| F344/DuCrl |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
|
5.14 |
ml/min/g |
0.35 |
1.1 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45892 |
461 |
| F344/DuCrl |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
8 |
|
10.67 |
ml/min/g |
1.93 |
5.44 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45899 |
461 |
| F344/DuCrl |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
55.89 |
% |
2.3 |
7.26 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47885 |
461 |
| F344/DuCrl |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
|
8.2 |
ml/min/g |
0.66 |
2.1 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46177 |
461 |
| F344/DuCrl |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49.0 days-63.0 days |
10 |
|
0.44 |
IU/g |
0.04 |
0.12 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45233 |
461 |
| F344/DuCrl |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
9 |
|
11.01 |
ml/min/g |
0.8 |
2.41 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46184 |
461 |
| F344/DuCrl |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
58.95 |
% |
4.3 |
13.59 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45855 |
461 |
| F344/DuCrl |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
8 |
|
11.31 |
ml/min/g |
0.95 |
2.69 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46160 |
461 |
| F344/DuCrl |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
|
14.79 |
ml/min/g |
1.06 |
3.37 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45084 |
461 |
| F344/DuCrl |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49.0 days-63.0 days |
9 |
|
0.54 |
IU/g |
0.06 |
0.18 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45240 |
461 |
| F344/DuCrl |
percent change in arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
9 |
post-ischemic value/pre-ischemic value x 100% |
71.83 |
% |
10.26 |
30.79 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45862 |
461 |
| F344/DuCrl |
arterial blood flow rate |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
male |
49.0 days-63.0 days |
10 |
|
8.78 |
ml/min/g |
0.3 |
0.94 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
46153 |
461 |
| F344/DuCrl |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49.0 days-63.0 days |
8 |
|
7.12 |
IU/g |
0.82 |
2.31 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47181 |
461 |
| F344/DuCrl |
arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
10 |
|
17.24 |
ml/min/g |
0.66 |
2.08 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
45091 |
461 |
| F344/DuCrl |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49.0 days-63.0 days |
10 |
|
0.38 |
IU/g |
0.05 |
0.16 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48380 |
461 |
| F344/DuCrl |
percent change in arterial blood flow rate |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
arterial blood flow trait |
female |
49.0 days-63.0 days |
10 |
post-ischemic value/pre-ischemic value x 100% |
56.39 |
% |
7.12 |
22.52 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47892 |
461 |
| F344/DuCrl |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled oxygen content Kreb's solution perfusate (for 0.5 hours) then perfusate suspended (for 0.4 hours) then controlled oxygen content Kreb's solution perfusate (for 0.7 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
male |
49.0 days-63.0 days |
10 |
|
5.03 |
IU/g |
0.73 |
2.3 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
47176 |
461 |
| F344/DuCrl |
heart effluent lactate dehydrogenase activity level normalized to heart weight |
controlled air oxygen content (12 %) (for 14 days) then controlled oxygen content Kreb's solution perfusate (for 0.5 hours) |
PhysGen Cardiac data |
heart lactate dehydrogenase activity |
female |
49.0 days-63.0 days |
10 |
|
0.56 |
IU/g |
0.05 |
0.17 |
isolated perfused heart effluent collection |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
48387 |
461 |