| SS/HsdMcwiCrl |
food intake rate |
controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
eating behavior trait |
male |
112.0 days
| 5 |
25.4 |
g/d |
1.2 |
2.68 |
unspecified method |
0.0 |
|
|
|
|
|
|
67662 |
735 |
| SS/HsdMcwiCrl |
tibia length |
controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
tibia length |
male |
112.0 days
| 9 |
4.26 |
cm |
0.02 |
0.06 |
unspecified method |
0.0 |
|
|
|
|
|
|
67611 |
735 |
| SS/JrTol |
urine pH |
control condition (for 140 days) |
Garrett MR, et al., Physiol Genomics. 2007 May 15;. |
urine pH trait |
male |
140.0 days
| 6 |
6.6 |
null |
0.07 |
0.17 |
unspecified method |
0.0 |
|
|
|
|
|
|
68016 |
834 |
| Crlj:WI |
brain campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain campesterol amount |
not specified |
77.0 days
| 2 |
0.02 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70529 |
1300 |
| SHR/NCrl |
brain campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain campesterol amount |
not specified |
77.0 days
| 2 |
0.02 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70531 |
1300 |
| Crl:SD |
plasma sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood sitosterol amount |
not specified |
77.0 days
| 2 |
1.95 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70532 |
1300 |
| Crl:SD |
brain sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain sitosterol amount |
not specified |
77.0 days
| 2 |
0.02 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70541 |
1300 |
| SHR/NCrl |
plasma sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood sitosterol amount |
not specified |
77.0 days
| 2 |
6.25 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70535 |
1300 |
| SS/JrHsdMcwi |
urine sodium excretion rate |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
92.0 days-94.0 days |
14 |
0.56 |
mEq/d |
0.06 |
0.21 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
umol/min |
|
69469 |
151 |
| SS/JrHsdMcwi |
urine potassium excretion rate |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine potassium amount |
female |
92.0 days-94.0 days |
14 |
0.92 |
mEq/d |
0.07 |
0.27 |
unspecified method |
0.0 |
|
|
|
urine potassium analysis |
umol/min |
|
69474 |
151 |
| GH |
plasma campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood campesterol amount |
not specified |
77.0 days
| 4 |
2.24 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
plasma campesterol measurement test |
|
|
70519 |
1300 |
| WKY/NCrlCrlj |
plasma phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood phytosterol amount |
not specified |
77.0 days
| 2 |
13.1 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70547 |
1300 |
| GH |
plasma phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood phytosterol amount |
not specified |
77.0 days
| 4 |
4.9 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70549 |
1300 |
| SHR/NCrl |
plasma phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood phytosterol amount |
not specified |
77.0 days
| 2 |
10.3 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70548 |
1300 |
| SHR/NCrl |
liver phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver phytosterol amount |
not specified |
77.0 days
| 2 |
0.21 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70553 |
1300 |
| WKY/NCrlCrlj |
liver phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver phytosterol amount |
not specified |
77.0 days
| 2 |
0.24 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70552 |
1300 |
| WKY/NCrlCrlj |
brain phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain phytosterol amount |
not specified |
77.0 days
| 2 |
0.05 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70556 |
1300 |
| WKY/NCrlCrlj |
brain sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain sitosterol amount |
not specified |
77.0 days
| 2 |
0.03 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70543 |
1300 |
| BN/NHsdMcwi |
urine sodium level |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
89.0 days-92.0 days |
24 |
370.0 |
mmol/l |
14.3 |
70.06 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
|
|
69453 |
151 |
| BN/NHsdMcwi |
urine potassium excretion rate |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine potassium amount |
female |
89.0 days-92.0 days |
24 |
0.96 |
mEq/d |
0.04 |
0.21 |
unspecified method |
0.0 |
|
|
|
urine potassium analysis |
|
|
69461 |
151 |
| Crl:SD |
plasma total cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood cholesterol amount |
not specified |
77.0 days
| 2 |
54.6 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70158 |
1300 |
| Crl:SD |
liver cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver cholesterol amount |
not specified |
77.0 days
| 2 |
1.72 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue total cholesterol analysis |
|
|
70163 |
1300 |
| Crlj:WI |
liver cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver cholesterol amount |
not specified |
77.0 days
| 2 |
1.55 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue total cholesterol analysis |
|
|
70164 |
1300 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (300 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
24.5 |
g/d |
0.57 |
1.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
85465 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (500 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
25.7 |
g/d |
0.28 |
0.8 |
unspecified method |
0.0 |
|
|
|
|
|
|
85466 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (300 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
24.6 |
g/d |
0.21 |
0.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
85471 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
16.6 |
g/d |
0.95 |
2.7 |
unspecified method |
0.0 |
|
|
|
|
|
|
85487 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
4.37 |
g/d/100g |
0.23 |
0.66 |
unspecified method |
0.0 |
|
|
|
|
on days 74-77 |
|
85510 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
6.04 |
g/d/100g |
0.23 |
0.66 |
unspecified method |
0.0 |
|
|
|
|
on days 11-14 |
|
85493 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
18.2 |
g/d |
1.13 |
3.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
85468 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
4.09 |
g/d/100g |
0.45 |
1.28 |
unspecified method |
0.0 |
|
|
|
|
on days 74-77 |
|
85507 |
1604 |
| Crl:CD(SD) |
liver wet weight |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (500 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver mass |
male |
170.0 days
| 8 |
12.8 |
g |
0.22 |
0.61 |
unspecified method |
0.0 |
|
|
|
|
|
|
85559 |
1604 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (40 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
17.2 |
% |
0.6 |
1.59 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96874 |
1719 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (100 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
9.4 |
% |
0.5 |
1.32 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96877 |
1719 |
| Crl:SD |
metformin drink intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
42.0 days
| 8 |
31.0 |
ml/d |
0.3 |
0.85 |
unspecified method |
0.0 |
|
|
|
|
metformin drink intake rate |
|
75870 |
1540 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days
| 12 |
21.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75724 |
1538 |
| Crl:SD |
food intake rate |
controlled ethanol content drinking water (1 %) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days
| 12 |
10.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75717 |
1538 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
8.7 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75741 |
1538 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days
| 12 |
10.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75719 |
1538 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days
| 12 |
20.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75723 |
1538 |
| Crl:SD |
food intake rate |
controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
10.2 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75737 |
1538 |
| BluHsd:LE |
total food calorie intake rate |
controlled in utero environment (for 9 days) and bisphenol A (2.5 ug/kg) (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
2023.0 |
kcal/d |
41.3 |
116.81 |
unspecified method |
0.0 |
|
|
|
|
|
|
76175 |
1543 |
| CrljJcl:SD |
food intake rate |
gestation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 6 |
25.42 |
g/d |
2.18 |
5.34 |
unspecified method |
0.0 |
|
|
|
|
|
|
75762 |
1539 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
105.0 days
| 12 |
7.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75735 |
1538 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
28.1 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75731 |
1538 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
24.7 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75746 |
1538 |
| F344/NHsd |
serum alanine aminotransferase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alanine transaminase amount |
male |
132.0 days-264.0 days |
9 |
55.0 |
U/l |
3.4 |
10.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
84711 |
1599 |
| F344/NHsd |
serum alanine aminotransferase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alanine transaminase amount |
male |
579.0 days-945.0 days |
9 |
54.5 |
U/l |
6.4 |
19.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
84713 |
1599 |
| F344/NHsd |
serum aspartate aminotransferase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood aspartate transaminase amount |
male |
714.0 days-882.0 days |
5 |
194.6 |
U/l |
29.1 |
65.07 |
unspecified method |
0.0 |
|
|
|
|
|
|
84718 |
1599 |
| F344/NHsd |
serum alkaline phosphatase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alkaline phosphatase amount |
male |
123.0 days-267.0 days |
7 |
85.3 |
U/l |
9.9 |
26.19 |
unspecified method |
0.0 |
|
|
|
|
|
|
84720 |
1599 |
| F344/NHsd |
serum alkaline phosphatase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alkaline phosphatase amount |
male |
579.0 days-945.0 days |
9 |
71.6 |
U/l |
9.4 |
28.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
84721 |
1599 |
| F344/NHsd |
serum gamma-glutamyltransferase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood gamma-glutamyltransferase amount |
male |
132.0 days-264.0 days |
9 |
1.2 |
U/l |
0.1 |
0.3 |
unspecified method |
0.0 |
|
|
|
|
|
|
84723 |
1599 |
| F344/NHsd |
serum gamma-glutamyltransferase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood gamma-glutamyltransferase amount |
male |
579.0 days-945.0 days |
9 |
2.1 |
U/l |
0.9 |
2.7 |
unspecified method |
0.0 |
|
|
|
|
|
|
84725 |
1599 |
| F344/NHsd |
serum total protein level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood total protein amount |
male |
132.0 days-264.0 days |
9 |
623.0 |
g/dl |
8.0 |
24.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
84727 |
1599 |
| F344/NHsd |
serum total bilirubin level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood bilirubin amount |
male |
123.0 days-267.0 days |
8 |
7.6 |
mg/dl |
1.17 |
3.31 |
unspecified method |
0.0 |
|
|
|
|
|
|
84736 |
1599 |
| F344/NHsd |
serum creatinine level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood creatinine amount |
male |
714.0 days-882.0 days |
5 |
0.74 |
mg/dl |
0.09 |
0.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
84742 |
1599 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50.0 days-64.0 days |
6 |
33.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84832 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57.0 days-71.0 days |
6 |
35.1 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84837 |
1602 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57.0 days-71.0 days |
6 |
21.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84857 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57.0 days-71.0 days |
6 |
21.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84865 |
1602 |
| SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
8.31 |
x 10E6 cells/ul |
0.22 |
0.53 |
unspecified method |
0.0 |
|
|
|
|
|
|
84894 |
1602 |
| SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71.0 days-85.0 days |
6 |
13.8 |
g/dl |
0.16 |
0.38 |
unspecified method |
0.0 |
|
|
|
|
|
|
84939 |
1602 |
| BluHsd:LE |
food intake weight to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (25 ug/kg) (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
4.7 |
g/g |
0.2 |
0.57 |
unspecified method |
0.0 |
|
|
|
|
|
|
76195 |
1543 |
| LOU/MBbb |
aorta wall extracellular elastin dry weight to aorta wall dry weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
female |
120.0 days-126.0 days |
6 |
37.9 |
% |
0.33 |
0.8 |
unspecified method |
0.0 |
|
|
|
|
elastin to wt ratio |
|
96781 |
1680 |
| LOU/MBbb |
aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
male |
120.0 days-126.0 days |
6 |
1.58 |
null |
0.06 |
0.15 |
unspecified method |
0.0 |
|
|
|
|
elastin/collagen ratio |
|
96784 |
1680 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 24 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
99.93 |
ml/d |
6.84 |
19.35 |
unspecified method |
0.0 |
|
|
|
|
|
|
75889 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
135.87 |
ml/d |
7.74 |
21.89 |
unspecified method |
0.0 |
|
|
|
|
|
|
75895 |
1539 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled ethanol content drinking water (1 %) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days
| 12 |
10.1 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75718 |
1538 |
| Crl:SD |
fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled ethanol content drinking water (1 %) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days
| 12 |
20.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75722 |
1538 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
105.0 days
| 12 |
7.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75736 |
1538 |
| W/Nin |
plasma retinol level |
controlled retinyl palmitate content diet (26 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
28.0 |
ug/dl |
1.3 |
3.18 |
unspecified method |
0.0 |
|
|
|
|
|
|
96742 |
1660 |
| W-LeprfaNin |
plasma retinol level |
controlled retinyl palmitate content diet (129 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
43.0 |
ug/dl |
5.7 |
13.96 |
unspecified method |
0.0 |
|
|
|
|
|
|
96748 |
1660 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
8.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75740 |
1538 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
70.0 days
| 15 |
67.75 |
% |
2.22 |
8.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
76011 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
70.0 days
| 15 |
69.34 |
% |
1.95 |
7.55 |
unspecified method |
0.0 |
|
|
|
|
|
|
76015 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
70.0 days
| 15 |
42.5 |
ml/d |
1.99 |
7.71 |
unspecified method |
0.0 |
|
|
|
|
|
|
76008 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 15 |
47.97 |
% |
1.02 |
3.95 |
unspecified method |
0.0 |
|
|
|
|
|
|
76019 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
37.3 |
% |
1.76 |
7.04 |
unspecified method |
0.0 |
|
|
|
|
|
|
76022 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
60.6 |
% |
2.32 |
9.28 |
unspecified method |
0.0 |
|
|
|
|
|
|
76027 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
23.7 |
% |
1.45 |
5.8 |
unspecified method |
0.0 |
|
|
|
|
|
|
76032 |
1539 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70.0 days-84.0 days |
6 |
27.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84843 |
1602 |
| Crl:SD |
food calorie intake rate |
controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
28.9 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
food energy intake |
|
76105 |
1538 |
| Crl:SD |
total calorie intake rate |
controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
consumption behavior trait |
female |
42.0 days-105.0 days |
12 |
28.9 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
total energy intake |
|
76110 |
1538 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 6 |
56.55 |
g/d |
4.72 |
11.56 |
unspecified method |
0.0 |
|
|
|
|
|
|
75765 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 14 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 3 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
24.35 |
g/d |
2.26 |
6.39 |
unspecified method |
0.0 |
|
|
|
|
|
|
75802 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 20 days) then controlled bisphenol A content drinking water (1 mg/l) (for 9 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
21.91 |
g/d |
2.15 |
6.08 |
unspecified method |
0.0 |
|
|
|
|
|
|
75807 |
1539 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50.0 days-64.0 days |
6 |
21.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84860 |
1602 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 19 |
4.18 |
g/d/100g |
0.19 |
0.84 |
unspecified method |
0.0 |
|
|
|
|
|
|
85307 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 19 |
6.11 |
g/d/100g |
0.1 |
0.45 |
unspecified method |
0.0 |
|
|
|
|
|
|
85301 |
1604 |
| Crl:CD(SD) |
liver wet weight |
standard diet and restricted feeding (4 h) (for 114 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver mass |
male |
170.0 days
| 19 |
11.09 |
g |
0.16 |
0.71 |
unspecified method |
0.0 |
|
|
|
|
|
|
85403 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
16.7 |
g/d |
0.95 |
2.7 |
unspecified method |
0.0 |
|
|
|
|
|
|
85469 |
1604 |
| F344/NHsd |
serum aspartate aminotransferase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood aspartate transaminase amount |
male |
132.0 days-264.0 days |
9 |
112.4 |
U/l |
11.3 |
33.9 |
unspecified method |
0.0 |
|
|
|
|
|
|
84715 |
1599 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70.0 days-84.0 days |
6 |
31.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84827 |
1602 |
| SD |
red blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
8.61 |
x 10E6 cells/ul |
0.22 |
0.54 |
unspecified method |
0.0 |
|
|
|
|
|
|
84909 |
1602 |
| SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
85.0 days-99.0 days |
6 |
8.68 |
x 1000 cells/ul |
1.91 |
4.68 |
unspecified method |
0.0 |
|
|
|
|
|
|
84907 |
1602 |
| SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85.0 days-99.0 days |
6 |
39.8 |
% |
0.63 |
1.55 |
unspecified method |
0.0 |
|
|
|
|
|
|
84961 |
1602 |
| HanTac:WH |
number of blastocysts/embryos lost postimplantation to litter size ratio |
bisphenol A (50 mg/kg/d) (for 14 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
embryonic growth trait |
female |
days
| 18 |
13.0 |
% |
5.14 |
21.8 |
unspecified method |
0.0 |
|
|
|
|
|
|
96591 |
1559 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (60 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
12.1 |
% |
0.5 |
1.12 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96883 |
1719 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (40 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
15.7 |
% |
0.5 |
1.73 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96890 |
1719 |
| Hsd:WI |
serum superoxide dismutase activity level |
acetaminophen (500 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood superoxide dismutase amount |
not specified |
days
| 10 |
7.9 |
U/l |
0.35 |
1.1 |
unspecified method |
0.0 |
|
|
|
|
|
|
85608 |
1618 |
| Hsd:WI |
serum superoxide dismutase activity level |
fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood superoxide dismutase amount |
not specified |
days
| 10 |
5.5 |
U/l |
0.16 |
0.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
85606 |
1618 |
| Hsd:WI |
serum superoxide dismutase activity level |
acetaminophen (500 mg/kg) (for 1 days) then thymoquinone (15 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood superoxide dismutase amount |
not specified |
days
| 10 |
5.7 |
U/l |
1.71 |
5.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
85609 |
1618 |
| Crl:SD |
food intake rate |
controlled fructose content diet (66 %) (between 14 and 28 days) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
63.0 days-77.0 days |
9 |
26.0 |
g/d |
1.7 |
5.1 |
unspecified method |
0.0 |
|
|
|
|
F |
|
75871 |
1540 |
| Crl:SD |
food intake rate |
control condition |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
63.0 days-77.0 days |
8 |
28.0 |
g/d |
0.9 |
2.55 |
unspecified method |
0.0 |
|
|
|
|
C |
|
75872 |
1540 |
| Crl:SD |
food intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
42.0 days
| 10 |
18.0 |
g/d |
0.3 |
0.95 |
unspecified method |
0.0 |
|
|
|
|
FT |
|
75877 |
1540 |
| CrljJcl:SD |
water drink intake rate |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
70.0 days
| 15 |
29.43 |
ml/d |
2.41 |
9.33 |
unspecified method |
0.0 |
|
|
|
|
|
|
75990 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
140.0 days
| 15 |
14.16 |
ml/d |
0.88 |
3.41 |
unspecified method |
0.0 |
|
|
|
|
|
|
75988 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
140.0 days
| 15 |
5.86 |
ml/d |
1.33 |
5.15 |
unspecified method |
0.0 |
|
|
|
|
|
|
75994 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
70.0 days
| 15 |
22.3 |
ml/d |
1.12 |
4.34 |
unspecified method |
0.0 |
|
|
|
|
|
|
75996 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
140.0 days
| 15 |
50.54 |
ml/d |
3.17 |
12.28 |
unspecified method |
0.0 |
|
|
|
|
|
|
76000 |
1539 |
| SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71.0 days-85.0 days |
6 |
6.56 |
x 1000 cells/ul |
0.4 |
0.97 |
unspecified method |
0.0 |
|
|
|
|
|
|
84885 |
1602 |
| SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
85.0 days-99.0 days |
6 |
8.34 |
x 1000 cells/ul |
0.79 |
1.94 |
unspecified method |
0.0 |
|
|
|
|
|
|
84893 |
1602 |
| SD |
blood hemoglobin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71.0 days-85.0 days |
6 |
13.68 |
g/dl |
0.17 |
0.41 |
unspecified method |
0.0 |
|
|
|
|
|
|
84941 |
1602 |
| SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71.0 days-85.0 days |
6 |
13.98 |
g/dl |
0.2 |
0.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
84942 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
85.0 days-99.0 days |
6 |
11.73 |
% |
0.18 |
0.44 |
unspecified method |
0.0 |
|
|
|
|
|
|
84968 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
85.0 days-99.0 days |
6 |
11.35 |
% |
0.16 |
0.38 |
unspecified method |
0.0 |
|
|
|
|
|
|
84974 |
1602 |
| SD |
platelet count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71.0 days-85.0 days |
6 |
1148.83 |
x 1000 /ul |
114.06 |
279.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
84976 |
1602 |
| SD |
platelet count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71.0 days-85.0 days |
6 |
1177.5 |
x 1000 /ul |
83.55 |
204.66 |
unspecified method |
0.0 |
|
|
|
|
|
|
84977 |
1602 |
| SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
85.0 days-99.0 days |
6 |
846.0 |
x 1000 /ul |
35.44 |
86.81 |
unspecified method |
0.0 |
|
|
|
|
|
|
84985 |
1602 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (160 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
7.6 |
% |
0.4 |
1.06 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96880 |
1719 |
| CrljJcl:SD |
food intake rate |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
42.0 days
| 15 |
12.32 |
g/d |
2.49 |
9.64 |
unspecified method |
0.0 |
|
|
|
|
|
|
75936 |
1539 |
| CrljJcl:SD |
food intake rate |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
male |
140.0 days
| 15 |
28.12 |
g/d |
3.05 |
11.81 |
unspecified method |
0.0 |
|
|
|
|
|
|
75935 |
1539 |
| Y59/Zgd |
bone ash content |
ethanol (0.5 %) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.63 |
g |
0.02 |
0.06 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97411 |
1758 |
| SS-Renem1Mcwi+/+ |
creatinine clearance to total kidney weight ratio |
controlled sodium content diet (0.4 %) (for 42 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
glomerular filtration trait |
female |
63.0 days
| 8 |
0.87 |
ml/min/g |
0.1 |
0.28 |
unspecified method |
0.0 |
|
|
|
|
|
|
98352 |
2038 |
| F344 |
mean arterial blood pressure |
sucrose (10 %) (for 1 hours) |
Westlund KN, et al., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3. |
arterial blood pressure trait |
male |
days
| 2 |
127.7 |
mmHg |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
105572 |
3018 |
| SHRSP/A3N |
ratio of deaths related to chronic hypertension to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 63 days) and controlled fat content diet (24.5 %) (for 63 days) and vehicle control condition (for 63 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
total life span |
male |
147.0 days-168.0 days |
25 |
95.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to chronic hypertension to total study population during a period of time (CMO:0003800) |
|
107518 |
3090 |
| SHRSP/A3N |
ratio of deaths related to chronic hypertension to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 84 days) and controlled fat content diet (24.5 %) (for 84 days) and eprosartan (60 mg/kg/d) (for 84 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
total life span |
male |
168.0 days-189.0 days |
25 |
0.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to chronic hypertension to total study population during a period of time (CMO:0003800) |
|
107519 |
3090 |
| WAG/Nov |
systolic blood pressure |
control condition |
Shurligina AV, et al., Bull Exp Biol Med. 2013 Aug;155(4):421-4. doi: 10.1007/s10517-013-2167-4. |
arterial blood pressure trait |
male |
150.0 days-180.0 days |
10 |
125.0 |
mmHg |
10.2 |
32.26 |
unspecified method |
0.0 |
|
|
|
|
|
|
107670 |
3096 |
| ISIAH |
gestation period length |
control condition |
Ragaeva DS, et al., Physiol Behav. 2017 Jun 1;175:22-30. doi: 10.1016/j.physbeh.2017.03.026. Epub 2017 Mar 21. |
gestation period duration |
female |
98.0 days-112.0 days |
5 |
22.0 |
d |
0.0 |
0.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
110679 |
3182 |
| SHRSP/A3N |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
standard condition (for 126 days) |
Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. |
total life span |
male |
203.0 days-224.0 days |
20 |
0.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107114 |
3075 |
| SHRSP/A3NCrl |
ratio of survivors of severe albuminuria to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 91 days) and controlled fat content diet (24.5 %) (for 91 days) then vehicle control condition (for 35 days) |
Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. |
life span trait |
male |
161.0 days-175.0 days |
12 |
50.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of survivors of severe albuminuria to total study population during a period of time (CMO:0003630) |
|
109030 |
3083 |
| SPRD/Ztm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) (for 133 days) |
Piessevaux G, et al., Mamm Genome. 2008 Dec 4 |
mammary gland integrity trait |
female |
days
| 25 |
0.72 |
cm/week |
0.04 |
0.2 |
unspecified method |
0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11509 |
74 |
| SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) (for 133 days) |
Piessevaux G, et al., Mamm Genome. 2008 Dec 4 |
mammary gland integrity trait |
female |
days
| 16 |
0.65 |
cm/week |
0.08 |
0.32 |
unspecified method |
0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11510 |
74 |
| SPRD.WKY-(D18Wox8-D18Rat44)/Ibmm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) (for 133 days) |
Piessevaux G, et al., Mamm Genome. 2008 Dec 4 |
mammary gland integrity trait |
female |
days
| 52 |
0.73 |
cm/week |
0.03 |
0.22 |
unspecified method |
0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11511 |
74 |
| SS/HsdMcwiCrl |
water drink intake rate |
controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
drinking behavior trait |
male |
112.0 days
| 8 |
30.1 |
ml/d |
1.8 |
5.09 |
unspecified method |
0.0 |
|
|
|
|
|
|
67663 |
735 |
| SS/HsdMcwiCrl |
water drink intake rate |
controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
drinking behavior trait |
male |
112.0 days
| 7 |
18.4 |
ml/d |
2.4 |
6.35 |
unspecified method |
0.0 |
|
|
|
|
|
|
67665 |
735 |
| SS/HsdMcwiCrl |
water drink intake rate |
controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
drinking behavior trait |
male |
112.0 days
| 9 |
21.8 |
ml/d |
1.6 |
4.8 |
unspecified method |
0.0 |
|
|
|
|
|
|
67664 |
735 |
| WKY/NCrlCrlj |
plasma sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood sitosterol amount |
not specified |
77.0 days
| 2 |
8.65 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70534 |
1300 |
| SS/JrHsdMcwi |
urine sodium level |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
92.0 days-94.0 days |
14 |
149.5 |
mmol/l |
5.2 |
19.46 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
|
|
69467 |
151 |
| BN/NHsdMcwi |
urine potassium excretion rate |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine potassium amount |
female |
92.0 days-94.0 days |
22 |
0.88 |
mEq/d |
0.06 |
0.27 |
unspecified method |
0.0 |
|
|
|
urine potassium analysis |
umol/min |
|
69473 |
151 |
| SHR/NCrl |
liver sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver sitosterol amount |
not specified |
77.0 days
| 2 |
0.12 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70540 |
1300 |
| BN/NHsdMcwi |
plasma total protein level |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
blood total protein amount |
female |
89.0 days-92.0 days |
13 |
38.6 |
mg/ml |
2.0 |
7.21 |
unspecified method |
0.0 |
|
|
|
|
|
|
69483 |
151 |
| Crl:SD |
plasma campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood campesterol amount |
not specified |
77.0 days
| 2 |
1.3 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
plasma campesterol measurement test |
|
|
70515 |
1300 |
| SHR/NCrl |
plasma campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood campesterol amount |
not specified |
77.0 days
| 2 |
4.0 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
plasma campesterol measurement test |
|
|
70518 |
1300 |
| SHR/NCrl |
liver campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver campesterol amount |
not specified |
77.0 days
| 2 |
0.09 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70523 |
1300 |
| SHR/NCrl |
brain phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain phytosterol amount |
not specified |
77.0 days
| 2 |
0.03 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70557 |
1300 |
| SS-Rag1em1Mcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (for 21 days) |
Mattson DL, et al., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30. |
blood creatinine amount |
not specified |
84.0 days
| |
0.25 |
mg/dl |
0.03 |
|
unspecified method |
0.0 |
|
|
|
|
|
|
69285 |
1057 |
| SS/JrHsdMcwi |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 21 days) |
Mattson DL, et al., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30. |
urine albumin amount |
not specified |
84.0 days
| 4 |
127.0 |
mg/d |
17.0 |
34.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
69294 |
1057 |
| WKY/NCrlCrlj |
plasma total cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood cholesterol amount |
not specified |
77.0 days
| 2 |
63.4 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70160 |
1300 |
| SHR/NCrl |
plasma total cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood cholesterol amount |
not specified |
77.0 days
| 2 |
58.3 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70161 |
1300 |
| CrljJcl:SD |
food intake rate |
gestation (for 20 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 6 |
22.08 |
g/d |
1.97 |
4.83 |
unspecified method |
0.0 |
|
|
|
|
|
|
75763 |
1539 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 19 |
17.0 |
g/d |
0.73 |
3.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
85292 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 19 |
17.2 |
g/d |
0.83 |
3.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
85299 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (500 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
22.8 |
g/d |
0.71 |
2.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
85484 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
5.68 |
g/d/100g |
0.06 |
0.17 |
unspecified method |
0.0 |
|
|
|
|
on days 11-14 |
|
85490 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
5.12 |
g/d/100g |
0.15 |
0.42 |
unspecified method |
0.0 |
|
|
|
|
on days 32-35 |
|
85496 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
5.09 |
g/d/100g |
0.24 |
0.67 |
unspecified method |
0.0 |
|
|
|
|
on days 32-35 |
|
85498 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
4.7 |
g/d/100g |
0.06 |
0.17 |
unspecified method |
0.0 |
|
|
|
|
on days 53-56 |
|
85501 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
4.38 |
g/d/100g |
0.31 |
0.87 |
unspecified method |
0.0 |
|
|
|
|
on days 53-56 |
|
85504 |
1604 |
| Crl:SD |
water drink intake rate |
controlled fructose content diet (66 %) (between 14 and 28 days) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
63.0 days-77.0 days |
9 |
39.0 |
ml/d |
0.7 |
2.1 |
unspecified method |
0.0 |
|
|
|
|
F |
|
75863 |
1540 |
| Crl:SD |
metformin drink intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
63.0 days-77.0 days |
10 |
35.0 |
ml/d |
0.4 |
1.26 |
unspecified method |
0.0 |
|
|
|
|
metformin drink intake rate |
|
75865 |
1540 |
| Crl:SD |
ethanol drink intake rate |
controlled ethanol content drinking water (1 %) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
11.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75729 |
1538 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
105.0 days
| 12 |
29.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75745 |
1538 |
| BluHsd:LE |
food calorie intake level to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (2.5 ug/kg) (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
10.4 |
kcal/g |
0.5 |
1.41 |
unspecified method |
0.0 |
|
|
|
|
|
|
76196 |
1543 |
| F344/NHsd |
serum alanine aminotransferase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alanine transaminase amount |
male |
714.0 days-882.0 days |
5 |
51.0 |
U/l |
8.0 |
17.89 |
unspecified method |
0.0 |
|
|
|
|
|
|
84714 |
1599 |
| F344/NHsd |
serum gamma-glutamyltransferase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood gamma-glutamyltransferase amount |
male |
714.0 days-882.0 days |
5 |
1.2 |
U/l |
0.2 |
0.45 |
unspecified method |
0.0 |
|
|
|
|
|
|
84726 |
1599 |
| F344/NHsd |
serum albumin level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood albumin amount |
male |
132.0 days-264.0 days |
9 |
136.0 |
g/dl |
3.0 |
9.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
84731 |
1599 |
| F344/NHsd |
serum albumin level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood albumin amount |
male |
579.0 days-945.0 days |
9 |
104.0 |
g/dl |
10.0 |
30.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
84733 |
1599 |
| F344/NHsd |
serum total bilirubin level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood bilirubin amount |
male |
132.0 days-264.0 days |
9 |
5.85 |
mg/dl |
1.17 |
3.51 |
unspecified method |
0.0 |
|
|
|
|
|
|
84735 |
1599 |
| F344/NHsd |
serum creatinine level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood creatinine amount |
male |
579.0 days-945.0 days |
7 |
0.37 |
mg/dl |
0.05 |
0.13 |
unspecified method |
0.0 |
|
|
|
|
|
|
84741 |
1599 |
| F344/NHsd |
serum creatinine level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood creatinine amount |
male |
123.0 days-267.0 days |
6 |
0.47 |
mg/dl |
0.02 |
0.06 |
unspecified method |
0.0 |
|
|
|
|
|
|
84740 |
1599 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50.0 days-64.0 days |
6 |
33.1 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84824 |
1602 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70.0 days-84.0 days |
6 |
31.7 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84835 |
1602 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70.0 days-84.0 days |
6 |
26.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84855 |
1602 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64.0 days-78.0 days |
6 |
23.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84854 |
1602 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64.0 days-78.0 days |
6 |
21.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84858 |
1602 |
| SD |
red blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
8.56 |
x 10E6 cells/ul |
0.2 |
0.49 |
unspecified method |
0.0 |
|
|
|
|
|
|
84895 |
1602 |
| SD |
blood hemoglobin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
71.0 days-85.0 days |
6 |
14.02 |
g/dl |
0.28 |
0.69 |
unspecified method |
0.0 |
|
|
|
|
|
|
84940 |
1602 |
| SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
85.0 days-99.0 days |
6 |
12.38 |
g/dl |
0.36 |
0.88 |
unspecified method |
0.0 |
|
|
|
|
|
|
84950 |
1602 |
| BN/Rj |
aorta wall extracellular elastin dry weight to aorta wall dry weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
female |
120.0 days-126.0 days |
6 |
31.8 |
% |
0.61 |
1.5 |
unspecified method |
0.0 |
|
|
|
|
elastin to wt ratio |
|
96779 |
1680 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 14 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 3 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
44.96 |
ml/d |
4.73 |
13.38 |
unspecified method |
0.0 |
|
|
|
|
|
|
75891 |
1539 |
| W/Nin |
plasma retinol level |
controlled retinyl palmitate content diet (2.6 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
28.0 |
ug/dl |
1.4 |
3.43 |
unspecified method |
0.0 |
|
|
|
|
|
|
96741 |
1660 |
| W-LeprfaNin |
plasma retinol level |
controlled retinyl palmitate content diet (26 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
41.0 |
ug/dl |
2.5 |
6.12 |
unspecified method |
0.0 |
|
|
|
|
|
|
96746 |
1660 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days
| 12 |
9.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75742 |
1538 |
| CrljJcl:SD |
food intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
70.0 days
| 15 |
12.17 |
g/d |
1.88 |
7.28 |
unspecified method |
0.0 |
|
|
|
|
|
|
75984 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
140.0 days
| 15 |
78.12 |
% |
3.22 |
12.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
76012 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
140.0 days
| 15 |
86.83 |
% |
3.12 |
12.08 |
unspecified method |
0.0 |
|
|
|
|
|
|
76014 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 15 |
55.38 |
% |
1.67 |
6.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
76013 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 15 |
51.68 |
% |
1.44 |
5.58 |
unspecified method |
0.0 |
|
|
|
|
|
|
76016 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
70.0 days
| 15 |
65.59 |
% |
2.86 |
11.08 |
unspecified method |
0.0 |
|
|
|
|
|
|
76020 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
43.3 |
% |
2.08 |
8.32 |
unspecified method |
0.0 |
|
|
|
|
|
|
76026 |
1539 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50.0 days-64.0 days |
6 |
33.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84840 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50.0 days-64.0 days |
6 |
39.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84844 |
1602 |
| Crl:SD |
fructose drink calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
5.7 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
fructose energy intake |
|
76101 |
1538 |
| Crl:SD |
food calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
23.5 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
food energy intake |
|
76108 |
1538 |
| Crl:SD |
total calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
consumption behavior trait |
female |
42.0 days-105.0 days |
12 |
30.3 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
total energy intake |
|
76111 |
1538 |
| BluHsd:LE |
food calorie intake level to change in body weight ratio |
controlled in utero environment (for 9 days) and vehicle control condition (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
10.4 |
kcal/g |
0.3 |
0.85 |
unspecified method |
0.0 |
|
|
|
|
|
|
76198 |
1543 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (1 mg/l) (for 24 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
54.38 |
g/d |
5.41 |
15.3 |
unspecified method |
0.0 |
|
|
|
|
|
|
75810 |
1539 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64.0 days-78.0 days |
6 |
39.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84846 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57.0 days-71.0 days |
6 |
21.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84849 |
1602 |
| Crl:CD(SD) |
food intake rate |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 19 |
24.5 |
g/d |
0.37 |
1.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
85291 |
1604 |
| Crl:CD(SD) |
liver wet weight |
standard diet and restricted feeding (4 h) (for 114 days) then acetaminophen (300 mg/kg) (for 99 days) then fasting (for 20 hours) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver mass |
male |
170.0 days
| 8 |
12.2 |
g |
0.77 |
2.17 |
unspecified method |
0.0 |
|
|
|
|
|
|
85558 |
1604 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50.0 days-64.0 days |
6 |
32.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84828 |
1602 |
| SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
8.64 |
x 10E6 cells/ul |
0.16 |
0.39 |
unspecified method |
0.0 |
|
|
|
|
|
|
84897 |
1602 |
| SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
8.26 |
x 10E6 cells/ul |
0.24 |
0.59 |
unspecified method |
0.0 |
|
|
|
|
|
|
84908 |
1602 |
| SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85.0 days-99.0 days |
6 |
45.68 |
% |
0.45 |
1.11 |
unspecified method |
0.0 |
|
|
|
|
|
|
84955 |
1602 |
| SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
41.03 |
% |
1.15 |
2.81 |
unspecified method |
0.0 |
|
|
|
|
|
|
84957 |
1602 |
| SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
41.85 |
% |
0.63 |
1.55 |
unspecified method |
0.0 |
|
|
|
|
|
|
84960 |
1602 |
| SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85.0 days-99.0 days |
6 |
41.5 |
% |
0.64 |
1.57 |
unspecified method |
0.0 |
|
|
|
|
|
|
84962 |
1602 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (140 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
7.8 |
% |
0.4 |
1.06 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96879 |
1719 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (40 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
15.6 |
% |
0.5 |
1.12 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96882 |
1719 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (160 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
7.3 |
% |
0.3 |
1.04 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96896 |
1719 |
| CrljJcl:SD |
food intake rate |
gestation (for 20 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 9 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
23.8 |
g/d |
1.65 |
4.67 |
unspecified method |
0.0 |
|
|
|
|
|
|
75768 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 17 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
44.7 |
g/d |
3.28 |
9.28 |
unspecified method |
0.0 |
|
|
|
|
|
|
75769 |
1539 |
| CrljJcl:SD |
food intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
male |
70.0 days
| 15 |
22.77 |
g/d |
3.64 |
14.1 |
unspecified method |
0.0 |
|
|
|
|
|
|
75981 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
70.0 days
| 15 |
66.57 |
ml/d |
4.03 |
15.61 |
unspecified method |
0.0 |
|
|
|
|
|
|
76002 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
140.0 days
| 15 |
62.92 |
ml/d |
4.28 |
16.58 |
unspecified method |
0.0 |
|
|
|
|
|
|
76003 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
140.0 days
| 15 |
45.0 |
ml/d |
2.32 |
8.99 |
unspecified method |
0.0 |
|
|
|
|
|
|
76009 |
1539 |
| SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
85.0 days-99.0 days |
6 |
8.19 |
x 1000 cells/ul |
0.53 |
1.31 |
unspecified method |
0.0 |
|
|
|
|
|
|
84891 |
1602 |
| SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
85.0 days-99.0 days |
6 |
13.9 |
g/dl |
0.2 |
0.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
84943 |
1602 |
| SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
85.0 days-99.0 days |
6 |
11.02 |
g/dl |
0.23 |
0.57 |
unspecified method |
0.0 |
|
|
|
|
|
|
84949 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71.0 days-85.0 days |
6 |
10.98 |
% |
0.32 |
0.78 |
unspecified method |
0.0 |
|
|
|
|
|
|
84969 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71.0 days-85.0 days |
6 |
12.62 |
% |
0.32 |
0.79 |
unspecified method |
0.0 |
|
|
|
|
|
|
84971 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71.0 days-85.0 days |
6 |
11.13 |
% |
0.35 |
0.85 |
unspecified method |
0.0 |
|
|
|
|
|
|
84972 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
85.0 days-99.0 days |
6 |
11.32 |
% |
0.24 |
0.59 |
unspecified method |
0.0 |
|
|
|
|
|
|
84973 |
1602 |
| SD |
platelet count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71.0 days-85.0 days |
6 |
919.0 |
x 1000 /ul |
33.89 |
83.02 |
unspecified method |
0.0 |
|
|
|
|
|
|
84983 |
1602 |
| SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
85.0 days-99.0 days |
6 |
1171.0 |
x 1000 /ul |
54.19 |
132.73 |
unspecified method |
0.0 |
|
|
|
|
|
|
84979 |
1602 |
| SD |
platelet count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71.0 days-85.0 days |
6 |
855.83 |
x 1000 /ul |
38.39 |
94.03 |
unspecified method |
0.0 |
|
|
|
|
|
|
84982 |
1602 |
| SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71.0 days-85.0 days |
6 |
1025.83 |
x 1000 /ul |
20.16 |
49.39 |
unspecified method |
0.0 |
|
|
|
|
|
|
84984 |
1602 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
4.03 |
g/d/100g |
0.29 |
0.81 |
unspecified method |
0.0 |
|
|
|
|
on days 74-77 |
|
85511 |
1604 |
| CrljJcl:SD |
food intake rate |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
140.0 days
| 15 |
14.04 |
g/d |
1.04 |
4.03 |
unspecified method |
0.0 |
|
|
|
|
|
|
75938 |
1539 |
| W/Nin |
food intake rate |
controlled retinyl palmitate content diet (129 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
18.8 |
g/d |
0.86 |
2.11 |
unspecified method |
0.0 |
|
|
|
|
|
|
96728 |
1660 |
| W-LeprfaNin |
food intake rate |
controlled retinyl palmitate content diet (2.6 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
27.9 |
g/d |
0.82 |
2.01 |
unspecified method |
0.0 |
|
|
|
|
|
|
96729 |
1660 |
| W-LeprfaNin |
food intake rate |
controlled retinyl palmitate content diet (26 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
29.3 |
g/d |
1.06 |
2.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
96730 |
1660 |
| W/Nin |
plasma glucose level |
controlled retinyl palmitate content diet (26 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
99.54 |
mg/dl |
5.76 |
14.11 |
unspecified method |
0.0 |
|
|
|
|
|
|
96734 |
1660 |
| W-LeprfaNin |
plasma glucose level |
controlled retinyl palmitate content diet (52 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
132.12 |
mg/dl |
10.8 |
26.45 |
unspecified method |
0.0 |
|
|
|
|
|
|
96739 |
1660 |
| Y59/Zgd |
bone ash content |
quercetin (100 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.67 |
g |
0.01 |
0.02 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97413 |
1758 |
| Y59/Zgd |
bone ash content |
alendronate (40 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.58 |
g |
0.01 |
0.02 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97412 |
1758 |
| Y59/Zgd |
bone ash content |
vitamin A (80 mg/kg/d) (for 14 days) and chrysin (100 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.75 |
g |
0.03 |
0.09 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97409 |
1758 |
| SD |
food intake rate |
unilateral nephrectomy (for 28 days) then spironolactone (5.56 mg/kg/d) (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
eating behavior trait |
male |
days
| 8 |
23.0 |
g/d |
2.12 |
6.0 |
unspecified method |
0.0 |
unx |
28 |
days |
|
change from surgery weight |
|
101612 |
2602 |
| SS-Renem1Mcwi-/- |
creatinine clearance to total kidney weight ratio |
controlled sodium content diet (0.4 %) (for 42 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
glomerular filtration trait |
female |
63.0 days
| 4 |
0.3 |
ml/min/g |
0.03 |
0.06 |
unspecified method |
0.0 |
|
|
|
|
|
|
98354 |
2038 |
| F344 |
mean arterial blood pressure |
control condition |
Westlund KN, et al., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3. |
arterial blood pressure trait |
male |
days
| 3 |
113.42 |
mmHg |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
105569 |
3018 |
| F344 |
mean arterial blood pressure |
4-methyl-2-(piperidin-1-yl)-quinoline (1 mg/kg) (for 1 hours) |
Westlund KN, et al., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3. |
arterial blood pressure trait |
male |
days
| 3 |
98.16 |
mmHg |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
105573 |
3018 |
| WKY/N |
ratio of deaths related to chronic hypertension to total study population during a period of time |
control condition |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
total life span |
male |
168.0 days-189.0 days |
25 |
0.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to chronic hypertension to total study population during a period of time (CMO:0003800) |
|
107516 |
3090 |
| WAG/Nov |
gestation period length |
control condition |
Ragaeva DS, et al., Physiol Behav. 2017 Jun 1;175:22-30. doi: 10.1016/j.physbeh.2017.03.026. Epub 2017 Mar 21. |
gestation period duration |
female |
98.0 days-112.0 days |
5 |
22.3 |
d |
0.4 |
0.89 |
unspecified method |
0.0 |
|
|
|
|
|
|
110680 |
3182 |
| WKY/NCrl |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
standard condition (for 126 days) |
Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. |
total life span |
male |
203.0 days-224.0 days |
20 |
0.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107115 |
3075 |
| SPRD/Ztm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
97.0 days-118.0 days |
48 |
0.7 |
cm/week |
0.0 |
0.03 |
unspecified method |
0.0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11346 |
73 |
| SS/HsdMcwiCrl |
food intake rate |
controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
eating behavior trait |
male |
112.0 days
| 7 |
20.9 |
g/d |
1.4 |
3.7 |
unspecified method |
0.0 |
|
|
|
|
|
|
67661 |
735 |
| SS/HsdMcwiCrl |
tibia length |
controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
tibia length |
male |
112.0 days
| 7 |
4.24 |
cm |
0.01 |
0.03 |
unspecified method |
0.0 |
|
|
|
|
|
|
67610 |
735 |
| SS/HsdMcwiCrl |
tibia length |
controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
tibia length |
male |
112.0 days
| 8 |
4.34 |
cm |
0.03 |
0.08 |
unspecified method |
0.0 |
|
|
|
|
|
|
67613 |
735 |
| SHR/NHsdMco |
urine pH |
control condition (for 140 days) |
Garrett MR, et al., Physiol Genomics. 2007 May 15;. |
urine pH trait |
male |
140.0 days
| 6 |
7.2 |
null |
0.1 |
0.24 |
unspecified method |
0.0 |
|
|
|
|
|
|
68014 |
834 |
| SS.SHR-(D2Rat61-D2Mco18)/Mco |
urine pH |
control condition (for 140 days) |
Garrett MR, et al., Physiol Genomics. 2007 May 15;. |
urine pH trait |
male |
140.0 days
| 6 |
6.8 |
null |
0.07 |
0.17 |
unspecified method |
0.0 |
|
|
|
|
|
|
68015 |
834 |
| BN/NHsdMcwi |
urine sodium level |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
92.0 days-94.0 days |
22 |
100.4 |
mmol/l |
6.5 |
30.49 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
|
|
69466 |
151 |
| BN/NHsdMcwi |
urine sodium excretion rate |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
92.0 days-94.0 days |
22 |
0.46 |
mEq/d |
0.03 |
0.13 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
umol/min |
|
69468 |
151 |
| BN/NHsdMcwi |
urine potassium level |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine potassium amount |
female |
92.0 days-94.0 days |
22 |
93.4 |
mmol/l |
5.7 |
26.74 |
unspecified method |
0.0 |
|
|
|
urine potassium analysis |
|
|
69471 |
151 |
| Crl:SD |
liver sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver sitosterol amount |
not specified |
77.0 days
| 2 |
0.03 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70537 |
1300 |
| WKY/NCrlCrlj |
liver sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver sitosterol amount |
not specified |
77.0 days
| 2 |
0.14 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70539 |
1300 |
| WKY/NCrlCrlj |
plasma campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood campesterol amount |
not specified |
77.0 days
| 2 |
4.4 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
plasma campesterol measurement test |
|
|
70517 |
1300 |
| Crl:SD |
brain cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain cholesterol amount |
not specified |
77.0 days
| 2 |
10.95 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70524 |
1300 |
| Crlj:WI |
brain cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain cholesterol amount |
not specified |
77.0 days
| 2 |
13.73 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70525 |
1300 |
| SHR/NCrl |
brain sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain sitosterol amount |
not specified |
77.0 days
| 2 |
0.01 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70544 |
1300 |
| Crlj:WI |
liver phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver phytosterol amount |
not specified |
77.0 days
| 2 |
0.08 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70551 |
1300 |
| Crlj:WI |
brain phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain phytosterol amount |
not specified |
77.0 days
| 2 |
0.06 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70555 |
1300 |
| SS/JrHsdMcwi |
urine sodium level |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
89.0 days-92.0 days |
17 |
338.0 |
mmol/l |
29.2 |
120.39 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
|
|
69454 |
151 |
| Crlj:WI |
plasma total cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood cholesterol amount |
not specified |
77.0 days
| 2 |
92.0 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70159 |
1300 |
| GH |
plasma total cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood cholesterol amount |
not specified |
77.0 days
| 4 |
84.0 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70162 |
1300 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 19 |
17.2 |
g/d |
0.6 |
2.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
85293 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 19 |
23.7 |
g/d |
0.48 |
2.1 |
unspecified method |
0.0 |
|
|
|
|
|
|
85298 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 19 |
5.28 |
g/d/100g |
0.06 |
0.24 |
unspecified method |
0.0 |
|
|
|
|
|
|
85302 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 19 |
5.36 |
g/d/100g |
0.15 |
0.65 |
unspecified method |
0.0 |
|
|
|
|
|
|
85303 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 19 |
4.62 |
g/d/100g |
0.13 |
0.56 |
unspecified method |
0.0 |
|
|
|
|
|
|
85305 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 19 |
5.78 |
g/d/100g |
0.1 |
0.42 |
unspecified method |
0.0 |
|
|
|
|
|
|
85300 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 19 |
4.44 |
g/d/100g |
0.06 |
0.28 |
unspecified method |
0.0 |
|
|
|
|
|
|
85306 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (300 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
24.1 |
g/d |
0.53 |
1.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
85459 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
20.3 |
g/d |
1.06 |
3.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
85462 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
17.7 |
g/d |
1.31 |
3.7 |
unspecified method |
0.0 |
|
|
|
|
|
|
85481 |
1604 |
| Crl:CD(SD) |
liver wet weight |
standard diet then acetaminophen (300 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver mass |
male |
170.0 days
| 8 |
20.1 |
g |
0.47 |
1.33 |
unspecified method |
0.0 |
|
|
|
|
liver weight not available |
|
85555 |
1604 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (80 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
10.8 |
% |
0.6 |
1.59 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96876 |
1719 |
| Crl:SD |
water drink intake rate |
controlled fructose content diet (66 %) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
42.0 days
| 9 |
34.0 |
ml/d |
0.3 |
0.9 |
unspecified method |
0.0 |
|
|
|
|
F |
|
75867 |
1540 |
| Crl:SD |
water drink intake rate |
control condition |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
42.0 days
| 8 |
35.0 |
ml/d |
0.7 |
1.98 |
unspecified method |
0.0 |
|
|
|
|
C |
|
75868 |
1540 |
| CrljJcl:SD |
water drink intake rate |
gestation (for 20 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 6 |
59.93 |
ml/d |
4.31 |
10.56 |
unspecified method |
0.0 |
|
|
|
|
|
|
75882 |
1539 |
| Crl:SD |
ethanol drink intake rate |
controlled ethanol content drinking water (1 %) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days
| 12 |
11.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75721 |
1538 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days
| 12 |
9.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75720 |
1538 |
| BluHsd:LE |
total food calorie intake rate |
controlled in utero environment (for 9 days) and bisphenol A (25 ug/kg) (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
1969.2 |
kcal/d |
101.4 |
286.8 |
unspecified method |
0.0 |
|
|
|
|
|
|
76176 |
1543 |
| CrljJcl:SD |
food intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
42.0 days
| 15 |
8.96 |
g/d |
1.27 |
4.92 |
unspecified method |
0.0 |
|
|
|
|
|
|
75980 |
1539 |
| BluHsd:LE |
food intake weight to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (2.5 ug/kg) (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
4.8 |
g/g |
0.2 |
0.57 |
unspecified method |
0.0 |
|
|
|
|
|
|
76185 |
1543 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
105.0 days
| 12 |
36.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75728 |
1538 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
8.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75739 |
1538 |
| BluHsd:LE |
food calorie intake level to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (25 ug/kg) (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
9.9 |
kcal/g |
0.4 |
1.13 |
unspecified method |
0.0 |
|
|
|
|
|
|
76208 |
1543 |
| F344/NHsd |
serum alkaline phosphatase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alkaline phosphatase amount |
male |
132.0 days-264.0 days |
9 |
98.8 |
U/l |
5.3 |
15.9 |
unspecified method |
0.0 |
|
|
|
|
|
|
84719 |
1599 |
| F344/NHsd |
serum total protein level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood total protein amount |
male |
579.0 days-945.0 days |
9 |
548.0 |
g/dl |
51.0 |
153.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
84729 |
1599 |
| F344/NHsd |
serum total protein level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood total protein amount |
male |
123.0 days-267.0 days |
8 |
579.0 |
g/dl |
14.0 |
39.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
84728 |
1599 |
| F344/NHsd |
serum total bilirubin level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood bilirubin amount |
male |
714.0 days-882.0 days |
5 |
9.35 |
mg/dl |
1.17 |
2.61 |
unspecified method |
0.0 |
|
|
|
|
|
|
84738 |
1599 |
| F344/NHsd |
serum creatinine level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood creatinine amount |
male |
132.0 days-264.0 days |
6 |
0.38 |
mg/dl |
0.0 |
0.01 |
unspecified method |
0.0 |
|
|
|
|
|
|
84739 |
1599 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
50.0 days-64.0 days |
6 |
34.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84836 |
1602 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64.0 days-78.0 days |
6 |
39.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84834 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64.0 days-78.0 days |
6 |
26.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84862 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57.0 days-71.0 days |
6 |
20.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84869 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64.0 days-78.0 days |
6 |
24.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84866 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70.0 days-84.0 days |
6 |
20.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84867 |
1602 |
| BN/Rj |
aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
female |
120.0 days-126.0 days |
6 |
1.2 |
null |
0.02 |
0.05 |
unspecified method |
0.0 |
|
|
|
|
elastin/collagen ratio |
|
96783 |
1680 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 17 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
80.28 |
ml/d |
3.62 |
10.24 |
unspecified method |
0.0 |
|
|
|
|
|
|
75893 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (1 mg/l) (for 31 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
127.22 |
ml/d |
15.17 |
42.91 |
unspecified method |
0.0 |
|
|
|
|
|
|
75900 |
1539 |
| W/Nin |
plasma retinol level |
controlled retinyl palmitate content diet (52 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
26.0 |
ug/dl |
2.0 |
4.9 |
unspecified method |
0.0 |
|
|
|
|
|
|
96743 |
1660 |
| W-LeprfaNin |
plasma retinol level |
controlled retinyl palmitate content diet (2.6 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
40.0 |
ug/dl |
1.6 |
3.92 |
unspecified method |
0.0 |
|
|
|
|
|
|
96745 |
1660 |
| Crl:SD |
ethanol drink intake rate |
controlled ethanol content drinking water (1 %) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
105.0 days
| 12 |
10.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75725 |
1538 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
105.0 days
| 12 |
33.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75727 |
1538 |
| CrljJcl:SD |
water drink intake rate |
gestation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 6 |
45.01 |
ml/d |
3.54 |
8.67 |
unspecified method |
0.0 |
|
|
|
|
|
|
75881 |
1539 |
| CrljJcl:SD |
food intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
140.0 days
| 15 |
12.53 |
g/d |
1.26 |
4.88 |
unspecified method |
0.0 |
|
|
|
|
|
|
75985 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
39.1 |
% |
1.47 |
5.88 |
unspecified method |
0.0 |
|
|
|
|
|
|
76025 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
39.6 |
% |
1.66 |
6.64 |
unspecified method |
0.0 |
|
|
|
|
|
|
76029 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
39.4 |
% |
2.22 |
8.88 |
unspecified method |
0.0 |
|
|
|
|
|
|
76033 |
1539 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64.0 days-78.0 days |
6 |
33.7 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84842 |
1602 |
| Crl:SD |
total calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
consumption behavior trait |
female |
42.0 days-105.0 days |
12 |
29.5 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
total energy intake |
|
76113 |
1538 |
| Crl:SD |
total calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
consumption behavior trait |
female |
42.0 days-105.0 days |
12 |
29.5 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
total energy intake |
|
76114 |
1538 |
| BluHsd:LE |
food intake weight to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (2.5 ug/kg) (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
7.1 |
g/g |
0.5 |
1.41 |
unspecified method |
0.0 |
|
|
|
|
|
|
76205 |
1543 |
| CrljJcl:SD |
food intake rate |
gestation (for 14 days) then controlled bisphenol A content drinking water (1 mg/l) (for 3 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
24.46 |
g/d |
2.64 |
7.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
75767 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 24 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
59.89 |
g/d |
5.63 |
15.92 |
unspecified method |
0.0 |
|
|
|
|
|
|
75805 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (1 mg/l) (for 31 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
53.67 |
g/d |
5.8 |
16.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
75811 |
1539 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70.0 days-84.0 days |
6 |
33.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84847 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64.0 days-78.0 days |
6 |
24.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84850 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50.0 days-64.0 days |
6 |
18.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84868 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70.0 days-84.0 days |
6 |
21.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84871 |
1602 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
4.24 |
g/d/100g |
0.06 |
0.18 |
unspecified method |
0.0 |
|
|
|
|
on days 95-98 |
|
85514 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
4.34 |
g/d/100g |
0.34 |
0.96 |
unspecified method |
0.0 |
|
|
|
|
on days 95-98 |
|
85517 |
1604 |
| F344/NHsd |
serum aspartate aminotransferase activity level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood aspartate transaminase amount |
male |
579.0 days-945.0 days |
6 |
120.8 |
U/l |
12.9 |
31.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
84717 |
1599 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57.0 days-71.0 days |
6 |
34.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84829 |
1602 |
| SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71.0 days-85.0 days |
6 |
6.1 |
x 1000 cells/ul |
0.56 |
1.38 |
unspecified method |
0.0 |
|
|
|
|
|
|
84901 |
1602 |
| SD |
blood differential white blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71.0 days-85.0 days |
6 |
8.81 |
x 1000 cells/ul |
1.05 |
2.56 |
unspecified method |
0.0 |
|
|
|
|
|
|
84904 |
1602 |
| SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85.0 days-99.0 days |
6 |
8.97 |
x 10E6 cells/ul |
0.2 |
0.49 |
unspecified method |
0.0 |
|
|
|
|
|
|
84914 |
1602 |
| SD |
hematocrit |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
45.25 |
% |
0.57 |
1.39 |
unspecified method |
0.0 |
|
|
|
|
|
|
84951 |
1602 |
| SD |
hematocrit |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
44.38 |
% |
0.79 |
1.94 |
unspecified method |
0.0 |
|
|
|
|
|
|
84952 |
1602 |
| SD |
hematocrit |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
40.22 |
% |
0.83 |
2.03 |
unspecified method |
0.0 |
|
|
|
|
|
|
84958 |
1602 |
| SD |
hematocrit |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
40.85 |
% |
0.51 |
1.24 |
unspecified method |
0.0 |
|
|
|
|
|
|
84959 |
1602 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (120 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
8.7 |
% |
0.4 |
1.06 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96878 |
1719 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (120 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
7.0 |
% |
0.3 |
0.67 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96886 |
1719 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (60 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
12.2 |
% |
0.5 |
1.73 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96891 |
1719 |
| HanTac:WH |
number of blastocysts/embryos lost postimplantation to litter size ratio |
bisphenol A (0.25 mg/kg/d) (for 14 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
embryonic growth trait |
female |
days
| 17 |
11.3 |
% |
5.46 |
22.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
96587 |
1559 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (120 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
8.0 |
% |
0.3 |
1.04 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96894 |
1719 |
| Hsd:WI |
serum superoxide dismutase activity level |
thymoquinone (15 mg/kg) (for 1 days) then fasting (for 16 hours) |
Aycan IO, et al., Int J Surg. 2014;12(3):213-8. doi: 10.1016/j.ijsu.2013.12.013. Epub 2014 Jan 2. |
blood superoxide dismutase amount |
not specified |
days
| 10 |
5.8 |
U/l |
0.13 |
0.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
85607 |
1618 |
| Crl:SD |
food intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
63.0 days-77.0 days |
8 |
24.0 |
g/d |
0.1 |
0.28 |
unspecified method |
0.0 |
|
|
|
|
CT |
|
75874 |
1540 |
| Crl:SD |
food intake rate |
control condition |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
42.0 days
| 8 |
18.0 |
g/d |
0.3 |
0.85 |
unspecified method |
0.0 |
|
|
|
|
C |
|
75876 |
1540 |
| CrljJcl:SD |
water drink intake rate |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 15 |
22.15 |
ml/d |
1.67 |
6.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
75989 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 15 |
30.45 |
ml/d |
1.42 |
5.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
75992 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 15 |
34.6 |
ml/d |
1.49 |
5.77 |
unspecified method |
0.0 |
|
|
|
|
|
|
75998 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 15 |
27.48 |
ml/d |
1.87 |
7.24 |
unspecified method |
0.0 |
|
|
|
|
|
|
76001 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
37.2 |
% |
2.79 |
11.16 |
unspecified method |
0.0 |
|
|
|
|
|
|
76037 |
1539 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64.0 days-78.0 days |
6 |
34.2 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84830 |
1602 |
| SD |
blood differential white blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71.0 days-85.0 days |
6 |
11.3 |
x 1000 cells/ul |
1.47 |
3.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
84887 |
1602 |
| SD |
blood hemoglobin level |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71.0 days-85.0 days |
6 |
11.57 |
g/dl |
0.38 |
0.92 |
unspecified method |
0.0 |
|
|
|
|
|
|
84946 |
1602 |
| SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71.0 days-85.0 days |
6 |
12.98 |
g/dl |
0.2 |
0.48 |
unspecified method |
0.0 |
|
|
|
|
|
|
84948 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71.0 days-85.0 days |
6 |
11.57 |
% |
0.14 |
0.34 |
unspecified method |
0.0 |
|
|
|
|
|
|
84963 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71.0 days-85.0 days |
6 |
12.35 |
% |
0.24 |
0.59 |
unspecified method |
0.0 |
|
|
|
|
|
|
84964 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
female |
71.0 days-85.0 days |
6 |
11.38 |
% |
0.37 |
0.9 |
unspecified method |
0.0 |
|
|
|
|
|
|
84970 |
1602 |
| SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71.0 days-85.0 days |
6 |
1095.83 |
x 1000 /ul |
79.61 |
195.01 |
unspecified method |
0.0 |
|
|
|
|
|
|
84975 |
1602 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
22.1 |
g/d |
0.71 |
2.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
85474 |
1604 |
| W/Nin |
food intake rate |
controlled retinyl palmitate content diet (26 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
17.4 |
g/d |
0.68 |
1.67 |
unspecified method |
0.0 |
|
|
|
|
|
|
96726 |
1660 |
| W-LeprfaNin |
food intake rate |
controlled retinyl palmitate content diet (52 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
28.1 |
g/d |
1.33 |
3.26 |
unspecified method |
0.0 |
|
|
|
|
|
|
96731 |
1660 |
| W/Nin |
plasma glucose level |
controlled retinyl palmitate content diet (52 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
105.48 |
mg/dl |
6.84 |
16.75 |
unspecified method |
0.0 |
|
|
|
|
|
|
96735 |
1660 |
| Y59/Zgd |
bone ash content |
naringenin (100 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.59 |
g |
0.02 |
0.05 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97415 |
1758 |
| Y59/Zgd |
bone ash content |
vitamin A (80 mg/kg/d) (for 14 days) and naringenin (100 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.75 |
g |
0.02 |
0.05 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97410 |
1758 |
| Y59/Zgd |
bone ash content |
vitamin A (80 mg/kg/d) (for 14 days) and quercetin (100 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.82 |
g |
0.02 |
0.06 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97408 |
1758 |
| SS-Renem1Mcwi+/- |
creatinine clearance to total kidney weight ratio |
controlled sodium content diet (0.4 %) (for 42 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
glomerular filtration trait |
female |
63.0 days
| 9 |
0.79 |
ml/min/g |
0.07 |
0.21 |
unspecified method |
0.0 |
|
|
|
|
|
|
98353 |
2038 |
| SHRSP/A3N |
ratio of deaths related to chronic hypertension to total study population during a period of time |
control condition |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
total life span |
male |
168.0 days-189.0 days |
25 |
0.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to chronic hypertension to total study population during a period of time (CMO:0003800) |
|
107517 |
3090 |
| WAG/Nov |
diastolic blood pressure |
control condition |
Shurligina AV, et al., Bull Exp Biol Med. 2013 Aug;155(4):421-4. doi: 10.1007/s10517-013-2167-4. |
arterial blood pressure trait |
male |
150.0 days-180.0 days |
10 |
82.0 |
mmHg |
7.4 |
23.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
107672 |
3096 |
| ISIAH |
systolic blood pressure |
control condition |
Shurligina AV, et al., Bull Exp Biol Med. 2013 Aug;155(4):421-4. doi: 10.1007/s10517-013-2167-4. |
arterial blood pressure trait |
male |
150.0 days-180.0 days |
10 |
179.0 |
mmHg |
12.7 |
40.16 |
unspecified method |
0.0 |
|
|
|
|
|
|
107671 |
3096 |
| SHRSP/A3N |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
control condition |
Willette RN, etal., J Cardiovasc Pharmacol. 2001 Oct;38(4):606-17. doi: 10.1097/00005344-200110000-00013. |
total life span |
male |
182.0 days-210.0 days |
20 |
0.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107933 |
3100 |
| SHRSP/A3N |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) |
Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. |
total life span |
male |
203.0 days-224.0 days |
20 |
55.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107113 |
3075 |
| SPRD.WKY-(D18Wox8-D18Rat44)/Ibmm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
99.0 days-120.0 days |
46 |
0.79 |
cm/week |
0.01 |
0.05 |
unspecified method |
0.0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11348 |
73 |
| SPRD.WKY-(D5Rat190-D5Rat114)(D18Rat102-D18Rat44)/Ibmm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) (for 133 days) |
Piessevaux G, et al., Mamm Genome. 2008 Dec 4 |
mammary gland integrity trait |
female |
days
| 36 |
0.37 |
cm/week |
0.03 |
0.18 |
unspecified method |
0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11349 |
74 |
| SS/HsdMcwiCrl |
food intake rate |
controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
eating behavior trait |
male |
112.0 days
| 9 |
21.4 |
g/d |
1.1 |
3.3 |
unspecified method |
0.0 |
|
|
|
|
|
|
67660 |
735 |
| SS/HsdMcwiCrl |
water drink intake rate |
controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
drinking behavior trait |
male |
112.0 days
| 5 |
30.1 |
ml/d |
0.8 |
1.79 |
unspecified method |
0.0 |
|
|
|
|
|
|
67666 |
735 |
| Crlj:WI |
plasma sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood sitosterol amount |
not specified |
77.0 days
| 2 |
2.4 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70533 |
1300 |
| GH |
plasma sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood sitosterol amount |
not specified |
77.0 days
| 4 |
2.62 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70536 |
1300 |
| SS/JrHsdMcwi |
urine potassium excretion rate |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine potassium amount |
female |
89.0 days-92.0 days |
17 |
1.02 |
mEq/d |
0.07 |
0.3 |
unspecified method |
0.0 |
|
|
|
urine potassium analysis |
umol/min |
|
69470 |
151 |
| SS/JrHsdMcwi |
plasma total protein level |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
blood total protein amount |
female |
89.0 days-92.0 days |
13 |
40.4 |
mg/ml |
3.1 |
11.18 |
unspecified method |
0.0 |
|
|
|
|
|
|
69484 |
151 |
| WKY/NCrlCrlj |
liver campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver campesterol amount |
not specified |
77.0 days
| 2 |
0.09 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70522 |
1300 |
| Crl:SD |
plasma phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood phytosterol amount |
not specified |
77.0 days
| 2 |
3.3 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70545 |
1300 |
| SHR/NCrl |
brain cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain cholesterol amount |
not specified |
77.0 days
| 2 |
11.76 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70527 |
1300 |
| Crl:SD |
liver phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver phytosterol amount |
not specified |
77.0 days
| 2 |
0.05 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70550 |
1300 |
| Crl:SD |
brain phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain phytosterol amount |
not specified |
77.0 days
| 2 |
0.03 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70554 |
1300 |
| SS/JrHsdMcwi |
plasma creatinine level |
controlled sodium content diet (4 %) (for 21 days) |
Mattson DL, et al., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30. |
blood creatinine amount |
not specified |
84.0 days
| |
0.34 |
mg/dl |
0.04 |
|
unspecified method |
0.0 |
|
|
|
|
|
|
69286 |
1057 |
| SS-Rag1em2Mcwi |
urine albumin excretion rate |
controlled sodium content diet (4 %) (for 21 days) |
Mattson DL, et al., Am J Physiol Regul Integr Comp Physiol. 2013 Jan 30. |
urine albumin amount |
not specified |
84.0 days
| 4 |
19.0 |
mg/d |
3.0 |
6.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
69293 |
1057 |
| SS/JrHsdMcwi |
urine sodium excretion rate |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
89.0 days-92.0 days |
17 |
5.06 |
mEq/d |
0.6 |
2.49 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
umol/min |
|
69460 |
151 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (500 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
24.5 |
g/d |
0.32 |
0.9 |
unspecified method |
0.0 |
|
|
|
|
|
|
85478 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
17.9 |
g/d |
1.77 |
5.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
85480 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
3.96 |
g/d/100g |
0.35 |
0.98 |
unspecified method |
0.0 |
|
|
|
|
on days 95-98 |
|
85516 |
1604 |
| BluHsd:LE |
total food calorie intake rate |
controlled in utero environment (for 9 days) and bisphenol A (25 ug/kg) (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
2955.2 |
kcal/d |
65.0 |
183.85 |
unspecified method |
0.0 |
|
|
|
|
|
|
76184 |
1543 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (500 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
24.7 |
g/d |
0.46 |
1.3 |
unspecified method |
0.0 |
|
|
|
|
|
|
85460 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
18.8 |
g/d |
0.92 |
2.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
85463 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (300 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
23.4 |
g/d |
0.42 |
1.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
85483 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
18.3 |
g/d |
1.98 |
5.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
85486 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
5.74 |
g/d/100g |
0.1 |
0.29 |
unspecified method |
0.0 |
|
|
|
|
on days 11-14 |
|
85489 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
4.53 |
g/d/100g |
0.13 |
0.36 |
unspecified method |
0.0 |
|
|
|
|
on days 53-56 |
|
85502 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (500 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
4.49 |
g/d/100g |
0.08 |
0.23 |
unspecified method |
0.0 |
|
|
|
|
on days 74-77 |
|
85508 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 98 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 8 |
4.05 |
g/d/100g |
0.08 |
0.24 |
unspecified method |
0.0 |
|
|
|
|
on days 95-98 |
|
85513 |
1604 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (20 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
22.7 |
% |
0.4 |
1.06 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96873 |
1719 |
| Crl:SD |
metformin drink intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
63.0 days-77.0 days |
8 |
37.0 |
ml/d |
0.5 |
1.41 |
unspecified method |
0.0 |
|
|
|
|
metformin drink intake rate |
|
75866 |
1540 |
| CrljJcl:SD |
water drink intake rate |
gestation (for 21 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 6 |
77.08 |
ml/d |
4.24 |
10.39 |
unspecified method |
0.0 |
|
|
|
|
|
|
75883 |
1539 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
105.0 days
| 12 |
8.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75734 |
1538 |
| BluHsd:LE |
total food calorie intake rate |
vehicle control condition (for 30 days) and controlled in utero environment (for 9 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
2103.7 |
kcal/d |
62.9 |
177.91 |
unspecified method |
0.0 |
|
|
|
|
|
|
76169 |
1543 |
| BluHsd:LE |
food calorie intake level to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (25 ug/kg) (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
12.1 |
kcal/g |
2.1 |
5.94 |
unspecified method |
0.0 |
|
|
|
|
|
|
76186 |
1543 |
| BluHsd:LE |
total food calorie intake rate |
controlled in utero environment (for 9 days) and bisphenol A (2.5 ug/kg) (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
2990.7 |
kcal/d |
136.6 |
386.36 |
unspecified method |
0.0 |
|
|
|
|
|
|
76183 |
1543 |
| BluHsd:LE |
food calorie intake level to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (2.5 ug/kg) (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
9.8 |
kcal/g |
0.3 |
0.85 |
unspecified method |
0.0 |
|
|
|
|
|
|
76206 |
1543 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
8.7 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75738 |
1538 |
| BluHsd:LE |
food intake weight to change in body weight ratio |
controlled in utero environment (for 9 days) and vehicle control condition (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
6.7 |
g/g |
0.3 |
0.85 |
unspecified method |
0.0 |
|
|
|
|
|
|
76203 |
1543 |
| F344/NHsd |
serum gamma-glutamyltransferase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood gamma-glutamyltransferase amount |
male |
123.0 days-267.0 days |
8 |
1.6 |
U/l |
1.0 |
2.83 |
unspecified method |
0.0 |
|
|
|
|
|
|
84724 |
1599 |
| F344/NHsd |
serum albumin level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood albumin amount |
male |
123.0 days-267.0 days |
8 |
126.0 |
g/dl |
4.0 |
11.31 |
unspecified method |
0.0 |
|
|
|
|
|
|
84732 |
1599 |
| F344/NHsd |
serum total bilirubin level |
fasting (for 16 hours) then sodium chloride solution (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood bilirubin amount |
male |
579.0 days-945.0 days |
9 |
14.62 |
mg/dl |
1.17 |
3.51 |
unspecified method |
0.0 |
|
|
|
|
|
|
84737 |
1599 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57.0 days-71.0 days |
6 |
36.7 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84833 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70.0 days-84.0 days |
6 |
31.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84839 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50.0 days-64.0 days |
6 |
18.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84864 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57.0 days-71.0 days |
6 |
25.2 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84861 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
64.0 days-78.0 days |
6 |
24.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84870 |
1602 |
| SD |
red blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
8.47 |
x 10E6 cells/ul |
0.19 |
0.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
84896 |
1602 |
| BN/Rj |
aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
male |
120.0 days-126.0 days |
6 |
1.14 |
null |
0.02 |
0.06 |
unspecified method |
0.0 |
|
|
|
|
elastin/collagen ratio |
|
96782 |
1680 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 24 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
95.55 |
ml/d |
7.11 |
20.11 |
unspecified method |
0.0 |
|
|
|
|
|
|
75894 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 14 days) then controlled bisphenol A content drinking water (1 mg/l) (for 3 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
46.45 |
ml/d |
2.57 |
7.27 |
unspecified method |
0.0 |
|
|
|
|
|
|
75896 |
1539 |
| Crl:SD |
food intake rate |
controlled ethanol content drinking water (1 %) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
105.0 days
| 12 |
10.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75733 |
1538 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
30.1 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75732 |
1538 |
| Crl:SD |
food intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
105.0 days
| 12 |
8.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75743 |
1538 |
| Crl:SD |
bisphenol A in fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 7 days) and controlled bisphenol A content drinking water (2.5 mg/l) (for 7 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days
| 12 |
19.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75744 |
1538 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
140.0 days
| 15 |
81.29 |
ml/d |
4.06 |
15.72 |
unspecified method |
0.0 |
|
|
|
|
|
|
76006 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 15 |
27.36 |
ml/d |
1.22 |
4.73 |
unspecified method |
0.0 |
|
|
|
|
|
|
76007 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
24.2 |
% |
1.0 |
4.0 |
unspecified method |
0.0 |
|
|
|
|
|
|
76024 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
26.5 |
% |
2.11 |
8.44 |
unspecified method |
0.0 |
|
|
|
|
|
|
76028 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
47.0 |
% |
1.99 |
7.96 |
unspecified method |
0.0 |
|
|
|
|
|
|
76030 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
47.1 |
% |
2.01 |
8.04 |
unspecified method |
0.0 |
|
|
|
|
|
|
76034 |
1539 |
| Crl:SD |
fructose drink calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.25 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
6.0 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
fructose energy intake |
|
76103 |
1538 |
| Crl:SD |
food calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
24.6 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
food energy intake |
|
76106 |
1538 |
| Crl:SD |
food calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
24.1 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
food energy intake |
|
76107 |
1538 |
| Crl:SD |
total calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
consumption behavior trait |
female |
42.0 days-105.0 days |
12 |
29.7 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
total energy intake |
|
76112 |
1538 |
| HanTac:WH |
number of blastocysts/embryos lost postimplantation to litter size ratio |
vehicle control condition (for 14 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
embryonic growth trait |
female |
days
| 18 |
7.9 |
% |
2.71 |
11.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
96588 |
1559 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 17 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
42.77 |
g/d |
2.47 |
6.99 |
unspecified method |
0.0 |
|
|
|
|
|
|
75804 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
54.66 |
g/d |
4.72 |
13.35 |
unspecified method |
0.0 |
|
|
|
|
|
|
75806 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (1 mg/l) (for 17 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
43.39 |
g/d |
3.56 |
10.07 |
unspecified method |
0.0 |
|
|
|
|
|
|
75808 |
1539 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57.0 days-71.0 days |
6 |
34.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84845 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50.0 days-64.0 days |
6 |
22.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84848 |
1602 |
| Crl:CD(SD) |
food intake rate |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 19 |
24.8 |
g/d |
0.53 |
2.3 |
unspecified method |
0.0 |
|
|
|
|
|
|
85294 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 19 |
4.07 |
g/d/100g |
0.05 |
0.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
85308 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 19 |
23.9 |
g/d |
0.39 |
1.7 |
unspecified method |
0.0 |
|
|
|
|
|
|
85296 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
168.0 days
| 19 |
4.01 |
g/d/100g |
0.27 |
1.17 |
unspecified method |
0.0 |
|
|
|
|
|
|
85309 |
1604 |
| Crl:CD(SD) |
liver wet weight |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver mass |
male |
170.0 days
| 19 |
17.65 |
g |
0.54 |
2.35 |
unspecified method |
0.0 |
|
|
|
|
liver weight not available |
|
85402 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (300 mg/kg) (for 77 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 8 |
24.3 |
g/d |
0.32 |
0.9 |
unspecified method |
0.0 |
|
|
|
|
|
|
85477 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (300 mg/kg) (for 14 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 8 |
6.04 |
g/d/100g |
0.21 |
0.58 |
unspecified method |
0.0 |
|
|
|
|
on days 11-14 |
|
85492 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
4.9 |
g/d/100g |
0.18 |
0.5 |
unspecified method |
0.0 |
|
|
|
|
on days 32-35 |
|
85499 |
1604 |
| F344/NHsd |
serum aspartate aminotransferase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood aspartate transaminase amount |
male |
123.0 days-267.0 days |
7 |
349.6 |
U/l |
34.3 |
90.75 |
unspecified method |
0.0 |
|
|
|
|
|
|
84716 |
1599 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64.0 days-78.0 days |
6 |
35.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84826 |
1602 |
| SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85.0 days-99.0 days |
6 |
8.64 |
x 10E6 cells/ul |
0.24 |
0.6 |
unspecified method |
0.0 |
|
|
|
|
|
|
84899 |
1602 |
| SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85.0 days-99.0 days |
6 |
8.8 |
x 10E6 cells/ul |
0.13 |
0.31 |
unspecified method |
0.0 |
|
|
|
|
|
|
84898 |
1602 |
| SD |
red blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
8.97 |
x 10E6 cells/ul |
0.2 |
0.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
84912 |
1602 |
| HanTac:WH |
number of blastocysts/embryos lost postimplantation to litter size ratio |
bisphenol A (5 mg/kg/d) (for 14 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
embryonic growth trait |
female |
days
| 18 |
5.9 |
% |
1.15 |
4.9 |
unspecified method |
0.0 |
|
|
|
|
|
|
96590 |
1559 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (20 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
20.5 |
% |
0.8 |
1.79 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96881 |
1719 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (160 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
6.3 |
% |
0.3 |
0.67 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96888 |
1719 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (80 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
9.0 |
% |
0.2 |
0.45 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96884 |
1719 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (20 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
21.0 |
% |
0.4 |
1.39 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96889 |
1719 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 31 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
50.69 |
g/d |
5.75 |
16.26 |
unspecified method |
0.0 |
|
|
|
|
|
|
75801 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 24 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
55.5 |
g/d |
5.77 |
16.32 |
unspecified method |
0.0 |
|
|
|
|
|
|
75770 |
1539 |
| Crl:SD |
food intake rate |
controlled fructose content diet (66 %) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
42.0 days
| 9 |
19.0 |
g/d |
0.3 |
0.9 |
unspecified method |
0.0 |
|
|
|
|
F |
|
75875 |
1540 |
| CrljJcl:SD |
water drink intake rate |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 15 |
32.67 |
ml/d |
2.67 |
10.34 |
unspecified method |
0.0 |
|
|
|
|
|
|
75986 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
140.0 days
| 15 |
19.55 |
ml/d |
1.4 |
5.42 |
unspecified method |
0.0 |
|
|
|
|
|
|
75991 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
70.0 days
| 15 |
24.02 |
ml/d |
1.41 |
5.46 |
unspecified method |
0.0 |
|
|
|
|
|
|
75993 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
140.0 days
| 15 |
22.6 |
ml/d |
1.36 |
5.27 |
unspecified method |
0.0 |
|
|
|
|
|
|
75997 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 15 |
42.57 |
ml/d |
3.84 |
14.87 |
unspecified method |
0.0 |
|
|
|
|
|
|
76004 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
70.0 days
| 15 |
83.54 |
ml/d |
4.75 |
18.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
76005 |
1539 |
| SD |
blood differential white blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71.0 days-85.0 days |
6 |
7.68 |
x 1000 cells/ul |
1.1 |
2.69 |
unspecified method |
0.0 |
|
|
|
|
|
|
84888 |
1602 |
| SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
male |
71.0 days-85.0 days |
6 |
7.58 |
x 1000 cells/ul |
0.55 |
1.34 |
unspecified method |
0.0 |
|
|
|
|
|
|
84890 |
1602 |
| SD |
blood hemoglobin level |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
male |
85.0 days-99.0 days |
6 |
13.75 |
g/dl |
0.26 |
0.64 |
unspecified method |
0.0 |
|
|
|
|
|
|
84944 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71.0 days-85.0 days |
6 |
11.97 |
% |
0.09 |
0.23 |
unspecified method |
0.0 |
|
|
|
|
|
|
84965 |
1602 |
| SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
85.0 days-99.0 days |
6 |
1122.17 |
x 1000 /ul |
129.6 |
317.45 |
unspecified method |
0.0 |
|
|
|
|
|
|
84980 |
1602 |
| SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
male |
71.0 days-85.0 days |
6 |
1263.0 |
x 1000 /ul |
34.55 |
84.62 |
unspecified method |
0.0 |
|
|
|
|
|
|
84978 |
1602 |
| SD |
platelet count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
71.0 days-85.0 days |
6 |
816.0 |
x 1000 /ul |
44.32 |
108.56 |
unspecified method |
0.0 |
|
|
|
|
|
|
84981 |
1602 |
| SD |
platelet count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
platelet quantity |
female |
85.0 days-99.0 days |
6 |
931.0 |
x 1000 /ul |
34.34 |
84.12 |
unspecified method |
0.0 |
|
|
|
|
|
|
84986 |
1602 |
| Crl:CD(SD) |
food intake rate |
standard diet then acetaminophen (500 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
24.9 |
g/d |
0.85 |
2.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
85472 |
1604 |
| CrljJcl:SD |
food intake rate |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
male |
42.0 days
| 15 |
14.48 |
g/d |
2.16 |
8.37 |
unspecified method |
0.0 |
|
|
|
|
|
|
75933 |
1539 |
| CrljJcl:SD |
food intake rate |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
male |
70.0 days
| 15 |
22.07 |
g/d |
3.86 |
14.95 |
unspecified method |
0.0 |
|
|
|
|
|
|
75934 |
1539 |
| W/Nin |
plasma glucose level |
controlled retinyl palmitate content diet (2.6 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
99.54 |
mg/dl |
3.6 |
8.82 |
unspecified method |
0.0 |
|
|
|
|
|
|
96733 |
1660 |
| W/Nin |
plasma glucose level |
controlled retinyl palmitate content diet (129 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
96.66 |
mg/dl |
5.94 |
14.55 |
unspecified method |
0.0 |
|
|
|
|
|
|
96736 |
1660 |
| W-LeprfaNin |
plasma glucose level |
controlled retinyl palmitate content diet (26 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
112.68 |
mg/dl |
7.2 |
17.64 |
unspecified method |
0.0 |
|
|
|
|
|
|
96738 |
1660 |
| W-LeprfaNin |
plasma glucose level |
controlled retinyl palmitate content diet (2.6 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
126.36 |
mg/dl |
9.36 |
22.93 |
unspecified method |
0.0 |
|
|
|
|
|
|
96737 |
1660 |
| Y59/Zgd |
bone ash content |
ethanol (0.5 %) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.62 |
g |
0.01 |
0.02 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97397 |
1758 |
| Y59/Zgd |
bone ash content |
vitamin A (80 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.64 |
g |
0.01 |
0.04 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97402 |
1758 |
| Y59/Zgd |
bone ash content |
chrysin (100 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.59 |
g |
0.0 |
0.01 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97414 |
1758 |
| SS-Renem1Mcwi+/+ |
creatinine clearance to total kidney weight ratio |
controlled sodium content diet (0.4 %) (for 42 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
glomerular filtration trait |
male |
63.0 days
| 5 |
0.9 |
ml/min/g |
0.1 |
0.22 |
unspecified method |
0.0 |
|
|
|
|
|
|
98349 |
2038 |
| F344 |
mean arterial blood pressure |
sucrose (10 %) (for 0.5 hours) |
Westlund KN, et al., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3. |
arterial blood pressure trait |
male |
days
| 2 |
123.56 |
mmHg |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
105570 |
3018 |
| F344 |
mean arterial blood pressure |
4-methyl-2-(piperidin-1-yl)-quinoline (1 mg/kg) (for 0.5 hours) |
Westlund KN, et al., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3. |
arterial blood pressure trait |
male |
days
| 3 |
120.97 |
mmHg |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
105571 |
3018 |
| SHRSP/A3N |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 112 days) and controlled fat content diet (24.5 %) (for 112 days) |
Willette RN, etal., J Cardiovasc Pharmacol. 2001 Oct;38(4):606-17. doi: 10.1097/00005344-200110000-00013. |
total life span |
male |
182.0 days-210.0 days |
20 |
65.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107934 |
3100 |
| SHRSP/A3N |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 112 days) and controlled fat content diet (24.5 %) (for 112 days) and controlled enrasentan content diet (2400 ppm) (for 112 days) |
Willette RN, etal., J Cardiovasc Pharmacol. 2001 Oct;38(4):606-17. doi: 10.1097/00005344-200110000-00013. |
total life span |
male |
182.0 days-210.0 days |
20 |
10.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107936 |
3100 |
| SHRSP/A3N |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 126 days) and controlled fat content diet (24.5 %) (for 126 days) and controlled carvedilol content diet (2400 ppm) (for 126 days) |
Barone FC, etal., Pharmacology. 2007;80(2-3):166-76. doi: 10.1159/000103384. Epub 2007 Jun 4. |
total life span |
male |
203.0 days-224.0 days |
20 |
0.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107112 |
3075 |
| SPRD.WKY-(D5Rat190-D5Rat114)/Ibmm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) |
Stieber D, et al., Int J Cancer. 2007 Jan 17 |
mammary gland integrity trait |
female |
107.0 days-128.0 days |
14 |
0.62 |
cm/week |
0.02 |
0.08 |
unspecified method |
0.0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11347 |
73 |
| WF.WKY-(D5Wox7-D5Uwm37)/Uwm |
mammary tumor number |
7,12-dimethyltetraphene (65 mg/kg) |
Samuelson DJ, et al., Carcinogenesis 2003 Sep;24(9):1455-60 |
mammary gland integrity trait |
female |
155.0 days-160.0 days |
13 |
1.1 |
null |
0.3 |
1.08 |
unspecified method |
|
|
|
|
|
3X3 mm diameter or larger |
|
11744 |
142 |
| WF/NHsd |
mammary tumor number |
7,12-dimethyltetraphene (65 mg/kg) |
Samuelson DJ, et al., Carcinogenesis 2003 Sep;24(9):1455-60 |
mammary gland integrity trait |
female |
155.0 days-160.0 days |
50 |
6.9 |
null |
0.4 |
2.83 |
unspecified method |
|
|
|
|
|
3X3 mm diameter or larger |
|
11743 |
142 |
| WF.WKY-(D5Rat26-D5Uwm42)/Uwm |
mammary tumor number |
7,12-dimethyltetraphene (65 mg/kg) |
Samuelson DJ, et al., Carcinogenesis 2003 Sep;24(9):1455-60 |
mammary gland integrity trait |
female |
155.0 days-160.0 days |
29 |
5.7 |
null |
0.6 |
3.23 |
unspecified method |
|
|
|
|
|
3X3 mm diameter or larger |
|
11745 |
142 |
| SPRD.WKY-(D10Rat91-D10Rat135)/Ibmm |
mammary tumor growth rate |
7,12-dimethyltetraphene (65 mg/kg) (for 133 days) |
Piessevaux G, et al., Mamm Genome. 2008 Dec 4 |
mammary gland integrity trait |
female |
days
| 33 |
0.53 |
cm/week |
0.02 |
0.11 |
unspecified method |
0 |
DMBA oral gavage |
|
|
|
the first 3 weeks of tumor growth |
|
11512 |
74 |
| SS/HsdMcwiCrl |
food intake rate |
controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
eating behavior trait |
male |
112.0 days
| 8 |
25.2 |
g/d |
1.3 |
3.68 |
unspecified method |
0.0 |
|
|
|
|
|
|
67659 |
735 |
| SS/HsdMcwiCrl |
tibia length |
controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) |
Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. |
tibia length |
male |
112.0 days
| 6 |
4.3 |
cm |
0.03 |
0.07 |
unspecified method |
0.0 |
|
|
|
|
|
|
67612 |
735 |
| Crl:SD |
brain campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain campesterol amount |
not specified |
77.0 days
| 2 |
0.02 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70528 |
1300 |
| WKY/NCrlCrlj |
brain campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain campesterol amount |
not specified |
77.0 days
| 2 |
0.02 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70530 |
1300 |
| SS/JrHsdMcwi |
urine potassium level |
controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine potassium amount |
female |
92.0 days-94.0 days |
14 |
124.4 |
mmol/l |
8.8 |
32.93 |
unspecified method |
0.0 |
|
|
|
urine potassium analysis |
|
|
69472 |
151 |
| Crlj:WI |
liver sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver sitosterol amount |
not specified |
77.0 days
| 2 |
0.04 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70538 |
1300 |
| Crlj:WI |
brain sitosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain sitosterol amount |
not specified |
77.0 days
| 2 |
0.04 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70542 |
1300 |
| Crlj:WI |
plasma campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood campesterol amount |
not specified |
77.0 days
| 2 |
1.9 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
plasma campesterol measurement test |
|
|
70516 |
1300 |
| Crl:SD |
liver campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver campesterol amount |
not specified |
77.0 days
| 2 |
0.03 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70520 |
1300 |
| Crlj:WI |
liver campesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver campesterol amount |
not specified |
77.0 days
| 2 |
0.04 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue campesterol measurement test |
|
|
70521 |
1300 |
| WKY/NCrlCrlj |
brain cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
brain cholesterol amount |
not specified |
77.0 days
| 2 |
12.15 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue lipid analysis |
|
|
70526 |
1300 |
| Crlj:WI |
plasma phytosterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
blood phytosterol amount |
not specified |
77.0 days
| 2 |
4.3 |
mg/dl |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
70546 |
1300 |
| BN/NHsdMcwi |
urine sodium excretion rate |
controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) |
Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. |
urine sodium amount |
female |
89.0 days-92.0 days |
24 |
6.35 |
mEq/d |
0.35 |
1.74 |
unspecified method |
0.0 |
|
|
|
urine sodium analysis |
umol/min |
|
69459 |
151 |
| WKY/NCrlCrlj |
liver cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver cholesterol amount |
not specified |
77.0 days
| 2 |
2.1 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue total cholesterol analysis |
|
|
70165 |
1300 |
| SHR/NCrl |
liver cholesterol level |
control condition |
Yu H, et al., BMC Cardiovasc Disord 2003 Jun 3;3(1):4. |
liver cholesterol amount |
not specified |
77.0 days
| 2 |
1.85 |
mg/g |
|
|
unspecified method |
0.0 |
|
|
|
tissue total cholesterol analysis |
|
|
70166 |
1300 |
| Crl:CD(SD) |
liver wet weight |
standard diet then acetaminophen (500 mg/kg) (for 99 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
liver mass |
male |
170.0 days
| 8 |
20.3 |
g |
0.7 |
1.98 |
unspecified method |
0.0 |
|
|
|
|
liver weight not available |
|
85556 |
1604 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 6 |
43.84 |
g/d |
3.26 |
7.99 |
unspecified method |
0.0 |
|
|
|
|
|
|
75764 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 21 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 6 |
52.68 |
g/d |
6.85 |
16.78 |
unspecified method |
0.0 |
|
|
|
|
|
|
75766 |
1539 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 19 |
20.1 |
g/d |
0.5 |
2.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
85295 |
1604 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
147.0 days
| 19 |
19.4 |
g/d |
0.87 |
3.8 |
unspecified method |
0.0 |
|
|
|
|
|
|
85297 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 19 |
4.74 |
g/d/100g |
0.11 |
0.5 |
unspecified method |
0.0 |
|
|
|
|
|
|
85304 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet then acetaminophen (300 mg/kg) (for 35 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
105.0 days
| 8 |
5.2 |
g/d/100g |
0.07 |
0.21 |
unspecified method |
0.0 |
|
|
|
|
on days 32-35 |
|
85495 |
1604 |
| Crl:CD(SD) |
food intake weight to body weight ratio |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
4.23 |
g/d/100g |
0.27 |
0.77 |
unspecified method |
0.0 |
|
|
|
|
on days 53-56 |
|
85505 |
1604 |
| SS-Chr 12BN/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (60 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
7 |
13.8 |
% |
0.8 |
2.12 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96875 |
1719 |
| Crl:SD |
water drink intake rate |
control condition |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
63.0 days-77.0 days |
8 |
43.0 |
ml/d |
1.7 |
4.81 |
unspecified method |
0.0 |
|
|
|
|
C |
|
75864 |
1540 |
| Crl:SD |
metformin drink intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) then controlled fructose content diet (66 %) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
drinking behavior trait |
male |
42.0 days
| 10 |
33.0 |
ml/d |
0.6 |
1.9 |
unspecified method |
0.0 |
|
|
|
|
metformin drink intake rate |
|
75869 |
1540 |
| BN/Rj |
aorta wall extracellular elastin dry weight to aorta wall dry weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
male |
120.0 days-126.0 days |
6 |
31.4 |
% |
0.49 |
1.2 |
unspecified method |
0.0 |
|
|
|
|
thoracic aortic elastin to aortic dry weight ratio ruptures |
|
96778 |
1680 |
| CrljJcl:SD |
water drink intake rate |
gestation (for 21 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 6 |
97.33 |
ml/d |
10.65 |
26.09 |
unspecified method |
0.0 |
|
|
|
|
|
|
75884 |
1539 |
| Crl:SD |
fructose drink intake rate |
controlled fructose content drinking water (5 %) (for 70 days) and controlled ethanol content drinking water (1 %) (for 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
105.0 days
| 12 |
32.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75726 |
1538 |
| BluHsd:LE |
total food calorie intake rate |
controlled in utero environment (for 9 days) and vehicle control condition (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
2995.2 |
kcal/d |
187.0 |
528.92 |
unspecified method |
0.0 |
|
|
|
|
|
|
76182 |
1543 |
| CrljJcl:SD |
food intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
male |
140.0 days
| 15 |
27.97 |
g/d |
3.2 |
12.39 |
unspecified method |
0.0 |
|
|
|
|
|
|
75982 |
1539 |
| BluHsd:LE |
food calorie intake level to change in body weight ratio |
controlled in utero environment (for 9 days) and vehicle control condition (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
10.1 |
kcal/g |
0.3 |
0.85 |
unspecified method |
0.0 |
|
|
|
|
|
|
76204 |
1543 |
| CrljJcl:SD |
water drink intake rate |
gestation (for 21 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 6 |
128.6 |
ml/d |
13.29 |
32.55 |
unspecified method |
0.0 |
|
|
|
|
|
|
75885 |
1539 |
| BluHsd:LE |
food intake weight to change in body weight ratio |
controlled in utero environment (for 9 days) and vehicle control condition (for 30 days) then maternal milk (for 21 days) then controlled fat content diet (21.2 %) (for 28 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
4.7 |
g/g |
0.2 |
0.57 |
unspecified method |
0.0 |
|
|
|
|
|
|
76197 |
1543 |
| Crl:SD |
fructose drink intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
28.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
week one |
|
75730 |
1538 |
| F344/NHsd |
serum alkaline phosphatase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alkaline phosphatase amount |
male |
714.0 days-882.0 days |
5 |
48.2 |
U/l |
5.8 |
12.97 |
unspecified method |
0.0 |
|
|
|
|
|
|
84722 |
1599 |
| F344/NHsd |
serum albumin level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood albumin amount |
male |
714.0 days-882.0 days |
5 |
108.0 |
g/dl |
9.0 |
20.12 |
unspecified method |
0.0 |
|
|
|
|
|
|
84734 |
1599 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 22 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
64.0 days-78.0 days |
6 |
34.8 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84838 |
1602 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50.0 days-64.0 days |
6 |
21.3 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84852 |
1602 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70.0 days-84.0 days |
6 |
23.1 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84851 |
1602 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 15 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
57.0 days-71.0 days |
6 |
23.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84853 |
1602 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 8 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
50.0 days-64.0 days |
6 |
19.9 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84856 |
1602 |
| LOU/MBbb |
aorta wall extracellular elastin dry weight to aorta wall dry weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
male |
120.0 days-126.0 days |
6 |
37.2 |
% |
0.41 |
1.0 |
unspecified method |
0.0 |
|
|
|
|
thoracic aortic elastin to aortic dry weight ratio |
|
96780 |
1680 |
| LOU/MBbb |
aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio |
control condition |
Kota L, et al., Physiol Genomics. 2007 Jun 19;30(1):17-25. Epub 2007 Mar 13. |
thoracic aorta molecular composition trait |
female |
120.0 days-126.0 days |
6 |
1.58 |
null |
0.04 |
0.09 |
unspecified method |
0.0 |
|
|
|
|
elastin/collagen ratio |
|
96785 |
1680 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 20 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 9 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
56.77 |
ml/d |
4.38 |
12.39 |
unspecified method |
0.0 |
|
|
|
|
|
|
75887 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 17 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
73.26 |
ml/d |
6.32 |
17.88 |
unspecified method |
0.0 |
|
|
|
|
|
|
75888 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 20 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 9 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
60.47 |
ml/d |
5.3 |
14.99 |
unspecified method |
0.0 |
|
|
|
|
|
|
75892 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 31 days) then lactation (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
130.25 |
ml/d |
21.07 |
59.59 |
unspecified method |
0.0 |
|
|
|
|
|
|
75890 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 20 days) then controlled bisphenol A content drinking water (1 mg/l) (for 9 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
60.73 |
ml/d |
4.76 |
13.46 |
unspecified method |
0.0 |
|
|
|
|
|
|
75897 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (1 mg/l) (for 17 days) then lactation (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
79.88 |
ml/d |
3.13 |
8.85 |
unspecified method |
0.0 |
|
|
|
|
|
|
75898 |
1539 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 21 days) then controlled bisphenol A content drinking water (1 mg/l) (for 24 days) then lactation (for 14 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
104.63 |
ml/d |
8.29 |
23.45 |
unspecified method |
0.0 |
|
|
|
|
|
|
75899 |
1539 |
| W/Nin |
plasma retinol level |
controlled retinyl palmitate content diet (129 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
29.0 |
ug/dl |
3.4 |
8.33 |
unspecified method |
0.0 |
|
|
|
|
|
|
96744 |
1660 |
| W-LeprfaNin |
plasma retinol level |
controlled retinyl palmitate content diet (52 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood vitamin A amount |
male |
284.0 days
| 6 |
46.0 |
ug/dl |
3.9 |
9.55 |
unspecified method |
0.0 |
|
|
|
|
|
|
96747 |
1660 |
| CrljJcl:SD |
food intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
male |
42.0 days
| 15 |
14.14 |
g/d |
1.93 |
7.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
75983 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
140.0 days
| 15 |
93.29 |
% |
5.87 |
22.73 |
unspecified method |
0.0 |
|
|
|
|
|
|
76018 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
70.0 days
| 15 |
77.67 |
% |
2.53 |
9.8 |
unspecified method |
0.0 |
|
|
|
|
|
|
76017 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 119 days) and water (for 119 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
140.0 days
| 15 |
66.47 |
% |
2.54 |
9.84 |
unspecified method |
0.0 |
|
|
|
|
|
|
76021 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
62.7 |
% |
2.55 |
10.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
76023 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
59.4 |
% |
3.63 |
14.52 |
unspecified method |
0.0 |
|
|
|
|
|
|
76031 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.5 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 16 |
26.7 |
% |
1.85 |
7.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
76036 |
1539 |
| CrljJcl:SD |
saccharin intake volume to total fluid intake volume ratio |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled saccharin content drinking water (0.25 %) (for 7 days) and water (for 7 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 16 |
58.9 |
% |
2.96 |
11.84 |
unspecified method |
0.0 |
|
|
|
|
|
|
76035 |
1539 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57.0 days-71.0 days |
6 |
34.5 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84841 |
1602 |
| Crl:SD |
fructose drink calorie intake rate |
controlled ethanol content drinking water (1 %) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
0.0 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
76100 |
1538 |
| Crl:SD |
fructose drink calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (0.025 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
5.6 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
fructose energy intake |
|
76102 |
1538 |
| Crl:SD |
fructose drink calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
drinking behavior trait |
female |
42.0 days-105.0 days |
12 |
4.9 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
fructose energy intake |
|
76104 |
1538 |
| Crl:SD |
food calorie intake rate |
controlled fructose content drinking water (5 %) (between 7 and 70 days) and controlled bisphenol A content drinking water (2.5 mg/l) (between 7 and 70 days) |
Ronn M, et al., Toxicology. 2013 Jan 7;303:125-32. doi: 10.1016/j.tox.2012.09.013. Epub 2012 Nov 8. |
eating behavior trait |
female |
42.0 days-105.0 days |
12 |
24.6 |
kcal/d |
|
|
unspecified method |
0.0 |
|
|
|
|
food energy intake |
|
76109 |
1538 |
| BluHsd:LE |
food intake weight to change in body weight ratio |
controlled in utero environment (for 9 days) and bisphenol A (25 ug/kg) (for 30 days) then maternal milk (for 21 days) |
Nanjappa MK, et al., Toxicol Lett. 2014 Mar 21;225(3):479-87. doi: 10.1016/j.toxlet.2014.01.024. Epub 2014 Jan 26. |
eating behavior trait |
male |
71.0 days-98.0 days |
8 |
6.9 |
g/g |
0.5 |
1.41 |
unspecified method |
0.0 |
|
|
|
|
|
|
76207 |
1543 |
| CrljJcl:SD |
food intake rate |
gestation (for 20 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 9 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
22.61 |
g/d |
1.84 |
5.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
75803 |
1539 |
| CrljJcl:SD |
food intake rate |
gestation (for 14 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 3 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
days
| 8 |
26.94 |
g/d |
1.89 |
5.35 |
unspecified method |
0.0 |
|
|
|
|
|
|
75809 |
1539 |
| SD |
food intake rate |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70.0 days-84.0 days |
6 |
24.6 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84859 |
1602 |
| Crl:CD(SD) |
food intake rate |
standard diet |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
84.0 days
| 19 |
24.7 |
g/d |
0.48 |
2.1 |
unspecified method |
0.0 |
|
|
|
|
|
|
85290 |
1604 |
| F344/NHsd |
serum alanine aminotransferase activity level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood alanine transaminase amount |
male |
123.0 days-267.0 days |
8 |
109.3 |
U/l |
14.3 |
40.45 |
unspecified method |
0.0 |
|
|
|
|
|
|
84712 |
1599 |
| F344/NHsd |
serum total protein level |
fasting (for 16 hours) then acetaminophen (800 mg/kg) (for 4 hours) |
Mach J, et al., J Gerontol A Biol Sci Med Sci. 2013 Jul 17. |
blood total protein amount |
male |
714.0 days-882.0 days |
5 |
592.0 |
g/dl |
13.0 |
29.07 |
unspecified method |
0.0 |
|
|
|
|
|
|
84730 |
1599 |
| SD |
food intake rate |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
57.0 days-71.0 days |
6 |
35.0 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84825 |
1602 |
| SD |
food intake rate |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
male |
70.0 days-84.0 days |
6 |
32.4 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84831 |
1602 |
| SD |
food intake rate |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
eating behavior trait |
female |
70.0 days-84.0 days |
6 |
25.7 |
g/d |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
84863 |
1602 |
| SD |
blood differential white blood cell count |
acetaminophen (250 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71.0 days-85.0 days |
6 |
8.83 |
x 1000 cells/ul |
1.33 |
3.25 |
unspecified method |
0.0 |
|
|
|
|
|
|
84902 |
1602 |
| SD |
blood differential white blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
85.0 days-99.0 days |
6 |
8.24 |
x 1000 cells/ul |
0.77 |
1.88 |
unspecified method |
0.0 |
|
|
|
|
|
|
84906 |
1602 |
| SD |
blood differential white blood cell count |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
leukocyte quantity |
female |
71.0 days-85.0 days |
6 |
9.48 |
x 1000 cells/ul |
0.6 |
1.46 |
unspecified method |
0.0 |
|
|
|
|
|
|
84905 |
1602 |
| SD |
red blood cell count |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
71.0 days-85.0 days |
6 |
8.93 |
x 10E6 cells/ul |
0.23 |
0.56 |
unspecified method |
0.0 |
|
|
|
|
|
|
84911 |
1602 |
| SD |
red blood cell count |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
female |
85.0 days-99.0 days |
6 |
8.77 |
x 10E6 cells/ul |
0.2 |
0.49 |
unspecified method |
0.0 |
|
|
|
|
|
|
84913 |
1602 |
| SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
85.0 days-99.0 days |
6 |
45.18 |
% |
0.87 |
2.13 |
unspecified method |
0.0 |
|
|
|
|
|
|
84956 |
1602 |
| SD |
hematocrit |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
45.1 |
% |
0.49 |
1.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
84954 |
1602 |
| SD |
hematocrit |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte quantity |
male |
71.0 days-85.0 days |
6 |
44.05 |
% |
0.46 |
1.13 |
unspecified method |
0.0 |
|
|
|
|
|
|
84953 |
1602 |
| HanTac:WH |
number of blastocysts/embryos lost postimplantation to litter size ratio |
bisphenol A (0.025 mg/kg/d) (for 14 days) |
Christiansen S, et al., Reproduction. 2014 Mar 2;147(4):477-87. doi: 10.1530/REP-13-0377. Print 2014. |
embryonic growth trait |
female |
days
| 21 |
8.0 |
% |
2.23 |
10.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
96589 |
1559 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (100 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
7.6 |
% |
0.2 |
0.45 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96885 |
1719 |
| SS-Chr 12BN.SS-(D12Hmgc3-D12Hmgc6)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (140 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
5 |
6.5 |
% |
0.3 |
0.67 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96887 |
1719 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (80 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
9.5 |
% |
0.4 |
1.39 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96892 |
1719 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (100 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
8.6 |
% |
0.3 |
1.04 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96893 |
1719 |
| SS.BN-(D12Hmgc3-AU047911)/Mcwi |
artery wall thickness to artery inner diameter ratio |
controlled sodium content diet (0.3 %) then controlled ex vivo artery perfusion pressure (140 mmHg) |
Prisco SZ, et al., Am J Physiol Heart Circ Physiol. 2014 Oct 15;307(8):H1103-10. doi: 10.1152/ajpheart.00464.2014. Epub 2014 Aug 22. |
mesenteric artery morphology trait |
male |
63.0 days-70.0 days |
12 |
7.5 |
% |
0.3 |
1.04 |
unspecified method |
0.0 |
|
|
|
|
|
mesenteric artery morphology trait |
96895 |
1719 |
| CrljJcl:SD |
bisphenol A drink intake rate |
gestation (for 14 days) then controlled bisphenol A content drinking water (0.01 mg/l) (for 3 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
days
| 8 |
47.35 |
ml/d |
2.64 |
7.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
75886 |
1539 |
| Crl:SD |
food intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) (between 21 and 35 days) then controlled fructose content diet (66 %) (between 14 and 28 days) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
63.0 days-77.0 days |
10 |
24.0 |
g/d |
0.4 |
1.26 |
unspecified method |
0.0 |
|
|
|
|
FT |
|
75873 |
1540 |
| Crl:SD |
food intake rate |
controlled metformin content drinking water (350-500 mg/kg/d) |
Verma S, et al., J Pharmacol Exp Ther. 1994 Dec;271(3):1334-7. |
eating behavior trait |
male |
42.0 days
| 8 |
17.0 |
g/d |
0.2 |
0.57 |
unspecified method |
0.0 |
|
|
|
|
CT |
|
75878 |
1540 |
| CrljJcl:SD |
water drink intake rate |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
70.0 days
| 15 |
23.71 |
ml/d |
1.33 |
5.15 |
unspecified method |
0.0 |
|
|
|
|
|
|
75987 |
1539 |
| CrljJcl:SD |
sucrose drink intake volume |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
70.0 days
| 15 |
49.8 |
ml/d |
2.99 |
11.58 |
unspecified method |
0.0 |
|
|
|
|
|
|
75999 |
1539 |
| CrljJcl:SD |
water drink intake rate |
controlled in utero environment (for 10 days) then controlled bisphenol A content drinking water (0.1 mg/l) (for 31 days) then maternal milk (for 21 days) then controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
female |
42.0 days
| 15 |
29.68 |
ml/d |
1.01 |
3.91 |
unspecified method |
0.0 |
|
|
|
|
|
|
75995 |
1539 |
| CrljJcl:SD |
sucrose intake volume to total fluid intake volume ratio |
controlled sucrose content drinking water (15 %) (for 21 days) and water (for 21 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
drinking behavior trait |
male |
42.0 days
| 15 |
51.4 |
% |
2.76 |
10.69 |
unspecified method |
0.0 |
|
|
|
|
|
|
76010 |
1539 |
| SD |
blood hemoglobin level |
acetaminophen (500 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71.0 days-85.0 days |
6 |
11.9 |
g/dl |
0.16 |
0.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
84947 |
1602 |
| SD |
blood hemoglobin level |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
blood hemoglobin amount |
female |
71.0 days-85.0 days |
6 |
11.28 |
g/dl |
0.41 |
1.01 |
unspecified method |
0.0 |
|
|
|
|
|
|
84945 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
acetaminophen (1000 mg/kg) (for 28 days) |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
71.0 days-85.0 days |
6 |
11.87 |
% |
0.18 |
0.44 |
unspecified method |
0.0 |
|
|
|
|
|
|
84966 |
1602 |
| SD |
red blood cell distribution width-coefficient of variation |
control condition |
Venkatesan PS, et al., Biol Pharm Bull. 2014 Apr 5. |
erythrocyte size trait |
male |
85.0 days-99.0 days |
6 |
11.9 |
% |
0.18 |
0.45 |
unspecified method |
0.0 |
|
|
|
|
|
|
84967 |
1602 |
| Crl:CD(SD) |
food intake rate |
standard diet and restricted feeding (4 h) then acetaminophen (500 mg/kg) (for 56 days) |
Kondo K, et al., J Toxicol Sci. 2012;37(5):911-29. |
eating behavior trait |
male |
126.0 days
| 8 |
18.7 |
g/d |
1.45 |
4.1 |
unspecified method |
0.0 |
|
|
|
|
|
|
85475 |
1604 |
| CrljJcl:SD |
food intake rate |
controlled sucrose content drinking water (15 %) (for 49 days) and water (for 49 days) |
Xu X, et al., Neurotoxicol Teratol. 2011 Jul-Aug;33(4):458-63. doi: 10.1016/j.ntt.2011.06.002. Epub 2011 Jun 17. |
eating behavior trait |
female |
70.0 days
| 15 |
13.05 |
g/d |
1.89 |
7.32 |
unspecified method |
0.0 |
|
|
|
|
|
|
75937 |
1539 |
| W/Nin |
food intake rate |
controlled retinyl palmitate content diet (2.6 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
18.9 |
g/d |
0.57 |
1.4 |
unspecified method |
0.0 |
|
|
|
|
|
|
96725 |
1660 |
| W/Nin |
food intake rate |
controlled retinyl palmitate content diet (52 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
19.4 |
g/d |
2.15 |
5.27 |
unspecified method |
0.0 |
|
|
|
|
|
|
96727 |
1660 |
| W-LeprfaNin |
food intake rate |
controlled retinyl palmitate content diet (129 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
eating behavior trait |
male |
284.0 days
| 6 |
26.8 |
g/d |
0.6 |
1.47 |
unspecified method |
0.0 |
|
|
|
|
|
|
96732 |
1660 |
| W-LeprfaNin |
plasma glucose level |
controlled retinyl palmitate content diet (129 mg/kg) (between 36 and 42 days) then fasting (for 12 hours) |
Tiruvalluru M, et al., Nutrition. 2013 Jan;29(1):298-304. doi: 10.1016/j.nut.2012.06.006. Epub 2012 Oct 2. |
blood glucose amount |
male |
284.0 days
| 6 |
137.7 |
mg/dl |
7.02 |
17.2 |
unspecified method |
0.0 |
|
|
|
|
|
|
96740 |
1660 |
| Y59/Zgd |
bone ash content |
vitamin A (80 mg/kg/d) (for 14 days) and alendronate (40 mg/kg/d) (for 14 days) |
Orsolic N, et al., Eur J Nutr. 2014 Aug;53(5):1217-27. doi: 10.1007/s00394-013-0622-7. Epub 2013 Nov 23. |
bone mineral mass |
female |
105.0 days
| 10 |
0.65 |
g |
0.02 |
0.05 |
unspecified method |
0.0 |
|
|
|
|
right |
|
97404 |
1758 |
| SD |
food intake rate |
unilateral nephrectomy (for 28 days) |
Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. |
eating behavior trait |
male |
days
| 8 |
19.0 |
g/d |
2.83 |
8.0 |
unspecified method |
0.0 |
unx |
28 |
days |
|
|
|
101611 |
2602 |
| SS-Renem1Mcwi-/- |
creatinine clearance to total kidney weight ratio |
controlled sodium content diet (0.4 %) (for 42 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
glomerular filtration trait |
male |
63.0 days
| 8 |
0.33 |
ml/min/g |
0.02 |
0.06 |
unspecified method |
0.0 |
|
|
|
|
|
|
98351 |
2038 |
| SS-Renem1Mcwi+/- |
creatinine clearance to total kidney weight ratio |
controlled sodium content diet (0.4 %) (for 42 days) |
Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. |
glomerular filtration trait |
male |
63.0 days
| 9 |
0.83 |
ml/min/g |
0.08 |
0.24 |
unspecified method |
0.0 |
|
|
|
|
|
|
98350 |
2038 |
| F344 |
mean arterial blood pressure |
control condition |
Westlund KN, et al., Neuroscience. 2014 Mar 14;262:165-75. doi: 10.1016/j.neuroscience.2013.12.043. Epub 2014 Jan 3. |
arterial blood pressure trait |
male |
days
| 2 |
111.04 |
mmHg |
|
|
unspecified method |
0.0 |
|
|
|
|
|
|
105568 |
3018 |
| SHR-Chr 6MWF/Rkb |
kidney glomerulus count |
control condition |
Schulz A, etal., Physiol Genomics. 2010 Jun. |
kidney glomerulus quantity |
male |
28.0 days
| |
33868.0 |
null |
1812.0 |
|
unspecified method |
0.0 |
|
|
|
|
CMO:0000536- error: no unit |
|
109027 |
3116 |
| SHRSP/A3N |
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 112 days) and controlled fat content diet (24.5 %) (for 112 days) and controlled enrasentan content diet (1200 ppm) (for 112 days) |
Willette RN, etal., J Cardiovasc Pharmacol. 2001 Oct;38(4):606-17. doi: 10.1097/00005344-200110000-00013. |
total life span |
male |
182.0 days-210.0 days |
20 |
5.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of deaths related to left ventricular hypertrophy to total study population during a period of time (CMO:0003810) |
|
107935 |
3100 |
| ISIAH |
diastolic blood pressure |
control condition |
Shurligina AV, et al., Bull Exp Biol Med. 2013 Aug;155(4):421-4. doi: 10.1007/s10517-013-2167-4. |
arterial blood pressure trait |
male |
150.0 days-180.0 days |
10 |
111.0 |
mmHg |
9.7 |
30.67 |
unspecified method |
0.0 |
|
|
|
|
|
|
107673 |
3096 |
| SHRSP/A3NCrl |
ratio of survivors of severe albuminuria to total study population during a period of time |
controlled sodium chloride content drinking water (1 %) (for 91 days) and controlled fat content diet (24.5 %) (for 91 days) then controlled SB-239063 content diet (1200 ppm) (for 35 days) |
Lenhard SC, etal., J Pharmacol Exp Ther. 2003 Dec;307(3):939-46. doi: 10.1124/jpet.103.057398. Epub 2003 Oct 15. |
life span trait |
male |
161.0 days-175.0 days |
10 |
80.0 |
% |
|
|
unspecified method |
0.0 |
|
|
|
|
ratio of survivors of severe albuminuria to total study population during a period of time (CMO:0003630) |
|
109031 |
3083 |