Phenominer Database Results (269 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
F344/DuCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 9 1.22 ml/min 0.12 0.37 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51686 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 14 1.94 ml/min 0.2 0.73 urine creatinine analysis Moms and pups used in studies were fed Dyets 51797 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 6 1.43 ml/min 0.07 0.17 urine creatinine analysis Moms and pups used in studies were fed Dyets 51799 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 8 1.77 ml/min 0.16 0.45 urine creatinine analysis Moms and pups used in studies were fed Dyets 51803 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 3 1.73 ml/min 0.18 0.32 urine creatinine analysis Moms and pups used in studies were fed Dyets 51801 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 8 2.38 ml/min 0.13 0.38 urine creatinine analysis Moms and pups used in studies were fed Dyets 51807 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 5 1.67 ml/min 0.2 0.45 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51931 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 1.72 ml/min 0.12 0.29 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51936 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 14 1.64 ml/min 0.17 0.64 urine creatinine analysis Moms and pups used in studies were fed Teklad 51944 481
SS-Chr 14BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 9 1.62 ml/min 0.21 0.64 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52143 482
SS-Chr 14BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 1.79 ml/min 0.18 0.47 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52147 482
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 2.25 ml/min 0.21 0.6 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52162 482
SS-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 2.03 ml/min 0.27 0.71 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52165 482
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 1.75 ml/min 0.2 0.58 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52170 482
SS-Chr 4BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 0.11 ml/min 0.01 0.03 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52176 482
SS-Chr XBN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 3 1.6 ml/min 0.34 0.59 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52173 482
SS-Chr 1BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 14 2.08 ml/min 0.21 0.79 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52172 482
SS-Chr 12BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 5 2.85 ml/min 0.21 0.48 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52180 482
BN/NHsdMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 1.74 ml/min 0.15 0.44 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52186 482
SS-Chr 4BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 0.09 ml/min 0.01 0.04 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52182 482
SS-Chr XBN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 3 2.43 ml/min 0.72 1.25 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52188 482
LE/BluGill creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 6 2.56 ml/min 0.2 0.5 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52291 482
FHH-Chr 6BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 9 1.69 ml/min 0.15 0.46 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52348 482
FHH-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 2.81 ml/min 0.46 1.22 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52354 482
FHH-Chr 2BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 4 2.06 ml/min 0.53 1.06 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52365 482
FHH-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 6 0.81 ml/min 0.12 0.29 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52367 482
FHH/EurMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 39 1.44 ml/min 0.09 0.57 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52360 482
FHH-Chr 4BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.26 ml/min 0.12 0.31 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52372 482
BN/NHsdMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.23 ml/min 0.15 0.4 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52380 482
LEW/Crl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 4 1.83 ml/min 0.27 0.53 urine creatinine analysis 50574 481
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 5 0.83 ml/min 0.17 0.38 urine creatinine analysis Moms and pups used in studies were fed Teklad 51057 481
SS-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 10 1.2 ml/min 0.12 0.38 urine creatinine analysis Moms and pups used in studies were fed Teklad 51061 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 4 1.21 ml/min 0.21 0.42 urine creatinine analysis Moms and pups used in studies were fed Teklad 51062 481
SS-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 12 0.56 ml/min 0.15 0.53 urine creatinine analysis Moms and pups used in studies were fed Teklad 51059 481
Crl:CD(SD) creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 2.46 ml/min 0.22 0.54 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51256 481
F344/DuCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 5 1.04 ml/min 0.2 0.44 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51257 481
Hsd:SD creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 9 1.85 ml/min 0.15 0.44 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51402 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 6 1.5 ml/min 0.12 0.3 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51449 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 4 1.14 ml/min 0.06 0.13 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51450 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 5 1.54 ml/min 0.24 0.55 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51452 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 1.92 ml/min 0.12 0.28 urine creatinine analysis Moms and pups used in studies were fed Dyets 51540 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 1.27 ml/min 0.09 0.19 urine creatinine analysis Moms and pups used in studies were fed Dyets 51543 481
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 5 1.42 ml/min 0.18 0.41 urine creatinine analysis Moms and pups used in studies were fed Dyets 51550 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 8 1.36 ml/min 0.12 0.35 urine creatinine analysis Moms and pups used in studies were fed Dyets 51549 481
SHR/NHsdMco creatinine clearance to total kidney weight ratio control condition (for 140 days) Garrett MR, et al., Physiol Genomics. 2007 May 15;. glomerular filtration trait male 140.0 days 6 0.8 ml/min/g 0.03 0.07 urine creatinine analysis 0.0 creatinine clearance to total kidney weight ratio 68018 834
SS/JrTol creatinine clearance to total kidney weight ratio control condition (for 140 days) Garrett MR, et al., Physiol Genomics. 2007 May 15;. glomerular filtration trait male 140.0 days 6 0.75 ml/min/g 0.02 0.04 urine creatinine analysis 0.0 creatinine clearance to total kidney weight ratio 68020 834
BN/NHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 25 56.4 mg/dl 4.95 24.75 urine creatinine analysis 0.0 69475 151
BN/NHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 25 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 mg/min 69477 151
BN/NHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 92.0 days-94.0 days 8 1.1 ml/min 0.2 0.57 urine creatinine analysis 0.0 mg/min 69479 151
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 92.0 days-94.0 days 10 1.08 ml/min 0.37 1.17 urine creatinine analysis 0.0 mg/min 69480 151
SS creatinine clearance controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 91.0 days 8 2.8 ml/min 0.07 0.2 urine creatinine analysis 0.0 102288 2683
SS-Plod1em1Mcwi-/- urine creatinine excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60.0 days-69.0 days 9.0 mg/d 0.4 urine creatinine analysis 0.0 98437 2059
SS.ZUC-Leprfa+/+/Slc creatinine clearance to body weight ratio control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. glomerular filtration trait male 126.0 days 6 0.91 ml/min/100g 0.06 0.15 urine creatinine analysis 0.0 101939 2642
PCK-Pkhd1pck/CrljCrl creatinine clearance control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. glomerular filtration trait male 60.0 days 3 0.0 ml/min 0.0 0.0 urine creatinine analysis 0.0 100209 2439
SS-Renem1Mcwi+/- urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine creatinine amount male 56.0 days 8 4.85 mg/d 0.28 0.79 urine creatinine analysis 0.0 98333 2038
WKY/NHsd creatinine clearance controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 7 3.5 ml/min 0.3 0.79 urine creatinine analysis 0.0 99181 2238
WAG/Nov creatinine clearance to body weight ratio controlled sucrose content drinking water (4 %) (for 2 days) and solid food deprivation (for 2 days) Ivanova LN, et al., Exp Physiol. 2013 Nov;98(11):1608-19. doi: 10.1113/expphysiol.2013.073163. Epub 2013 Aug 16. glomerular filtration trait not specified  days 4 0.22 ml/min/100g 0.02 0.05 urine creatinine analysis 0.0 107193 3078
WAG/Nov creatinine clearance to body weight ratio sodium chloride solution (1 ml) (for 2 days) Ivanova LN, et al., Exp Physiol. 2013 Nov;98(11):1608-19. doi: 10.1113/expphysiol.2013.073163. Epub 2013 Aug 16. glomerular filtration trait not specified  days 4 0.18 ml/min/100g 0.03 0.07 urine creatinine analysis 0.0 107191 3078
MWF creatinine clearance controlled enalapril content drinking water (10 mg/kg) (between 0 and 336 hours) Schie�l IM, etal., J Pharmacol Exp Ther. 2015 May;353(2):299-306. doi: 10.1124/jpet.114.222125. Epub 2015 Feb 13. glomerular filtration trait male 379.0 days 6 3.44 ml/min 0.1 0.24 urine creatinine analysis 0.0 108065 3113
MWF/FubRkb creatinine clearance left nephrectomy (for 84 days) then controlled ramipril content drinking water (1 mg/kg/d) (for 28 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84.0 days 15 0.92 ml/min 0.05 0.19 urine creatinine analysis 0.0 109650 3149
Hsd:SD creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 11 2.61 ml/min 0.23 0.77 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51747 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 10 2.35 ml/min 0.14 0.44 urine creatinine analysis Moms and pups used in studies were fed Dyets 51802 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 1 1.05 ml/min urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51934 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 1.27 ml/min 0.15 0.33 urine creatinine analysis Moms and pups used in studies were fed Teklad 51943 481
SS-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 13 1.13 ml/min 0.2 0.73 urine creatinine analysis Moms and pups used in studies were fed Teklad 51948 481
WKY/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 0.94 ml/min 0.17 0.39 urine creatinine analysis 52030 481
SS-Chr 17BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 5 3.45 ml/min 1.21 2.69 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52153 482
SS-Chr 5BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 6 2.69 ml/min 0.11 0.28 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52156 482
SS-Chr 3BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 2.03 ml/min 0.32 0.9 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52161 482
SS-Chr 13BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 15 2.38 ml/min 0.23 0.87 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52167 482
SS-Chr 11BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 14 2.51 ml/min 0.24 0.9 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52168 482
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 53 2.17 ml/min 0.11 0.8 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52171 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 10 1.53 ml/min 0.14 0.43 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52178 482
SS-Chr 19BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 3 2.44 ml/min 0.21 0.36 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52179 482
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 9 1.7 ml/min 0.13 0.39 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52177 482
BN/NHsdMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 15 1.13 ml/min 0.14 0.55 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52187 482
SS-Chr 2BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 9 2.27 ml/min 0.15 0.46 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52189 482
LE/BluGill creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 9 2.14 ml/min 0.15 0.45 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52290 482
FHH-Chr 12BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.1 ml/min 0.19 0.5 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52339 482
FHH-Chr 8BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 6 1.35 ml/min 0.16 0.4 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52341 482
FHH-Chr 5BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 5 1.71 ml/min 0.18 0.41 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52345 482
FHH-Chr 13BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.73 ml/min 0.25 0.66 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52353 482
FHH-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 1.07 ml/min 0.15 0.39 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52356 482
FHH-Chr 14BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 1.55 ml/min 0.16 0.45 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52363 482
FHH-Chr 10BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.82 ml/min 0.35 0.94 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52366 482
FHH-Chr 1BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 2.39 ml/min 0.19 0.49 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52368 482
FHH-Chr 11BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 3 1.71 ml/min 0.15 0.27 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52373 482
BN/NHsdMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 2.55 ml/min 0.26 0.72 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52379 482
FHH-Chr 7BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 1.24 ml/min 0.29 0.81 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52383 482
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 1.14 ml/min 0.11 0.24 urine creatinine analysis Moms and pups used in studies were fed Teklad 51051 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 9 0.71 ml/min 0.07 0.2 urine creatinine analysis Moms and pups used in studies were fed Teklad 51054 481
Crl:CD(SD) creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 3 1.5 ml/min 0.2 0.34 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51258 481
F344/DuCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 8 0.92 ml/min 0.08 0.22 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51259 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 7 1.45 ml/min 0.17 0.46 urine creatinine analysis Moms and pups used in studies were fed Dyets 51542 481
SD creatinine clearance nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 6 2.6 ml/min 0.2 0.49 urine creatinine analysis 0.0 unx 84 days 100136 2419
SDT/Jcl creatinine clearance nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 6 2.7 ml/min 0.3 0.73 urine creatinine analysis 0.0 unx 84 days 100135 2419
SR/Hsd creatinine clearance standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 49.0 days 8 3.5 ml/min 0.07 0.2 urine creatinine analysis 0.0 102287 2683
SR/Hsd creatinine clearance controlled sodium chloride content diet (8 %) (for 42 days) Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 91.0 days 8 6.1 ml/min 0.28 0.8 urine creatinine analysis 0.0 102289 2683
SS-Nppbem2Mcwi-/- urine creatinine excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60.0 days-69.0 days 11.5 mg/d 0.5 urine creatinine analysis 0.0 98438 2059
SS.ZUC-Leprfa-/-/Slc creatinine clearance to total kidney weight ratio control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. glomerular filtration trait male 126.0 days 7 0.2 ml/min/g 0.03 0.08 urine creatinine analysis 0.0 101938 2642
SS.ZUC-Leprfa-/-/Slc creatinine clearance to body weight ratio control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. glomerular filtration trait male 126.0 days 7 0.18 ml/min/100g 0.02 0.05 urine creatinine analysis 0.0 101940 2642
SHRSP/Gcrc urine creatinine level vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. urine creatinine amount male 126.0 days 17 6.85 mg/dl 2.77 11.4 urine creatinine analysis 0.0 102151 2646
SD creatinine clearance control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. glomerular filtration trait male 60.0 days 3 0.0 ml/min 0.0 0.0 urine creatinine analysis 0.0 100210 2439
SD creatinine clearance control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. glomerular filtration trait male 180.0 days 5 0.0 ml/min 0.0 0.0 urine creatinine analysis 0.0 100214 2439
BRAT-Avpdi/BluHsd creatinine clearance to body weight ratio desmopressin (100 ug/kg) (for 2 days) Ivanova LN, et al., Exp Physiol. 2013 Nov;98(11):1608-19. doi: 10.1113/expphysiol.2013.073163. Epub 2013 Aug 16. glomerular filtration trait not specified  days 5 0.09 ml/min/100g 0.03 0.06 urine creatinine analysis 0.0 107195 3078
Hsd:WI creatinine clearance control condition Rothermund L, etal., J Hypertens. 2006 Sep 24(9). glomerular filtration trait not specified 100.0 days 2.76 ml/min 0.17 urine creatinine analysis 0.0 108105 3115
Crl:CD(SD) creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 1.19 ml/min 0.22 0.48 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51685 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 7 1.73 ml/min 0.16 0.42 urine creatinine analysis Moms and pups used in studies were fed Dyets 51796 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 7 1.45 ml/min 0.13 0.33 urine creatinine analysis Moms and pups used in studies were fed Dyets 51798 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 6 1.67 ml/min 0.22 0.55 urine creatinine analysis Moms and pups used in studies were fed Dyets 51805 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 1.39 ml/min 0.1 0.23 urine creatinine analysis Moms and pups used in studies were fed Teklad 51947 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 8 1.35 ml/min 0.12 0.34 urine creatinine analysis Moms and pups used in studies were fed Teklad 51950 481
SS-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 12 1.5 ml/min 0.09 0.31 urine creatinine analysis Moms and pups used in studies were fed Teklad 51953 481
BN/NHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 6 1.28 ml/min 0.07 0.17 urine creatinine analysis Moms and pups used in studies were fed Teklad 51956 481
SS.BN-(D12Arb13-D12Rat79)/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 8 1.68 ml/min 0.46 1.31 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52146 482
SS-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 8 1.12 ml/min 0.13 0.36 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52148 482
SS-Chr 6BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 1.87 ml/min 0.24 0.68 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52149 482
SS-Chr 5BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.96 ml/min 0.13 0.33 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52154 482
SS-Chr 7BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 11 1.76 ml/min 0.1 0.34 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52155 482
SS-Chr 15BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 3 1.78 ml/min 0.21 0.37 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52160 482
SS-Chr YBN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 12 2.76 ml/min 0.28 0.96 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52169 482
SS-Chr 1BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 13 1.67 ml/min 0.16 0.58 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52175 482
SS-Chr 19BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.05 ml/min 0.32 0.85 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52181 482
FHH-Chr 2BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 5 1.71 ml/min 0.2 0.44 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52346 482
FHH-Chr 3BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 1 0.7 ml/min urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52344 482
FHH-Chr 8BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 3 1.88 ml/min 0.43 0.75 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52352 482
FHH-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 6 2.06 ml/min 0.39 0.95 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52357 482
FHH-Chr 13BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 10 1.17 ml/min 0.23 0.73 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52355 482
FHH-Chr 17BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 6 0.89 ml/min 0.26 0.64 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52370 482
FHH-Chr XBN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 6 1.27 ml/min 0.24 0.59 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52374 482
FHH-Chr 17BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 11 0.76 ml/min 0.11 0.37 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52371 482
FHH-Chr 7BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.44 ml/min 0.23 0.6 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52377 482
FHH-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 3 1.57 ml/min 1.04 1.8 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52376 482
BN/NHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 3 1.39 ml/min 0.23 0.41 urine creatinine analysis Moms and pups used in studies were fed Teklad 51063 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 4 1.51 ml/min 0.23 0.45 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51448 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 4 1.66 ml/min 0.1 0.2 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51447 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 15 1.61 ml/min 0.19 0.75 urine creatinine analysis Moms and pups used in studies were fed Dyets 51541 481
BN/NHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 2 1.55 ml/min 0.17 0.24 urine creatinine analysis Moms and pups used in studies were fed Dyets 51548 481
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 7 1.08 ml/min 0.08 0.2 urine creatinine analysis Moms and pups used in studies were fed Dyets 51544 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 7 1.93 ml/min 0.1 0.27 urine creatinine analysis Moms and pups used in studies were fed Dyets 51546 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 90.0 days-94.0 days 13 1.2 ml/min 0.2 0.72 urine creatinine analysis 0.0 plasma creatinine analysis 67284 151
SS.SHR-(D2Rat61-D2Mco18)/Mco creatinine clearance to total kidney weight ratio control condition (for 140 days) Garrett MR, et al., Physiol Genomics. 2007 May 15;. glomerular filtration trait male 140.0 days 6 0.78 ml/min/g 0.03 0.06 urine creatinine analysis 0.0 creatinine clearance to total kidney weight ratio 68019 834
SS/JrHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 17 31.2 mg/dl 2.74 11.3 urine creatinine analysis 0.0 69456 151
LL/Mav urine creatinine excretion rate vehicle control condition Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. urine creatinine amount male 49.0 days-56.0 days 13 7.1 mg/d 0.3 1.08 urine creatinine analysis 0.0 102650 2703
LH/Mav urine creatinine excretion rate streptozotocin (75 mg/kg) Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. urine creatinine amount male 49.0 days-56.0 days 37 8.6 mg/d 0.3 1.82 urine creatinine analysis 0.0 102652 2703
LH/Mav urine creatinine excretion rate vehicle control condition Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. urine creatinine amount male 49.0 days-56.0 days 8 8.0 mg/d 0.3 0.85 urine creatinine analysis 0.0 102651 2703
SDT/Jcl creatinine clearance nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 7 2.3 ml/min 0.2 0.53 urine creatinine analysis 0.0 unx 84 days 100137 2419
SD creatinine clearance nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 6 2.3 ml/min 0.3 0.73 urine creatinine analysis 0.0 unx 84 days 100140 2419
SS-Clcn6em2Mcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60.0 days-69.0 days 8.3 mg/d 0.3 urine creatinine analysis 0.0 98440 2059
SS-Agtrapem4Mcwi-/- urine creatinine excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60.0 days-69.0 days 10.3 mg/d 0.9 urine creatinine analysis 0.0 98442 2059
SS/Hsd urine creatinine excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60.0 days-69.0 days 11.5 mg/d 0.4 urine creatinine analysis 0.0 98443 2059
SS.ZUC-Leprfa+/+/Slc creatinine clearance to total kidney weight ratio control condition Hattori T, et al., Nutr Diabetes. 2011 Jan 31;1:e1. doi: 10.1038/nutd.2010.1. glomerular filtration trait male 126.0 days 6 1.25 ml/min/g 0.12 0.29 urine creatinine analysis 0.0 101937 2642
WKY/Gcrc urine creatinine level vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. urine creatinine amount male 126.0 days 18 13.91 mg/dl 5.29 22.45 urine creatinine analysis 0.0 102152 2646
SS-Renem1Mcwi+/+ urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine creatinine amount male 56.0 days 5 7.94 mg/d 0.82 1.83 urine creatinine analysis 0.0 98331 2038
SS-Renem1Mcwi+/- urine creatinine excretion rate controlled sodium chloride content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine creatinine amount female 56.0 days 9 5.4 mg/d 0.18 0.54 urine creatinine analysis 0.0 98335 2038
WKY/NHsd creatinine clearance standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 7 3.1 ml/min 0.5 1.32 urine creatinine analysis 0.0 99179 2238
WKY/NHsd creatinine clearance controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 8 3.5 ml/min 0.2 0.57 urine creatinine analysis 0.0 99182 2238
HsdCpb:WU creatinine clearance sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84.0 days 15 2.76 ml/min 0.17 0.66 urine creatinine analysis 0.0 109645 3149
MWF/FubRkb creatinine clearance sham surgical control condition (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84.0 days 15 2.36 ml/min 0.14 0.54 urine creatinine analysis 0.0 109646 3149
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 0.97 ml/min 0.1 0.22 urine creatinine analysis Moms and pups used in studies were fed Dyets 51800 481
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 1.53 ml/min 0.06 0.16 urine creatinine analysis Moms and pups used in studies were fed Dyets 51806 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 1.5 ml/min 0.11 0.27 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51930 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 4 1.44 ml/min 0.11 0.22 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51933 481
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 2.03 ml/min 0.15 0.38 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51935 481
SS-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 12 0.96 ml/min 0.09 0.3 urine creatinine analysis Moms and pups used in studies were fed Teklad 51945 481
SS-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 14 0.77 ml/min 0.16 0.61 urine creatinine analysis Moms and pups used in studies were fed Teklad 51951 481
BN/NHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 3 1.49 ml/min 0.16 0.28 urine creatinine analysis Moms and pups used in studies were fed Teklad 51955 481
LEW/Crl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 5 1.64 ml/min 0.16 0.36 urine creatinine analysis 52028 481
SS-Chr 10BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 8 1.42 ml/min 0.15 0.42 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52150 482
SS-Chr 17BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 5 2.41 ml/min 0.57 1.27 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52151 482
SS-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 9 1.15 ml/min 0.17 0.51 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52158 482
SS-Chr 3BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 5 1.84 ml/min 0.2 0.46 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52164 482
SS-Chr 11BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 11 1.7 ml/min 0.22 0.74 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52166 482
SS-Chr 2BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 10 1.53 ml/min 0.14 0.44 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52183 482
SS-Chr 12BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 3 2.21 ml/min 0.03 0.06 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52185 482
FHH-Chr 19BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 6 1.76 ml/min 0.34 0.83 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52343 482
FHH-Chr 14BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 4 1.09 ml/min 0.1 0.21 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52347 482
FHH-Chr 5BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 1.6 ml/min 0.12 0.32 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52351 482
FHH-Chr YBN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 4 1.34 ml/min 0.09 0.18 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52364 482
FHH-Chr 15BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 2.4 ml/min 0.46 1.23 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52361 482
FHH-Chr 11BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 5 1.06 ml/min 0.21 0.48 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52375 482
FHH-Chr 10BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 4 1.62 ml/min 0.23 0.47 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52378 482
FHH-Chr XBN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 4 0.96 ml/min 0.2 0.4 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52381 482
FHH-Chr 1BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 9 1.3 ml/min 0.18 0.54 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52385 482
WKY/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 6 1.14 ml/min 0.14 0.34 urine creatinine analysis 50575 481
SS-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 10 1.13 ml/min 0.15 0.46 urine creatinine analysis Moms and pups used in studies were fed Teklad 51053 481
SS-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 12 0.79 ml/min 0.17 0.6 urine creatinine analysis Moms and pups used in studies were fed Teklad 51056 481
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 4 0.59 ml/min 0.17 0.33 urine creatinine analysis Moms and pups used in studies were fed Teklad 51060 481
BN/NHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 3 0.8 ml/min 0.26 0.45 urine creatinine analysis Moms and pups used in studies were fed Teklad 51064 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 2 0.73 ml/min 0.02 0.02 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51451 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 4 1.77 ml/min 0.13 0.26 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51453 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 3 1.69 ml/min 0.06 0.1 urine creatinine analysis Moms and pups used in studies were fed Dyets 51545 481
BN/NHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 90.0 days-94.0 days 10 1.7 ml/min 0.2 0.63 urine creatinine analysis 0.0 plasma creatinine analysis 67283 151
SS/JrHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 17 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 ug/min 69463 151
LL/Mav urine creatinine excretion rate vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. urine creatinine amount male 112.0 days 9 11.1 mg/d 0.5 1.5 urine creatinine analysis 0.0 102746 2721
LL/Mav urine creatinine excretion rate streptozotocin (100 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. urine creatinine amount male 112.0 days 18 9.8 mg/d 0.3 1.27 urine creatinine analysis 0.0 102747 2721
SDT/Jcl creatinine clearance controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 6 4.5 ml/min 0.5 1.22 urine creatinine analysis 0.0 x days 100133 2419
SDT/Jcl creatinine clearance nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.3 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 6 2.4 ml/min 0.2 0.49 urine creatinine analysis 0.0 unx 84 days 100139 2419
SD creatinine clearance nephrectomy then controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) and paricalcitol (0.1 ug/kg) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 8 2.3 ml/min 0.3 0.85 urine creatinine analysis 0.0 unx 84 days 100138 2419
SS-Mthfrem1Mcwi-/+ urine creatinine excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60.0 days-69.0 days 12.1 mg/d 0.4 urine creatinine analysis 0.0 98441 2059
SHRSP.WKY-(D3Mgh16-rs65433898)/Gcrc urine creatinine level vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. urine creatinine amount male 126.0 days 7 12.38 mg/dl 3.61 9.54 urine creatinine analysis 0.0 102154 2646
SHRSP.WKY-(D3Mgh16-D3Rat114)/Gcrc urine creatinine level vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. urine creatinine amount male 126.0 days 9 10.42 mg/dl 1.8 5.41 urine creatinine analysis 0.0 102153 2646
SHRSP.WKY-(D3Mgh16-D3Mit10)/Gcrc urine creatinine level vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. urine creatinine amount male 126.0 days 6 5.37 mg/dl 1.52 3.73 urine creatinine analysis 0.0 102155 2646
PCK-Pkhd1pck/CrljCrl creatinine clearance control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. glomerular filtration trait male 120.0 days 3 0.0 ml/min 0.0 0.0 urine creatinine analysis 0.0 100211 2439
SS-Renem1Mcwi+/+ urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine creatinine amount female 56.0 days 8 6.05 mg/d 0.18 0.51 urine creatinine analysis 0.0 98334 2038
SS-Renem1Mcwi+/- urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine creatinine amount male 56.0 days 9 8.41 mg/d 0.4 1.2 urine creatinine analysis 0.0 98332 2038
SS-Renem1Mcwi+/- urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine creatinine amount female 56.0 days 4 3.88 mg/d 0.61 1.22 urine creatinine analysis 0.0 98336 2038
WKY/NHsd creatinine clearance standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. glomerular filtration trait male  days 8 3.1 ml/min 0.5 1.41 urine creatinine analysis 0.0 99180 2238
SHRSP/A3NCrl creatinine clearance control condition (for 91 days) Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. glomerular filtration trait male 161.0 days-175.0 days 7 2.4 ml/min 0.1 0.26 urine creatinine analysis 0.0 107387 3083
SHRSP/A3NCrl creatinine clearance controlled sodium chloride content drinking water (1 %) (for 91 days) and controlled fat content diet (24.5 %) (for 91 days) then vehicle control condition (for 35 days) Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. glomerular filtration trait male 161.0 days-175.0 days 6 2.0 ml/min 0.2 0.49 urine creatinine analysis 0.0 107388 3083
SHRSP/A3NCrl creatinine clearance controlled sodium chloride content drinking water (1 %) (for 91 days) and controlled fat content diet (24.5 %) (for 91 days) then controlled SB-239063 content diet (1200 ppm) (for 35 days) Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. glomerular filtration trait male 161.0 days-175.0 days 8 2.0 ml/min 0.2 0.57 urine creatinine analysis 0.0 107389 3083
WAG/Nov creatinine clearance to body weight ratio desmopressin (100 ug/kg) (for 2 days) Ivanova LN, et al., Exp Physiol. 2013 Nov;98(11):1608-19. doi: 10.1113/expphysiol.2013.073163. Epub 2013 Aug 16. glomerular filtration trait not specified  days 4 0.16 ml/min/100g 0.02 0.05 urine creatinine analysis 0.0 107194 3078
MWF creatinine clearance control condition Schie�l IM, etal., J Pharmacol Exp Ther. 2015 May;353(2):299-306. doi: 10.1124/jpet.114.222125. Epub 2015 Feb 13. glomerular filtration trait male 365.0 days 6 1.64 ml/min 0.3 0.73 urine creatinine analysis 0.0 108064 3113
HsdCpb:WU creatinine clearance left nephrectomy (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84.0 days 15 0.47 ml/min 0.06 0.23 urine creatinine analysis 0.0 109647 3149
F344/DuCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 7 1.34 ml/min 0.23 0.62 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51684 481
Crl:CD(SD) creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 2.0 ml/min 0.19 0.48 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51683 481
Hsd:SD creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 15 1.81 ml/min 0.13 0.51 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51748 481
BN/NHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 2 1.65 ml/min 0.23 0.32 urine creatinine analysis Moms and pups used in studies were fed Dyets 51804 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 7 1.61 ml/min 0.15 0.38 urine creatinine analysis Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51932 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 9 1.0 ml/min 0.08 0.24 urine creatinine analysis Moms and pups used in studies were fed Teklad 51946 481
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 6 1.2 ml/min 0.09 0.22 urine creatinine analysis Moms and pups used in studies were fed Teklad 51949 481
SHR/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 6 0.78 ml/min 0.07 0.16 urine creatinine analysis Moms and pups used in studies were fed Teklad 51952 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 5 1.86 ml/min 0.28 0.63 urine creatinine analysis Moms and pups used in studies were fed Teklad 51954 481
WKY/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 9 1.5 ml/min 0.15 0.45 urine creatinine analysis 52027 481
LEW/Crl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 4 2.35 ml/min 0.29 0.57 urine creatinine analysis 52029 481
SS.BN-(D12Arb13-D12Rat79)/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 9 1.96 ml/min 0.15 0.44 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52142 482
SS-Chr 10BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 10 2.09 ml/min 0.55 1.74 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52141 482
SS-Chr 6BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.3 ml/min 0.1 0.28 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52144 482
SS-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 8 1.85 ml/min 0.19 0.55 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52145 482
SS-Chr 7BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 9 2.08 ml/min 0.16 0.48 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52152 482
SS-Chr 15BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 2.52 ml/min 0.27 0.71 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52159 482
SS-Chr 20BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 8 1.39 ml/min 0.14 0.4 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52157 482
SS-Chr 13BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 18 1.39 ml/min 0.09 0.38 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52163 482
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 8 1.26 ml/min 0.18 0.5 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52174 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 18 2.08 ml/min 0.15 0.64 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52184 482
FHH/EurMcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 12 1.47 ml/min 0.25 0.85 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52342 482
FHH-Chr 15BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 9 2.36 ml/min 0.15 0.46 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52340 482
FHH-Chr 19BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 7 1.94 ml/min 0.27 0.72 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52349 482
FHH-Chr 6BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 5 1.28 ml/min 0.12 0.27 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52350 482
FHH-Chr 3BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 3 0.68 ml/min 0.25 0.44 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52362 482
FHH-Chr 12BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 10 1.33 ml/min 0.14 0.44 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52358 482
FHH-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait female 80.0 days-99.0 days 8 1.02 ml/min 0.14 0.41 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52359 482
FHH-Chr 4BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 5 0.98 ml/min 0.12 0.26 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52369 482
FHH-Chr 16BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 7 1.55 ml/min 0.35 0.92 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52384 482
FHH-Chr 9BN/Mcwi creatinine clearance controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data glomerular filtration trait male 80.0 days-99.0 days 4 1.64 ml/min 0.13 0.25 urine creatinine analysis Moms were fed Teklad, pups used in studies were fed Dyets 52382 482
LEW/Crl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 6 1.17 ml/min 0.1 0.25 urine creatinine analysis 50573 481
WKY/NCrl creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 9 1.54 ml/min 0.09 0.27 urine creatinine analysis 50572 481
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 12 1.26 ml/min 0.24 0.84 urine creatinine analysis Moms and pups used in studies were fed Teklad 51052 481
SS-Chr 18BN/Mcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 4 1.03 ml/min 0.2 0.41 urine creatinine analysis Moms and pups used in studies were fed Teklad 51055 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 8 1.29 ml/min 0.23 0.66 urine creatinine analysis Moms and pups used in studies were fed Teklad 51058 481
Hsd:SD creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait female 87.0 days-120.0 days 13 1.09 ml/min 0.1 0.37 urine creatinine analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51403 481
FHH/EurMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 9 2.23 ml/min 0.08 0.25 urine creatinine analysis Moms and pups used in studies were fed Dyets 51547 481
GH/OmrMcwi creatinine clearance controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data glomerular filtration trait male 87.0 days-120.0 days 8 2.13 ml/min 0.12 0.33 urine creatinine analysis Moms and pups used in studies were fed Dyets 51551 481
BN/NHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 23 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 ug/min 69462 151
SS/JrHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 17 111.7 mg/dl 10.5 43.29 urine creatinine analysis 0.0 69476 151
SS/JrHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 16 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 mg/min 69478 151
BN/NHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 24 30.2 mg/dl 3.87 18.96 urine creatinine analysis 0.0 69455 151
LH/Mav urine creatinine excretion rate vehicle control condition Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. urine creatinine amount male 112.0 days 11 12.9 mg/d 0.4 1.33 urine creatinine analysis 0.0 102748 2721
LH/Mav urine creatinine excretion rate streptozotocin (75 mg/kg) Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. urine creatinine amount male 112.0 days 14 13.3 mg/d 0.2 0.75 urine creatinine analysis 0.0 102749 2721
SD creatinine clearance controlled content diet (1.2 %) (for 70 days) then controlled content diet (1 %) (for 70 days) Watanabe K, et al., J Atheroscler Thromb. 2017 Jul 1. doi: 10.5551/jat.40170. glomerular filtration trait male 140.0 days 6 5.2 ml/min 0.4 0.98 urine creatinine analysis 0.0 x days 100134 2419
SS creatinine clearance standard diet Wu F, et al., Int J Hypertens. 2016;2016:9146870. doi: 10.1155/2016/9146870. Epub 2016 Dec 19. glomerular filtration trait male 49.0 days 8 4.2 ml/min 0.25 0.7 urine creatinine analysis 0.0 102286 2683
SS-Nppaem4Mcwi-/- urine creatinine excretion rate controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine creatinine amount male 60.0 days-69.0 days 10.1 mg/d 0.3 urine creatinine analysis 0.0 98439 2059
SD creatinine clearance control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. glomerular filtration trait male 120.0 days 3 0.0 ml/min 0.0 0.0 urine creatinine analysis 0.0 100212 2439
PCK-Pkhd1pck/CrljCrl creatinine clearance control condition Goto M, et al., Pediatr Nephrol. 2010 Dec;25(12):2449-57. doi: 10.1007/s00467-010-1621-z. Epub 2010 Aug 27. glomerular filtration trait male 180.0 days 4 0.0 ml/min 0.0 0.0 urine creatinine analysis 0.0 100213 2439
BRAT-Avpdi/BluHsd creatinine clearance to body weight ratio sodium chloride solution (1 ml) (for 2 days) Ivanova LN, et al., Exp Physiol. 2013 Nov;98(11):1608-19. doi: 10.1113/expphysiol.2013.073163. Epub 2013 Aug 16. glomerular filtration trait not specified  days 4 0.2 ml/min/100g 0.02 0.03 urine creatinine analysis 0.0 107192 3078
Hsd:WI creatinine clearance control condition Rothermund L, etal., J Hypertens. 2006 Sep 24(9). glomerular filtration trait not specified 100.0 days 2.36 ml/min 0.14 urine creatinine analysis 0.0 108106 3115
MWF creatinine clearance controlled enalapril content drinking water (10 mg/kg) (between 0 and 672 hours) Schie�l IM, etal., J Pharmacol Exp Ther. 2015 May;353(2):299-306. doi: 10.1124/jpet.114.222125. Epub 2015 Feb 13. glomerular filtration trait male 393.0 days 6 3.58 ml/min 0.3 0.73 urine creatinine analysis 0.0 108066 3113
MWF/FubRkb creatinine clearance left nephrectomy (for 84 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84.0 days 15 0.57 ml/min 0.07 0.27 urine creatinine analysis 0.0 109648 3149
HsdCpb:WU creatinine clearance left nephrectomy (for 84 days) then controlled ramipril content drinking water (1 mg/kg/d) (for 28 days) Rothermund L, etal., Am J Hypertens. 2011 Apr;24(4):474-81. doi: 10.1038/ajh.2010.206. Epub 2010 Sep 23. glomerular filtration trait not specified 84.0 days 15 1.12 ml/min 0.1 0.39 urine creatinine analysis 0.0 109649 3149