| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
11 |
-7.7 |
null |
0.07 |
0.22 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
|
62890 |
528 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
15 |
-6.98 |
null |
0.12 |
0.45 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55727 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
15 |
-7.29 |
null |
0.12 |
0.47 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
56151 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
85 |
-7.51 |
null |
0.05 |
0.43 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
55315 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
9 |
-7.24 |
null |
0.05 |
0.16 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
56177 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
10 |
-7.15 |
null |
0.07 |
0.23 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
56181 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
5 |
-7.82 |
null |
0.1 |
0.23 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
|
62896 |
528 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
13 |
-6.84 |
null |
0.2 |
0.73 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55704 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
12 |
-6.44 |
null |
0.13 |
0.44 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55712 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
90 |
-7.44 |
null |
0.05 |
0.47 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
56145 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
10 |
-7.91 |
null |
0.09 |
0.28 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
55323 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
11 |
-7.13 |
null |
0.16 |
0.54 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55719 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
12 |
-7.2 |
null |
0.06 |
0.21 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
56172 |
522 |
| SS/JrHsdMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
12 |
-7.39 |
null |
0.1 |
0.35 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
56179 |
522 |