| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
5 |
-7.39 |
null |
0.08 |
0.17 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
56173 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
6 |
-7.47 |
null |
0.16 |
0.39 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55711 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
8 |
-6.26 |
null |
0.09 |
0.24 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55726 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
10 |
-7.76 |
null |
0.12 |
0.37 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
56119 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
5 |
-7.56 |
null |
0.12 |
0.27 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
56176 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
6 |
-8.11 |
null |
0.11 |
0.27 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
|
63097 |
528 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
119 |
-8.15 |
null |
0.03 |
0.33 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
|
63108 |
528 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
8 |
-8.35 |
null |
0.09 |
0.24 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
55289 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
10 |
-7.37 |
null |
0.11 |
0.33 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55705 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
54 |
-7.85 |
null |
0.09 |
0.65 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
56138 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
8 |
-6.18 |
null |
0.08 |
0.22 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Dyets |
55720 |
522 |
| FHH/EurMcwi |
logarithm of the concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (Log EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
50 |
-7.86 |
null |
0.05 |
0.35 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
EC50 value is moles/liter |
Moms and pups used in studies were fed Teklad |
55308 |
522 |