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| Strain |
Phenotype |
Conditions |
Study |
Experiment Name |
Sex |
Age |
# of Animals |
Value |
Units |
SEM |
SD |
Method |
Method Duration |
Post Insult Time Value |
Method Notes |
Clinical Measurement Notes |
Record ID |
Study ID |
| Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170.0 days
| 8 |
0.19 |
umol/g |
0.01 |
0.03 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
|
enzyme recycling method |
reduced liver glutathione level to liver weight ratio |
85574 |
1604 |
| Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170.0 days
| 8 |
0.14 |
umol/g |
0.0 |
0.01 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
|
enzyme recycling method |
|
85577 |
1604 |
| Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170.0 days
| 8 |
0.24 |
umol/g |
0.01 |
0.02 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
|
enzyme recycling method |
reduced liver glutathione level to liver weight ratio |
85573 |
1604 |
| Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170.0 days
| 19 |
0.17 |
umol/g |
0.0 |
0.02 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
|
enzyme recycling method |
|
85409 |
1604 |
| Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170.0 days
| 8 |
0.16 |
umol/g |
0.01 |
0.03 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
|
enzyme recycling method |
|
85576 |
1604 |
| Crl:CD(SD) |
liver oxidized glutathione level to liver weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver glutathione amount |
male |
170.0 days
| 19 |
0.21 |
umol/g |
0.01 |
0.03 |
reduced glutathione/oxidized glutathione enzyme recycling assay |
0.0 |
|
enzyme recycling method |
oxidized liver glutathione level to liver weight ratio |
85408 |
1604 |
|