| LH/Mav |
renal blood flow rate to kidney weight ratio |
hydralazine (75 mg/kg/d) (for 63 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
renal blood flow trait |
male |
84.0 days
| 10 |
|
4.7 |
ml/min/g |
0.3 |
0.95 |
ultrasonic flowmeter |
0.0 |
|
102856 |
2761 |
| LH/Mav |
renal blood flow rate |
right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
renal blood flow trait |
male |
350.0 days
| 7 |
|
5.8 |
ml/min/g |
0.3 |
0.79 |
ultrasonic flowmeter |
0.0 |
|
104581 |
2970 |
| LH/Mav |
renal blood flow rate to kidney weight ratio |
vehicle control condition then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
renal blood flow trait |
male |
84.0 days
| 8 |
|
5.0 |
ml/min/g |
0.3 |
0.85 |
ultrasonic flowmeter |
0.0 |
|
102853 |
2761 |
| LH/Mav |
glomerular filtration rate to kidney weight ratio |
right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
glomerular filtration trait |
male |
112.0 days
| 8 |
|
0.99 |
ml/min/g |
0.08 |
0.23 |
ultrasonic flowmeter |
0.0 |
|
104591 |
2970 |
| LH/Mav |
renal blood flow rate |
right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
renal blood flow trait |
male |
112.0 days
| 9 |
|
10.2 |
ml/min/g |
0.3 |
0.9 |
ultrasonic flowmeter |
0.0 |
|
104599 |
2970 |
| LH/Mav |
renal blood flow rate |
right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
renal blood flow trait |
male |
112.0 days
| 8 |
|
8.7 |
ml/min/g |
0.6 |
1.7 |
ultrasonic flowmeter |
0.0 |
|
104601 |
2970 |
| LH/Mav |
renal vascular resistance to kidney weight ratio |
vehicle control condition then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
kidney blood vessel physiology trait |
male |
84.0 days
| 8 |
SBP/RBF |
33.0 |
ml/min/g/mmHg |
2.0 |
5.66 |
ultrasonic flowmeter |
0.0 |
|
102857 |
2761 |
| LH/Mav |
renal blood flow rate to kidney weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
renal blood flow trait |
male |
84.0 days
| 7 |
|
5.3 |
ml/min/g |
0.5 |
1.32 |
ultrasonic flowmeter |
0.0 |
|
102854 |
2761 |
| LH/Mav |
renal blood flow rate to kidney weight ratio |
nifedipine (50 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
renal blood flow trait |
male |
84.0 days
| 7 |
|
4.9 |
ml/min/g |
0.5 |
1.32 |
ultrasonic flowmeter |
0.0 |
|
102855 |
2761 |
| LH/Mav |
renal blood flow rate |
bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
renal blood flow trait |
male |
35.0 days
| 9 |
|
3.3 |
ml/min/g |
0.2 |
0.6 |
ultrasonic flowmeter |
0.0 |
|
104577 |
2970 |
| LH/Mav |
renal blood flow rate |
right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
renal blood flow trait |
male |
112.0 days
| 8 |
|
8.7 |
ml/min/g |
0.6 |
1.7 |
ultrasonic flowmeter |
0.0 |
|
104579 |
2970 |
| LH/Mav |
glomerular filtration rate to kidney weight ratio |
right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
glomerular filtration trait |
male |
350.0 days
| 7 |
|
0.51 |
ml/min/g |
0.13 |
0.34 |
ultrasonic flowmeter |
0.0 |
|
104593 |
2970 |
| LH/Mav |
glomerular filtration rate to kidney weight ratio |
right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
glomerular filtration trait |
male |
112.0 days
| 9 |
|
2.09 |
ml/min/g |
0.42 |
1.26 |
ultrasonic flowmeter |
0.0 |
|
104607 |
2970 |
| LH/Mav |
glomerular filtration rate to kidney weight ratio |
right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
glomerular filtration trait |
male |
112.0 days
| 8 |
|
0.99 |
ml/min/g |
0.08 |
0.23 |
ultrasonic flowmeter |
0.0 |
|
104609 |
2970 |
| LH/Mav |
renal vascular resistance to kidney weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
kidney blood vessel physiology trait |
male |
84.0 days
| 7 |
SBP/RBF |
23.0 |
ml/min/g/mmHg |
2.0 |
5.29 |
ultrasonic flowmeter |
0.0 |
|
102858 |
2761 |
| LH/Mav |
renal vascular resistance to kidney weight ratio |
nifedipine (50 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
kidney blood vessel physiology trait |
male |
84.0 days
| 7 |
SBP/RBF |
37.0 |
ml/min/g/mmHg |
5.0 |
13.23 |
ultrasonic flowmeter |
0.0 |
|
102868 |
2761 |
| LH/Mav |
renal vascular resistance to kidney weight ratio |
hydralazine (75 mg/kg/d) (for 63 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) |
Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. |
kidney blood vessel physiology trait |
male |
84.0 days
| 10 |
SBP/RBF |
27.0 |
ml/min/g/mmHg |
2.0 |
6.32 |
ultrasonic flowmeter |
0.0 |
|
102869 |
2761 |
| LH/Mav |
glomerular filtration rate to kidney weight ratio |
bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction |
Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. |
glomerular filtration trait |
male |
35.0 days
| 9 |
|
0.99 |
ml/min/g |
0.14 |
0.42 |
ultrasonic flowmeter |
0.0 |
|
104589 |
2970 |