| SHRSP/A3N |
systolic blood pressure |
control condition |
Furspan PB, etal., J Hypertens. 1987 Jun;5(3):293-7. doi: 10.1097/00004872-198706000-00005. |
arterial blood pressure trait |
both |
180.0 days-270.0 days |
13 |
|
207.0 |
mmHg |
25.2 |
90.86 |
tail cuff plethysmography |
|
0.0 |
|
|
|
107637 |
3094 |
| SHRSP/A3N |
systolic blood pressure |
control condition |
Furspan PB, etal., J Hypertens. 1987 Jun;5(3):293-7. doi: 10.1097/00004872-198706000-00005. |
arterial blood pressure trait |
both |
141.0 days
| 7 |
|
194.0 |
mmHg |
16.7 |
44.18 |
tail cuff plethysmography |
|
0.0 |
|
|
|
107638 |
3094 |
| SHRSP/A3N |
systolic blood pressure |
standard condition (for 126 days) |
Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. |
arterial blood pressure trait |
male |
203.0 days-224.0 days |
10 |
|
253.0 |
mmHg |
9.0 |
28.46 |
tail cuff plethysmography |
tail |
0.0 |
|
|
standard rat chow |
107097 |
3075 |
| SHRSP/A3N |
systolic blood pressure |
control condition |
Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. |
arterial blood pressure trait |
male |
120.0 days-140.0 days |
24 |
|
244.0 |
mmHg |
4.0 |
19.6 |
tail cuff plethysmography |
|
0.0 |
|
|
|
107568 |
3093 |
| SHRSP/A3N |
systolic blood pressure |
controlled sodium chloride content drinking water (1 %) (for 84 days) and controlled fat content diet (24.5 %) (for 84 days) and eprosartan (60 mg/kg/d) (for 84 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
arterial blood pressure trait |
male |
168.0 days-189.0 days |
6 |
serial mean |
250.0 |
mmHg |
9.0 |
22.05 |
tail cuff plethysmography |
tail |
0.0 |
|
average 3 week intervals for 12 weeks |
|
107500 |
3090 |
| SHRSP/A3N |
systolic blood pressure |
controlled hydralazine content drinking water (100 mg/l) (for 60 days) and controlled hydrochlorothiazide content drinking water (100 mg/l) (for 60 days) then controlled hydralazine content drinking water (200 mg/l) (for 60 days) and controlled hydrochlorothiazide content drinking water (200 mg/l) (for 60 days) |
Furspan PB, etal., J Hypertens. 1987 Jun;5(3):293-7. doi: 10.1097/00004872-198706000-00005. |
arterial blood pressure trait |
both |
141.0 days
| 6 |
|
131.0 |
mmHg |
5.6 |
13.72 |
tail cuff plethysmography |
|
0.0 |
|
|
|
107639 |
3094 |
| SHRSP/A3N |
systolic blood pressure |
controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) and controlled carvedilol content diet (2400 ppm) (for 126 days) |
Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. |
arterial blood pressure trait |
male |
203.0 days-224.0 days |
10 |
|
260.0 |
mmHg |
6.0 |
18.97 |
tail cuff plethysmography |
tail |
0.0 |
|
|
|
107095 |
3075 |
| SHRSP/A3N |
systolic blood pressure |
reproduction condition |
Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. |
arterial blood pressure trait |
male |
120.0 days-140.0 days |
10 |
|
147.0 |
mmHg |
10.0 |
31.62 |
tail cuff plethysmography |
|
0.0 |
|
|
|
107569 |
3093 |
| SHRSP/A3N |
systolic blood pressure |
reproduction condition |
Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. |
arterial blood pressure trait |
female |
120.0 days-140.0 days |
15 |
|
94.0 |
mmHg |
10.0 |
38.73 |
tail cuff plethysmography |
|
0.0 |
|
|
|
107571 |
3093 |
| SHRSP/A3N |
systolic blood pressure |
controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) |
Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. |
arterial blood pressure trait |
male |
203.0 days-224.0 days |
10 |
|
267.0 |
mmHg |
7.0 |
22.14 |
tail cuff plethysmography |
tail |
0.0 |
|
|
high salt high fat diet |
107096 |
3075 |
| SHRSP/A3N |
systolic blood pressure |
control condition |
Wexler BC, Stroke. 1980 Nov-Dec;11(6):665-71. doi: 10.1161/01.str.11.6.665. |
arterial blood pressure trait |
female |
120.0 days-140.0 days |
24 |
|
230.0 |
mmHg |
6.0 |
29.39 |
tail cuff plethysmography |
|
0.0 |
|
|
|
107570 |
3093 |
| SHRSP/A3N |
systolic blood pressure |
controlled sodium chloride content drinking water (1 %) (for 84 days) and controlled fat content diet (24.5 %) (for 84 days) and vehicle control condition (for 84 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
arterial blood pressure trait |
male |
168.0 days-189.0 days |
6 |
serial mean |
284.0 |
mmHg |
8.0 |
19.6 |
tail cuff plethysmography |
tail |
0.0 |
|
average 3 week intervals for 12 weeks |
|
107499 |
3090 |