Phenominer Database Results (102 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Individual Records Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 4 129.64 mmHg 6.29 12.58 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51742 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87 days-120 days 10 130.93 mmHg 4.07 12.88 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 51826 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80 days-99 days 9 159.75 mmHg 6.83 20.5 Download Values vascular fluid filled catheter 0 Moms were fed Teklad, pups used in studies were fed Dyets 52865 482
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 16 139.76 mmHg 3.93 15.73 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 50939 481
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 51 123.21 mmHg 1.69 12.1 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13510 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 4 104.65 mmHg 2.31 4.62 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13900 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-94 days 35 continuous mean 185.0 mmHg 5.0 29.58 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day 12004 229
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 3 115.6 mmHg 10.41 18.04 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19009 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 3 110.14 mmHg 3.1 5.37 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16029 381
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 13 serial mean 160.2 mmHg 3.5 12.62 vascular indwelling catheter method left femoral artery 120.0 0 69534 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 13 serial mean 159.0 mmHg 6.4 23.08 vascular indwelling catheter method left femoral artery 120.0 0 69538 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 13 serial mean 168.4 mmHg 7.0 25.24 vascular indwelling catheter method left femoral artery 120.0 0 69540 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (between 50 and 52 days) then controlled sodium content diet (4 %) (for 21 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. arterial blood pressure trait male 71 days-73 days 8 serial mean 151.0 mmHg 3.0 8.49 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 0 98643 2118
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 9 131.39 mmHg 4.31 12.92 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 15556 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 8 120.93 mmHg 6.37 18.01 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14410 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87 days-120 days 12 144.43 mmHg 4.76 16.47 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 51633 481
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 4 126.47 mmHg 4.99 9.97 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16023 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 11 124.5 mmHg 2.7 8.97 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 15123 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 7 126.83 mmHg 3.13 8.27 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15205 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 6 122.15 mmHg 2.63 6.45 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14652 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 15 137.62 mmHg 4.07 15.75 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 52084 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 18 144.0 mmHg 3.04 12.89 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 50734 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87 days-120 days 12 148.3 mmHg 5.49 19.02 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 51147 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86 days-89 days 12 177.0 mmHg 5.0 17.32 vascular fluid filled catheter left femoral artery 14400 0 on 3 consecutive days 5405 15
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 10 122.71 mmHg 2.46 7.78 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 14361 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 10 122.92 mmHg 3.54 11.2 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 13765 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89 days-92 days 21 serial mean 174.0 mmHg 6.0 27.5 vascular indwelling catheter method left femoral artery 0 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11854 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.1 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) and controlled exposure to darkness (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-93 days 35 continuous mean 172.0 mmHg 7.0 41.41 vascular indwelling catheter method femoral artery 14400.0 0 left femoral artery 12005 229
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 84 days 28 continuous mean 125.0 mmHg 3.0 15.87 vascular indwelling catheter method femoral artery 3.0 0 left femoral artery 12024 229
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 7 133.2 mmHg 6.56 17.36 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 19713 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 8 113.83 mmHg 3.8 10.74 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 20056 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 38 130.32 mmHg 2.26 13.93 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 18944 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 6 1/3 systolic pressure + 2/3 diastolic pressure 139.0 mmHg 4.91 12.02 Download Values radiotelemetry carotid artery 0 - 43869 441
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 13 serial mean 126.0 mmHg 4.1 14.78 vascular indwelling catheter method left femoral artery 120.0 0 69528 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 9 serial mean 159.0 mmHg 7.1 21.3 vascular indwelling catheter method left femoral artery 120.0 0 69546 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (8 %) (for 21 days) Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. arterial blood pressure trait female 91 days 13 serial mean 174.0 mmHg 5.0 18.03 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 98700 2141
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days) Flister MJ, et al., Hypertension. 2013 Apr;61(4):850-6. doi: 10.1161/HYPERTENSIONAHA.111.01008. Epub 2013 Mar 4. arterial blood pressure trait male 91 days 10 serial mean 179.0 mmHg 6.0 18.97 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 98719 2142
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87 days-120 days 10 148.46 mmHg 3.82 12.09 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 50646 481
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 62 125.01 mmHg 1.69 13.31 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 15118 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 7 130.87 mmHg 6.42 16.99 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 17772 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86 days-89 days 12 181.0 mmHg 2.9 10.05 vascular fluid filled catheter left femoral artery 259200 0 5406 15
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 11 131.45 mmHg 3.35 11.1 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 19514 381
SS/JrHsdMcwi mean arterial blood pressure control condition (0.4 %) (between 50 and 52 days) Cowley AW Jr, et al., Hypertension. 2016 Feb;67(2):440-50. doi: 10.1161/HYPERTENSIONAHA.115.06280. Epub 2015 Dec 7. arterial blood pressure trait male 50 days-52 days 8 serial mean 108.0 mmHg 1.0 2.83 intra-aortic thoracic radiotelemetry via carotid cannulation 86400.0 0 98645 2118
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 10 126.99 mmHg 3.33 10.55 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15199 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 30 days) and controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 91 days-93 days 35 continuous mean 173.0 mmHg 7.0 41.41 vascular indwelling catheter method femoral artery 259200.0 0 3 h per day decrease 66140 229
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 9 122.02 mmHg 7.52 22.57 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 14670 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92 days-94 days 12 serial mean 142.0 mmHg 5.0 17.32 vascular indwelling catheter method left femoral artery 0 0 65467 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 17 157.61 mmHg 4.84 19.98 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 51141 481
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 11 134.71 mmHg 4.19 13.9 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 13887 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 8 132.8 mmHg 6.49 18.34 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 13896 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 3 108.33 mmHg 5.29 9.16 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13906 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 48 117.4 mmHg 1.68 11.62 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 20051 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 1 152.36 mmHg Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19003 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 7 122.6 mmHg 8.28 21.9 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 20403 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (for 12 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 7 1/3 systolic pressure + 2/3 diastolic pressure 133.14 mmHg 6.74 17.84 Download Values radiotelemetry carotid artery 0 - 44425 441
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (100 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 13 serial mean 147.2 mmHg 3.9 14.06 vascular indwelling catheter method left femoral artery 120.0 0 69532 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (1 %) (for 77 days) then controlled sodium content diet (8 %) (for 7 days) Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. arterial blood pressure trait male 74 days-84 days 12 serial mean 137.0 mmHg 5.0 17.32 intra-aortic abdominal radiotelemetry 14400.0 0 abdominal aorta 4 hrs for 3 consecutive days 96861 1718
SS/JrHsdMcwi mean arterial blood pressure control condition (0.4 %) (between 23 and 32 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 44 days-53 days 14 serial mean 107.0 mmHg 1.0 3.74 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant 98472 2079
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (between 23 and 32 days) then controlled sodium content diet (8 %) (for 14 days) Cowley AW Jr, et al., Physiol Genomics. 2016 Jan;48(1):62-72. doi: 10.1152/physiolgenomics.00097.2015. Epub 2015 Nov 3. arterial blood pressure trait male 58 days-67 days 14 serial mean 163.0 mmHg 4.0 14.97 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 carotid a. to thoracic aorta implant 98493 2079
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 28 days) then controlled sodium content diet (8 %) (for 31 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 1.5 days) then controlled exposure to ambient light (for 12 hours) Cowley AW Jr, et al., Physiol Genomics 2000 Apr 27;2(3):107-15. arterial blood pressure trait male 96 days 24 continuous mean 141.0 mmHg 5.0 24.49 vascular indwelling catheter method femoral artery 10800.0 0 left femoral artery 12038 229
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 61 123.16 mmHg 2.06 16.07 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 14356 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 7 121.45 mmHg 3.1 8.21 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14120 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 15 131.99 mmHg 3.79 14.69 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 51997 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 70 days) then controlled sodium content diet (8 %) (for 21 days) Hoffman MJ, et al., Hypertension. 2013 Sep;62(3):557-63. doi: 10.1161/HYPERTENSIONAHA.113.01708. Epub 2013 Jul 1. arterial blood pressure trait male 91 days 12 serial mean 182.0 mmHg 6.0 20.78 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 98699 2141
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 18 135.0 mmHg 5.04 21.4 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 51821 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80 days-99 days 59 176.81 mmHg 2.61 20.06 Download Values vascular fluid filled catheter 0 Moms were fed Teklad, pups used in studies were fed Dyets 52859 482
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 5 126.48 mmHg 5.04 11.27 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50794 481
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 4 119.26 mmHg 4.6 9.21 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14126 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 9 130.99 mmHg 4.35 13.06 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 19704 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 50 122.9 mmHg 2.03 14.37 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 19891 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 9 120.65 mmHg 4.0 11.99 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 18949 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (for 13 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 6 1/3 systolic pressure + 2/3 diastolic pressure 131.0 mmHg 6.09 14.93 Download Values radiotelemetry carotid artery 0 - 43807 441
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (for 11 days) PhysGen Knockout data arterial blood pressure trait male 70 days-77 days 7 1/3 systolic pressure + 2/3 diastolic pressure 130.57 mmHg 4.7 12.45 Download Values radiotelemetry carotid artery 0 - 44116 441
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (20 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 13 serial mean 131.3 mmHg 4.2 15.14 vascular indwelling catheter method left femoral artery 120.0 0 69530 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then acetylcholine (0.1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 9 serial mean 132.0 mmHg 7.0 21.0 vascular indwelling catheter method left femoral artery 120.0 0 69542 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) then acetylcholine (0.1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 9 serial mean 160.0 mmHg 6.7 20.1 vascular indwelling catheter method left femoral artery 120.0 0 69548 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) then acetylcholine (0.2 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 9 serial mean 159.1 mmHg 6.4 19.2 vascular indwelling catheter method left femoral artery 120.0 0 69550 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium chloride content diet (8 %) (for 13.4 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 60 days-67 days 12 serial mean 177.0 mmHg 4.0 13.86 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry 98551 2098
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 18 157.81 mmHg 6.04 25.64 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 50640 481
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 11 131.52 mmHg 2.55 8.47 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 14661 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 10 121.8 mmHg 3.03 9.59 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13515 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 68 days) then controlled sodium content diet (8 %) (for 21 days) Moreno C, et al., Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1530-5. doi: 10.1152/ajpheart.01026.2010. Epub 2011 Jan 21. arterial blood pressure trait male 89 days 16 serial mean 186.0 mmHg 5.0 20.0 intra-aortic abdominal radiotelemetry via femoral cannulation 10800.0 0 98671 2138
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 11 131.2 mmHg 2.53 8.39 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 15547 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 7 132.16 mmHg 5.14 13.61 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14416 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 4 122.43 mmHg 4.51 9.02 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14658 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 3 118.36 mmHg 3.5 6.07 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50673 481
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 7 127.72 mmHg 7.58 20.05 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 13774 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 10 119.38 mmHg 3.99 12.63 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 19896 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82 days-99 days 8 136.24 mmHg 5.73 16.22 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 19523 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 22 136.46 mmHg 2.42 11.36 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 17763 381
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (0.5 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 13 serial mean 141.7 mmHg 7.4 26.68 vascular indwelling catheter method left femoral artery 120.0 0 69536 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then acetylcholine (0.2 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101 days-103 days 9 serial mean 134.7 mmHg 7.4 22.2 vascular indwelling catheter method left femoral artery 120.0 0 69544 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (1 %) (for 77 days) Flister MJ, et al., Hypertension. 2012 Oct;60(4):942-8. doi: 10.1161/HYPERTENSIONAHA.112.198200. Epub 2012 Aug 6. arterial blood pressure trait male 67 days-77 days 12 serial mean 121.0 mmHg 3.0 10.39 intra-aortic abdominal radiotelemetry 14400.0 0 abdominal aorta 4 hrs for 3 consecutive days 96860 1718
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (between 46 and 50.8 days) then controlled sodium content diet (8 %) (for 6.7 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 53 days-60 days 3 serial mean 139.0 mmHg 5.2 9.0 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry 98595 2098
SS/JrHsdMcwi mean arterial blood pressure control condition (0.4 %) (between 46 and 50.8 days) Cowley AW, et al., Physiol Genomics. 2014 Jun 1;46(11):398-410. doi: 10.1152/physiolgenomics.00179.2013. Epub 2014 Apr 8. arterial blood pressure trait male 46 days-53 days 3 serial mean 107.0 mmHg 3.46 6.0 intra-aortic thoracic radiotelemetry via carotid cannulation 10800.0 0 intra-carotid radiotelemetry 98602 2098
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 91 days 6 15sec/min for 3 hrs/day 175.5 mmHg 7.9 19.35 vascular fluid filled catheter 0.0 0 n=6-8 106522 3031
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82 days-99 days 10 117.48 mmHg 3.71 11.72 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 20394 381
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 5 117.49 mmHg 2.54 5.67 Download Values vascular fluid filled catheter 0 Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51324 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87 days-120 days 18 157.55 mmHg 5.0 21.21 Download Values vascular fluid filled catheter 0 Moms and pups used in studies were fed Dyets 51628 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (for 21 days) Mattson DL, et al., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30. arterial blood pressure trait not specified 84 days 4 181.0 mmHg 9.0 18.0 vascular indwelling catheter method 0.0 0 69292 1057
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89 days-91 days 15 serial mean 159.0 mmHg 6.0 23.24 vascular indwelling catheter method left femoral artery 0.0 0 69448 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 70 days 6 15sec/min for 3 hrs/day for 7days 127.5 mmHg 1.5 3.67 vascular fluid filled catheter 0.0 0 n=6-8 106520 3031