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Strain
Phenotype
Conditions
Study
Experiment Name
Sex
Age
# of Animals
Value
Units
SEM
SD
Individual Records
Method
Method Duration
Post Insult Time Value
Experiment Notes
Record ID
Study ID
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
male
70.0 days-84.0 days
15
99.27
%
0.6
2.31
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
57116
522
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
salidroside (40 mg/kg) (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
98.36
%
0.98
2.59
wire myography
0.0
103599
2827
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
vehicle control condition (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
96.54
%
1.9
5.03
wire myography
0.0
103614
2827
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
female
70.0 days-84.0 days
9
99.33
%
0.37
1.12
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
56858
522
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
vehicle control condition (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
97.56
%
1.02
2.7
wire myography
0.0
103598
2827
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
salidroside (40 mg/kg) (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
90.13
%
1.55
4.1
wire myography
0.0
103615
2827
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
male
70.0 days-84.0 days
14
99.29
%
0.27
0.99
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
56851
522
WKY/NCrl
sodium nitroprusside-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
phenylephrine (1 umol/l) (for 0.2 hours) then sodium nitroprusside (0-3 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
female
70.0 days-84.0 days
12
99.67
%
0.26
0.89
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
57123
522