FHH-Chr 4BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
0.68 |
E-7mole |
0.13 |
0.39 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55939 |
522 |
FHH-Chr 4BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
78.0 |
% |
4.57 |
13.7 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54828 |
522 |
FHH-Chr 4BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
0.81 |
E-7mole |
0.11 |
0.32 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56568 |
522 |
FHH-Chr 4BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
86.56 |
% |
6.03 |
18.09 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
54824 |
522 |
FHH-Chr 4BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
-7.01 |
null |
0.14 |
0.42 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56959 |
522 |
FHH-Chr 4BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
76.9 |
% |
4.19 |
13.25 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
57274 |
522 |
FHH-Chr 4BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
-7.18 |
null |
0.04 |
0.13 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55675 |
522 |
FHH-Chr 4BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
10 |
0.69 |
E-7mole |
0.06 |
0.19 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55944 |
522 |
FHH-Chr 4BN/Mcwi |
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
86.44 |
% |
6.32 |
18.95 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
57269 |
522 |
FHH-Chr 4BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
-7.22 |
null |
0.07 |
0.21 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
55670 |
522 |
FHH-Chr 4BN/Mcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70 days-84 days |
9 |
1.55 |
E-7mole |
0.56 |
1.69 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56564 |
522 |
FHH-Chr 4BN/Mcwi |
logarithm of the concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (Log EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70 days-84 days |
9 |
-7.12 |
null |
0.06 |
0.17 |
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
0 |
Moms and pups used in studies were fed Teklad |
56963 |
522 |