| Crl:WI |
heart rate |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart pumping trait |
male |
150.0 days-240.0 days |
6 |
251.8 |
beats/min |
7.0 |
17.15 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
|
langendorf prep |
25 |
min |
|
at least 6 animals |
110445 |
3174 |
| Crl:WI |
maximum rate of positive change in left ventricular blood pressure |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
6 |
3390.6 |
mmHg/s |
232.6 |
569.75 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
110449 |
3174 |
| Crl:WI |
time constant of left ventricular pressure decay |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
6 |
25.5 |
ms |
0.63 |
1.54 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
110453 |
3174 |
| Crl:WI |
time constant of left ventricular pressure decay |
controlled ex vivo heart perfusion then controlled oxygen content physiological salt solution perfusate (40 mmHg) (for 0 hours) |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
|
56.0 |
ms |
3.0 |
|
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
138481 |
3174 |
| Crl:WI |
maximum rate of positive change in left ventricular blood pressure |
controlled ex vivo heart perfusion then controlled oxygen content physiological salt solution perfusate (40 mmHg) (for 0 hours) |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
|
1027.1 |
mmHg/s |
84.0 |
|
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
138479 |
3174 |
| Crl:WI |
left ventricular systolic blood pressure |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
|
135.0 |
mmHg |
9.6 |
|
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
138477 |
3174 |
| Crl:WI |
maximum rate of negative change in left ventricular blood pressure |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
6 |
-2669.0 |
mmHg/s |
172.9 |
423.52 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
110451 |
3174 |
| Crl:WI |
coronary perfusion pressure |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
blood vessel physiology trait |
male |
150.0 days-240.0 days |
|
74.2 |
mmHg |
1.4 |
|
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals; coronary perfusion pressure (CMO:0003906) |
138471 |
3174 |
| Crl:WI |
left ventricular end-diastolic blood pressure |
controlled ex vivo heart perfusion then controlled oxygen content physiological salt solution perfusate (40 mmHg) (for 0 hours) |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
|
11.6 |
mmHg |
0.6 |
|
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
138475 |
3174 |
| Crl:WI |
coronary blood flow rate to heart weight ratio |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
blood vessel physiology trait |
male |
150.0 days-240.0 days |
|
10.9 |
ml/min/g |
0.78 |
|
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals; coronary blood flow rate to heart weight ratio (CMO:0003908) |
138473 |
3174 |
| Crl:WI |
left ventricular diastolic blood pressure |
controlled ex vivo heart perfusion |
El-Omar MM, et al., Basic Res Cardiol. 2004 Mar;99(2):133-41. doi: 10.1007/s00395-004-0440-4. Epub 2003 Oct 7. |
heart physiology trait |
male |
150.0 days-240.0 days |
6 |
126.6 |
mmHg |
9.65 |
23.64 |
balloon tipped catheter with pressure transducer in isolated perfused heart |
0.0 |
|
|
|
langendorf acclimation time 25min |
at least 6 animals |
110447 |
3174 |
