Phenominer Database Results (41 results)

 
 
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Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Value Units SEM SD Method Method Duration Post Insult Time Value Clinical Measurement Notes Record ID Study ID
FHH.FHH.1BN-(D1Rat287-D1Rat84)/Mcwi ratio of change in renal blood flow to change in renal perfusion pressure controlled in situ renal perfusion pressure (100-140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait not specified 140.0 days 6 0.2 null 0.03 0.07 ultrasonic flowmeter 0.0 69884 1156
LH/Mav renal blood flow rate to kidney weight ratio hydralazine (75 mg/kg/d) (for 63 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. renal blood flow trait male 84.0 days 10 4.7 ml/min/g 0.3 0.95 ultrasonic flowmeter 0.0 102856 2761
LH/Mav renal blood flow rate right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 350.0 days 7 5.8 ml/min/g 0.3 0.79 ultrasonic flowmeter 0.0 104581 2970
LL/Mav glomerular filtration rate to kidney weight ratio right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 112.0 days 6 1.25 ml/min/g 0.07 0.17 ultrasonic flowmeter 0.0 104610 2970
FHH.FHH.1BN-(D1Rat183-D1Rat76)/Mcwi ratio of change in renal blood flow to change in renal perfusion pressure controlled in situ renal perfusion pressure (100-140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait not specified 140.0 days 9 0.61 null 0.06 0.18 ultrasonic flowmeter 0.0 69883 1156
LH/Mav renal blood flow rate to kidney weight ratio vehicle control condition then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. renal blood flow trait male 84.0 days 8 5.0 ml/min/g 0.3 0.85 ultrasonic flowmeter 0.0 102853 2761
LL/Mav glomerular filtration rate to kidney weight ratio bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 35.0 days 9 1.01 ml/min/g 0.07 0.21 ultrasonic flowmeter 0.0 104590 2970
LL/Mav glomerular filtration rate to kidney weight ratio right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 112.0 days 6 1.25 ml/min/g 0.07 0.17 ultrasonic flowmeter 0.0 104592 2970
LL/Mav glomerular filtration rate to kidney weight ratio right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 350.0 days 7 1.18 ml/min/g 0.25 0.66 ultrasonic flowmeter 0.0 104594 2970
LH/Mav glomerular filtration rate to kidney weight ratio right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 112.0 days 8 0.99 ml/min/g 0.08 0.23 ultrasonic flowmeter 0.0 104591 2970
LH/Mav renal blood flow rate right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 112.0 days 9 10.2 ml/min/g 0.3 0.9 ultrasonic flowmeter 0.0 104599 2970
LH/Mav renal blood flow rate right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 112.0 days 8 8.7 ml/min/g 0.6 1.7 ultrasonic flowmeter 0.0 104601 2970
FHH/EurMcwi renal blood flow rate controlled in situ renal perfusion pressure (140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait male 140.0 days 12 7.95 ml/min/g 0.5 1.73 ultrasonic flowmeter 0.0 69369 1156
FHH.FHH.1BN-(D1Rat173F6B-D1Rat84)/Mcwi ratio of change in renal blood flow to change in renal perfusion pressure controlled in situ renal perfusion pressure (100-140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait not specified 140.0 days 8 0.2 null 0.06 0.17 ultrasonic flowmeter 0.0 69885 1156
FHH.FHH.1BN-(D1Mgh13-D1Rat89)/Mcwi ratio of change in renal blood flow to change in renal perfusion pressure controlled in situ renal perfusion pressure (100-140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait not specified 140.0 days 9 0.23 null 0.04 0.12 ultrasonic flowmeter 0.0 69886 1156
LH/Mav renal vascular resistance to kidney weight ratio vehicle control condition then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. kidney blood vessel physiology trait male 84.0 days 8 SBP/RBF 33.0 ml/min/g/mmHg 2.0 5.66 ultrasonic flowmeter 0.0 102857 2761
LH/Mav renal blood flow rate to kidney weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. renal blood flow trait male 84.0 days 7 5.3 ml/min/g 0.5 1.32 ultrasonic flowmeter 0.0 102854 2761
LH/Mav renal blood flow rate to kidney weight ratio nifedipine (50 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. renal blood flow trait male 84.0 days 7 4.9 ml/min/g 0.5 1.32 ultrasonic flowmeter 0.0 102855 2761
LH/Mav renal blood flow rate bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 35.0 days 9 3.3 ml/min/g 0.2 0.6 ultrasonic flowmeter 0.0 104577 2970
LH/Mav renal blood flow rate right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 112.0 days 8 8.7 ml/min/g 0.6 1.7 ultrasonic flowmeter 0.0 104579 2970
LL/Mav renal blood flow rate right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 112.0 days 6 10.6 ml/min/g 0.7 1.71 ultrasonic flowmeter 0.0 104602 2970
LL/Mav glomerular filtration rate to kidney weight ratio right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 112.0 days 9 2.39 ml/min/g 0.84 2.52 ultrasonic flowmeter 0.0 104608 2970
SS.LEW-(D5Rat130-D5Rat31)/JrMcwi renal arterial blood flow rate controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. renal blood flow trait male 70.0 days 8 6.6 ml/min/g 0.5 1.41 ultrasonic flowmeter 1200 64953 272
SS/JrHsdMcwi renal arterial blood flow rate controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. renal blood flow trait male 70.0 days 10 4.7 ml/min/g 0.2 0.63 ultrasonic flowmeter 1200 64952 272
FHH/EurMcwi ratio of change in renal blood flow to change in renal perfusion pressure controlled in situ renal perfusion pressure (100-140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait male 140.0 days 12 0.8 null 0.08 0.28 ultrasonic flowmeter 0.0 69370 1156
FHH-Chr 1BN/Mcwi ratio of change in renal blood flow to change in renal perfusion pressure controlled in situ renal perfusion pressure (100-140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait male 140.0 days 12 0.19 null 0.05 0.17 ultrasonic flowmeter 0.0 69371 1156
FHH.FHH.1BN-(D1Rat234-D1Rat265)/Mcwi ratio of change in renal blood flow to change in renal perfusion pressure controlled in situ renal perfusion pressure (100-140 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait not specified 140.0 days 6 0.55 null 0.07 0.17 ultrasonic flowmeter 0.0 69882 1156
LL/Mav renal blood flow rate right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 112.0 days 6 10.6 ml/min/g 0.7 1.71 ultrasonic flowmeter 0.0 104580 2970
LH/Mav glomerular filtration rate to kidney weight ratio right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 350.0 days 7 0.51 ml/min/g 0.13 0.34 ultrasonic flowmeter 0.0 104593 2970
LH/Mav glomerular filtration rate to kidney weight ratio right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 112.0 days 9 2.09 ml/min/g 0.42 1.26 ultrasonic flowmeter 0.0 104607 2970
LH/Mav glomerular filtration rate to kidney weight ratio right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 112.0 days 8 0.99 ml/min/g 0.08 0.23 ultrasonic flowmeter 0.0 104609 2970
SS/JrHsdMcwi timed urine volume to body weight ratio controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine output male 70.0 days 10 6.9 ul/min/g 0.7 2.21 ultrasonic flowmeter 1200 urine flow to wt ratio 64926 272
SS/JrHsdMcwi timed urine volume to body weight ratio controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (150 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (170-175 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine output male 70.0 days 10 13.7 ul/min/g 2.1 6.64 ultrasonic flowmeter 1200.0 urine flow to wt ratio 64927 272
FHH/EurMcwi renal blood flow rate controlled in situ renal perfusion pressure (100 mmHg) Lopez B, et al., Am J Physiol Renal Physiol. 2006 May;290(5):F1213-21. Epub 2005 Nov 22. renal blood flow trait male 140.0 days 12 6.16 ml/min/g 0.43 1.49 ultrasonic flowmeter 0.0 69368 1156
LH/Mav renal vascular resistance to kidney weight ratio perindopril (1.5 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. kidney blood vessel physiology trait male 84.0 days 7 SBP/RBF 23.0 ml/min/g/mmHg 2.0 5.29 ultrasonic flowmeter 0.0 102858 2761
LH/Mav renal vascular resistance to kidney weight ratio nifedipine (50 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. kidney blood vessel physiology trait male 84.0 days 7 SBP/RBF 37.0 ml/min/g/mmHg 5.0 13.23 ultrasonic flowmeter 0.0 102868 2761
LH/Mav renal vascular resistance to kidney weight ratio hydralazine (75 mg/kg/d) (for 63 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then ketamine (20 mg/kg) and thiobutabarbital (75 mg/kg) Issiakhem M, et al., J Cardiovasc Pharmacol. 2008 Mar;51(3):280-5. doi: 10.1097/FJC.0b013e31816299a5. kidney blood vessel physiology trait male 84.0 days 10 SBP/RBF 27.0 ml/min/g/mmHg 2.0 6.32 ultrasonic flowmeter 0.0 102869 2761
LL/Mav renal blood flow rate bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 35.0 days 9 4.9 ml/min/g 0.3 0.9 ultrasonic flowmeter 0.0 104578 2970
LL/Mav renal blood flow rate right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 350.0 days 7 10.2 ml/min/g 0.5 1.32 ultrasonic flowmeter 0.0 104582 2970
LH/Mav glomerular filtration rate to kidney weight ratio bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. glomerular filtration trait male 35.0 days 9 0.99 ml/min/g 0.14 0.42 ultrasonic flowmeter 0.0 104589 2970
LL/Mav renal blood flow rate right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. renal blood flow trait male 112.0 days 9 9.9 ml/min/g 0.5 1.5 ultrasonic flowmeter 0.0 104600 2970