Phenominer Database Results (32 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SD-Abcb1aem1Sage-/- aqueous humor uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 42 days-56 days 3 24.8 % 1.4 2.42 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index aqueous humor molecular composition trait 106147 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 42 days-56 days 3 21.0 % 2.4 4.16 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index aqueous humor molecular composition trait 106149 3028
SD-Abcb1aem1Sage-/- brain uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and vehicle control condition Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 75.0 % 5.8 10.05 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index 106165 3028
SD-Abcb1aem1Sage-/- verapamil apparent influx permeability clearance in retina tritiated verapamil (10 uCi) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 0.85 ml/min/g 0.57 0.98 liquid scintillation counting 0.0 carotid injection 15 sec post excision 106105 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 35 days-49 days 3 12.5 % 0.7 1.21 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index aqueous humor molecular composition trait 106142 3028
SD-Abcb1aem1Sage-/- brain uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 1.68 % 0.07 0.12 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index 106164 3028
SD-Abcb1aem1Sage-/- brain uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and vinblastine (1 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 74.0 % 8.3 14.38 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index 106166 3028
SD-Abcb1aem1Sage-/- rapidly equilibrated distribution volume of verapamil in brain tritiated verapamil (10 uCi) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 3.75 ml/g 0.08 0.13 liquid scintillation counting 0.0 carotid injection 15 sec post excision 106113 3028
SD-Abcb1aem1Sage-/- retinal uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 182.0 % 24.0 41.57 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index 106124 3028
SD-Abcb1aem1Sage-/- retinal uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 88.0 % 29.7 51.44 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index 106126 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and digoxin (0.01 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 42 days-56 days 3 11.0 % 0.5 0.87 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index aqueous humor molecular composition trait 106145 3028
SD-Abcb1aem1Sage-/- brain uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 75.5 % 6.3 10.91 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index 106167 3028
SD-Abcb1aem1Sage-/- rapidly equilibrated distribution volume of verapamil in aqueous humor tritiated verapamil (10 uCi) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 42 days-56 days 3 0.13 ml/g 0.0 0.0 liquid scintillation counting 0.0 carotid injection 15 sec post excision aqueous humor molecular composition trait 106112 3028
SD-Abcb1aem1Sage-/- verapamil apparent influx permeability clearance in aqueous humor tritiated verapamil (10 uCi) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 42 days-56 days 3 0.01 ml/min/g 0.0 0.0 liquid scintillation counting 0.0 carotid injection 15 sec post excision ml/(min x g) aqueous humor molecular composition trait 106106 3028
SD-Abcb1aem1Sage-/- rapidly equilibrated distribution volume of verapamil in retina tritiated verapamil (10 uCi) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 6.25 ml/g 0.76 1.32 liquid scintillation counting 0.0 carotid injection 15 sec post excision 106111 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 42 days-56 days 3 12.0 % 0.6 1.04 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index aqueous humor molecular composition trait 106141 3028
SD-Abcb1aem1Sage-/- retinal uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 536.0 % 6.0 10.39 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index 106129 3028
SD-Abcb1aem1Sage-/- retinal uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and vinblastine (1 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 362.0 % 53.0 91.8 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index 106130 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 35 days-49 days 3 8.83 % 0.4 0.69 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index aqueous humor molecular composition trait 106143 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 35 days-49 days 3 55.9 % 13.2 22.86 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index aqueous humor molecular composition trait 106144 3028
SD-Abcb1aem1Sage-/- brain uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 12.4 % 1.7 2.94 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index 106161 3028
SD-Abcb1aem1Sage-/- brain uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and digoxin (0.01 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 1.83 % 0.07 0.12 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index 106163 3028
SD-Abcb1aem1Sage-/- retinal uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 227.0 % 25.0 43.3 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index 106123 3028
SD-Abcb1aem1Sage-/- retinal uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 379.0 % 18.0 31.18 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index 106131 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of verapamil tritiated verapamil (10 uCi) (for 0 hours) and verapamil (1 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 35 days-49 days 3 13.4 % 0.5 0.87 liquid scintillation counting 0.0 carotid injection 15 sec post excision verapamil uptake index aqueous humor molecular composition trait 106148 3028
SD-Abcb1aem1Sage-/- brain uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and vehicle control condition Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 26.1 % 2.4 4.16 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index 106159 3028
SD-Abcb1aem1Sage-/- brain uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and quinidine (10 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 21.6 % 0.6 1.04 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index 106160 3028
SD-Abcb1aem1Sage-/- brain uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and vehicle control condition Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. brain molecular composition trait male 42 days-56 days 3 14.0 % 7.3 12.64 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index 106162 3028
SD-Abcb1aem1Sage-/- retinal uptake index of quinidine tritiated quinidine (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 142.0 % 5.0 8.66 liquid scintillation counting 0.0 carotid injection 15 sec post excision quinidine uptake index 106125 3028
SD-Abcb1aem1Sage-/- retinal uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and digoxin (0.01 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 18.8 % 3.1 5.37 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index 106127 3028
SD-Abcb1aem1Sage-/- retinal uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. retina molecular composition trait male 42 days-56 days 3 27.0 % 3.2 5.54 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index 106128 3028
SD-Abcb1aem1Sage-/- aqueous humor uptake index of digoxin tritiated digoxin (10 uCi) (for 0 hours) and verapamil (3 mmol/l) (for 0 hours) Fujii S, et al., Invest Ophthalmol Vis Sci. 2014 Jul 1;55(7):4650-8. doi: 10.1167/iovs.13-13819. REQUEST NEW TERM (00:0000000) male 42 days-56 days 3 10.3 % 1.1 1.91 liquid scintillation counting 0.0 carotid injection 15 sec post excision digoxin uptake index aqueous humor molecular composition trait 106146 3028