Phenominer Database Results (97 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Record ID Study ID
WKY/NHsd plasma insulin level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood insulin amount female 119.0 days 10 20.0 mU/l 2.5 7.91 intraperitoneal glucose tolerance test 0 post glucose injection 60 min 11614 107
WKY/NHsd serum thyroid stimulating hormone level control condition Baum AE, et al., Endocrinology 2004 Oct 28;. blood thyroid-stimulating hormone amount female 70.0 days- days 15 3.0 ng/ml 0.05 0.21 radioimmunoassay 0.0 serum tsh 67898 252
WKY/NHsd number of rearing movements in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. fear-related behavior trait female 77.0 days-88.0 days 16 33.8 null 2.65 10.6 visual assessment of in vivo video recording 600.0 defensive burying apparatus number of rearing movements in a defensive burying apparatus (CMO:0004096) 68652 972
WKY/NHsd number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait female 77.0 days-88.0 days 22 6.2 null 1.43 6.7 visual assessment of in vivo video recording 600.0 number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus (CMO:0004098) 75706 972
WKY/NHsd number of rearing movements in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. exploratory behavior trait male 77.0 days-88.0 days 28 9.6 null 1.38 7.3 visual assessment of in vivo video recording 600.0 in 10min 75698 972
WKY/NHsd number of rearing movements in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. exploratory behavior trait female 77.0 days-88.0 days 22 20.5 null 2.26 10.6 visual assessment of in vivo video recording 600.0 in 10min 75692 972
WKY/NHsd total accumulated grooming time in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait female 77.0 days-88.0 days 22 42.5 s 6.12 28.7 visual assessment of in vivo video recording 600.0 in 10min 75696 972
WKY/NHsd skin chloride level to skin water level ratio standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 7 42.0 mmol/l 2.4 6.35 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl/h2o 99151 2238
WKY/NHsd skin chloride level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 7 101.0 mmol/l 3.9 10.32 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na/h2o 99149 2238
WKY/NHsd skin chloride level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 7 48.0 mmol/l 4.8 12.7 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl/h2o 99153 2238
WKY/NHsd skin potassium level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin potassium amount male  days 7 71.0 mmol/l 3.0 7.94 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin k/h2o 99157 2238
WKY/NHsd plasma creatinine level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood creatinine amount male  days 8 0.32 mg/dl 0.01 0.03 plasma creatinine analysis 0.0 99174 2238
WKY/NHsd skin sodium level to skin dry weight ratio standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin sodium amount male  days 7 0.11 REQUEST NEW VALUE 0.0 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin mmol/g 99131 2238
WKY/NHsd urine sodium excretion rate standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 7 1.0 mEq/d 0.2 0.53 urine sodium analysis 0.0 mmol/d 99183 2238
WKY/NHsd skin sodium level to skin dry weight ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin sodium amount male  days 7 0.14 REQUEST NEW VALUE 0.01 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin mmol/g 99133 2238
WKY/NHsd urine sodium excretion rate controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 7 41.9 mEq/d 5.2 13.76 urine sodium analysis 0.0 99185 2238
WKY/NHsd mean arterial blood pressure standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. arterial blood pressure trait male  days 7 101.0 mmHg 0.9 2.38 intra-aortic radiotelemetry 0.0 99187 2238
WKY/NHsd mean arterial blood pressure controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. arterial blood pressure trait male  days 8 124.0 mmHg 4.0 11.31 intra-aortic radiotelemetry 0.0 99190 2238
WKY/NHsd creatinine clearance controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 7 3.5 ml/min 0.3 0.79 urine creatinine analysis 0.0 99181 2238
WKY/NHsd artery neointimal hyperplastic lesion area to total wall area ratio balloon angioplasty Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery integrity trait male 119.0 days-133.0 days 9 27.5 % 3.5 10.5 ex vivo light microscopy with digital image analysis 0.0 110481 3107
WKY/NHsd body weight control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. body mass male 119.0 days 16 318.69 g 9.83 39.31 body weighing method 138413 3200
WKY/NHsd epididymal fat pad weight control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. epididymal fat pad mass male 119.0 days 16 4.55 g 0.27 1.07 post excision weight measurement 138417 3200
WKY/NHsd plasma corticosterone level control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount male 105.0 days 24 31.7 ng/ml 4.2 20.58 radioimmunoassay ng/ml 13118 105
WKY/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount male 119.0 days 10 173.8 mg/dl 5.5 17.39 intraperitoneal glucose tolerance test 0 post glucose injection 60 min 13173 107
WKY/NHsd serum thyroid stimulating hormone level control condition Baum AE, et al., Endocrinology 2004 Oct 28;. blood thyroid-stimulating hormone amount male 70.0 days- days 16 5.28 ng/ml 0.29 1.16 radioimmunoassay 0.0 serum tsh 67897 252
WKY/NHsd total accumulated grooming time in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait female 77.0 days-88.0 days 16 97.9 s 17.75 71.0 visual assessment of in vivo video recording 600.0 defensive burying apparatus total accumulated grooming time in a defensive burying apparatus (CMO:0004097) 75700 972
WKY/NHsd skin chloride level to skin dry weight ratio standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 8 0.05 mmol/g 0.0 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl mmol/g 99136 2238
WKY/NHsd skin chloride level to skin water level ratio standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 7 90.0 mmol/l 0.8 2.12 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na/h2o 99147 2238
WKY/NHsd skin potassium level plus skin sodium level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin mineral amount male  days 8 0.17 null 0.0 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na+k/h2o 99146 2238
WKY/NHsd skin chloride level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 8 108.0 mmol/l 4.4 12.45 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na/h2o 99150 2238
WKY/NHsd skin potassium level to skin water level ratio standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin potassium amount male  days 7 80.0 mmol/l 1.1 2.91 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin k/h2o 99155 2238
WKY/NHsd skin potassium level to skin water level ratio standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin potassium amount male  days 8 75.0 mmol/l 1.8 5.09 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin k/h2o 99156 2238
WKY/NHsd plasma potassium level standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood potassium amount male  days 7 3.9 mmol/l 0.2 0.53 automated blood electrolyte analysis 0.0 99163 2238
WKY/NHsd plasma potassium level standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood potassium amount male  days 8 4.2 mmol/l 0.3 0.85 automated blood electrolyte analysis 0.0 99164 2238
WKY/NHsd plasma creatinine level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood creatinine amount male  days 7 0.3 mg/dl 0.01 0.02 plasma creatinine analysis 0.0 99173 2238
WKY/NHsd plasma cystatin C level standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood cystatin C amount male  days 7 4.0 mg/l 0.6 1.59 automated plasma protein analysis 0.0 99175 2238
WKY/NHsd both adrenal glands wet weight control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 adrenal gland mass female 112.0 days 20 65.8 mg 1.8 8.05 post excision weight measurement 11602 105
WKY/NHsd body weight fasting (for 16 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 body mass male 119.0 days 10 352.0 g 4.5 14.23 body weighing method 0 11608 107
WKY/NHsd mammary tumor number 7,12-dimethyltetraphene (65 mg/kg) Lan H, et al., Genetics 2001 Jan;157(1):331-9 mammary gland integrity trait female 169.0 days-174.0 days 17 0.0 null necropsy 3X3 mm diameter or larger 11741 141
WKY/NHsd plasma corticosterone level physical restraint (for 0.2 hours) Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount male 105.0 days 24 287.5 ng/ml 21.0 102.88 radioimmunoassay 0 ng/ml 13124 105
WKY/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount male 119.0 days 10 98.1 mg/dl 2.5 7.91 plasma glucose analysis 0 13174 107
WKY/NHsd plasma glucose level physical restraint in tube type rodent restrainer (for 0.5 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount male 105.0 days 10 153.5 mg/dl 6.3 19.92 plasma glucose analysis 0 13175 107
WKY/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount female 119.0 days 10 84.3 mg/dl 6.9 21.82 plasma glucose analysis 0 13184 107
WKY/NHsd skin water level to skin dry weight ratio standard rat chow (for 8 days) then sunitinib (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin water amount male  days 7 1.22 ml/g 0.03 0.08 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin h2o ml/g 99139 2238
WKY/NHsd skin potassium level plus skin sodium level to skin water level ratio standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin mineral amount male  days 7 0.17 null 0.0 0.0 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na+k/h2o 99143 2238
WKY/NHsd skin water level to skin dry weight ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin water amount male  days 8 1.52 ml/g 0.0 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin h2o ml/g 99142 2238
WKY/NHsd plasma sodium level standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood sodium amount male  days 7 143.7 mmol/l 4.4 11.64 automated blood electrolyte analysis 0.0 99159 2238
WKY/NHsd plasma sodium level standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood sodium amount male  days 8 137.8 mmol/l 2.3 6.51 automated blood electrolyte analysis 0.0 99160 2238
WKY/NHsd plasma potassium level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood potassium amount male  days 8 4.4 mmol/l 0.4 1.13 automated blood electrolyte analysis 0.0 99166 2238
WKY/NHsd plasma chloride level standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood chloride amount male  days 7 98.2 mmol/l 1.1 2.91 automated blood electrolyte analysis 0.0 99167 2238
WKY/NHsd plasma cystatin C level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood cystatin C amount male  days 7 3.5 mg/l 0.2 0.53 automated plasma protein analysis 0.0 99177 2238
WKY/NHsd plasma cystatin C level standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood cystatin C amount male  days 8 4.7 mg/l 0.3 0.85 automated plasma protein analysis 0.0 plasma cystatin c 99176 2238
WKY/NHsd skin sodium level to skin dry weight ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin sodium amount male  days 8 0.16 REQUEST NEW VALUE 0.01 0.03 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin mmol/g 99134 2238
WKY/NHsd urine sodium excretion rate standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 8 1.1 mEq/d 0.1 0.28 urine sodium analysis 0.0 99184 2238
WKY/NHsd mean arterial blood pressure controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. arterial blood pressure trait male  days 7 116.0 mmHg 1.0 2.65 intra-aortic radiotelemetry 0.0 99189 2238
WKY/NHsd creatinine clearance standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 7 3.1 ml/min 0.5 1.32 urine creatinine analysis 0.0 99179 2238
WKY/NHsd creatinine clearance controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 8 3.5 ml/min 0.2 0.57 urine creatinine analysis 0.0 99182 2238
WKY/NHsd artery neointimal hyperplastic lesion area balloon angioplasty Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery integrity trait male 119.0 days-133.0 days 9 0.04 mm2 0.01 0.02 ex vivo light microscopy with digital image analysis 0.0 110470 3107
WKY/NHsd body weight fasting (for 16 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 body mass female 119.0 days 10 230.0 g 3.2 10.12 body weighing method 0 11610 107
WKY/NHsd total accumulated grooming time in an open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait male 77.0 days-88.0 days 28 35.3 s 7.48 39.6 visual assessment of in vivo video recording 600.0 in 10min 68654 972
WKY/NHsd number of rearing movements in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. fear-related behavior trait male 77.0 days-88.0 days 26 17.8 null 1.45 7.4 visual assessment of in vivo video recording 600.0 defensive burying apparatus number of rearing movements in a defensive burying apparatus (CMO:0004096) 75694 972
WKY/NHsd skin chloride level to skin dry weight ratio standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 7 0.05 mmol/g 0.0 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl mmol/g 99135 2238
WKY/NHsd skin water level to skin dry weight ratio standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin water amount male  days 8 1.21 ml/g 0.02 0.05 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin h2o ml/g 99140 2238
WKY/NHsd skin chloride level to skin dry weight ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 8 0.07 mmol/g 0.01 0.02 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl mmol/g 99138 2238
WKY/NHsd skin water level to skin dry weight ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin water amount male  days 7 1.43 ml/g 0.03 0.08 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin h2o ml/g 99141 2238
WKY/NHsd skin potassium level plus skin sodium level to skin water level ratio standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin mineral amount male  days 8 0.17 null 0.0 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na+k/h2o 99144 2238
WKY/NHsd skin potassium level plus skin sodium level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin mineral amount male  days 7 0.18 null 0.01 0.02 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na+k/h2o 99145 2238
WKY/NHsd skin chloride level to skin water level ratio standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 8 92.0 mmol/l 1.5 4.24 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin na/h2o 99148 2238
WKY/NHsd skin chloride level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 8 50.0 mmol/l 4.4 12.45 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl/h2o 99154 2238
WKY/NHsd plasma chloride level standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood chloride amount male  days 8 100.5 mmol/l 0.5 1.41 automated blood electrolyte analysis 0.0 99168 2238
WKY/NHsd plasma creatinine level standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood creatinine amount male  days 7 0.31 mg/dl 0.01 0.03 plasma creatinine analysis 0.0 99171 2238
WKY/NHsd plasma chloride level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood chloride amount male  days 8 109.1 mmol/l 1.0 2.83 automated blood electrolyte analysis 0.0 99170 2238
WKY/NHsd plasma creatinine level standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood creatinine amount male  days 8 0.35 mg/dl 0.02 0.05 plasma creatinine analysis 0.0 99172 2238
WKY/NHsd skin sodium level to skin dry weight ratio standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin sodium amount male  days 8 0.11 REQUEST NEW VALUE 0.0 0.01 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin mmol/g 99132 2238
WKY/NHsd plasma chloride level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood chloride amount male  days 7 104.8 mmol/l 1.8 4.76 automated blood electrolyte analysis 0.0 99169 2238
WKY/NHsd creatinine clearance standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 8 3.1 ml/min 0.5 1.41 urine creatinine analysis 0.0 99180 2238
WKY/NHsd nose to tail body mass index control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. body mass male 119.0 days 16 2.27 (g/cm2) x 10 0.04 0.15 body weighing method 138415 3200
WKY/NHsd nose to rump body mass index control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. body mass male 119.0 days 16 7.9 (g/cm2) x 10 0.2 0.78 body weighing method 138414 3200
WKY/NHsd plasma corticosterone level control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount female 105.0 days 20 113.0 ng/ml 18.9 84.52 radioimmunoassay 13121 105
WKY/NHsd plasma corticosterone level physical restraint (for 0.2 hours) Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 blood corticosterone amount female 105.0 days 20 584.5 ng/ml 33.5 149.82 radioimmunoassay 0 13128 105
WKY/NHsd plasma glucose level physical restraint in tube type rodent restrainer (for 0.5 hours) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount female 105.0 days 10 151.6 mg/dl 4.7 14.86 plasma glucose analysis 0 13182 107
WKY/NHsd plasma glucose level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood glucose amount female 119.0 days 10 163.7 mg/dl 7.2 22.77 intraperitoneal glucose tolerance test 0 post glucose injection 60 min 13183 107
WKY/NHsd both adrenal glands wet weight control condition Solberg LC, et al., Physiol Genomics. 2006 Nov 27;27(3):362-9. Epub 2006 Aug 8 adrenal gland mass male 112.0 days 24 43.0 mg 1.2 5.88 post excision weight measurement 11600 105
WKY/NHsd plasma insulin level fasting (for 16 hours) then glucose solution (2 g/kg) Solberg Woods LC, et al., Mamm Genome. 2009 Aug 22 blood insulin amount male 119.0 days 10 64.1 mU/l 9.7 30.67 intraperitoneal glucose tolerance test 0 post glucose injection 60 min 11612 107
WKY/NHsd number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait male 77.0 days-88.0 days 28 4.0 null 0.87 4.6 visual assessment of in vivo video recording 600.0 number of lines crossed in the seven-section, 50 cm diameter center of a circular open field apparatus (CMO:0004098) 75704 972
WKY/NHsd total accumulated grooming time in a defensive burying apparatus control condition Baum AE, et al., Behav Brain Res. 2006 Feb 17;. anxiety-related behavior trait male 77.0 days-88.0 days 26 82.4 s 12.34 62.9 visual assessment of in vivo video recording 600.0 defensive burying apparatus total accumulated grooming time in a defensive burying apparatus (CMO:0004097) 75702 972
WKY/NHsd skin chloride level to skin dry weight ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 7 0.07 mmol/g 0.01 0.02 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl mmol/g 99137 2238
WKY/NHsd skin chloride level to skin water level ratio standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin chloride amount male  days 8 43.0 mmol/l 1.5 4.24 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin cl/h2o 99152 2238
WKY/NHsd plasma sodium level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood sodium amount male  days 7 141.4 mmol/l 2.1 5.56 automated blood electrolyte analysis 0.0 99161 2238
WKY/NHsd skin potassium level to skin water level ratio controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. skin potassium amount male  days 8 69.0 mmol/l 2.5 7.07 ex vivo analysis of atomic composition following dry ashing 0.0 ashed skin skin k/h2o 99158 2238
WKY/NHsd plasma sodium level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood sodium amount male  days 8 139.4 mmol/l 1.7 4.81 automated blood electrolyte analysis 0.0 99162 2238
WKY/NHsd plasma potassium level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood potassium amount male  days 7 4.2 mmol/l 0.3 0.79 automated blood electrolyte analysis 0.0 99165 2238
WKY/NHsd plasma cystatin C level controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. blood cystatin C amount male  days 8 3.9 mg/l 0.3 0.85 automated plasma protein analysis 0.0 99178 2238
WKY/NHsd urine sodium excretion rate controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 8 34.3 mEq/d 1.8 5.09 urine sodium analysis 0.0 99186 2238
WKY/NHsd mean arterial blood pressure standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. arterial blood pressure trait male  days 8 128.0 mmHg 3.0 8.49 intra-aortic radiotelemetry 0.0 99188 2238
WKY/NHsd artery neointimal hyperplastic lesion area including tunica media balloon angioplasty Assadnia S, etal., Circ Res. 1999 Jun 11;84(11):1252-7. doi: 10.1161/01.res.84.11.1252. iliac artery integrity trait male 119.0 days-133.0 days 9 0.13 mm2 0.01 0.04 ex vivo light microscopy with digital image analysis 0.0 110459 3107
WKY/NHsd retroperitoneal fat pad weight control condition Keele GR, etal., Obesity (Silver Spring). 2018 Jan;26(1):213-222. doi: 10.1002/oby.22075. Epub 2017 Nov 28. retroperitoneal fat pad mass male 119.0 days 16 4.88 g 0.66 2.63 post excision weight measurement 138416 3200