 beats/min 7.32 23.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47604 461
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 265.46 beats/min 7.33 21.98 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47611 461
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 230.53 beats/min 8.76 27.71 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47609 461
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 18 281.08 beats/min 9.58 40.66 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47616 461
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 233.71 beats/min 10.53 33.31 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47620 461
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 242.29 beats/min 8.23 24.69 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47629 461
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 258.98 beats/min 8.46 26.75 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47631 461
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 236.15 beats/min 6.55 28.55 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47630 461
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 268.88 beats/min 13.6 40.79 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47642 461
SS-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 263.56 beats/min 5.53 15.63 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47649 461
FHH-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 223.94 beats/min 11.48 34.43 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47657 461
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 276.04 beats/min 6.73 29.34 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47656 461
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 23 264.61 beats/min 9.44 45.29 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47660 461
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 255.48 beats/min 6.01 18.99 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47663 461
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 11 241.86 beats/min 14.22 47.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 47661 461
Hsd:SD heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 410.89 beats/min 17.95 25.39 Download Values vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16122 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 285.31 beats/min 7.99 22.59 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45872 461
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 5 250.62 beats/min 16.49 36.87 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45873 461
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 236.58 beats/min 11.09 29.33 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 45079 461
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 247.62 beats/min 32.8 103.73 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45136 461
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 13 207.48 beats/min 12.18 43.92 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45133 461
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 157.95 beats/min 19.19 54.29 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45137 461
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 13 273.2 beats/min 40.93 147.57 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45138 461
FHH-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 7 138.46 beats/min 14.47 38.28 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45144 461
FHH-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 8 160.33 beats/min 11.39 32.21 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45148 461
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 196.96 beats/min 9.21 27.64 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45153 461
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 7 208.68 beats/min 8.81 23.32 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45152 461
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 10 198.22 beats/min 8.25 26.1 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45175 461
FHH-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 191.37 beats/min 9.85 29.54 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45178 461
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 9 217.7 beats/min 8.63 25.89 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45195 461
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 19 236.88 beats/min 7.82 34.08 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45209 461
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait female 49.0 days-63.0 days 10 201.83 beats/min 12.42 39.26 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45208 461
SS-Chr YBN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 28 203.53 beats/min 7.7 40.73 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45213 461
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 9 153.29 beats/min 9.05 27.15 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45220 461
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 24 222.91 beats/min 8.17 40.04 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Teklad 45225 461
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) PhysGen Cardiac data heart pumping trait male 49.0 days-63.0 days 8 226.32 beats/min 12.63 35.73 Download Values balloon tipped catheter with pressure transducer in isolated perfused heart Moms and pups used in studies were fed Dyets 45247 461
GK heart rate controlled air oxygen content (21 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 5 366.0 beats/min 17.0 38.01 vascular transducer tipped catheter 0.0 103041 2784
Crlj:WI heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 380.0 beats/min 18.0 47.62 vascular transducer tipped catheter 0.0 103040 2784
Crlj:WI heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 384.0 beats/min 17.0 44.98 vascular transducer tipped catheter 0.0 103044 2784
GK heart rate controlled air oxygen content (5 %) (for 28 days) then vehicle control condition (0.15 ml) (for 0.1 hours) then acetylcholine (5 ug/kg/min) (for 0.1 hours) then sodium nitroprusside (5 ug/kg/min) (for 0.1 hours) Chen YC, et al., Am J Physiol Regul Integr Comp Physiol. 2016 Aug 1;311(2):R426-39. doi: 10.1152/ajpregu.00112.2016. Epub 2016 Jun 1. heart pumping trait male 16.0 days 7 390.0 beats/min 10.0 26.46 vascular transducer tipped catheter 0.0 103046 2784