Phenominer Database Results (476 results)

 
 
How to display a graph
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SS/JrHsdMcwi urine fractional sodium excretion controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (150 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (170-175 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine sodium amount male 70.0 days 10 3.91 % 0.85 2.69 flame atomic emission spectrometry 1200.0 Fractional sodium excretion 64935 272
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 7.93 mEq/d 0.88 2.77 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51884 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 7.96 mEq/d 0.5 1.4 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51887 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 12.61 mEq/d 0.77 2.17 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51885 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 12.4 mEq/d 1.43 4.05 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52011 481
FHH-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 18.34 mEq/d 2.1 5.55 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52784 482
FHH-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 23.17 mEq/d 2.06 5.05 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52786 482
FHH-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 12.48 mEq/d 2.12 5.19 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52787 482
FHH-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 21.06 mEq/d 2.21 7.33 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52789 482
FHH-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 15.39 mEq/d 2.33 6.6 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52791 482
FHH-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 14.56 mEq/d 2.3 6.52 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52790 482
FHH-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 17.11 mEq/d 1.28 3.83 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52794 482
FHH-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 19.48 mEq/d 1.49 4.46 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52807 482
FHH-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 5 17.74 mEq/d 4.06 9.07 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52806 482
FHH-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 19.66 mEq/d 2.76 7.3 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52815 482
FHH-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 14.46 mEq/d 2.21 6.62 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52818 482
LE/BluGill urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 7 1.18 mEq/d 0.06 0.15 flame atomic emission spectrometry urine potassium analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52926 482
SS-Chr 14BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 11 0.88 mEq/d 0.09 0.29 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52929 482
SS-Chr 9BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 1.44 mEq/d 0.12 0.39 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52931 482
SS-Chr 7BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 11 1.19 mEq/d 0.07 0.24 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52938 482
SS-Chr 5BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 8 1.03 mEq/d 0.09 0.27 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52940 482
SS-Chr YBN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 17 1.4 mEq/d 0.1 0.4 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52955 482
SS/JrHsdMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 64 1.29 mEq/d 0.06 0.5 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52957 482
SS/JrHsdMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 11 1.15 mEq/d 0.05 0.18 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52963 482
SS-Chr 2BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 1.47 mEq/d 0.18 0.58 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52975 482
FHH-Chr 8BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 4 1.17 mEq/d 0.1 0.2 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52305 482
FHH-Chr 13BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 0.96 mEq/d 0.16 0.47 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52306 482
FHH-Chr 18BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 0.66 mEq/d 0.11 0.33 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52312 482
FHH-Chr 14BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 8 2.67 mEq/d 0.79 2.22 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52316 482
FHH-Chr 1BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 1.27 mEq/d 0.08 0.25 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52321 482
BN/NHsdMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 8 1.06 mEq/d 0.04 0.12 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52332 482
FHH-Chr 7BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 11 1.54 mEq/d 0.41 1.36 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52336 482
SS-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 20.45 mEq/d 2.19 5.79 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52749 482
SS-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 20 8.83 mEq/d 0.82 3.65 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52753 482
SS-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 20.07 mEq/d 2.22 6.67 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52751 482
SS-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 20 15.6 mEq/d 1.69 7.57 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52762 482
SS-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 19 10.57 mEq/d 1.46 6.38 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52765 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 13 11.79 mEq/d 0.65 2.34 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52768 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 21 12.87 mEq/d 1.17 5.34 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52774 482
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 6.59 mEq/d 0.55 1.64 flame atomic emission spectrometry 50871 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 1.16 mEq/d 0.25 0.62 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51044 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 1.74 mEq/d 0.27 0.76 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51265 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 1.46 mEq/d 0.2 0.9 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51266 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 6 1.4 mEq/d 0.14 0.34 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51267 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.32 mEq/d 0.09 0.25 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51272 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 1.62 mEq/d 0.15 0.47 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51269 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 1.21 mEq/d 0.14 0.65 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51516 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 1.17 mEq/d 0.16 0.49 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51527 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 7.87 mEq/d 1.47 4.17 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51640 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 8.01 mEq/d 0.64 2.01 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51642 481
SS/JrHsdMcwi urine sodium excretion rate to body weight ratio controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine sodium amount male 70.0 days 10 0.52 uEq/min/g 0.12 0.38 flame atomic emission spectrometry 1200.0 urine sodium excretion rate to kidney weight ratio 64967 272
SS.LEW-(D5Rat130-D5Rat31)/JrMcwi urine fractional sodium excretion controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine sodium amount male 70.0 days 8 1.29 % 0.34 0.96 flame atomic emission spectrometry 1200 Fractional 64969 272
SS/JrHsdMcwi urine sodium excretion rate to body weight ratio controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (150 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (170-175 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine sodium amount male 70.0 days 10 2.58 uEq/min/g 0.68 2.15 flame atomic emission spectrometry 1200.0 urine sodium excretion rate to kidney weight ratio 64968 272
FHH/EurMcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77.0 days-91.0 days 7 6.6 mmol/l 0.41 1.09 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 38829 401
SS-Chr 16BN/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77.0 days-91.0 days 6 4.38 mmol/l 0.12 0.31 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 38830 401
FHH-Nr0b2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 6 4.63 mmol/l 0.16 0.4 flame atomic emission spectrometry 61289 527
FHH-Adipoqm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 9 4.97 mmol/l 0.14 0.43 flame atomic emission spectrometry 61290 527
FHH-Lcatm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 12 5.74 mmol/l 0.55 1.9 flame atomic emission spectrometry 61294 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 2 4.35 mmol/l 0.75 1.06 flame atomic emission spectrometry 61300 527
F344/NHsd serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 7 3.8 mmol/l 0.16 0.43 flame atomic emission spectrometry 61315 527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 7 3.91 mmol/l 0.18 0.48 flame atomic emission spectrometry 61321 527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 4 4.2 mmol/l 0.32 0.65 flame atomic emission spectrometry 61330 527
FHH-Ghsrm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 9 4.28 mmol/l 0.11 0.33 flame atomic emission spectrometry 61331 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 7 4.4 mmol/l 0.24 0.64 flame atomic emission spectrometry 61332 527
FHH-Egln3m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 6 4.82 mmol/l 0.22 0.55 flame atomic emission spectrometry 61340 527
FHH-Ghsrm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 15 5.35 mmol/l 0.29 1.11 flame atomic emission spectrometry 61339 527
FHH-Tlr4m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 8 4.75 mmol/l 0.29 0.81 flame atomic emission spectrometry 61352 527
SS-Cpt2m1Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 6 4.28 mmol/l 0.1 0.26 flame atomic emission spectrometry 61752 527
SS-Ghsrm3Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 1 3.4 mmol/l flame atomic emission spectrometry 61758 527
SS-Sod3m1Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 11 4.48 mmol/l 0.64 2.14 flame atomic emission spectrometry 61760 527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 5 135.4 mmol/l 1.75 3.91 flame atomic emission spectrometry 61778 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 2 141.5 mmol/l 1.5 2.12 flame atomic emission spectrometry 61782 527
BN-Tgfbr2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 3 137.33 mmol/l 1.67 2.89 flame atomic emission spectrometry 61777 527
FHH-F10m2Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 16 139.38 mmol/l 0.49 1.96 flame atomic emission spectrometry 61798 527
FHH-Htr1am1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 13 138.85 mmol/l 0.75 2.7 flame atomic emission spectrometry 61796 527
FHH-Ccr2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 8 140.0 mmol/l 1.27 3.59 flame atomic emission spectrometry 61800 527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 2 138.5 mmol/l 1.5 2.12 flame atomic emission spectrometry 61805 527
F344-DccTn(sb-T2/Bart3)2.205Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 4 139.75 mmol/l 3.3 6.6 flame atomic emission spectrometry 61810 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 7 138.86 mmol/l 0.7 1.86 flame atomic emission spectrometry 61814 527
FHH-Ghsrm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 15 141.8 mmol/l 0.35 1.37 flame atomic emission spectrometry 61821 527
FHH-Egln3m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 6 137.0 mmol/l 2.89 7.07 flame atomic emission spectrometry 61822 527
FHH-Egln3m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 14 139.36 mmol/l 1.32 4.96 flame atomic emission spectrometry 61836 527
BN/NHsdMcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 27 140.81 mmol/l 0.36 1.86 flame atomic emission spectrometry 61840 527
BN/NHsdMcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 44 141.27 mmol/l 0.43 2.86 flame atomic emission spectrometry 61839 527
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.3 mmol/l 1.8 4.41 flame atomic emission spectrometry 0.0 102234 2682
SS/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.6 mmol/l 2.4 5.88 flame atomic emission spectrometry 0.0 102241 2682
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.8 mmol/l 1.6 3.92 flame atomic emission spectrometry 0.0 102249 2682
SS/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 141.1 mmol/l 1.8 4.41 flame atomic emission spectrometry 0.0 102254 2682
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 16 12.7 mEq/d 1.39 5.55 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51886 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 19 11.47 mEq/d 0.98 4.28 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51882 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 10.9 mEq/d 0.8 2.54 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51894 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 10.76 mEq/d 0.53 1.6 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52019 481
FHH-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 1 10.05 mEq/d flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52785 482
FHH-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 8 26.38 mEq/d 1.83 5.17 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52795 482
FHH-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 11.86 mEq/d 2.45 7.36 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52797 482
FHH-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 12.0 mEq/d 2.14 6.77 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52796 482
FHH-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 30.48 mEq/d 3.7 9.8 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52804 482
FHH-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 8.59 mEq/d 1.43 3.78 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52808 482
FHH-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 14.41 mEq/d 2.04 6.13 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52813 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 15.99 mEq/d 2.14 7.08 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52821 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 12 1.33 mEq/d 0.07 0.25 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52928 482
SS-Chr 6BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 1.09 mEq/d 0.17 0.5 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52935 482
SS-Chr 17BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 1.49 mEq/d 0.07 0.22 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52937 482
SS-Chr 5BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 1.33 mEq/d 0.09 0.28 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52942 482
SS-Chr 16BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 1.75 mEq/d 0.11 0.34 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52948 482
SS-Chr 20BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 0.95 mEq/d 0.07 0.2 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52951 482
SS-Chr 11BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 19 0.99 mEq/d 0.07 0.3 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52952 482
SS-Chr 18BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 0.83 mEq/d 0.07 0.2 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52956 482
SS-Chr 1BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 19 0.93 mEq/d 0.06 0.27 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52961 482
SS-Chr 19BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 8 0.81 mEq/d 0.08 0.23 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52967 482
SS-Chr 2BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 0.91 mEq/d 0.08 0.25 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52969 482
BN/NHsdMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 1.47 mEq/d 0.11 0.36 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52972 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 21 1.14 mEq/d 0.05 0.23 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52970 482
FHH-Chr 15BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 1.44 mEq/d 0.05 0.16 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52293 482
FHH-Chr 14BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 6 2.0 mEq/d 0.31 0.75 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52300 482
FHH-Chr 19BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 8 0.98 mEq/d 0.09 0.24 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52302 482
FHH-Chr 6BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 8 1.1 mEq/d 0.06 0.16 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52303 482
FHH-Chr 20BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 1.25 mEq/d 0.08 0.26 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52310 482
FHH/EurMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 48 1.26 mEq/d 0.05 0.38 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52313 482
FHH-Chr 15BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 1.1 mEq/d 0.16 0.43 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52314 482
FHH-Chr 4BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 5 1.12 mEq/d 0.12 0.27 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52322 482
FHH-Chr 16BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 0.95 mEq/d 0.1 0.26 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52320 482
FHH-Chr 4BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 0.97 mEq/d 0.1 0.29 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52325 482
FHH-Chr 9BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 6 1.5 mEq/d 0.13 0.32 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52335 482
FHH-Chr 1BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 0.94 mEq/d 0.09 0.27 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52338 482
SS-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 9.79 mEq/d 2.32 6.96 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52739 482
SS-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 20.45 mEq/d 2.52 6.66 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52743 482
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 15.46 mEq/d 2.53 7.6 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52738 482
SS-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 16.93 mEq/d 1.84 5.21 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52744 482
SS-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 14.58 mEq/d 1.41 4.68 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52745 482
SS-Chr YBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 17 13.93 mEq/d 1.18 4.86 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52759 482
SS-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 15.25 mEq/d 2.49 6.59 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52766 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 25.2 mEq/d 2.71 8.56 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52776 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 21 15.57 mEq/d 1.26 5.76 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52777 482
FHH-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 21.01 mEq/d 1.52 4.55 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52781 482
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 10.64 mEq/d 1.12 3.17 flame atomic emission spectrometry 50872 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 6 1.16 mEq/d 0.02 0.04 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51047 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 1.46 mEq/d 0.11 0.36 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51270 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 11 0.78 mEq/d 0.1 0.33 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51271 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 12.55 mEq/d 1.2 3.38 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51298 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 4.93 mEq/d 0.54 1.53 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51295 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 5 12.15 mEq/d 0.74 1.66 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51296 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 1.82 mEq/d 0.27 0.81 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51362 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.68 mEq/d 0.25 0.74 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51364 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.3 mEq/d 0.09 0.26 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51522 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 7 0.91 mEq/d 0.11 0.28 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51519 481
SS.LEW-(D5Rat130-D5Rat31)/JrMcwi urine fractional sodium excretion controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (150 mmHg) (for 0.3 hours) then controlled in situ renal perfusion pressure (170-175 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine sodium amount male 70.0 days 8 7.84 % 0.82 2.32 flame atomic emission spectrometry 1200 Fractional 64970 272
SS-Cpt2m1Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 6 146.83 mmol/l 0.6 1.47 flame atomic emission spectrometry 60900 527
SS-Klf4m3Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 7 135.29 mmol/l 0.89 2.36 flame atomic emission spectrometry 60903 527
SS-Ghsrm3Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 1 137.0 mmol/l flame atomic emission spectrometry 60906 527
FHH-Lcatm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 15 4.55 mmol/l 0.17 0.65 flame atomic emission spectrometry 61301 527
BN-Tgfbr2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 7 4.7 mmol/l 0.17 0.45 flame atomic emission spectrometry 61306 527
FHH-Ccr2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 7 6.53 mmol/l 0.75 1.99 flame atomic emission spectrometry 61318 527
F344/NHsd serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 4 4.8 mmol/l 0.83 1.65 flame atomic emission spectrometry 61324 527
FHH-F10m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 10 5.15 mmol/l 0.24 0.75 flame atomic emission spectrometry 61326 527
FHH-Nr4a1m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 10 4.7 mmol/l 0.36 1.14 flame atomic emission spectrometry 61327 527
FHH/EurMcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 25 4.45 mmol/l 0.15 0.74 flame atomic emission spectrometry 61333 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 2 3.4 mmol/l 0.2 0.28 flame atomic emission spectrometry 61336 527
F344-DccTn(sb-T2/Bart3)2.205Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 6 3.87 mmol/l 0.25 0.6 flame atomic emission spectrometry 61341 527
FHH-Adipoqm3Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 6 4.72 mmol/l 0.34 0.84 flame atomic emission spectrometry 61342 527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 3 3.3 mmol/l 0.35 0.61 flame atomic emission spectrometry 61338 527
FHH-Adipoqm3Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 5 6.06 mmol/l 0.49 1.09 flame atomic emission spectrometry 61343 527
FHH-Adra1am1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 8 5.39 mmol/l 0.27 0.75 flame atomic emission spectrometry 61345 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 3 4.17 mmol/l 0.27 0.46 flame atomic emission spectrometry 61349 527
FHH-Tlr4m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 5 5.52 mmol/l 0.43 0.96 flame atomic emission spectrometry 61348 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 2 3.55 mmol/l 0.05 0.07 flame atomic emission spectrometry 61353 527
SS-Klf4m3Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 7 4.39 mmol/l 0.22 0.59 flame atomic emission spectrometry 61755 527
SS/JrHsdMcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 40 4.12 mmol/l 0.12 0.77 flame atomic emission spectrometry 61753 527
SS-Klf4m3Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 8 4.38 mmol/l 0.29 0.82 flame atomic emission spectrometry 61756 527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 6 143.33 mmol/l 0.8 1.97 flame atomic emission spectrometry 61781 527
FHH-Agtr1bm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 14 140.21 mmol/l 0.5 1.89 flame atomic emission spectrometry 61786 527
FHH-Adipoqm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 8 139.38 mmol/l 0.91 2.56 flame atomic emission spectrometry 61789 527
FHH-Ccr2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 5 138.2 mmol/l 1.74 3.9 flame atomic emission spectrometry 61792 527
FHH-F10m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 11 136.09 mmol/l 0.81 2.7 flame atomic emission spectrometry 61793 527
FHH-Procm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 10 140.6 mmol/l 1.5 4.74 flame atomic emission spectrometry 61802 527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 7 141.71 mmol/l 1.48 3.9 flame atomic emission spectrometry 61803 527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 1 142.0 mmol/l flame atomic emission spectrometry 61811 527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 4 143.5 mmol/l 1.55 3.11 flame atomic emission spectrometry 61812 527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 1 143.0 mmol/l flame atomic emission spectrometry 61817 527
F344-Fam19a2Tn(sb-T2/Bart3)2.184Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 2 140.0 mmol/l 1.0 1.41 flame atomic emission spectrometry 61818 527
BN-Lcatm3Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 1 141.0 mmol/l flame atomic emission spectrometry 61819 527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 2 142.5 mmol/l 1.5 2.12 flame atomic emission spectrometry 61832 527
FHH-Tlr4m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 7 142.43 mmol/l 2.59 6.85 flame atomic emission spectrometry 61830 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 3 140.0 mmol/l 0.0 0.0 flame atomic emission spectrometry 61831 527
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 139.6 mmol/l 2.1 5.14 flame atomic emission spectrometry 0.0 102233 2682
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.4 mmol/l 1.4 3.43 flame atomic emission spectrometry 0.0 102236 2682
SS/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.2 mmol/l 2.1 5.14 flame atomic emission spectrometry 0.0 102242 2682
SS/JrHsdMcwi urine fractional sodium excretion controlled in situ renal perfusion pressure (125-130 mmHg) (for 0.3 hours) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. urine sodium amount male 70.0 days 10 1.3 % 0.37 1.17 flame atomic emission spectrometry 1200.0 Fractional 64937 272
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 12.02 mEq/d 0.55 1.55 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51942 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 6 14.22 mEq/d 0.96 2.35 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52013 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 9.28 mEq/d 1.19 5.33 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52012 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 3 11.47 mEq/d 1.92 3.33 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52014 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 11 7.72 mEq/d 1.23 4.07 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52017 481
FHH-Chr 8BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 18.52 mEq/d 2.14 5.67 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52782 482
FHH-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 23.14 mEq/d 3.44 8.42 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52788 482
FHH-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 25.89 mEq/d 2.25 5.95 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52792 482
FHH-Chr 8BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 4 21.15 mEq/d 6.39 12.78 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52793 482
FHH-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 14.16 mEq/d 1.75 5.8 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52799 482
FHH-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 4 7.48 mEq/d 3.66 7.33 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52803 482
FHH-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 5 11.31 mEq/d 3.21 7.18 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52810 482
FHH-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 10.12 mEq/d 2.33 5.71 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52816 482
FHH-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 4 18.03 mEq/d 2.64 5.28 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52814 482
FHH-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 5 13.65 mEq/d 2.04 4.57 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52817 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 8 19.07 mEq/d 1.63 4.62 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52820 482
FHH-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 19.96 mEq/d 1.86 4.56 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52823 482
FHH-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 8 8.0 mEq/d 3.18 9.0 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52825 482
SS-Chr 17BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 1.16 mEq/d 0.11 0.28 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52939 482
SS-Chr 3BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 1.14 mEq/d 0.14 0.41 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52947 482
SS-Chr 15BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 7 1.97 mEq/d 0.89 2.35 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52945 482
SS-Chr 3BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 1.04 mEq/d 0.11 0.3 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52950 482
SS-Chr 13BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 16 1.06 mEq/d 0.09 0.35 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52953 482
SS-Chr XBN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 1.27 mEq/d 0.14 0.38 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52959 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 13 0.87 mEq/d 0.05 0.17 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52964 482
SS-Chr 12BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 1.61 mEq/d 0.08 0.24 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52966 482
SS-Chr 4BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 8 1.1 mEq/d 0.1 0.27 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52968 482
BN/NHsdMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 21 0.95 mEq/d 0.05 0.24 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52973 482
FHH-Chr 8BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 1.19 mEq/d 0.08 0.22 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52294 482
FHH-Chr 19BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 7 1.17 mEq/d 0.08 0.21 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52296 482
FHH-Chr 3BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 1 0.53 mEq/d flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52297 482
FHH-Chr 2BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 6 0.87 mEq/d 0.13 0.32 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52299 482
FHH-Chr 5BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 6 1.25 mEq/d 0.12 0.3 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52298 482
FHH-Chr 12BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 11 1.07 mEq/d 0.06 0.21 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52311 482
FHH-Chr YBN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 5 1.47 mEq/d 0.06 0.14 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52317 482
FHH-Chr 17BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 14 0.99 mEq/d 0.05 0.2 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52324 482
FHH-Chr 2BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 5 1.34 mEq/d 0.07 0.15 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52318 482
BN/NHsdMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 11 0.77 mEq/d 0.09 0.29 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52333 482
FHH-Chr 16BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 8 1.2 mEq/d 0.14 0.39 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52337 482
SS-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 12.59 mEq/d 2.85 9.44 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52731 482
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 18.68 mEq/d 2.46 7.78 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52735 482
SS-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 19.23 mEq/d 1.2 3.81 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52742 482
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 25.69 mEq/d 2.48 7.85 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52752 482
SS-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 19 13.54 mEq/d 1.29 5.61 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52756 482
SS-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 9.12 mEq/d 2.82 7.99 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52771 482
SS-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 12.32 mEq/d 1.69 5.33 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52773 482
SS-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 11.82 mEq/d 1.51 4.27 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52772 482
FHH-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 12.16 mEq/d 2.29 7.24 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52780 482
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 1.37 mEq/d 0.05 0.15 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51046 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.07 mEq/d 0.18 0.5 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51049 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.25 mEq/d 0.15 0.43 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51264 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 3 1.36 mEq/d 0.12 0.21 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51268 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 2.11 mEq/d 0.17 0.54 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51274 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 3 0.95 mEq/d 0.15 0.26 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51275 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 5 9.79 mEq/d 1.85 4.14 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51294 481
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 16 0.74 mEq/d 0.11 0.43 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51399 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 1.06 mEq/d 0.11 0.35 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51518 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.08 mEq/d 0.16 0.45 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51521 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.05 mEq/d 0.12 0.36 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51528 481
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 1.07 mEq/d 0.08 0.24 flame atomic emission spectrometry 50436 481
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 1.5 mEq/d 0.11 0.34 flame atomic emission spectrometry 50438 481
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 1.16 mEq/d 0.2 0.56 flame atomic emission spectrometry 50439 481
SS/JrHsdMcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 40 143.98 mmol/l 0.37 2.33 flame atomic emission spectrometry 60901 527
SS-Sod3m1Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 11 146.55 mmol/l 2.14 7.09 flame atomic emission spectrometry 60908 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 1 3.4 mmol/l flame atomic emission spectrometry 61293 527
FHH-Tgfbr2m2Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 12 5.18 mmol/l 0.12 0.41 flame atomic emission spectrometry 61292 527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 3 4.67 mmol/l 0.19 0.32 flame atomic emission spectrometry 61303 527
FHH-Tgfbr2m2Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 14 4.86 mmol/l 0.28 1.03 flame atomic emission spectrometry 61298 527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 5 3.74 mmol/l 0.14 0.31 flame atomic emission spectrometry 61308 527
FHH-Procm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 7 5.49 mmol/l 0.34 0.91 flame atomic emission spectrometry 61313 527
FHH-Htr1am1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 13 4.85 mmol/l 0.28 1.0 flame atomic emission spectrometry 61314 527
FHH-Nr4a1m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 11 4.84 mmol/l 0.2 0.68 flame atomic emission spectrometry 61319 527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 1 3.5 mmol/l flame atomic emission spectrometry 61317 527
FHH-F10m2Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 12 4.49 mmol/l 0.29 1.02 flame atomic emission spectrometry 61325 527
FHH-Procm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 7 6.89 mmol/l 1.38 3.65 flame atomic emission spectrometry 61320 527
F344-Lims1Tn(sb-T2/Bart3)2.169Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 2 4.95 mmol/l 0.65 0.92 flame atomic emission spectrometry 61323 527
SS/JrHsdMcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 17 3.85 mmol/l 0.07 0.31 flame atomic emission spectrometry 61759 527
FHH-Adipoqm2Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 12 138.5 mmol/l 0.65 2.24 flame atomic emission spectrometry 61773 527
FHH-Nr0b2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 6 138.33 mmol/l 1.43 3.5 flame atomic emission spectrometry 61771 527
FHH-Tgfbr2m2Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 12 140.0 mmol/l 0.44 1.54 flame atomic emission spectrometry 61774 527
FHH-Lcatm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 12 140.5 mmol/l 0.58 2.02 flame atomic emission spectrometry 61776 527
BN-Tgfbr2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 7 139.86 mmol/l 1.03 2.73 flame atomic emission spectrometry 61788 527
F344/NHsd serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 7 142.57 mmol/l 1.67 4.43 flame atomic emission spectrometry 61797 527
FHH-Procm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 8 138.75 mmol/l 0.96 2.71 flame atomic emission spectrometry 61795 527
FHH/EurMcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 25 140.32 mmol/l 0.56 2.81 flame atomic emission spectrometry 61815 527
BN-Lcatm3Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 2 143.0 mmol/l 1.0 1.41 flame atomic emission spectrometry 61816 527
FHH-Adra1am1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 8 141.25 mmol/l 0.77 2.19 flame atomic emission spectrometry 61827 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 4 142.25 mmol/l 0.75 1.5 flame atomic emission spectrometry 61828 527
FHH-Adra1am1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 9 139.0 mmol/l 0.69 2.06 flame atomic emission spectrometry 61829 527
FHH-Tlr4m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 9 138.44 mmol/l 0.56 1.67 flame atomic emission spectrometry 61834 527
F344-Erbb4Tn(sb-T2/Bart3)2.208Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 2 138.0 mmol/l 1.0 1.41 flame atomic emission spectrometry 61835 527
SS/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.7 mmol/l 2.2 5.39 flame atomic emission spectrometry 0.0 102244 2682
SR/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 139.6 mmol/l 1.4 3.43 flame atomic emission spectrometry 0.0 102250 2682
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 139.8 mmol/l 0.7 1.71 flame atomic emission spectrometry 0.0 102251 2682
SS/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 138.9 mmol/l 1.2 2.94 flame atomic emission spectrometry 0.0 102255 2682
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 11.22 mEq/d 0.95 2.86 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51888 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 7.15 mEq/d 0.51 1.6 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51890 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 11.63 mEq/d 1.0 3.17 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51893 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 13.2 mEq/d 1.8 4.41 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51892 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 18.33 mEq/d 0.61 1.92 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52015 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 12.03 mEq/d 0.87 2.47 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52018 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 13.71 mEq/d 0.45 1.42 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52016 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 13.82 mEq/d 1.3 4.11 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52020 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 3 12.33 mEq/d 1.71 2.97 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52021 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 16 14.02 mEq/d 1.77 7.07 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52783 482
FHH-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 21.52 mEq/d 1.69 5.36 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52798 482
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 48 18.43 mEq/d 0.86 5.95 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52801 482
FHH-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 17.44 mEq/d 3.27 8.66 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52802 482
FHH-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 14 11.64 mEq/d 1.13 4.21 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52812 482
FHH-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 21.2 mEq/d 2.45 6.01 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52819 482
LE/BluGill urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 16.09 mEq/d 2.02 6.07 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52827 482
FHH-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 11.87 mEq/d 2.05 6.48 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52826 482
LE/BluGill urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 1.09 mEq/d 0.1 0.29 flame atomic emission spectrometry urine potassium analysis Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52925 482
SS-Chr 10BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 11 1.26 mEq/d 0.21 0.69 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52927 482
SS-Chr 6BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 0.9 mEq/d 0.06 0.2 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52930 482
SS-Chr 14BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 7 1.17 mEq/d 0.12 0.33 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52933 482
SS-Chr 9BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 0.98 mEq/d 0.1 0.3 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52934 482
SS-Chr 10BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 0.75 mEq/d 0.08 0.26 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52936 482
SS-Chr 7BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 11 0.9 mEq/d 0.05 0.17 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52941 482
SS-Chr 15BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 0.99 mEq/d 0.14 0.36 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52946 482
SS-Chr 20BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 0.73 mEq/d 0.06 0.18 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52943 482
SS-Chr 16BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 0.94 mEq/d 0.1 0.3 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52944 482
SS-Chr 18BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 0.58 mEq/d 0.04 0.14 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52960 482
SS-Chr 19BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 6 1.38 mEq/d 0.14 0.34 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52965 482
SS-Chr XBN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 6 1.24 mEq/d 0.07 0.17 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52974 482
FHH/EurMcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 16 0.92 mEq/d 0.05 0.2 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52295 482
FHH-Chr 6BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 11 1.45 mEq/d 0.08 0.25 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52301 482
FHH-Chr 20BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 8 1.23 mEq/d 0.05 0.14 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52307 482
FHH-Chr 5BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 7 1.38 mEq/d 0.06 0.16 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52304 482
FHH-Chr 3BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 3 1.07 mEq/d 0.58 1.01 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52315 482
FHH-Chr 10BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 1.06 mEq/d 0.06 0.17 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52319 482
FHH-Chr 11BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 4 1.27 mEq/d 0.18 0.35 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52326 482
FHH-Chr XBN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 7 1.58 mEq/d 0.1 0.26 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52327 482
FHH-Chr 11BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 6 0.62 mEq/d 0.16 0.4 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52328 482
FHH-Chr XBN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 7 1.23 mEq/d 0.06 0.15 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52334 482
FHH-Chr 10BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 6 1.53 mEq/d 0.15 0.38 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52331 482
FHH-Chr 9BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 5 1.41 mEq/d 0.32 0.71 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52329 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 12 15.1 mEq/d 1.32 4.57 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52732 482
SS-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 11.08 mEq/d 1.72 5.43 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52734 482
SS-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 13.1 mEq/d 1.27 3.35 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52737 482
SS-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 9.59 mEq/d 2.03 6.43 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52740 482
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 12.8 mEq/d 1.99 5.96 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52747 482
SS-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 20.67 mEq/d 1.77 5.6 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52746 482
SS-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 14.44 mEq/d 3.52 9.31 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52750 482
SS-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 17.73 mEq/d 1.8 4.76 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52754 482
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 64 14.23 mEq/d 0.97 7.78 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52761 482
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 8.38 mEq/d 0.48 1.51 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52764 482
SS-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 16.97 mEq/d 1.49 3.94 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52763 482
SS-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 24.35 mEq/d 2.98 8.95 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52770 482
SS-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 14.43 mEq/d 4.03 9.86 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52769 482
SS-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 19.17 mEq/d 2.94 8.3 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52775 482
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 12.18 mEq/d 0.61 1.82 flame atomic emission spectrometry 50869 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 1.39 mEq/d 0.12 0.29 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51045 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.32 mEq/d 0.09 0.28 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51273 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.23 mEq/d 0.15 0.45 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51276 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 11.86 mEq/d 1.63 3.99 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51293 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 4 5.22 mEq/d 2.07 4.13 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51297 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 5.93 mEq/d 0.44 1.07 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51299 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.25 mEq/d 0.19 0.54 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51363 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 18 1.0 mEq/d 0.12 0.49 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51517 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 0.91 mEq/d 0.16 0.46 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51515 481
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 16 1.32 mEq/d 0.12 0.49 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51523 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 13.41 mEq/d 1.64 4.91 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51639 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 10.47 mEq/d 1.07 3.21 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51641 481
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 7 1.07 mEq/d 0.15 0.39 flame atomic emission spectrometry 50437 481
SS-Chr 16BN/Mcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77.0 days-91.0 days 7 4.56 mmol/l 0.11 0.28 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 38831 401
SS/JrHsdMcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount female 77.0 days-91.0 days 6 4.78 mmol/l 0.31 0.75 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 38833 401
SS-Sod3m1Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 10 141.2 mmol/l 1.18 3.74 flame atomic emission spectrometry 60902 527
FHH-Adipoqm2Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 10 4.57 mmol/l 0.24 0.77 flame atomic emission spectrometry 61291 527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 5 4.24 mmol/l 0.16 0.35 flame atomic emission spectrometry 61296 527
BN-Tgfbr2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 3 3.6 mmol/l 0.21 0.36 flame atomic emission spectrometry 61295 527
FHH-Agtr1bm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 14 4.05 mmol/l 0.13 0.47 flame atomic emission spectrometry 61304 527
FHH-Adipoqm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 8 5.99 mmol/l 0.53 1.51 flame atomic emission spectrometry 61307 527
FHH-Adipoqm2Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 3 5.27 mmol/l 0.55 0.95 flame atomic emission spectrometry 61309 527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 3 3.7 mmol/l 0.4 0.7 flame atomic emission spectrometry 61312 527
FHH-Htr1am1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 19 5.08 mmol/l 0.16 0.71 flame atomic emission spectrometry 61322 527
F344-Myo9aTn(sb-T2/Bart3)2.186Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 1 4.3 mmol/l flame atomic emission spectrometry 61329 527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 1 5.6 mmol/l flame atomic emission spectrometry 61335 527
BN-Lcatm3Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 1 4.6 mmol/l flame atomic emission spectrometry 61337 527
FHH/EurMcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 158 5.1 mmol/l 0.12 1.51 flame atomic emission spectrometry 61344 527
F344-AbatTn(sb-T2/Bart3)2.163Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 4 4.18 mmol/l 0.37 0.73 flame atomic emission spectrometry 61346 527
FHH-Adra1am1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 9 4.91 mmol/l 0.34 1.02 flame atomic emission spectrometry 61347 527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 2 4.1 mmol/l 0.2 0.28 flame atomic emission spectrometry 61350 527
FHH-Slc8a2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 10 8.31 mmol/l 1.52 4.8 flame atomic emission spectrometry 61351 527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 5 3.6 mmol/l 0.19 0.42 flame atomic emission spectrometry 61356 527
SS-Sod3m1Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 10 4.44 mmol/l 0.23 0.73 flame atomic emission spectrometry 61754 527
SS-Ghsrm3Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 2 3.55 mmol/l 0.15 0.21 flame atomic emission spectrometry 61751 527
SS-Cpt2m1Mcwi serum potassium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 1 4.1 mmol/l flame atomic emission spectrometry 61757 527
F344-Trpc4Tn(sb-T2/Bart3)2.192Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 1 144.0 mmol/l flame atomic emission spectrometry 61775 527
FHH-Tgfbr2m2Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 14 138.79 mmol/l 0.59 2.23 flame atomic emission spectrometry 61780 527
FHH-Nr0b2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 10 137.9 mmol/l 2.23 7.06 flame atomic emission spectrometry 61787 527
FHH-Adipoqm2Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 7 139.57 mmol/l 0.87 2.3 flame atomic emission spectrometry 61791 527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 5 140.6 mmol/l 1.63 3.65 flame atomic emission spectrometry 61790 527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 1 144.0 mmol/l flame atomic emission spectrometry 61799 527
FHH-Htr1am1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 21 138.71 mmol/l 0.57 2.61 flame atomic emission spectrometry 61804 527
F344/NHsd serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 4 147.25 mmol/l 2.95 5.91 flame atomic emission spectrometry 61806 527
F344-DccTn(sb-T2/Bart3)2.205Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 6 141.67 mmol/l 1.38 3.39 flame atomic emission spectrometry 61823 527
FHH/EurMcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 158 140.35 mmol/l 0.28 3.5 flame atomic emission spectrometry 61826 527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 5 140.6 mmol/l 1.47 3.29 flame atomic emission spectrometry 61838 527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 5 138.2 mmol/l 1.93 4.32 flame atomic emission spectrometry 61841 527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 4 142.5 mmol/l 0.87 1.73 flame atomic emission spectrometry 61842 527
SS/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 139.6 mmol/l 1.9 4.65 flame atomic emission spectrometry 0.0 102243 2682
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.7 mmol/l 0.9 2.2 flame atomic emission spectrometry 0.0 102252 2682
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 10.42 mEq/d 1.31 3.71 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51881 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 19 7.55 mEq/d 0.78 3.41 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51883 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 18 9.89 mEq/d 1.19 5.06 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51891 481
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 17 9.6 mEq/d 0.83 3.42 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51889 481
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 15 15.59 mEq/d 0.52 2.03 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51941 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 13.61 mEq/d 0.49 1.38 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52010 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 10.81 mEq/d 0.58 1.75 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52022 481
FHH-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 8.89 mEq/d 1.85 5.54 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52800 482
FHH-Chr YBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 5 16.71 mEq/d 3.54 7.91 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52805 482
FHH-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 19.31 mEq/d 1.16 3.66 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52809 482
FHH-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 14.04 mEq/d 2.22 7.02 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52811 482
FHH-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 14.23 mEq/d 3.75 12.43 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52824 482
FHH-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 20.79 mEq/d 0.9 2.37 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52822 482
LE/BluGill urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 23.29 mEq/d 1.27 3.37 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52828 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 0.95 mEq/d 0.12 0.39 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52932 482
SS-Chr 13BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 20 0.76 mEq/d 0.05 0.24 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52949 482
SS-Chr 1BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 20 1.07 mEq/d 0.08 0.34 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52958 482
SS-Chr 11BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 21 1.32 mEq/d 0.1 0.45 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52954 482
SS-Chr 4BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 7 1.08 mEq/d 0.21 0.56 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52962 482
SS-Chr 12BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 8 1.31 mEq/d 0.06 0.16 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52971 482
FHH-Chr 12BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 10 0.9 mEq/d 0.07 0.21 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52292 482
FHH-Chr 18BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 9 0.9 mEq/d 0.11 0.32 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52309 482
FHH-Chr 13BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 0.91 mEq/d 0.11 0.34 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52308 482
FHH-Chr 17BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount male 80.0 days-99.0 days 10 1.18 mEq/d 0.1 0.3 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52323 482
FHH-Chr 7BN/Mcwi urine potassium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine potassium amount female 80.0 days-99.0 days 9 1.08 mEq/d 0.2 0.61 flame atomic emission spectrometry urine potassium analysis Moms were fed Teklad, pups used in studies were fed Dyets 52330 482
SS-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 11.05 mEq/d 2.27 7.51 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52733 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 10.85 mEq/d 1.44 4.55 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52736 482
SS-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 15.57 mEq/d 1.84 5.52 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52741 482
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 8.36 mEq/d 1.42 4.02 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52748 482
SS-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 16 11.92 mEq/d 1.33 5.31 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52757 482
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 15.96 mEq/d 2.07 6.2 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52755 482
SS-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 21 15.6 mEq/d 1.58 7.24 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52758 482
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 12.51 mEq/d 0.99 2.97 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52760 482
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 18.24 mEq/d 1.67 5.53 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52767 482
SS-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 14.01 mEq/d 3.51 8.61 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52778 482
SS-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 18.08 mEq/d 2.1 6.64 flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52779 482
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 4.7 mEq/d 0.64 1.81 flame atomic emission spectrometry 50870 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 0.89 mEq/d 0.23 0.64 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51050 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 4 0.79 mEq/d 0.09 0.17 flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51048 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 1.24 mEq/d 0.13 0.4 flame atomic emission spectrometry 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51365 481
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 1.19 mEq/d 0.1 0.46 flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51398 481
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 16 1.23 mEq/d 0.16 0.63 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51520 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 5 0.8 mEq/d 0.21 0.46 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51526 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.03 mEq/d 0.18 0.54 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51524 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 18 1.11 mEq/d 0.13 0.54 flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51525 481
FHH/EurMcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77.0 days-91.0 days 7 5.73 mmol/l 0.33 0.88 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 38832 401
SS/JrHsdMcwi serum potassium level controlled air oxygen content (12 %) (for 14 days) PhysGen Biochemistry data blood potassium amount male 77.0 days-91.0 days 4 4.68 mmol/l 0.34 0.69 flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 38828 401
SS-Ghsrm3Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 2 146.5 mmol/l 1.5 2.12 flame atomic emission spectrometry 60899 527
SS-Cpt2m1Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 1 146.0 mmol/l flame atomic emission spectrometry 60905 527
SS-Klf4m3Mcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 8 139.5 mmol/l 1.35 3.82 flame atomic emission spectrometry 60904 527
SS/JrHsdMcwi serum sodium level controlled sodium content diet (1 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 17 143.24 mmol/l 0.86 3.53 flame atomic emission spectrometry 60907 527
FHH-Agtr1bm1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 14 4.59 mmol/l 0.16 0.6 flame atomic emission spectrometry 61297 527
F344-Plce1Tn(sb-T2/Bart3)2.146Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 6 4.23 mmol/l 0.4 0.97 flame atomic emission spectrometry 61299 527
FHH-Slc8a2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 12 5.43 mmol/l 0.55 1.89 flame atomic emission spectrometry 61302 527
FHH-Nr0b2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 10 4.76 mmol/l 0.24 0.75 flame atomic emission spectrometry 61305 527
FHH-Ccr2m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 4 4.78 mmol/l 0.19 0.39 flame atomic emission spectrometry 61310 527
FHH-F10m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 11 4.34 mmol/l 0.19 0.64 flame atomic emission spectrometry 61311 527
FHH-F10m2Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 16 5.74 mmol/l 0.42 1.69 flame atomic emission spectrometry 61316 527
F344-DccTn(sb-T2/Bart3)2.205Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 4 3.63 mmol/l 0.33 0.66 flame atomic emission spectrometry 61328 527
BN-Lcatm3Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 2 4.45 mmol/l 0.15 0.21 flame atomic emission spectrometry 61334 527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 7 3.97 mmol/l 0.26 0.69 flame atomic emission spectrometry 61355 527
BN/NHsdMcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 27 4.18 mmol/l 0.09 0.45 flame atomic emission spectrometry 61358 527
BN/NHsdMcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 43 4.8 mmol/l 0.09 0.62 flame atomic emission spectrometry 61357 527
F344-Stxbp5lTn(sb-T2/Bart3)2.202Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 4 4.0 mmol/l 0.22 0.43 flame atomic emission spectrometry 61360 527
FHH-Egln3m1Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount female 70.0 days-84.0 days 14 4.96 mmol/l 0.36 1.36 flame atomic emission spectrometry 61354 527
F344-Nrg1Tn(sb-T2/Bart3)2.183Mcwi serum potassium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood potassium amount male 70.0 days-84.0 days 5 4.2 mmol/l 0.21 0.46 flame atomic emission spectrometry 61359 527
FHH-Adipoqm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 9 140.44 mmol/l 1.76 5.27 flame atomic emission spectrometry 61772 527
FHH-Agtr1bm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 14 141.57 mmol/l 0.59 2.21 flame atomic emission spectrometry 61779 527
FHH-Lcatm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 15 139.0 mmol/l 0.51 1.96 flame atomic emission spectrometry 61783 527
FHH-Slc8a2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 12 139.42 mmol/l 0.82 2.84 flame atomic emission spectrometry 61784 527
F344-Elmod3Tn(sb-T2/Bart3)2.42Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 3 139.33 mmol/l 0.67 1.15 flame atomic emission spectrometry 61785 527
F344-Brinp3Tn(sb-T2/Bart3)2.189Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 3 145.67 mmol/l 1.45 2.52 flame atomic emission spectrometry 61794 527
FHH-Nr4a1m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 11 142.82 mmol/l 0.46 1.54 flame atomic emission spectrometry 61801 527
FHH-F10m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 10 138.0 mmol/l 1.01 3.2 flame atomic emission spectrometry 61808 527
FHH-F10m2Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 12 135.5 mmol/l 1.49 5.16 flame atomic emission spectrometry 61807 527
FHH-Nr4a1m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 11 140.09 mmol/l 0.61 2.02 flame atomic emission spectrometry 61809 527
FHH-Ghsrm1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 9 139.78 mmol/l 0.57 1.72 flame atomic emission spectrometry 61813 527
F344-Plcb3Tn(sb-T2/Bart3)2.69Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 3 140.67 mmol/l 1.2 2.08 flame atomic emission spectrometry 61820 527
FHH-Adipoqm3Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount female 70.0 days-84.0 days 6 136.17 mmol/l 1.76 4.31 flame atomic emission spectrometry 61824 527
FHH-Adipoqm3Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 5 135.8 mmol/l 1.93 4.32 flame atomic emission spectrometry 61825 527
FHH-Slc8a2m1Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 10 139.3 mmol/l 0.97 3.06 flame atomic emission spectrometry 61833 527
F344-Inpp4bTn(sb-T2/Bart3)2.143Mcwi serum sodium level controlled sodium content diet (4 %) (for 14 days) then fasting (for 16 hours) PhysGen Biochemistry data blood sodium amount male 70.0 days-84.0 days 7 143.14 mmol/l 2.04 5.4 flame atomic emission spectrometry 61837 527
SR/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 139.3 mmol/l 1.6 3.92 flame atomic emission spectrometry 0.0 102235 2682
SS/Hsd plasma sodium level controlled sodium content diet (0.4 %) (for 21 days) then intracerebroventricular cannula implantation then scrambled control oligodeoxynucleotide (4.17 ug/d) (for 21 days) then sham surgical control condition (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.3 mmol/l 1.3 3.18 flame atomic emission spectrometry 0.0 102253 2682
SS/Hsd plasma sodium level controlled sodium content diet (8 %) (for 21 days) then intracerebroventricular cannula implantation then Gnai2 antisense oligonucleotide (4.17 ug/d) (for 21 days) then surgical denervation (for 21 days) Wainford RD, et al., Hypertension. 2015 Jan;65(1):178-86. doi: 10.1161/HYPERTENSIONAHA.114.04463. Epub 2014 Oct 13. blood sodium amount male 91.0 days-119.0 days 6 140.4 mmol/l 1.1 2.69 flame atomic emission spectrometry 0.0 102256 2682