| WKY/NCrl |
diastolic blood pressure |
salidroside (40 mg/kg) (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
87.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
|
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
103551 |
2827 |
| WKY/NCrl |
diastolic blood pressure |
controlled sodium content diet (8 %) (for 14 days) then controlled exposure to ambient light (for 14 days) |
Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. |
arterial blood pressure trait |
male |
126.0 days
| 7 |
89.3 |
mmHg |
0.76 |
2.0 |
vascular indwelling catheter method |
left common carotid artery |
0.0 |
|
|
daytime (7 AM - 7 PM) |
70087 |
1281 |
| WKY/NCrl |
diastolic blood pressure |
vehicle control condition (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
85.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
measured 12 hr/day for 4 weeks |
daytime measurement |
103542 |
2827 |
| WKY/NCrl |
diastolic blood pressure |
salidroside (40 mg/kg) (for 28 days) and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
83.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
|
|
measured 12 hr/day for 4 weeks |
daytime measurement |
103543 |
2827 |
| WKY/NCrl |
diastolic blood pressure |
controlled exposure to darkness (for 12 hours) |
Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. |
arterial blood pressure trait |
male |
112.0 days
| 7 |
92.5 |
mmHg |
1.59 |
4.2 |
vascular indwelling catheter method |
left common carotid artery |
0.0 |
|
|
nighttime (7 PM - 7 AM) |
70084 |
1281 |
| WKY/NCrl |
diastolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133.0 days-140.0 days |
6 |
85.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
103538 |
2827 |
| WKY/NCrl |
diastolic blood pressure |
vehicle control condition (for 28 days) and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
168.0 days
| 6 |
89.0 |
mmHg |
3.0 |
7.35 |
intra-aortic abdominal radiotelemetry |
|
|
|
measured 12 hr/night for 4 weeks |
nighttime measurement |
103550 |
2827 |
| WKY/NCrl |
diastolic blood pressure |
controlled exposure to ambient light (for 12 hours) |
Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. |
arterial blood pressure trait |
male |
112.0 days
| 7 |
88.7 |
mmHg |
0.83 |
2.2 |
vascular indwelling catheter method |
left common carotid artery |
0.0 |
|
|
daytime (7 AM - 7 PM) |
70083 |
1281 |
| WKY/NCrl |
diastolic blood pressure |
controlled sodium content diet (8 %) (for 14 days) then controlled exposure to darkness (for 12 hours) |
Iwai N, et al., Circulation 1999 Nov 2;100(18):1923-9. |
arterial blood pressure trait |
male |
126.0 days
| 7 |
93.9 |
mmHg |
1.29 |
3.4 |
vascular indwelling catheter method |
left common carotid artery |
0.0 |
|
|
nighttime (7 PM - 7 AM) |
70088 |
1281 |
| WKY/NCrl |
diastolic blood pressure |
control condition and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133.0 days-140.0 days |
6 |
87.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
measured 12 hr/night for 1 week |
nighttime measurement |
103547 |
2827 |
| WKY/NCrl |
diastolic blood pressure |
control condition and light phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133.0 days-140.0 days |
6 |
82.0 |
mmHg |
2.0 |
4.9 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
measured 12 hr/day for 1 week |
daytime measurement |
103539 |
2827 |
| WKY/NCrl |
diastolic blood pressure |
control condition and dark phase of controlled light/dark cycle (for 12 hours) |
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57. |
arterial blood pressure trait |
male |
133.0 days-140.0 days |
6 |
89.0 |
mmHg |
4.0 |
9.8 |
intra-aortic abdominal radiotelemetry |
|
0.0 |
|
measured 12 hr/night for 1 week |
nighttime measurement |
103546 |
2827 |