| F344/DuCrl |
percent change in ventilation |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
%change=VE during7-9 min hypercapnia/control during standard conditions |
286.63 |
% |
25.13 |
83.33 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15211 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
11 |
|
172.72 |
% |
11.52 |
38.21 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54177 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
167.6 |
% |
5.41 |
17.95 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54183 |
381 |
| F344/DuCrl |
absolute change in partial pressure of blood carbon dioxide |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood carbon dioxide amount |
male |
82.0 days-99.0 days |
9 |
|
-4.92 |
mmHg |
0.56 |
1.68 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17199 |
381 |
| F344/DuCrl |
tidal volume |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
0.32 |
ml |
0.01 |
0.05 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14011 |
381 |
| F344/DuCrl |
tidal volume |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
0.25 |
ml |
0.01 |
0.04 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14016 |
381 |
| F344/DuCrl |
respiration rate |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
11 |
|
195.69 |
breaths/min |
8.76 |
29.06 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17958 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
40.16 |
ml/min |
2.86 |
11.45 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18965 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
30.96 |
ml/min |
1.47 |
6.22 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18970 |
381 |
| F344/DuCrl |
tidal volume |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
0.46 |
ml |
0.02 |
0.08 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18521 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
163.78 |
% |
7.54 |
25.01 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54540 |
381 |
| F344/DuCrl |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
female |
77.0 days-91.0 days |
13 |
|
3.49 |
mg/kg |
0.6 |
2.15 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57771 |
526 |
| F344/DuCrl |
percent change in ventilation |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
%change=VE during 2-3 min hypercapnia/control during standard conditions |
293.22 |
% |
20.42 |
67.73 |
stop flow air displacement plethysmography |
0 |
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14406 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
110.67 |
% |
3.4 |
14.41 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54194 |
381 |
| F344/DuCrl |
respiration rate |
control condition |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
16 |
|
105.14 |
breaths/min |
4.12 |
16.48 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17325 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
32.82 |
ml/min |
1.38 |
5.86 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19724 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
86.67 |
ml/min |
3.85 |
12.77 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19588 |
381 |
| F344/DuCrl |
respiration rate |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
11 |
|
190.4 |
breaths/min |
6.9 |
22.88 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17963 |
381 |
| F344/DuCrl |
respiration rate |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
18 |
|
130.93 |
breaths/min |
5.56 |
23.59 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18214 |
381 |
| F344/DuCrl |
respiration rate |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
11 |
|
174.63 |
breaths/min |
4.42 |
14.67 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
20183 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
18 |
|
116.96 |
% |
4.5 |
19.08 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
53598 |
381 |
| F344/DuCrl |
absolute change in partial pressure of blood carbon dioxide |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood carbon dioxide amount |
male |
82.0 days-99.0 days |
7 |
|
-9.07 |
mmHg |
0.34 |
0.9 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17463 |
381 |
| F344/DuCrl |
minute ventilation |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
30.31 |
ml/min |
3.66 |
12.12 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15491 |
381 |
| F344/DuCrl |
absolute change in partial pressure of blood oxygen |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood oxygen amount |
female |
82.0 days-99.0 days |
9 |
|
7.56 |
mmHg |
5.05 |
15.15 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15517 |
381 |
| F344/DuCrl |
percent change in ventilation |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
%change=VE during 2-3 min hypercapnia/control during standard conditions |
316.87 |
% |
29.35 |
97.35 |
stop flow air displacement plethysmography |
0 |
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14401 |
381 |
| F344/DuCrl |
tidal volume |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
0.28 |
ml |
0.02 |
0.06 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14432 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
98.76 |
% |
1.9 |
7.62 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54199 |
381 |
| F344/DuCrl |
absolute change in partial pressure of blood carbon dioxide |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood carbon dioxide amount |
female |
82.0 days-99.0 days |
9 |
|
-7.01 |
mmHg |
0.56 |
1.67 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17204 |
381 |
| F344/DuCrl |
absolute change in partial pressure of blood oxygen |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood oxygen amount |
male |
82.0 days-99.0 days |
7 |
|
18.18 |
mmHg |
2.8 |
7.41 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14058 |
381 |
| F344/DuCrl |
absolute change in partial pressure of blood oxygen |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood oxygen amount |
female |
82.0 days-99.0 days |
3 |
|
13.35 |
mmHg |
4.38 |
7.58 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14061 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
40.7 |
ml/min |
1.66 |
6.65 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19719 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
71.58 |
ml/min |
3.62 |
12.0 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19593 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
78.77 |
ml/min |
3.23 |
10.72 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17582 |
381 |
| F344/DuCrl |
minute ventilation |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
30.33 |
ml/min |
1.04 |
4.16 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17905 |
381 |
| F344/DuCrl |
minute ventilation |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
24.46 |
ml/min |
1.29 |
5.47 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17910 |
381 |
| F344/DuCrl |
absolute change in blood pH |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood acidity-alkalinity balance trait |
female |
82.0 days-99.0 days |
3 |
|
-0.01 |
null |
0.03 |
0.05 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18816 |
381 |
| F344/DuCrl |
tidal volume |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
0.23 |
ml |
0.01 |
0.04 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19044 |
381 |
| F344/DuCrl |
respiration rate |
control condition |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
11 |
|
105.22 |
breaths/min |
7.94 |
26.35 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18158 |
381 |
| F344/DuCrl |
respiration rate |
control condition |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
11 |
|
112.81 |
breaths/min |
8.04 |
26.65 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18163 |
381 |
| F344/DuCrl |
respiration rate |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
16 |
|
129.3 |
breaths/min |
4.39 |
17.55 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18209 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
178.91 |
% |
3.98 |
13.21 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54535 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
109.0 |
% |
3.3 |
13.19 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
53614 |
381 |
| F344/DuCrl |
tidal volume |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
0.45 |
ml |
0.02 |
0.08 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15527 |
381 |
| F344/DuCrl |
absolute change in blood pH |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood acidity-alkalinity balance trait |
male |
82.0 days-99.0 days |
9 |
|
-0.01 |
null |
0.01 |
0.02 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15602 |
381 |
| F344/DuCrl |
percent change in ventilation |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
%change=VE during7-9 min hypercapnia/control during standard conditions |
288.9 |
% |
20.09 |
66.63 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15216 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
11 |
|
161.48 |
% |
8.84 |
29.32 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54188 |
381 |
| F344/DuCrl |
percent change in ventilation |
controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
%change=VE during7-9 min hypoxia/control during standard conditions |
133.03 |
% |
8.01 |
32.04 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17336 |
381 |
| F344/DuCrl |
respiration rate |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
16 |
|
142.68 |
breaths/min |
11.8 |
47.19 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17559 |
381 |
| F344/DuCrl |
minute ventilation |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
71.38 |
ml/min |
4.88 |
16.18 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17587 |
381 |
| F344/DuCrl |
absolute change in blood pH |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood acidity-alkalinity balance trait |
male |
82.0 days-99.0 days |
7 |
|
-0.03 |
null |
0.01 |
0.02 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18813 |
381 |
| F344/DuCrl |
tidal volume |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
0.29 |
ml |
0.01 |
0.05 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19039 |
381 |
| F344/DuCrl |
tidal volume |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
0.41 |
ml |
0.02 |
0.08 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
18526 |
381 |
| F344/DuCrl |
percent change in ventilation |
controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
%change=VE during 2-3 min hypoxia/control during standard conditions |
137.7 |
% |
6.98 |
29.6 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19308 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
18 |
|
124.71 |
% |
5.33 |
22.61 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54522 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
16 |
|
124.73 |
% |
4.78 |
19.12 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54527 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
16 |
|
137.28 |
% |
11.6 |
46.41 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
53603 |
381 |
| F344/DuCrl |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
female |
77.0 days-91.0 days |
12 |
|
2.98 |
mg/kg |
0.68 |
2.34 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
60114 |
526 |
| F344/DuCrl |
absolute change in partial pressure of blood carbon dioxide |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood carbon dioxide amount |
female |
82.0 days-99.0 days |
3 |
|
-11.72 |
mmHg |
0.8 |
1.38 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17466 |
381 |
| F344/DuCrl |
tidal volume |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
|
0.29 |
ml |
0.01 |
0.05 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
16035 |
381 |
| F344/DuCrl |
tidal volume |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
0.25 |
ml |
0.01 |
0.04 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
16040 |
381 |
| F344/DuCrl |
minute ventilation |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
26.17 |
ml/min |
2.81 |
9.32 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15496 |
381 |
| F344/DuCrl |
absolute change in partial pressure of blood oxygen |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood oxygen amount |
male |
82.0 days-99.0 days |
9 |
|
14.11 |
mmHg |
3.25 |
9.75 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15512 |
381 |
| F344/DuCrl |
tidal volume |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
0.38 |
ml |
0.02 |
0.07 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15532 |
381 |
| F344/DuCrl |
absolute change in blood pH |
resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
blood acidity-alkalinity balance trait |
female |
82.0 days-99.0 days |
9 |
|
-0.02 |
null |
0.01 |
0.03 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
15607 |
381 |
| F344/DuCrl |
tidal volume |
control condition |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
11 |
|
0.23 |
ml |
0.01 |
0.04 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
14437 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
11 |
|
162.0 |
% |
11.66 |
38.67 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
54172 |
381 |
| F344/DuCrl |
respiration rate |
control condition |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
18 |
|
107.06 |
breaths/min |
5.59 |
23.73 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17330 |
381 |
| F344/DuCrl |
percent change in ventilation |
controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
%change=VE during7-9 min hypoxia/control during standard conditions |
128.94 |
% |
5.94 |
25.2 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17341 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
11 |
|
175.77 |
% |
11.68 |
38.75 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
53852 |
381 |
| F344/DuCrl |
percent change in respiration rate |
controlled air carbon dioxide content (7 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
11 |
|
196.88 |
% |
17.41 |
57.75 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
53857 |
381 |
| F344/DuCrl |
respiration rate |
controlled air oxygen content (12 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
female |
82.0 days-99.0 days |
18 |
|
123.56 |
breaths/min |
6.1 |
25.9 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
17564 |
381 |
| F344/DuCrl |
percent change in ventilation |
controlled sodium content diet (0 %) then controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
male |
82.0 days-99.0 days |
16 |
%change=VE during 2-3 min hypoxia/control during standard conditions |
134.28 |
% |
3.49 |
13.97 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
19303 |
381 |
| F344/DuCrl |
respiration rate |
controlled air carbon dioxide content (7 %) (between 0.1 and 0.1 hours) |
PhysGen Respiratory data |
respiratory function trait |
male |
82.0 days-99.0 days |
11 |
|
173.67 |
breaths/min |
5.04 |
16.73 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
20178 |
381 |
| F344/DuCrl |
percent change in tidal volume |
controlled air oxygen content (12 %) (between 0 and 0.1 hours) |
PhysGen Respiratory data |
pulmonary ventilation trait |
female |
82.0 days-99.0 days |
18 |
|
110.44 |
% |
2.87 |
12.18 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
53609 |
381 |
| F344/DuCrl |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
controlled air oxygen content (12 %) (for 14 days) then methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
14 |
|
3.69 |
mg/kg |
0.79 |
2.96 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
57766 |
526 |
| F344/DuCrl |
dose of methacholine at which pulmonary conductance is half its pretreatment value |
methacholine (0-11.06 mg/kg) and drug dose time series (for 0.2 hours) |
PhysGen Lung data |
pulmonary ventilation trait |
male |
77.0 days-91.0 days |
7 |
|
2.3 |
mg/kg |
0.67 |
1.77 |
stop flow air displacement plethysmography |
|
|
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan |
60109 |
526 |