Phenominer Database Results (3191 results)

 
 
How to display a graph
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Formula Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
FHH-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 17 127.74 mmHg 4.23 17.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15064 381
SS-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 112.52 mmHg 3.33 9.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15080 381
SS-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 125.49 mmHg 5.13 14.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15078 381
SS-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 118.13 mmHg 7.12 27.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15093 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 124.92 mmHg 5.11 16.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15095 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 125.67 mmHg 8.51 22.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15100 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 138.04 mmHg 7.32 17.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15102 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 122.62 mmHg 4.76 10.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15103 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 126.2 mmHg 2.82 8.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15111 381
SS-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 122.82 mmHg 3.19 10.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15110 381
SS-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 142.04 mmHg 7.05 18.65 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15112 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 18 129.83 mmHg 3.33 14.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15113 381
SS-Chr XBN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 130.68 mmHg 8.72 21.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15119 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 136.44 mmHg 15.4 26.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15125 381
FHH-Chr 4BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 143.58 mmHg 30.04 42.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15124 381
SS-Chr 4BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 128.71 mmHg 3.46 10.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15130 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 14 122.79 mmHg 5.11 19.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15136 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 128.72 mmHg 4.12 14.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15134 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 143.07 mmHg 11.89 20.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15139 381
SS-Chr 2BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 127.43 mmHg 6.53 22.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15140 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 20.71 mmHg 3.11 8.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15147 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 425.88 beats/min 7.92 11.2 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15195 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 126.99 mmHg 3.33 10.55 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15199 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 126.83 mmHg 3.13 8.27 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15205 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 24.62 mmHg 9.29 20.76 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15536 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 14.18 mmHg 1.52 4.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15535 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 11.56 mmHg 2.95 7.22 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15539 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 9.55 mmHg 3.54 7.91 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15543 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 13.06 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15542 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 128.32 mmHg 7.56 22.67 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15548 381
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 131.36 mmHg 1.4 3.71 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15550 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 107.08 mmHg 1.69 3.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15554 381
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 151.69 mmHg 3.57 8.74 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15557 381
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 381.66 beats/min 15.84 41.9 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15588 381
FHH/EurMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 318.89 beats/min 20.99 36.36 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15593 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 47.76 mmHg vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15757 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 17.81 mmHg vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15758 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 16.37 mmHg 3.8 6.59 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15759 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 7.27 mmHg 10.91 18.9 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15763 381
WKY/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 505.34 beats/min 9.87 31.2 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15789 381
F344/DuCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 112.28 mmHg 2.36 8.5 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15796 381
SS-Chr 6BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 441.34 beats/min 6.17 20.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15906 381
SS-Chr 14BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 399.16 beats/min 8.12 24.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15909 381
SS-Chr 9BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 457.61 beats/min 11.08 35.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15910 381
FHH-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 442.3 beats/min 3.26 6.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15915 381
SS-Chr 10BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 463.34 beats/min 4.29 11.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15913 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 438.2 beats/min 10.21 28.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15930 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 452.12 beats/min 11.47 34.4 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15931 381
SS-Chr 15BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 382.79 beats/min 33.08 46.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15934 381
FHH-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 423.87 beats/min 14.54 29.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15938 381
SS-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 415.36 beats/min 15.12 42.77 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15338 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 105.83 mmHg 7.4 14.81 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14414 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 121.93 mmHg 6.18 10.71 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14657 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 104.25 mmHg 4.97 7.03 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14654 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 109.62 mmHg 6.18 16.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14663 381
FHH/EurMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 125.82 mmHg 3.56 10.69 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14667 381
SS-Chr 17BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 368.79 beats/min 9.54 19.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14684 381
FHH-Chr 17BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 351.92 beats/min 14.8 36.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14688 381
SS-Chr 5BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 413.38 beats/min 35.54 50.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14691 381
GH/OmrMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 411.24 beats/min 20.29 40.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14693 381
FHH-Chr 8BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 361.03 beats/min 16.16 42.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14697 381
SS-Chr 7BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 421.79 beats/min 8.13 22.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14694 381
SS-Chr 13BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 419.34 beats/min 15.43 40.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14712 381
FHH-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 742.73 beats/min 162.02 362.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15959 381
FHH-Chr 1BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 482.19 beats/min 14.03 37.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15974 381
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 2.96 beats/min 11.93 26.67 vascular fluid filled catheter 51680 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -67.69 beats/min 13.34 40.01 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51689 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -27.52 beats/min 20.21 45.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51690 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -12.33 beats/min 17.47 52.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51696 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -73.43 beats/min 9.14 35.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51705 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -13.51 beats/min 6.01 15.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51710 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -32.18 beats/min 19.16 38.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51709 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -96.57 beats/min 21.74 57.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51715 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 -24.39 beats/min 8.55 34.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51718 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -21.04 beats/min 12.68 28.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51725 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -7.96 beats/min 11.66 45.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51727 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 101.2 mmHg 3.26 7.28 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51733 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 13.75 mmHg 2.88 6.44 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51737 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 14.06 mmHg 2.07 2.92 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51738 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 129.64 mmHg 6.29 12.58 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51742 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 36.87 mmHg 3.95 11.85 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51767 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 27.49 mmHg 2.28 9.69 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51769 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 35.87 mmHg 2.98 10.33 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51772 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 16.69 mmHg 3.46 10.39 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51777 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 16.08 mmHg 3.41 9.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51779 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 7.38 mmHg 3.34 10.01 vascular fluid filled catheter 51786 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 22.76 beats/min 15.34 34.3 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51792 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 21.68 mmHg 7.01 17.16 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51814 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 10 130.93 mmHg 4.07 12.88 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51826 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 3 97.79 mmHg 9.11 15.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51831 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 117.77 mmHg 2.86 7.56 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51828 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -8.33 beats/min 29.02 82.09 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51856 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 13.26 mmHg 1.18 2.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51865 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 16.83 mmHg 2.71 7.17 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51870 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 14 -14.62 beats/min 14.72 55.08 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51876 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 105.66 mmHg 2.34 6.2 vascular fluid filled catheter 51878 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 103.93 mmHg 3.0 7.95 vascular fluid filled catheter 51879 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 102.52 mmHg 3.77 8.44 vascular fluid filled catheter 51907 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 119.18 mmHg 4.08 10.0 vascular fluid filled catheter 51909 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 29.83 mmHg 4.13 8.26 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51912 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 -26.7 beats/min 9.39 18.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51928 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 7.17 beats/min 11.83 33.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51927 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -46.2 beats/min 14.43 38.19 vascular fluid filled catheter 51940 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 12.69 beats/min 16.61 43.95 vascular fluid filled catheter 51938 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 16.58 mmHg 2.37 7.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51961 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 19.47 mmHg 4.39 10.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51972 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 2 191.9 beats/min 134.3 189.93 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51983 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -15.76 beats/min 11.84 26.47 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51982 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 0.66 mmHg 4.76 10.64 vascular fluid filled catheter 51993 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 137.89 mmHg 7.62 15.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52007 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -0.9 mmHg 3.53 9.35 vascular fluid filled catheter 52026 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -6.25 beats/min 7.6 21.49 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52059 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -11.5 beats/min 9.79 29.36 vascular fluid filled catheter 52064 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -23.93 beats/min 10.03 22.42 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 52068 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -31.31 beats/min 14.7 38.9 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 52069 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -14.34 beats/min 12.39 32.79 vascular fluid filled catheter 52075 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -73.2 beats/min 18.38 55.13 vascular fluid filled catheter 52078 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 126.85 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52083 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 136.28 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52086 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 104.93 mmHg 2.81 7.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52091 481
SS-Chr 14BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 8 176.19 mmHg 8.36 23.66 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52835 482
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 8 160.18 mmHg 5.39 15.25 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52836 482
SS-Chr 17BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 184.37 mmHg 9.44 28.33 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52839 482
SS-Chr 17BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 6 171.61 mmHg 11.27 27.61 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52841 482
SS-Chr 5BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 130.42 mmHg 2.59 6.85 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52844 482
SS-Chr 7BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 10 146.46 mmHg 2.72 8.6 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52840 482
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 8 135.4 mmHg 3.37 9.54 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52846 482
SS-Chr 3BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 175.29 mmHg 9.17 27.52 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52849 482
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 8 134.57 mmHg 2.52 7.13 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52858 482
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 59 176.81 mmHg 2.61 20.06 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52859 482
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 18 112.49 mmHg 2.77 11.74 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52875 482
LE/BluGill mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 112.29 mmHg 0.72 1.91 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52242 482
FHH-Chr 15BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 383.93 beats/min 7.94 23.83 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52485 482
FHH-Chr 13BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 10 416.71 beats/min 4.29 13.58 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52500 482
FHH-Chr 12BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 12 431.99 beats/min 6.5 22.51 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52503 482
FHH-Chr 18BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 8 415.13 beats/min 8.11 22.93 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52504 482
FHH-Chr 16BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 7 448.63 beats/min 9.21 24.37 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52512 482
FHH-Chr 1BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 445.83 beats/min 7.54 22.62 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52513 482
FHH-Chr 9BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 4 437.66 beats/min 5.03 10.06 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52521 482
FHH-Chr 7BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 427.55 beats/min 5.81 17.42 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52522 482
FHH-Chr 9BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 4 409.54 beats/min 10.2 20.4 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52527 482
FHH-Chr XBN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 5 452.27 beats/min 6.2 13.85 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52526 482
FHH-Chr 15BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 160.32 mmHg 5.98 17.94 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52532 482
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 15 165.97 mmHg 7.47 28.91 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52534 482
FHH-Chr 8BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 8 141.23 mmHg 4.54 12.85 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52533 482
FHH-Chr 14BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 6 156.03 mmHg 5.11 12.52 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52539 482
FHH-Chr 5BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 174.07 mmHg 8.96 23.69 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52543 482
FHH-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 182.05 mmHg 4.28 12.83 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52548 482
FHH-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 7 166.54 mmHg 13.12 34.7 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52559 482
FHH-Chr 4BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 5 196.5 mmHg 2.44 5.46 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52561 482
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 12 173.37 mmHg 6.04 20.93 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52563 482
FHH-Chr XBN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 6 186.45 mmHg 7.42 18.17 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52566 482
FHH-Chr 10BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 5 186.54 mmHg 7.17 16.04 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52570 482
SS-Chr 14BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 416.82 beats/min 7.99 23.98 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52633 482
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 410.8 beats/min 6.42 19.25 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52647 482
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 8 421.13 beats/min 9.77 27.62 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52648 482
SS-Chr YBN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 15 387.26 beats/min 8.89 34.45 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52659 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 20 381.98 beats/min 5.84 26.1 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52674 482
BN/NHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 363.56 beats/min 5.85 17.55 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52676 482
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 356.76 beats/min 13.66 40.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50528 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 11.58 mmHg 5.14 10.28 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50544 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 100.45 mmHg 3.23 8.55 vascular fluid filled catheter 50547 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 9.34 beats/min 8.51 25.54 vascular fluid filled catheter 50552 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -53.6 beats/min 20.05 49.12 vascular fluid filled catheter 50553 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 -24.45 beats/min 31.16 62.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50590 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -9.39 beats/min 43.01 96.17 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50594 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -58.76 beats/min 39.1 103.44 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50596 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -52.77 beats/min 23.98 67.84 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50597 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 3.22 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50604 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -1.7 mmHg 1.59 4.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50608 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -26.25 beats/min 11.9 23.81 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50623 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 3 -15.69 mmHg 7.96 13.79 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50629 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -4.07 mmHg 2.8 6.86 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50628 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 -17.3 mmHg 2.31 6.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50633 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 3 -2.03 mmHg 7.23 12.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50637 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -23.04 mmHg 2.62 6.92 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50634 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 153.09 mmHg 2.46 6.96 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50645 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 163.86 mmHg 4.26 12.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50647 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 140.95 mmHg 2.98 8.43 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50648 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 29.46 mmHg 1.58 4.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50655 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 39.84 mmHg 3.0 11.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50654 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 46.25 mmHg 3.11 7.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50660 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 38.74 mmHg 4.66 12.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50659 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 35.01 mmHg 2.36 9.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50662 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 398.3 beats/min 7.53 18.44 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50666 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 419.88 beats/min 29.05 82.16 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50671 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 387.4 beats/min 19.95 52.79 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50670 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 115.54 mmHg 2.1 4.7 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50676 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 83.6 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50679 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 13 17.49 beats/min 12.18 43.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50680 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 20.24 beats/min 10.4 25.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50685 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -5.23 beats/min 21.31 56.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50686 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 4.59 mmHg 1.15 2.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50694 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 10.43 mmHg 7.64 15.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50700 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 391.94 beats/min 27.41 67.15 vascular fluid filled catheter 50711 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -60.45 beats/min 16.96 50.87 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50716 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 28.48 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50720 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -5.86 beats/min 17.62 46.62 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50724 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -12.7 beats/min 20.48 40.96 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50727 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -37.71 beats/min 15.71 47.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50726 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -25.21 beats/min 19.43 54.97 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50728 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 44.13 beats/min 17.99 53.96 vascular fluid filled catheter 50731 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 173.36 mmHg 5.88 16.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50739 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 33.62 mmHg 2.46 7.39 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50760 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 34.94 mmHg 9.38 18.76 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50759 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 2.9 mmHg 2.1 5.56 vascular fluid filled catheter 50771 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 2.19 mmHg 1.66 4.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50772 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 4.89 mmHg 4.16 11.0 vascular fluid filled catheter 50769 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 5.95 mmHg 2.39 9.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50774 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 4.84 mmHg 2.48 8.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50779 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 3 49.33 mmHg 4.56 7.91 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50785 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 34.46 mmHg 0.85 1.2 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50787 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 -9.46 mmHg 3.26 6.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50813 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 397.17 beats/min 12.82 44.43 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50814 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 -0.7 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50819 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 16.8 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50823 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -34.6 beats/min 31.31 70.02 vascular fluid filled catheter 50833 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 4.72 mmHg 4.89 6.92 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50843 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -31.59 beats/min 11.86 31.37 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50848 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 -1.05 mmHg 1.42 5.31 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50849 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 384.12 beats/min 4.27 11.3 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50853 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 7.74 mmHg 2.21 5.42 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50858 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -42.8 beats/min 16.6 40.66 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50866 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 429.29 beats/min 17.71 66.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50887 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 380.26 beats/min 6.27 15.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50886 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 3 43.55 mmHg 0.46 0.79 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50898 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 34.4 mmHg 3.93 8.78 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50902 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 3 15.12 beats/min 28.47 49.3 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50908 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 4.25 mmHg 0.13 0.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50914 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 14 420.32 beats/min 6.65 24.88 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50924 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 2.88 mmHg 1.84 5.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50926 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 1.42 mmHg 2.41 7.24 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50925 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 3.68 mmHg 1.76 3.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50928 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 1.04 mmHg 1.37 4.76 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50932 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 122.29 mmHg 2.81 6.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50938 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 16 139.76 mmHg 3.93 15.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50939 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 131.22 mmHg 4.62 11.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50942 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 394.94 beats/min 8.93 33.43 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50956 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 7.36 mmHg 1.31 3.45 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50959 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 36.57 mmHg 4.18 9.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50960 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 18.73 mmHg 1.8 5.4 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50963 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 29.71 mmHg 9.04 18.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50966 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 36.39 mmHg 2.2 8.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50965 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 41.32 mmHg 5.66 13.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50971 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 4.14 mmHg 2.16 4.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50992 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 -2.59 mmHg 3.89 7.79 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50991 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 -0.36 mmHg 1.59 5.52 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51000 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 14 -2.46 mmHg 2.3 8.59 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51001 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 1.24 mmHg 2.67 7.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51028 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 20 21.45 mmHg 1.58 7.06 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51032 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 13.07 mmHg 1.59 4.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51031 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -47.6 beats/min 15.76 47.28 vascular fluid filled catheter 51040 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 14 1.22 mmHg 1.8 6.74 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51039 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -49.8 beats/min 33.0 46.67 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51072 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 117.34 mmHg 1.33 3.99 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51077 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 113.23 mmHg 1.95 5.15 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51076 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 -1.22 mmHg 1.22 2.99 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51080 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 1.42 mmHg 1.42 2.0 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51083 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 3.43 beats/min 11.16 29.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51086 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 0.56 beats/min 2.95 8.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51094 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -2.86 beats/min 5.12 13.54 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51095 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 8.89 mmHg 2.26 9.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51101 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 16.96 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51103 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 0.45 mmHg 3.08 9.25 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51109 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 459.04 beats/min 15.7 35.11 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51115 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 407.56 beats/min 12.77 38.31 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51112 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 337.8 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51118 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 405.69 beats/min 11.75 49.86 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51114 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 431.06 beats/min 10.72 30.33 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51124 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 15.03 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51128 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 -1.56 mmHg 2.17 8.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51132 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 129.62 mmHg 2.92 8.27 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51150 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 148.3 mmHg 5.49 19.02 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51147 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 139.16 mmHg 4.78 13.51 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51149 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 114.16 mmHg 3.59 7.17 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51151 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -11.67 beats/min 9.62 37.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51155 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -31.18 beats/min 16.53 40.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51157 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -14.82 beats/min 11.3 33.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51156 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -16.07 beats/min 16.66 49.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51162 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -3.93 beats/min 14.49 38.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51165 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 12.46 mmHg 3.39 7.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51183 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 29.32 mmHg 4.58 17.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51185 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -27.08 beats/min 15.11 33.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51217 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -12.27 beats/min 14.94 44.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51220 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -96.0 beats/min 16.27 39.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51221 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -27.71 beats/min 7.08 18.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51224 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -58.2 beats/min 16.54 49.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51226 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 0.4 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51232 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -22.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51235 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -22.66 beats/min 17.34 45.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51239 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -1.39 beats/min 7.41 20.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51240 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 3 407.56 beats/min 2.82 4.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51247 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 10 407.56 beats/min 6.03 19.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51250 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 432.84 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51254 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 0.36 beats/min 7.52 16.81 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51262 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 5.85 beats/min 9.6 28.81 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51263 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 381.9 beats/min 3.85 11.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51286 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 121.87 mmHg 1.99 7.45 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51300 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 111.52 mmHg 1.62 4.3 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51301 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -41.07 beats/min 25.09 61.47 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51304 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -74.2 beats/min 17.8 25.17 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51305 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 2 50.5 beats/min 43.3 61.24 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51308 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 3 107.87 mmHg 1.27 2.21 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51327 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 108.35 mmHg 1.6 4.22 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51328 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 22.76 beats/min 22.93 60.67 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51332 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 17.05 mmHg 3.97 10.51 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51337 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 10.7 mmHg 1.87 5.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51345 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -60.48 beats/min 20.94 51.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51352 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -7.68 beats/min 19.7 39.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51354 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 -15.3 beats/min 12.74 54.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51368 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 -17.82 beats/min 8.09 28.03 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51371 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -14.77 beats/min 11.54 39.96 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51373 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -37.73 beats/min 10.68 26.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51375 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 10.88 beats/min 4.58 12.97 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51378 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 423.79 beats/min 7.38 16.5 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51382 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 20.86 beats/min 10.81 37.45 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51400 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 41.75 mmHg 2.35 7.05 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51426 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 39.47 mmHg 5.6 11.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51431 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 384.83 beats/min 13.09 29.27 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51482 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 20 9.53 mmHg 1.49 6.66 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51479 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 402.6 beats/min 5.87 13.12 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51484 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 20.44 mmHg 5.29 11.82 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51490 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 412.5 beats/min 7.03 19.89 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51487 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -37.54 beats/min 13.84 41.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51501 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 -43.12 beats/min 5.21 21.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51503 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 -41.61 beats/min 8.9 28.13 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51507 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -42.14 beats/min 19.17 54.23 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51511 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -56.79 beats/min 10.91 42.25 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51574 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 408.4 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51579 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 394.2 beats/min 7.4 18.12 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51578 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 424.37 beats/min 8.48 18.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51580 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 361.82 beats/min 5.01 14.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51585 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 375.38 beats/min 9.95 28.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51584 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 10 401.83 beats/min 4.13 13.07 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51583 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 382.78 beats/min 3.08 9.73 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51586 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 5.34 mmHg 1.79 3.99 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51590 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 4.26 mmHg 2.27 7.18 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51595 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 -3.51 mmHg 2.57 5.13 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51601 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -4.71 mmHg 2.19 6.57 vascular fluid filled catheter 51624 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 131.21 mmHg 4.02 8.99 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51629 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 144.43 mmHg 4.76 16.47 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51633 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 129.66 mmHg 2.23 5.45 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51635 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 30.91 mmHg 4.23 11.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51665 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 20 405.19 beats/min 8.56 38.28 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51677 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 387.81 beats/min 8.14 31.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50323 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 20 124.48 mmHg 1.9 8.48 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50333 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 114.94 mmHg 1.51 5.86 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50334 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -20.24 beats/min 14.12 31.57 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50337 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -57.41 beats/min 0.99 1.4 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50338 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -51.54 beats/min 9.58 23.46 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50343 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -21.75 beats/min 16.71 64.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50355 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -12.88 beats/min 7.63 18.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50364 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 15.56 mmHg 2.72 10.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50367 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 -0.61 mmHg 2.07 4.64 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50432 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 -2.02 mmHg 7.38 14.75 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50431 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 392.07 beats/min 16.4 40.18 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50444 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 3 356.33 beats/min 4.7 8.14 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50445 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 2 272.8 beats/min 82.0 115.97 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50450 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 389.0 beats/min 7.78 30.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50472 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 400.57 beats/min 8.14 21.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50477 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 358.13 beats/min 16.04 39.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50481 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 392.83 beats/min 17.75 46.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50482 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 385.51 beats/min 15.45 46.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50479 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 366.96 beats/min 10.76 41.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50480 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 37.32 beats/min 16.66 57.7 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50507 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -0.13 beats/min 12.28 42.54 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50509 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 23.0 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50508 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 43.14 beats/min 20.88 55.24 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50510 481
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 51 370.19 beats/min 5.38 38.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14723 381
SS-Chr 12BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 414.25 beats/min 14.6 29.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14738 381
BN/NHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 202.48 beats/min 19.79 55.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14739 381
SS.BN-(D13Rat7-D13Rat60)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 148.0 mmHg 3.7 12.82 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5395 15
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 177.0 mmHg 5.0 17.32 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5405 15
SS-Chr 9BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 heart rate during walking-heart rate during rest 73.15 beats/min 8.98 26.95 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13390 381
SS-Chr 6BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 heart rate during walking-heart rate during rest 88.91 beats/min 5.96 17.88 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13391 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 heart rate during walking-heart rate during rest 58.52 beats/min 6.1 8.62 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13393 381
SS-Chr 13BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 heart rate during walking-heart rate during rest 59.04 beats/min 10.62 28.1 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13394 381
SS-Chr 20BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 heart rate during walking-heart rate during rest 91.98 beats/min 11.42 32.3 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13392 381
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 heart rate during walking-heart rate during rest 40.83 beats/min 26.27 58.74 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13400 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 heart rate during walking-heart rate during rest 50.91 beats/min 17.59 43.08 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13403 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 heart rate during walking-heart rate during rest 72.73 beats/min 16.0 45.27 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13402 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 heart rate during walking-heart rate during rest 70.28 beats/min 11.8 37.32 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13409 381
SS-Chr 2BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 heart rate during walking-heart rate during rest 92.25 beats/min 11.0 33.01 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13413 381
LEW/Crl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 14 109.61 mmHg 2.0 7.47 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13450 381
WKY/NCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 117.67 mmHg 6.65 21.03 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13448 381
Crl:CD(SD) mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 128.25 mmHg 4.46 12.62 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13453 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 125.46 mmHg 2.74 8.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13465 381
SS-Chr 6BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 114.7 mmHg 3.65 11.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13468 381
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 114.25 mmHg 2.73 8.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13467 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 116.56 mmHg 6.07 12.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13472 381
SS-Chr 10BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 113.77 mmHg 3.3 8.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13470 381
SS-Chr 3BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 129.67 mmHg 6.23 13.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13490 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 110.66 mmHg 5.36 10.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13495 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 123.41 mmHg 4.68 12.38 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13494 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 119.71 mmHg 3.16 7.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13503 381
SS-Chr 11BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 130.11 mmHg 6.01 14.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13504 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 47.44 mmHg 31.78 71.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13516 381
SS-Chr 4BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 126.58 mmHg 3.0 7.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13521 381
SS-Chr 19BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 114.47 mmHg 12.96 22.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13518 381
SS-Chr 12BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 109.17 mmHg 7.13 10.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13519 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 122.67 mmHg 8.52 12.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13522 381
SS-Chr 12BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 106.81 mmHg 14.55 29.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13525 381
Hsd:SD mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 113.27 mmHg 6.46 20.44 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 13663 381
Hsd:SD mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 113.71 mmHg 3.83 15.33 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 13664 381
FHH-Chr 6BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 112.34 mmHg 53.92 76.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14305 381
SS-Chr 14BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 124.12 mmHg 2.89 8.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14311 381
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 117.91 mmHg 4.08 13.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14312 381
FHH-Chr 12BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 119.18 mmHg 4.58 15.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14314 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 107.75 mmHg 13.03 26.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14317 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 128.35 mmHg 6.12 17.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14324 381
SHR/NCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 147.31 mmHg 5.31 20.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14327 381
SS-Chr 5BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 103.61 mmHg 24.88 35.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14328 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 116.74 mmHg 5.82 16.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14330 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 112.88 mmHg 3.68 12.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14334 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 130.8 mmHg 5.3 16.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14332 381
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 137.78 mmHg 11.93 23.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14335 381
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 108.1 mmHg 6.38 20.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14345 381
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 116.93 mmHg 3.92 13.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14348 381
SS-Chr YBN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 18 121.57 mmHg 3.51 14.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14353 381
SS-Chr 4BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 131.58 mmHg 5.21 13.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14360 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 61.26 mmHg 34.35 84.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14363 381
SS-Chr 19BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 119.41 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14369 381
SS-Chr 12BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 116.75 mmHg 11.49 22.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14373 381
SS-Chr 2BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 121.23 mmHg 6.91 21.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14371 381
SS-Chr XBN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 138.26 mmHg 9.24 24.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14376 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 108.81 mmHg 6.39 14.28 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13764 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 122.92 mmHg 3.54 11.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13765 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 528.08 beats/min 5.36 15.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13784 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 497.47 beats/min 13.82 33.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13787 381
SS-Chr 6BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 516.46 beats/min 5.61 22.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13788 381
SS-Chr 13BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 488.0 beats/min 17.43 52.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13792 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 484.14 beats/min 9.02 32.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13799 381
SS-Chr 7BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 471.1 beats/min 13.26 35.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13804 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 503.88 beats/min 14.61 43.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13808 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 483.74 beats/min 10.36 32.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13810 381
Hsd:SD mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 106.91 mmHg 4.57 14.44 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 13825 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 519.82 beats/min 3.7 6.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13829 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 503.63 beats/min 19.37 47.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13833 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 484.58 beats/min 18.21 40.72 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13830 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 517.71 beats/min 27.96 48.43 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13832 381
LEW/Crl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 105.59 mmHg 2.75 11.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13877 381
Crl:CD(SD) mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 119.4 mmHg 7.03 18.6 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13878 381
FHH/EurMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 121.35 mmHg 1.4 3.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13888 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 521.35 beats/min 10.07 22.51 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14062 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 517.39 beats/min 7.14 20.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14065 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 514.24 beats/min 11.72 31.01 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14069 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 525.71 beats/min 7.93 17.74 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14071 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 475.49 beats/min 11.17 19.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14070 381
WKY/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 131.05 beats/min 11.64 26.03 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14109 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 26.99 beats/min 41.14 71.26 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14107 381
Crl:CD(SD) absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 83.32 beats/min 9.37 22.94 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14112 381
F344/DuCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 66.41 beats/min 11.36 30.04 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14113 381
LE/BluGill absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 89.97 beats/min 7.65 22.96 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14119 381
DRY mean arterial blood pressure control condition Innes BA, et al., Hypertension 1998 Mar;31(3):741-6 arterial blood pressure trait male 140.0 days 35 continuous mean 132.0 mmHg 1.18 7.0 vascular fluid filled catheter carotid artery 30 minutes 11668 113
SHR/N mean arterial blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait female 84.0 days 16 141.0 mmHg 8.0 32.0 vascular fluid filled catheter right carotid 13053 327
WKY/N mean arterial blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait male 84.0 days 15 110.0 mmHg 8.0 30.98 vascular fluid filled catheter right carotid 13061 327
WKY/N mean arterial blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait female 84.0 days 22 117.0 mmHg 5.0 23.45 vascular fluid filled catheter right carotid 13069 327
SS.LEW-(D5Rat130-D5Rat72)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 21 and 25 days) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. arterial blood pressure trait male 82.0 days-86.0 days 32 serial mean 190.0 mmHg vascular fluid filled catheter femoral artery 345600 connected to solid-state transducer (Argon Medical Technologies, Athens, TX) 5 hr recording session - 1 min. averages, averaged over 4 days 12614 272
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 102.4 mmHg 5.22 11.68 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19712 381
SS-Chr 5BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 107.29 mmHg 7.28 10.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19859 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 117.74 mmHg 5.09 14.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19864 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 152.85 mmHg 5.13 10.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19861 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 115.68 mmHg 3.64 10.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19868 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 111.25 mmHg 15.08 33.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19873 381
SS-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 128.65 mmHg 3.99 9.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19885 381
SS-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 114.63 mmHg 2.94 8.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19887 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 50 122.9 mmHg 2.03 14.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19891 381
SS-Chr XBN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 105.78 mmHg 6.13 10.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19892 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 116.27 mmHg 6.93 19.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19893 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 119.38 mmHg 3.99 12.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19896 381
LEW/Crl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 27.86 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20716 381
SS-Chr 6BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 16.27 mmHg 2.75 10.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20717 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 9.95 mmHg 3.06 11.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20720 381
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 10.33 mmHg 4.12 10.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20724 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 12.99 mmHg 0.98 2.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20735 381
SS-Chr 2BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 13.51 mmHg 1.67 5.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20745 381
Hsd:SD mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 113.37 mmHg 3.55 9.39 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 20845 381
SS-Chr 9BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 419.61 beats/min 11.2 31.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20899 381
SS-Chr 14BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 395.63 beats/min 4.54 13.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20902 381
SS-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 366.24 beats/min 16.81 33.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20912 381
FHH-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 423.0 beats/min 15.29 43.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20915 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 402.39 beats/min 3.16 7.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20916 381
FHH-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 385.43 beats/min 11.73 35.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20920 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 414.06 beats/min 6.01 19.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20930 381
FHH-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 395.52 beats/min 14.04 42.12 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20935 381
SS-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 430.23 beats/min 12.19 38.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20936 381
FHH-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 373.53 beats/min 10.07 28.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20937 381
SS-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 438.51 beats/min 17.08 48.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20943 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 62 413.02 beats/min 4.88 38.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20947 381
SS-Chr XBN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 369.83 beats/min 24.86 60.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20948 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 451.63 beats/min 7.56 25.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20952 381
SS-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 465.46 beats/min 30.76 68.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20957 381
FHH-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 379.42 beats/min 20.52 54.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20958 381
SS-Chr 4BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 433.25 beats/min 12.78 40.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20959 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 419.73 beats/min 8.86 28.02 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20971 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 415.78 beats/min 9.77 21.86 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20975 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 106.53 beats/min vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20991 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 44.0 beats/min 18.08 31.32 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20996 381
SS-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 103.15 mmHg 1.51 2.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19900 381
SS-Chr 2BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 129.71 mmHg 6.29 17.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19904 381
SS-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 121.12 mmHg 3.41 6.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19906 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 112.48 mmHg 3.95 11.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19907 381
SS-Chr 2BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 124.86 mmHg 3.65 10.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19911 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 481.67 beats/min 28.15 48.76 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19933 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 519.32 beats/min 7.99 17.86 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19939 381
SS-Chr 20BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 519.94 beats/min 16.0 45.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19952 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 541.74 beats/min 8.25 23.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19953 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 22 524.94 beats/min 8.14 38.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19954 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 532.8 beats/min 11.19 22.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19957 381
SS-Chr 9BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 553.45 beats/min 22.29 38.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19965 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 526.81 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19964 381
SS-Chr 20BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 13 114.91 mmHg 3.65 13.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20035 381
LEW/Crl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 86.86 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20038 381
SS-Chr 6BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 14 115.88 mmHg 1.48 5.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20045 381
SS-Chr 20BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 106.31 mmHg 4.59 13.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20046 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 134.87 mmHg 3.8 5.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20047 381
SHR/NCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 145.43 mmHg 5.96 16.86 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20057 381
LEW/Crl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 17 19.89 mmHg 2.44 10.07 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20104 381
LE/BluGill absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 10.15 mmHg 1.56 4.68 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20112 381
Crl:CD(SD) mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 125.48 mmHg 5.8 14.2 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20132 381
Hsd:SD mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 117.54 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20130 381
F344/DuCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 123.3 mmHg 4.67 12.35 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20133 381
WKY/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 116.05 mmHg 5.37 16.99 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20137 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 101.71 mmHg 1.74 3.01 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19521 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 136.24 mmHg 5.73 16.22 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19523 381
Crl:CD(SD) heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 386.27 beats/min 10.38 29.36 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19540 381
LEW/Crl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 395.59 beats/min 9.93 39.72 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19539 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 396.58 beats/min 15.33 30.67 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17662 381
GH/OmrMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 456.22 beats/min 3.88 6.71 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17665 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 406.9 beats/min 9.15 20.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17666 381
SS-Chr 6BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 440.35 beats/min 7.51 30.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17731 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 397.51 beats/min 6.68 18.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17733 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 432.59 beats/min 5.92 23.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17734 381
SS-Chr 13BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 387.5 beats/min 16.73 44.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17740 381
FHH-Chr 1BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 403.98 beats/min 13.88 39.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17744 381
GH/OmrMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 407.09 beats/min 12.96 28.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17750 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 401.44 beats/min 7.05 25.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17755 381
BN/NHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 17 365.45 beats/min 5.26 21.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17756 381
SS-Chr 20BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 124.38 mmHg 6.98 19.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17761 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 129.77 mmHg 5.05 13.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17765 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 126.26 mmHg 7.62 15.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17760 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 117.69 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17767 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 132.23 mmHg 3.83 6.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17770 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 136.01 mmHg 0.64 1.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17777 381
LEW/Crl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 14 282.47 beats/min 10.35 38.71 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18080 381
LEW/Crl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 274.56 beats/min 10.65 35.32 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18085 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 430.66 beats/min 12.88 38.63 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18110 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 96.82 beats/min 16.87 37.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18353 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 142.49 beats/min 13.52 33.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18358 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 62.93 beats/min 23.36 40.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18367 381
Hsd:SD heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 415.03 beats/min 10.24 14.47 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18385 381
F344/DuCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 419.5 beats/min 7.63 21.59 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18388 381
LE/BluGill heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 428.73 beats/min 6.67 17.66 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18390 381
Hsd:SD heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 467.01 beats/min 10.73 37.15 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 18749 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 466.65 beats/min 11.1 31.39 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18755 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 431.15 beats/min 29.19 71.49 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18759 381
LEW/Crl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 18 96.21 mmHg 1.97 8.35 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18780 381
LE/BluGill mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 97.16 mmHg 1.56 4.94 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18779 381
Hsd:SD heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 466.17 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18793 381
Hsd:SD mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 106.11 mmHg 5.77 15.27 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 18925 381
SS-Chr 9BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 124.13 mmHg 1.97 5.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18933 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 38 130.32 mmHg 2.26 13.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18944 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 155.16 mmHg 7.05 17.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18950 381
SS-Chr 2BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 128.91 mmHg 3.38 11.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18955 381
SS-Chr 7BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 131.94 mmHg 5.2 17.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18953 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 120.55 mmHg 4.27 15.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18957 381
SS-Chr 2BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 141.27 mmHg 4.76 14.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18960 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 129.06 mmHg 3.94 13.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18959 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 126.03 mmHg 4.32 6.1 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19006 381
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 296.33 beats/min 106.07 150.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17478 381
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 453.24 beats/min 20.85 69.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17485 381
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 399.96 beats/min 16.39 49.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17491 381
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 401.26 beats/min 38.1 76.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17490 381
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 403.95 beats/min 35.32 70.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17496 381
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 443.27 beats/min 22.66 45.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17510 381
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 406.64 beats/min 9.8 21.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17515 381
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 436.02 beats/min 34.89 85.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17527 381
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 408.35 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17542 381
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 412.88 beats/min 24.38 77.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17544 381
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 412.26 beats/min 10.5 27.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17549 381
Hsd:SD heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 416.89 beats/min 17.44 52.31 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 19295 381
SS.BN-(D13Rat20-D13Rat127)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 153.0 mmHg 4.7 16.28 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65168 15
SS.BN-(D13Rat20-D13Rat127)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 173.0 mmHg 6.1 21.13 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65169 15
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 124.63 mmHg 2.02 5.71 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19515 381
SS.BN-(D13Rat123-D13Rat197)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 166.0 mmHg 8.0 27.71 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65174 15
SS.BN-(D13Rat127-D13Rat61)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 187.0 mmHg 2.6 9.01 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65181 15
SS.BN-(D13Rat61-D13GRat197)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 168.0 mmHg 4.7 16.28 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65191 15
SS.BN-(D13Got51-D13Rat57)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 178.0 mmHg 4.3 14.9 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65194 15
FHH/EurMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 424.06 beats/min 12.62 30.91 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18195 381
FHH/EurMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 417.93 beats/min 18.7 49.49 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18200 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 102.13 mmHg 2.83 6.33 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20393 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 107.29 mmHg 1.35 3.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20399 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 84.02 beats/min 8.19 20.07 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20425 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 110.72 beats/min 14.28 34.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20427 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 80.79 beats/min 31.42 54.42 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20429 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 394.66 beats/min 17.27 38.62 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20441 381
Hsd:SD absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 2.58 mmHg 3.73 11.8 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 20446 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 568.16 beats/min 9.06 18.12 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20525 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 471.81 beats/min 40.33 57.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20533 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 558.42 beats/min 18.51 48.97 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20532 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 542.51 beats/min 6.08 13.6 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20534 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 152.73 beats/min 13.5 38.18 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19165 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 119.91 beats/min 10.84 30.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19167 381
Hsd:SD heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 539.93 beats/min 9.38 29.66 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 16120 381
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 441.09 beats/min 7.48 25.92 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16125 381
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 417.18 beats/min 29.61 88.83 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16126 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 1.8 mmHg 8.01 13.87 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16257 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 421.97 beats/min 11.37 27.85 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16350 381
LE/BluGill heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 431.1 beats/min 5.55 17.56 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16433 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 6.68 mmHg 5.35 11.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16774 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 5.11 mmHg 2.88 7.61 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16784 381
BN/OrlIcoCrlf diastolic blood pressure control condition Klimes I, et al., Diabetologia 2003 Mar;46(3):352-8. arterial blood pressure trait not specified 120.0 days 10 95.1 mmHg 1.23 3.9 vascular fluid filled catheter right common carotid artery 0.0 68983 1037
HTG systolic blood pressure control condition Klimes I, et al., Diabetologia 2003 Mar;46(3):352-8. arterial blood pressure trait not specified 120.0 days 10 156.7 mmHg 1.74 5.5 vascular fluid filled catheter right common carotid artery 0.0 68980 1037
SR/NEisSlc mean arterial blood pressure controlled sodium content diet (0.3 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 7 103.0 mmHg 3.0 7.94 vascular fluid filled catheter 0.0 102366 2687
SS/NEisSlc heart rate controlled sodium content diet (0.3 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 7 373.0 beats/min 8.0 21.17 vascular fluid filled catheter 0.0 102368 2687
SR/NEisSlc percent change in mean arterial blood pressure controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 7 -14.1 % 3.2 8.47 vascular fluid filled catheter 0.0 102378 2687
SS/NEisSlc percent change in heart rate controlled sodium content diet (8 %) (for 28 days) and hydralazine (4 mg/ml) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 7 -10.5 % 1.9 5.03 vascular fluid filled catheter 0.0 102387 2687
LH/Mav systolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 5 2hr mean (10a-12p) continuous mean 166.0 mmHg 3.0 6.71 vascular fluid filled catheter 0.0 103437 2825
SD mean arterial blood pressure control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. arterial blood pressure trait male 90.0 days 9 118.0 mmHg 5.0 15.0 vascular fluid filled catheter 0.0 101222 2582
SD mean arterial blood pressure control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. arterial blood pressure trait male 420.0 days-450.0 days 9 123.0 mmHg 12.0 36.0 vascular fluid filled catheter 0.0 101223 2582
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 14 148.0 mmHg 4.0 14.97 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100014 2398
Crl:WI(WU) mean arterial blood pressure thoracic aorta constriction Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 8 141.0 mmHg 8.0 22.63 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100015 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then quinapril (2 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 11 138.0 mmHg 5.0 16.58 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100016 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then losartan (3 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 14 144.0 mmHg 7.0 26.19 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100018 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 14 109.0 mmHg 3.0 11.22 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100022 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then losartan (3 mg/kg/d) (for 14 days) and icatibant (0.4 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 10 139.0 mmHg 8.0 25.3 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100019 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then quinapril (2 mg/kg/d) (for 14 days) and icatibant (0.4 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 11 100.0 mmHg 7.0 23.22 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100025 2398
SD-Nfe2l2em1Mcwi+/+ mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 35 and 49 days) Priestley JR, et al., Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H478-87. doi: 10.1152/ajpheart.00586.2015. Epub 2015 Dec 4. arterial blood pressure trait male 56.0 days-70.0 days 4 92.0 mmHg 2.8 5.6 vascular fluid filled catheter 0.0 100737 2520
SD-Nfe2l2em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 70 and 84 days) then controlled sodium chloride content diet (4 %) (for 3 days) then angiotensin II (100 ng/kg/min) (for 3 days) Priestley JR, et al., Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H478-87. doi: 10.1152/ajpheart.00586.2015. Epub 2015 Dec 4. arterial blood pressure trait male 62.0 days-76.0 days 5 97.0 mmHg 2.9 6.48 vascular fluid filled catheter 0.0 100742 2520
LL/Mav mean arterial blood pressure right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 350.0 days 7 119.0 mmHg 7.0 18.52 vascular fluid filled catheter 0.0 104576 2970
MNS mean arterial blood pressure control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 252.0 days 6 94.3 mmHg 1.1 2.7 vascular fluid filled catheter trunk of common carotid artery 0.0 104106 2907
MNS mean arterial blood pressure streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 84 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 168.0 days 6 94.8 mmHg 2.08 5.1 vascular fluid filled catheter trunk of common carotid artery 0.0 104103 2907
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 91.0 days 6 15sec/min for 3 hrs/day 175.5 mmHg 7.9 19.35 vascular fluid filled catheter 0.0 n=6-8 106522 3031
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 70.0 days 6 15sec/min for 3 hrs/day for 7days 127.7 mmHg 2.0 4.9 vascular fluid filled catheter 0.0 n=6-8 106521 3031
SS-Sh2b3em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) then controlled sodium chloride content diet (4 %) (for 21 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 91.0 days 6 15sec/min for 3 hrs/day 135.7 mmHg 1.1 2.69 vascular fluid filled catheter 0.0 n=6-8 106523 3031
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 5 MAP=.33(SP-DP) + DP 149.0 mmHg 4.0 8.94 vascular fluid filled catheter femoral artery 600.0 106776 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 5 444.0 beats/min 16.0 35.78 vascular fluid filled catheter femoral artery 600.0 106777 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 5 454.0 beats/min 7.0 15.65 vascular fluid filled catheter femoral artery 600.0 106775 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 5 466.0 beats/min 10.0 22.36 vascular fluid filled catheter femoral artery 600.0 106783 2685
SS-Sod3m1Mcwi right ventricular end-systolic blood pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart right ventricular blood pressure trait male 56.0 days 15 25.1 mmHg 0.53 2.05 vascular fluid filled catheter 0.0 106797 3032
SS/JrHsdMcwi heart rate vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart pumping trait male 56.0 days 6 358.0 beats/min 7.95 19.47 vascular fluid filled catheter 0.0 106798 3032
SS-Sod3m1Mcwi heart rate monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart pumping trait male 56.0 days 9 339.0 beats/min 15.2 45.6 vascular fluid filled catheter 0.0 106801 3032
SS/JrHsdMcwi systolic blood pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 6 115.0 mmHg 4.76 11.66 vascular fluid filled catheter 0.0 106802 3032
SS/JrHsdMcwi mean aortic pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 6 94.4 mmHg 4.27 10.46 vascular fluid filled catheter 0.0 Mean aortic pressure 106810 3032
SS-Chr 13BN/McwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 110.0 mmHg 2.0 4.0 vascular fluid filled catheter femoral artery 600.0 106761 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 5 MAP=.33(SP-DP) + DP 149.0 mmHg 3.0 6.71 vascular fluid filled catheter femoral artery 600.0 106768 2685
SS-Chr 13BN/McwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 408.0 beats/min 6.0 12.0 vascular fluid filled catheter femoral artery 600.0 106772 2685
LEW/SsNHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 9 95.0 mmHg 9.0 27.0 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107333 3077
FHH/EurMcwiCrl mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 137.0 mmHg 5.0 15.81 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107341 3077
NBL/CrCrl mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 136.0 mmHg 6.0 18.97 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107344 3077
WKY/NCrl absolute change in mean arterial blood pressure artificial cerebrospinal fluid (200 nl) then angiotensin II (90 ng) then candesartan (0.05 ug) (for 0.2 hours) then angiotensin II (90 ng) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait not specified  days 3 10.0 mmHg 3.0 5.2 vascular fluid filled catheter 0.0 110105 2685
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 130.43 mmHg 3.29 9.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15071 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 171.6 mmHg 3.29 8.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15081 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 125.37 mmHg 4.72 9.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15079 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 143.07 mmHg 9.43 28.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15082 381
SS-Chr 5BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 130.67 mmHg 13.02 26.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15085 381
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 151.71 mmHg 4.81 18.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15089 381
SS-Chr 3BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 137.53 mmHg 5.6 13.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15098 381
SS-Chr 15BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 135.04 mmHg 2.78 5.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15099 381
SS-Chr 3BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 140.86 mmHg 7.28 16.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15104 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 118.97 mmHg 3.11 10.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15121 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 133.22 mmHg 4.84 15.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15126 381
SS-Chr 4BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 127.54 mmHg 5.26 12.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15122 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 21.3 mmHg 5.11 14.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15144 381
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 5.05 mmHg 3.04 8.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15143 381
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 24.34 mmHg 5.03 13.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15150 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 22.53 mmHg 2.24 5.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15151 381
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 7.32 mmHg 6.4 11.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15156 381
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 14.67 mmHg 5.37 14.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15158 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 488.23 beats/min 17.24 24.38 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15193 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 473.85 beats/min 11.68 20.23 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15194 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 384.36 beats/min 62.94 109.01 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15196 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 134.91 mmHg 7.02 17.19 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15204 381
Hsd:SD absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 11.05 mmHg 4.96 12.15 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15481 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 18.8 mmHg 5.66 11.33 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15534 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 16.14 mmHg 6.33 14.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15538 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 124.87 mmHg 2.7 7.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15549 381
FHH/EurMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 425.52 beats/min 6.37 14.25 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15589 381
GH/OmrMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 430.92 beats/min 13.41 23.23 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15591 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 18.64 mmHg 7.01 9.91 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15762 381
Crl:CD(SD) heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 502.33 beats/min 11.19 27.42 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15784 381
LE/BluGill heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 469.54 beats/min 10.88 32.64 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15791 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 391.25 beats/min 7.75 21.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15920 381
SS-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 13 448.74 beats/min 5.34 19.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15928 381
FHH-Chr 19BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 427.24 beats/min 21.18 51.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15929 381
SS-Chr 3BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 441.68 beats/min 10.42 23.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15933 381
FHH-Chr 19BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 467.94 beats/min 25.25 56.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15935 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 406.22 beats/min 7.22 20.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15936 381
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 385.58 beats/min 9.77 32.41 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15336 381
FHH/EurMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 405.28 beats/min 8.17 23.12 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15337 381
SS-Chr 18BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 448.61 beats/min 12.78 33.82 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15340 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 116.98 mmHg 6.2 16.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14379 381
FHH/EurMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 126.12 mmHg 5.73 14.04 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14415 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 130.27 mmHg 2.33 6.17 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14666 381
SS-Chr 10BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 370.97 beats/min 8.92 26.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14673 381
FHH-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 367.71 beats/min 13.55 27.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14685 381
SS-Chr 17BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 468.65 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14689 381
FHH-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 345.61 beats/min 5.73 16.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14696 381
SHR/NCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 397.36 beats/min 9.06 25.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14690 381
SS-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 408.69 beats/min 12.64 37.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14701 381
SS-Chr 15BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 414.45 beats/min 11.11 22.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14702 381
FHH-Chr 8BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 309.12 beats/min 11.15 29.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14707 381
SS-Chr 3BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 444.24 beats/min 17.85 30.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14709 381
FHH-Chr 13BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 398.72 beats/min 21.14 42.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14708 381
SS-Chr 20BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 360.5 beats/min 7.85 26.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14715 381
FHH-Chr 13BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 338.07 beats/min 5.45 14.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14711 381
FHH-Chr 18BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 334.68 beats/min 15.4 34.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14713 381
FHH-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 390.9 beats/min 11.07 29.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15941 381
SS-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 466.52 beats/min 9.07 20.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15951 381
FHH-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 476.6 beats/min 61.06 86.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15965 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 271.02 beats/min 36.44 103.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15969 381
SS-Chr XBN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 444.42 beats/min 16.2 39.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15971 381
SS-Chr 2BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 424.03 beats/min 15.3 43.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15973 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 107.41 mmHg 2.55 4.42 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16025 381
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -21.91 beats/min 14.45 38.22 vascular fluid filled catheter 51679 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -49.56 beats/min 32.32 91.43 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51699 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -11.7 beats/min 12.08 34.18 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51700 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -63.92 beats/min 13.12 39.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51702 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -88.0 beats/min 18.35 55.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51712 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -36.4 beats/min 20.58 50.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51714 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -43.88 beats/min 13.58 33.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51721 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -38.37 beats/min 10.93 40.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51722 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -17.87 beats/min 15.63 44.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51720 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 14.83 mmHg 6.29 12.58 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51736 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 115.26 mmHg 1.79 4.0 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51743 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 16.32 mmHg 2.26 6.78 vascular fluid filled catheter 51765 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 23.85 mmHg 2.65 6.49 vascular fluid filled catheter 51766 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 31.28 mmHg 4.3 10.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51776 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 15.69 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51773 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 30.33 mmHg 2.51 5.03 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51778 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 22.37 mmHg 3.79 9.28 vascular fluid filled catheter 51787 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 15.53 beats/min 17.94 50.74 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51795 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 14.15 mmHg 3.4 8.34 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51812 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 3 23.81 mmHg 5.74 9.95 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51813 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 2 8.24 mmHg 7.11 10.05 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51818 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 116.75 mmHg 1.54 4.07 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51820 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 135.0 mmHg 5.04 21.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51821 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 123.09 mmHg 2.44 7.73 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51824 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -2.98 beats/min 11.84 35.51 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51846 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 21.98 mmHg 3.61 10.83 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51862 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 31.77 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51868 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 105.63 mmHg 1.68 5.03 vascular fluid filled catheter 51908 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 21.65 mmHg 1.26 2.52 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51910 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 -10.73 mmHg 2.75 6.14 vascular fluid filled catheter 51915 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -0.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51919 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -7.24 beats/min 8.54 33.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51920 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -30.53 beats/min 12.42 30.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51924 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -30.67 beats/min 12.69 49.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51925 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 21.3 beats/min 54.9 77.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51921 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -12.28 beats/min 7.95 19.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51929 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -5.13 beats/min 19.47 58.41 vascular fluid filled catheter 51939 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 4.62 mmHg 5.89 8.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51964 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -0.9 mmHg 1.72 4.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51967 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 25.27 mmHg 3.22 12.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51966 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 13.53 mmHg 3.99 10.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51969 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 3 1.67 beats/min 20.69 35.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51978 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 7.06 mmHg 2.33 6.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51970 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -14.03 beats/min 11.24 27.53 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51977 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -55.0 beats/min 29.4 41.58 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51980 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 4.17 mmHg 3.77 9.97 vascular fluid filled catheter 51992 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 130.75 mmHg 7.93 17.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51996 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 1.21 mmHg 4.28 11.33 vascular fluid filled catheter 52024 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -37.49 beats/min 6.24 18.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52047 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 -28.65 beats/min 9.43 39.99 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52049 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 -22.97 beats/min 15.42 53.41 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52052 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 75.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52053 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -11.07 beats/min 14.76 36.15 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52056 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -65.74 beats/min 24.24 72.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52057 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -6.75 beats/min 8.96 17.92 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52058 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 20 -76.99 beats/min 8.0 35.77 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52072 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -33.41 beats/min 13.0 39.01 vascular fluid filled catheter 52074 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -14.49 beats/min 8.94 23.64 vascular fluid filled catheter 52079 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 139.0 mmHg 3.96 15.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52087 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 104.25 mmHg 3.14 6.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52092 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 161.2 mmHg 3.09 9.28 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52833 482
SS-Chr 14BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 152.32 mmHg 5.38 16.15 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52831 482
SS-Chr 5BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 8 122.04 mmHg 2.16 6.11 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52842 482
SS-Chr 10BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 152.83 mmHg 6.82 20.46 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52838 482
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 5 154.32 mmHg 18.48 41.32 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52848 482
SS-Chr 11BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 14 162.26 mmHg 3.49 13.07 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52856 482
SS-Chr XBN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 5 167.1 mmHg 9.3 20.79 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52861 482
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 10 136.64 mmHg 1.45 4.58 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52862 482
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 159.75 mmHg 6.83 20.5 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52865 482
SS-Chr 19BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 6 163.66 mmHg 12.23 29.95 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52869 482
SS-Chr 2BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 10 150.38 mmHg 3.4 10.75 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52871 482
SS-Chr 2BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 174.74 mmHg 5.35 16.04 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52877 482
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 110.84 mmHg 1.12 3.36 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52874 482
FHH-Chr 5BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 5 428.9 beats/min 11.71 26.18 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52490 482
FHH-Chr 3BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 2 438.8 beats/min 13.17 18.62 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52489 482
FHH-Chr 2BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 5 419.9 beats/min 8.37 18.73 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52491 482
FHH-Chr 20BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 386.33 beats/min 10.29 27.22 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52499 482
FHH-Chr 18BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 442.33 beats/min 16.64 49.92 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52501 482
FHH-Chr 20BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 6 439.71 beats/min 5.33 13.06 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52502 482
FHH/EurMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 48 431.04 beats/min 4.26 29.51 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52505 482
FHH-Chr 4BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 5 446.87 beats/min 8.17 18.26 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52514 482
FHH-Chr 7BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 429.18 beats/min 10.25 30.75 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52528 482
FHH-Chr 1BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 10 440.48 beats/min 9.55 30.21 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52530 482
FHH-Chr 12BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 11 163.84 mmHg 7.46 24.74 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52531 482
FHH-Chr 19BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 6 142.3 mmHg 6.05 14.81 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52541 482
FHH-Chr 6BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 177.43 mmHg 5.03 15.09 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52540 482
FHH-Chr 6BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 7 150.74 mmHg 12.37 32.74 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52542 482
FHH-Chr 13BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 8 161.41 mmHg 6.33 17.92 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52545 482
FHH-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 148.57 mmHg 5.32 14.08 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52546 482
FHH-Chr 3BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 4 184.08 mmHg 15.31 30.63 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52554 482
FHH-Chr 12BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 12 189.93 mmHg 4.66 16.14 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52550 482
FHH-Chr 1BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 166.93 mmHg 4.8 14.41 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52560 482
FHH-Chr 1BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 10 155.42 mmHg 4.94 15.62 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52577 482
SS-Chr 7BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 10 392.42 beats/min 6.65 21.03 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52642 482
SS-Chr 10BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 386.64 beats/min 8.19 24.56 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52640 482
SS-Chr 3BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 5 420.97 beats/min 7.06 15.79 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52654 482
SS-Chr 13BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 18 382.3 beats/min 2.75 11.69 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52657 482
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 8 407.55 beats/min 8.67 24.52 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52660 482
SS-Chr 1BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 19 429.86 beats/min 4.64 20.25 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52665 482
SS-Chr 19BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 6 384.16 beats/min 17.74 43.46 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52671 482
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 32.45 beats/min 10.27 29.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50514 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -61.7 beats/min 18.98 50.22 vascular fluid filled catheter 50515 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 414.77 beats/min 14.05 34.41 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50526 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 423.68 beats/min 13.94 39.43 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50531 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 401.93 beats/min 10.77 30.46 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50532 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 3.84 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50545 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 104.1 mmHg 2.39 7.16 vascular fluid filled catheter 50548 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 110.54 mmHg 5.19 13.72 vascular fluid filled catheter 50549 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -33.83 beats/min 18.34 48.53 vascular fluid filled catheter 50550 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 425.43 beats/min 14.64 32.74 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50578 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -47.6 beats/min 14.39 35.25 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50592 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -47.96 beats/min 18.32 51.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50589 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -30.56 beats/min 50.56 101.11 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50593 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 2.83 mmHg 1.4 4.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50598 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 2.63 mmHg 2.19 4.39 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50609 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -4.12 beats/min 18.68 41.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50612 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 106.57 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50650 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 124.75 mmHg 1.05 3.31 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50649 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 34.17 mmHg 2.14 5.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50656 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 411.76 beats/min 26.24 52.48 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50667 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 125.38 mmHg 2.94 6.57 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50677 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 4.48 mmHg 2.3 6.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50697 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -0.89 mmHg 3.73 9.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50698 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 4.57 mmHg 2.78 8.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50703 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 336.19 beats/min 5.56 16.67 vascular fluid filled catheter 50710 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 371.77 beats/min 15.21 40.24 vascular fluid filled catheter 50708 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 0.72 mmHg 2.7 7.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50706 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 135.75 mmHg 2.92 7.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50733 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 144.0 mmHg 3.04 12.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50734 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 131.76 mmHg 1.99 7.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50741 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 102.53 mmHg 2.47 6.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50746 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 16 138.36 mmHg 2.86 11.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50743 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 138.48 mmHg 2.12 5.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50744 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 28.78 mmHg 3.03 10.51 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50755 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 25.72 mmHg 4.1 11.6 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50758 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -7.12 mmHg 7.1 18.77 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50763 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 3.0 mmHg 6.88 16.84 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50767 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 3 -6.83 mmHg 2.51 4.35 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50765 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 0.93 mmHg 2.33 6.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50780 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 5.65 mmHg 0.84 1.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50782 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 43.49 mmHg 2.68 6.55 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50786 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 16.67 beats/min 10.47 39.18 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50791 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 119.61 mmHg 1.83 4.85 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50798 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 142.26 mmHg 3.59 10.14 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50799 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 13 -9.41 mmHg 2.27 8.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50805 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 2.03 mmHg 7.31 14.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50811 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 2.72 beats/min 8.95 33.48 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50824 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 61.4 beats/min 12.22 29.94 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50821 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 0.02 mmHg 3.23 8.55 vascular fluid filled catheter 50831 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 14.15 mmHg 3.96 11.89 vascular fluid filled catheter 50828 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -6.9 beats/min 15.96 47.88 vascular fluid filled catheter 50834 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -112.24 beats/min 36.62 89.69 vascular fluid filled catheter 50835 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 103.89 mmHg 5.5 16.51 vascular fluid filled catheter 50836 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 0.64 mmHg 2.4 5.89 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50840 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -24.64 beats/min 8.37 31.31 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50847 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -1.91 mmHg 0.73 1.92 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50850 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 16.23 mmHg 3.7 7.41 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50859 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -48.95 beats/min 23.61 47.22 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50865 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 37.0 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50868 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 389.31 beats/min 12.58 28.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50877 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 35.66 mmHg 2.83 6.34 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50873 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 31.24 mmHg 2.72 7.19 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50876 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 419.89 beats/min 5.87 17.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50880 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 38.89 mmHg 2.68 7.09 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50874 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 357.13 beats/min 8.47 20.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50883 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 392.72 beats/min 8.3 16.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50890 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 393.96 beats/min 5.0 14.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50884 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 10.88 beats/min 6.24 13.95 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50904 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 10.04 mmHg 1.85 7.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50913 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 8.16 mmHg 3.34 10.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50911 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 10.49 mmHg 2.42 9.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50916 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 6.66 mmHg 2.3 7.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50918 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 4.68 mmHg 2.12 5.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50920 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 176.45 mmHg 4.45 11.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50945 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 128.48 mmHg 4.68 11.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50946 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 109.15 mmHg 2.9 7.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50950 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 137.12 mmHg 4.62 13.86 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50947 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 13.28 mmHg 2.14 8.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50958 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 28.71 mmHg 4.76 12.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50967 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -49.54 beats/min 10.68 39.97 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50974 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -6.56 beats/min 8.43 18.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50980 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 12.15 beats/min 5.65 13.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50982 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 36.95 beats/min 7.33 14.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50987 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -0.24 mmHg 4.62 12.21 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50999 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 17 12.53 mmHg 2.38 9.83 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51020 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 1.89 mmHg 2.65 9.18 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51026 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 11.67 mmHg 1.81 5.73 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51024 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -15.18 beats/min 19.55 58.66 vascular fluid filled catheter 51042 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 20 -1.58 mmHg 1.98 8.83 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51038 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 -3.09 mmHg 3.77 9.23 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51065 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -5.54 mmHg 2.16 6.48 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51066 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -31.9 beats/min 13.55 33.19 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51069 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 107.21 mmHg 2.57 6.79 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51078 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 0.65 mmHg 2.07 5.48 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51084 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 2.47 beats/min 9.71 25.69 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51087 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 68.68 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51097 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 437.61 beats/min 9.33 26.38 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51113 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 432.92 beats/min 10.44 36.17 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51119 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 20 -41.72 beats/min 7.75 34.65 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51125 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -100.68 beats/min 11.02 42.68 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51126 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 0.1 mmHg 1.74 4.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51136 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 8.88 mmHg 3.75 7.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51137 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 126.1 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51143 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -10.16 beats/min 11.77 26.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51153 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -13.39 beats/min 9.16 18.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51159 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 25.24 mmHg 4.55 12.05 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51169 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 16 15.97 mmHg 2.94 11.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51184 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 18.38 mmHg 3.39 8.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51187 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 20.52 mmHg 3.91 9.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51191 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 27.1 mmHg 4.91 19.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51193 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 23.97 mmHg 6.39 12.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51189 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 17.52 mmHg 4.28 11.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51195 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -14.12 beats/min 16.27 36.37 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51198 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 -34.17 beats/min 7.73 24.44 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51203 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -7.12 beats/min 15.73 44.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51206 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -60.76 beats/min 16.42 46.43 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51207 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -16.65 beats/min 19.02 57.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51210 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -63.5 beats/min 10.14 39.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51227 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -79.11 beats/min 25.39 71.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51230 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 10.55 beats/min 16.42 63.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51233 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -21.84 beats/min 4.82 18.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51236 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 383.32 beats/min 7.64 20.22 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51243 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 383.68 beats/min 7.38 31.32 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51245 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 355.95 beats/min 5.94 15.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51252 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 3 388.81 beats/min 6.13 10.62 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51255 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 385.71 beats/min 6.11 16.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51279 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 10 415.95 beats/min 4.14 13.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51282 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 394.28 beats/min 8.05 32.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51289 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -55.5 beats/min 21.44 52.51 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51302 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 105.29 mmHg 2.43 5.43 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51323 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 108.6 mmHg 0.71 1.58 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51326 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -7.69 beats/min 11.36 30.07 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51331 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 147.84 mmHg 6.57 16.08 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51329 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 15.83 mmHg 5.72 12.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51335 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 17.99 mmHg 2.07 6.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51334 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 32.05 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51338 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 17.74 mmHg 6.47 12.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51346 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -27.23 beats/min 9.2 35.65 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51350 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 20.68 mmHg 2.71 8.13 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51347 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -11.5 beats/min 12.54 37.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51351 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -34.31 beats/min 11.52 30.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51355 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -31.11 beats/min 10.51 40.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51358 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 2.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51372 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 432.9 beats/min 8.18 21.65 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51381 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 3 465.42 beats/min 20.72 35.89 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51383 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 412.44 beats/min 11.88 29.1 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51385 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 389.36 beats/min 16.31 48.94 vascular fluid filled catheter 51386 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 368.95 beats/min 11.17 29.55 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51384 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 109.0 mmHg 4.18 8.37 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51390 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 112.47 mmHg 2.22 5.45 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51391 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 2.21 mmHg 3.42 9.04 vascular fluid filled catheter 51395 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -1.66 mmHg 4.53 11.99 vascular fluid filled catheter 51397 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 14 8.24 beats/min 8.8 32.91 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51401 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 3 -20.8 beats/min 34.71 60.12 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51405 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 2 69.8 beats/min 42.0 59.4 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51410 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -31.0 beats/min 19.2 50.79 vascular fluid filled catheter 51414 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 17 30.86 mmHg 2.26 9.32 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51421 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 36.49 mmHg 4.28 11.32 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51422 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 38.87 mmHg 3.52 9.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51428 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 364.9 beats/min 8.85 23.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51486 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 33.19 mmHg 3.65 5.16 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51491 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 28.44 mmHg 4.62 11.33 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51488 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 3.5 mmHg 5.0 12.25 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51494 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -81.81 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51505 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -16.02 beats/min 14.65 43.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51508 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -22.2 beats/min 16.32 46.15 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51512 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -48.94 beats/min 12.72 33.65 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51530 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 1.67 beats/min 21.69 57.39 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51531 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 400.82 beats/min 9.27 39.31 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51577 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 365.3 beats/min 2.73 8.62 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51581 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 437.8 beats/min 17.4 49.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51588 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -0.31 mmHg 3.26 7.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51594 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 12.82 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51593 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 -3.67 mmHg 4.19 11.86 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51598 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 3 -12.6 beats/min 13.02 22.55 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51608 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -22.14 beats/min 6.77 25.31 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51614 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -169.1 beats/min 12.5 17.68 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51610 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -57.24 beats/min 12.15 27.17 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51611 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 393.45 beats/min 27.31 61.07 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51616 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -1.38 mmHg 1.79 4.73 vascular fluid filled catheter 51623 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -1.31 mmHg 3.14 9.41 vascular fluid filled catheter 51622 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 25.88 mmHg 1.67 2.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51660 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 32.43 mmHg 3.05 11.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51659 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 28.46 mmHg 1.34 5.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51664 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 21.07 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51661 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 23.04 mmHg 2.89 8.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51666 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 396.6 beats/min 21.2 29.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50324 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 414.38 beats/min 10.05 30.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50321 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 3.31 mmHg 1.5 5.62 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50341 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -40.59 beats/min 39.51 88.34 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50345 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 112.19 mmHg 3.96 10.47 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50352 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 8.0 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50354 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -47.44 beats/min 16.66 49.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50353 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -46.72 beats/min 12.48 48.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50360 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -23.6 beats/min 13.04 31.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50359 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -53.43 beats/min 9.22 35.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50358 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -34.84 beats/min 18.09 51.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50362 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 16 6.75 mmHg 1.79 7.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50366 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 17.21 mmHg 4.74 9.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50371 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 13.96 mmHg 1.62 4.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50374 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 1.89 mmHg 4.18 11.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50372 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 0.65 mmHg 3.15 8.34 vascular fluid filled catheter 50379 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 3.56 mmHg 2.47 7.4 vascular fluid filled catheter 50381 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 12.31 mmHg 3.92 7.83 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50385 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -10.18 beats/min 11.58 32.74 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50418 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 -35.02 beats/min 11.98 50.83 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50419 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -57.2 beats/min 18.02 40.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50420 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 -34.09 beats/min 18.25 63.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50422 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -47.58 beats/min 14.04 48.64 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50424 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -8.48 beats/min 15.29 43.23 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50429 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 0.44 mmHg 2.74 7.75 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50435 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 410.27 beats/min 18.86 46.2 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50446 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 1.04 mmHg 1.62 3.61 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50451 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 2.4 mmHg 2.82 7.45 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50454 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 386.28 beats/min 7.72 30.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50471 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 414.07 beats/min 11.47 28.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50478 481
SS-Chr 13BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 375.78 beats/min 13.65 38.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14719 381
SS-Chr YBN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 402.09 beats/min 17.32 69.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14720 381
FHH-Chr 11BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 678.48 beats/min 167.28 374.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14729 381
SS-Chr 12BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 394.16 beats/min 29.1 41.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14732 381
FHH-Chr 7BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 438.15 beats/min 0.54 0.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14735 381
SS-Chr 2BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 404.44 beats/min 17.49 52.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14736 381
FHH-Chr 7BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 351.65 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14742 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 heart rate during walking-heart rate during rest 108.21 beats/min 13.25 37.48 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13381 381
SS-Chr 6BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 heart rate during walking-heart rate during rest 76.11 beats/min 6.58 26.31 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13385 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 heart rate during walking-heart rate during rest 93.08 beats/min 5.2 20.15 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13388 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 37 heart rate during walking-heart rate during rest 82.39 beats/min 5.02 30.53 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13397 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 heart rate during walking-heart rate during rest 88.1 beats/min 5.97 11.94 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13399 381
SS-Chr 7BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 heart rate during walking-heart rate during rest 87.77 beats/min 15.1 39.96 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13401 381
FHH-Chr 1BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 heart rate during walking-heart rate during rest 91.08 beats/min 15.45 43.71 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13398 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 heart rate during walking-heart rate during rest 123.09 beats/min vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13404 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 heart rate during walking-heart rate during rest 94.5 beats/min 11.11 40.05 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13410 381
F344/DuCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 119.59 mmHg 7.49 18.34 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13457 381
SS-Chr 14BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 124.97 mmHg 2.86 7.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13462 381
SS-Chr 17BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 121.03 mmHg 5.22 10.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13471 381
SHR/NCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 161.74 mmHg 5.21 14.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13477 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 116.01 mmHg 3.31 9.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13483 381
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 13 117.64 mmHg 3.38 12.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13485 381
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 123.2 mmHg 7.17 14.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13489 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 115.06 mmHg 9.52 21.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13492 381
SS-Chr 3BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 113.71 mmHg 1.64 2.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13496 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 119.08 mmHg 3.91 10.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13498 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 125.97 mmHg 6.67 14.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13500 381
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 112.41 mmHg 5.67 15.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13499 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 122.0 mmHg 5.68 13.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13501 381
SS-Chr XBN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 96.77 mmHg 10.35 17.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13511 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 112.59 mmHg 3.72 12.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13509 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 121.8 mmHg 3.03 9.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13515 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 123.73 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13529 381
SS-Chr 2BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 125.46 mmHg 2.88 8.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13530 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 115.24 mmHg 4.79 12.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13531 381
WKY/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 29.5 mmHg 5.62 12.58 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14284 381
Hsd:SD absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 7.43 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14285 381
F344/DuCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 14.87 mmHg 3.2 7.84 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14287 381
LEW/Crl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 26.99 mmHg 2.05 5.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14288 381
SS-Chr 10BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 105.02 mmHg 4.12 12.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14303 381
SS-Chr 14BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 124.55 mmHg 3.93 10.4 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14306 381
SS-Chr 17BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 132.57 mmHg 5.02 10.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14321 381
FHH/EurMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 109.41 mmHg 4.87 16.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14333 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 115.43 mmHg 1.82 4.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14341 381
SS-Chr 3BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 140.79 mmHg 7.38 16.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14342 381
SS-Chr 11BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 125.86 mmHg 4.39 10.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14354 381
FHH-Chr 4BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 135.55 mmHg 26.8 37.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14362 381
SS-Chr 4BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 131.85 mmHg 3.76 11.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14368 381
SS-Chr 12BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 119.54 mmHg 16.45 36.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14366 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 127.57 mmHg 4.97 17.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14372 381
BN/NHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 14 119.99 mmHg 5.02 18.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14374 381
LEW/Crl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 136.08 beats/min 15.39 37.69 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17294 381
F344/DuCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 79.39 beats/min 11.46 22.91 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17296 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 104.88 mmHg 6.15 16.26 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13769 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 115.2 mmHg 5.59 14.8 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13771 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 440.03 beats/min 10.25 14.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13796 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 500.97 beats/min 26.64 59.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13803 381
FHH-Chr 1BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 499.19 beats/min 11.73 40.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13815 381
BN/NHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 104.25 mmHg 2.28 5.1 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13895 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 113.81 mmHg vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13901 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 99.54 mmHg 1.26 2.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13904 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 123.11 mmHg 13.43 18.99 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13905 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 497.77 beats/min 4.55 13.64 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14063 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 548.23 beats/min 8.75 23.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14067 381
GH/OmrMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 170.05 mmHg 8.93 21.87 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14127 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 116.81 beats/min vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14102 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 78.67 beats/min 3.46 6.0 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14104 381
Crl:CD(SD) absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 99.99 beats/min 6.52 17.26 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14114 381
LEW/Crl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 14 93.4 beats/min 9.02 33.76 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14111 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 106.74 mmHg 3.46 4.89 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14122 381
F344/DuCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 71.79 beats/min 10.6 33.53 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14118 381
SHRSP/Gcrc systolic blood pressure control condition Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 91.0 days-126.0 days 13 187.3 mmHg 3.27 11.79 vascular fluid filled catheter abdominal aorta 3024000 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 35 days 12728 302
SHRSP.WKY-(D2Mit21-D2Rat157)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 126.0 days-147.0 days 7 195.9 mmHg 1.53 4.05 vascular fluid filled catheter abdominal aorta 1814400 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 21 days 12733 302
SHRSP.WKY-(D2Wox9-D2Mgh12)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 126.0 days-147.0 days 12 218.2 mmHg 7.28 25.22 vascular fluid filled catheter abdominal aorta 1814400 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 21 days 12735 302
SHR/N systolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait male 84.0 days 14 176.0 mmHg 8.0 29.93 vascular fluid filled catheter right carotid 13043 327
SHR/N diastolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait male 84.0 days 14 139.0 mmHg 4.0 14.97 vascular fluid filled catheter right carotid 13044 327
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 130.99 mmHg 4.35 13.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19704 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 125.15 mmHg 9.63 25.47 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19710 381
SS-Chr 14BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 125.98 mmHg 3.04 8.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19843 381
SS-Chr 9BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 120.59 mmHg 1.65 5.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19845 381
SS-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 131.52 mmHg 5.13 10.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19852 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 130.38 mmHg 6.47 15.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19856 381
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 136.75 mmHg 7.74 26.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19863 381
SS-Chr 15BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 121.41 mmHg 6.21 12.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19870 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 109.08 mmHg 2.17 6.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19869 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 121.61 mmHg 4.79 12.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19879 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 124.11 mmHg 2.15 5.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19884 381
SS-Chr 3BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 114.48 mmHg 5.52 9.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19877 381
SS-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 122.35 mmHg 3.6 11.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19883 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 121.66 mmHg 6.27 15.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19882 381
SS-Chr 4BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 128.16 mmHg 4.59 11.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19895 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 110.17 mmHg 4.94 15.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19894 381
FHH-Chr 1BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 17.31 mmHg 2.31 6.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20730 381
SS-Chr 7BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 28.41 mmHg 3.51 9.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20731 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 36.58 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20736 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 8.82 mmHg 1.21 3.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20734 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 13.71 mmHg 3.17 10.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20741 381
SS-Chr 7BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 18.31 mmHg 3.53 11.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20738 381
FHH-Chr 1BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 18.22 mmHg 2.88 9.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20744 381
FHH-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 448.12 beats/min 17.71 35.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20908 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 379.64 beats/min 16.59 46.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20913 381
SS-Chr 15BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 411.73 beats/min 19.27 38.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20926 381
FHH-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 395.8 beats/min 22.88 56.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20931 381
SS-Chr 3BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 402.36 beats/min 12.37 27.65 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20933 381
FHH-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 408.9 beats/min 8.72 23.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20938 381
SS-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 432.36 beats/min 27.78 68.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20945 381
FHH-Chr 4BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 349.97 beats/min 85.02 120.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20953 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 404.48 beats/min 8.98 28.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20955 381
SS-Chr XBN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 409.11 beats/min 12.12 32.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20967 381
FHH-Chr 1BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 476.99 beats/min 8.09 22.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20970 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 395.98 beats/min 9.13 24.16 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20978 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 436.5 beats/min 7.29 19.29 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20977 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 77.68 beats/min 15.59 34.85 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20994 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 109.63 beats/min 15.94 22.54 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20995 381
SS-Chr 4BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 122.04 mmHg 4.94 13.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19902 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 116.32 mmHg 10.58 18.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19901 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 534.88 beats/min 0.41 0.72 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19935 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 574.27 beats/min 5.79 10.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19961 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 515.08 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19958 381
SS-Chr 13BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 99.45 mmHg 3.74 9.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20048 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 113.83 mmHg 3.8 10.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20056 381
F344/DuCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 16.59 mmHg 3.58 9.46 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20106 381
LE/BluGill absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 9.34 mmHg 1.42 4.02 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20108 381
F344/DuCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 419.77 beats/min 7.28 26.24 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19541 381
LE/BluGill heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 426.33 beats/min 15.98 47.93 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19543 381
F344/DuCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 124.14 mmHg 2.74 6.71 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17600 381
LEW/Crl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 124.47 mmHg 4.89 11.99 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17601 381
F344/DuCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 106.95 mmHg 3.69 7.37 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17603 381
WKY/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 103.69 mmHg 4.74 8.22 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17602 381
FHH/EurMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 386.16 beats/min 34.85 49.28 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17667 381
SS-Chr 20BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 13 440.69 beats/min 8.58 30.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17727 381
LEW/Crl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 318.19 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17730 381
SS-Chr 9BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 412.31 beats/min 8.61 25.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17732 381
SS-Chr 9BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 418.71 beats/min 10.19 30.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17736 381
SS-Chr 20BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 412.69 beats/min 8.44 26.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17738 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 460.14 beats/min 26.8 59.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17747 381
SHR/NCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 421.83 beats/min 16.26 45.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17749 381
SS-Chr 2BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 414.56 beats/min 7.88 27.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17754 381
SS-Chr 2BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 402.23 beats/min 7.1 24.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17759 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 160.48 mmHg 8.36 22.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17771 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 171.5 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17773 381
F344/DuCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 385.41 beats/min 7.25 20.5 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18082 381
LE/BluGill heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 286.83 beats/min 27.66 78.25 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18088 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 449.47 beats/min 14.97 36.66 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18109 381
SS.BN-(D13Rat7-D13Rat88)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 165.0 mmHg 4.2 14.55 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65161 15
SS.BN-(D13Rat20-D13Got22)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 192.0 mmHg 2.8 9.7 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65164 15
SS-Chr 20BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 87.03 beats/min 13.61 38.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18350 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 22 113.5 beats/min 11.48 53.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18352 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 96.05 beats/min 3.86 7.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18355 381
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 98.71 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18356 381
SS-Chr 9BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 107.97 beats/min 27.45 47.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18363 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 135.23 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18362 381
WKY/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 366.51 beats/min 19.08 60.32 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18384 381
Crl:CD(SD) heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 428.96 beats/min 14.47 40.93 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18389 381
Hsd:SD heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 415.31 beats/min 4.45 12.59 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 18748 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 491.55 beats/min 15.67 35.05 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18756 381
LEW/Crl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 14 110.97 mmHg 2.56 9.57 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18764 381
Crl:CD(SD) mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 110.96 mmHg 3.9 11.04 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18765 381
WKY/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 117.99 mmHg 6.28 15.39 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18770 381
LEW/Crl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 18 89.62 mmHg 2.11 8.96 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18775 381
Hsd:SD mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 101.48 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18774 381
Crl:CD(SD) mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 99.83 mmHg 1.4 3.71 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18778 381
LE/BluGill mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 107.52 mmHg 1.47 4.87 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18783 381
WKY/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 520.54 beats/min 3.35 7.49 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18792 381
F344/DuCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 522.3 beats/min 2.74 5.48 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18798 381
Hsd:SD mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 105.72 mmHg 3.67 11.62 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 18926 381
LEW/Crl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 114.72 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18931 381
SS-Chr 6BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 124.39 mmHg 2.37 9.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18932 381
SS-Chr 20BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 115.64 mmHg 9.38 24.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18939 381
SS-Chr 9BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 125.92 mmHg 4.3 13.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18937 381
SS-Chr 13BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 119.25 mmHg 4.64 12.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18941 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 135.91 mmHg 6.19 17.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18945 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 138.76 mmHg 3.17 10.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18956 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 112.73 mmHg 4.33 7.5 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19005 381
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 436.17 beats/min 14.55 38.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17479 381
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 393.11 beats/min 14.21 42.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17488 381
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 421.09 beats/min 14.92 49.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17486 381
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 425.92 beats/min 18.65 52.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17489 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 402.69 beats/min 19.15 50.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17495 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 447.79 beats/min 11.25 22.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17492 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 427.79 beats/min 11.17 43.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17500 381
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 394.45 beats/min 17.93 50.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17503 381
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 434.94 beats/min 9.88 31.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17505 381
SS-Chr 15BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 397.64 beats/min 9.71 19.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17508 381
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 423.4 beats/min 19.24 47.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17513 381
FHH-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 396.11 beats/min 19.99 59.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17517 381
SS-Chr XBN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 372.01 beats/min 20.08 49.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17530 381
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 448.23 beats/min 13.23 34.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17533 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 400.39 beats/min 11.33 37.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17532 381
SS-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 437.1 beats/min 20.79 41.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17538 381
SS-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 425.87 beats/min 11.22 33.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17541 381
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 381.44 beats/min 11.69 30.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17540 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 226.69 beats/min 13.62 49.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17547 381
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 467.14 beats/min 24.71 65.38 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17552 381
Hsd:SD mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 108.45 mmHg 3.18 8.4 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 19310 381
Hsd:SD mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 108.29 mmHg 2.16 6.83 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 19311 381
SS.BN-(D13Rat115-D13Rat61)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 155.0 mmHg 3.6 12.47 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65172 15
SS.BN-(D13Rat123-D13Rat197)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 142.0 mmHg 4.8 16.63 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65175 15
SS.BN-(D13Rat91-D13Got45)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 172.0 mmHg 3.2 11.09 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65177 15
SS.BN-(D13Rat178-D13Got45)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 190.0 mmHg 2.8 9.7 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65185 15
SS.BN-(D13Rat127-D13Rat46)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 165.0 mmHg 4.5 15.59 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65189 15
SS.BN-(D13Got51-D13Rat192)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 168.0 mmHg 1.4 4.85 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65192 15
SHRSP.WKY-(D1Wox29-D1Arb21)/Izm mean arterial blood pressure control condition Yao H, et al., Physiol Genomics. 2007 Feb 27;. arterial blood pressure trait male 150.0 days 15 212.0 mmHg 5.94 23.0 vascular fluid filled catheter right femoral artery 0 65289 567
SHRSP/Izm mean arterial blood pressure control condition Yao H, et al., Physiol Genomics. 2007 Feb 27;. arterial blood pressure trait male 150.0 days 17 241.0 mmHg 5.34 22.0 vascular fluid filled catheter right femoral artery 0 65293 567
SS-Chr 16BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 430.17 beats/min 9.69 23.73 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18199 381
BN/NHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 394.7 beats/min 20.25 35.08 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18201 381
BN/NHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 441.08 beats/min 11.92 26.64 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18202 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 110.83 mmHg 3.46 8.48 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20395 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 122.6 mmHg 8.28 21.9 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20403 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 119.97 beats/min 25.76 51.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20432 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 43.49 beats/min 12.01 31.77 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20431 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 436.11 beats/min 8.76 23.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20437 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 452.61 beats/min 5.11 16.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20443 381
Hsd:SD absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 2.34 mmHg 3.47 9.17 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 20445 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 565.64 beats/min 9.72 27.48 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20526 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 549.71 beats/min 4.91 9.82 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20536 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 565.48 beats/min 13.86 33.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20530 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 574.36 beats/min 4.48 11.85 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20535 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 96.37 beats/min 51.17 72.37 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19172 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 168.16 beats/min 19.86 48.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19170 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 140.49 beats/min 33.33 88.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19171 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 101.43 beats/min 12.22 27.32 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19173 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 153.5 beats/min 14.22 31.79 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19166 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 86.7 beats/min 12.11 32.05 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19174 381
Hsd:SD heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 410.89 beats/min 17.95 25.39 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16122 381
LE/BluGill heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 370.38 beats/min 12.06 36.18 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16127 381
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 356.09 beats/min 15.89 61.56 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16129 381
LEW/Crl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 349.17 beats/min 11.05 44.2 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16128 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 11.05 mmHg 2.35 4.08 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16253 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 28.15 mmHg vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16252 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 4.7 mmHg 1.87 2.64 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16254 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 19.79 mmHg 4.48 10.98 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16258 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 14.99 mmHg 1.74 2.46 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16256 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 436.42 beats/min 9.9 28.0 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16352 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 470.71 beats/min 10.79 28.54 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16355 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 373.44 beats/min 11.81 20.46 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16358 381
F344/DuCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 429.36 beats/min 6.47 22.41 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16436 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 14.63 mmHg 2.37 5.81 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16778 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 24.0 mmHg 5.79 11.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16785 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 138.1 mmHg 11.69 16.53 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16028 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 109.52 mmHg 2.72 6.08 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16027 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 124.53 mmHg 0.29 0.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16026 381
BN/OrlIcoCrlf systolic blood pressure control condition Klimes I, et al., Diabetologia 2003 Mar;46(3):352-8. arterial blood pressure trait not specified 120.0 days 10 114.9 mmHg 1.08 3.4 vascular fluid filled catheter right common carotid artery 0.0 68981 1037
HTG diastolic blood pressure control condition Klimes I, et al., Diabetologia 2003 Mar;46(3):352-8. arterial blood pressure trait not specified 120.0 days 10 130.5 mmHg 1.23 3.9 vascular fluid filled catheter right common carotid artery 0.0 68982 1037
SS/NEisSlc mean arterial blood pressure controlled sodium content diet (0.3 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 7 119.0 mmHg 4.0 10.58 vascular fluid filled catheter 0.0 102364 2687
SS/NEisSlc heart rate controlled sodium content diet (8 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 8 381.0 beats/min 8.0 22.63 vascular fluid filled catheter 0.0 102369 2687
SR/NEisSlc percent change in mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 6 -9.6 % 1.7 4.16 vascular fluid filled catheter 0.0 102379 2687
SS/NEisSlc percent change in mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 8 -29.1 % 4.8 13.58 vascular fluid filled catheter 0.0 102377 2687
SR/NEisSlc percent change in heart rate controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 7 -6.0 % 3.1 8.2 vascular fluid filled catheter 0.0 102382 2687
SS/NEisSlc mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) and hydralazine (4 mg/ml) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 7 110.0 mmHg 5.0 13.23 vascular fluid filled catheter 0.0 102384 2687
SR/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female  days 125.0 mmHg 2.0 vascular fluid filled catheter 0.0 102208 2681
SS/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female  days 129.0 mmHg 5.0 vascular fluid filled catheter 0.0 102210 2681
SS/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female  days 135.0 mmHg 4.0 vascular fluid filled catheter 0.0 102211 2681
SS/NEisSlc heart rate controlled sodium content diet (8 %) (for 28 days) and hydralazine (4 mg/ml) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 7 398.0 beats/min 13.0 34.39 vascular fluid filled catheter 0.0 102385 2687
LH/Mav diastolic blood pressure controlled perindopril content drinking water (0.4 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 6 2hr mean (10a-12p) continuous mean 110.0 mmHg 3.0 7.35 vascular fluid filled catheter 0.0 103442 2825
LL/Mav mean arterial blood pressure bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 35.0 days 9 86.0 mmHg 3.0 9.0 vascular fluid filled catheter 0.0 104572 2970
LL/Mav mean arterial blood pressure right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 112.0 days 6 111.0 mmHg 3.0 7.35 vascular fluid filled catheter 0.0 104574 2970
LL/Mav mean arterial blood pressure right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 112.0 days 6 111.0 mmHg 3.0 7.35 vascular fluid filled catheter 0.0 104598 2970
MNS mean arterial blood pressure streptozotocin (55 mg/kg) then insulin (4 IU/kg) (for 168 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 252.0 days 6 94.4 mmHg 0.98 2.4 vascular fluid filled catheter trunk of common carotid artery 0.0 104107 2907
SS/JrHsdMcwi right ventricular end-systolic blood pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart right ventricular blood pressure trait male 56.0 days 11 48.6 mmHg 1.8 5.97 vascular fluid filled catheter 0.0 106638 3032
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 109.0 mmHg 3.0 6.0 vascular fluid filled catheter femoral artery 600.0 106756 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 444.0 beats/min 7.0 14.0 vascular fluid filled catheter femoral artery 600.0 106774 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then 2% dimethyl sulfoxide in artificial cerebrospinal fluid (300 nl/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 442.0 beats/min 5.0 10.0 vascular fluid filled catheter femoral artery 600.0 106778 2685
SS-Chr 13BN/McwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 5 425.0 beats/min 12.0 26.83 vascular fluid filled catheter femoral artery 600.0 106781 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 459.0 beats/min 9.0 18.0 vascular fluid filled catheter femoral artery 600.0 106782 2685
SS/JrHsdMcwi diastolic blood pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 6 84.0 mmHg 4.05 9.92 vascular fluid filled catheter 0.0 106806 3032
SS-Sod3m1Mcwi systolic blood pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 9 109.0 mmHg 3.82 11.46 vascular fluid filled catheter 0.0 106805 3032
SS-Chr 13BN/McwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 106.0 mmHg 4.0 8.0 vascular fluid filled catheter femoral artery 600.0 106759 2685
SS-Chr 13BN/McwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 104.0 mmHg 3.0 6.0 vascular fluid filled catheter femoral artery 600.0 106763 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 109.0 mmHg 2.0 4.0 vascular fluid filled catheter femoral artery 600.0 106767 2685
SS-Chr 13BN/McwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 5 421.0 beats/min 10.0 22.36 vascular fluid filled catheter femoral artery 600.0 106773 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) then kynurenate (0.14 ug/min) (for 0.2 hours) then candesartan (0.5 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 5 MAP=.33(SP-DP) + DP 128.0 mmHg 6.0 13.42 vascular fluid filled catheter femoral artery 600.0 106769 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 442.0 beats/min 4.0 8.0 vascular fluid filled catheter femoral artery 600.0 106770 2685
BN/HsdMcwiCrl mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 11 116.0 mmHg 2.0 6.63 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107330 3077
DA/OlaHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 9 144.0 mmHg 4.0 12.0 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107337 3077
WKY/NCrl absolute change in mean arterial blood pressure artificial cerebrospinal fluid (200 nl) then angiotensin II (90 ng) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait not specified  days 7 16.0 mmHg 2.0 5.29 vascular fluid filled catheter 0.0 110104 2685
SS-Chr 10BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 116.4 mmHg 2.18 6.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15065 381
SS-Chr 9BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 123.13 mmHg 2.1 5.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15070 381
FHH-Chr 6BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 121.15 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15072 381
SS-Chr 14BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 127.89 mmHg 2.13 6.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15073 381
SS-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 137.24 mmHg 6.69 13.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15083 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 119.35 mmHg 2.42 6.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15092 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 126.74 mmHg 3.35 9.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15108 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 126.23 mmHg 2.38 6.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15109 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 15 126.23 mmHg 3.6 13.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15120 381
SS-Chr 19BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 123.99 mmHg 7.48 14.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15127 381
SS-Chr 19BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 134.49 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15131 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 14 117.38 mmHg 4.81 18.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15137 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 22.43 mmHg 4.83 8.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15152 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 35.58 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15155 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 15.62 mmHg 4.45 11.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15153 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 25.75 mmHg 4.11 7.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15160 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 385.8 beats/min 12.46 30.51 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15198 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 108.26 mmHg 6.69 14.95 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15203 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 20.41 mmHg 3.97 9.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15540 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 133.44 mmHg 3.43 8.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15546 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 131.2 mmHg 2.53 8.39 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15547 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 129.33 mmHg 4.8 12.71 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15552 381
F344/DuCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 511.78 beats/min 9.07 23.98 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15785 381
F344/DuCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 505.01 beats/min 12.58 39.79 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15790 381
Crl:CD(SD) mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 120.64 mmHg 1.65 4.68 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15795 381
F344/DuCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 115.14 mmHg 6.64 22.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15801 381
FHH-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 421.37 beats/min 8.75 33.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15902 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 422.85 beats/min 10.01 30.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15908 381
SS-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 432.59 beats/min 1.7 3.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15914 381
FHH-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 388.44 beats/min 20.8 50.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15918 381
SS-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 514.91 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15919 381
SS-Chr 5BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 447.59 beats/min 66.24 93.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15921 381
FHH-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 439.14 beats/min 13.69 33.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15922 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 413.63 beats/min 10.58 36.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15925 381
FHH/EurMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 354.94 beats/min 7.82 20.69 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15342 381
SS-Chr 2BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 123.29 mmHg 4.45 15.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14378 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 114.82 mmHg 3.61 8.07 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14412 381
FHH/EurMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 134.35 mmHg 4.77 13.5 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14411 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 161.85 mmHg 3.08 8.15 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14417 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 122.43 mmHg 4.51 9.02 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14658 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 128.36 mmHg 3.37 8.24 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14660 381
SHR/NCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 129.72 mmHg 6.02 14.74 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14664 381
BN/NHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 99.09 mmHg 1.82 3.63 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14668 381
BN/NHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 95.6 mmHg 4.17 11.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14669 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 122.02 mmHg 7.52 22.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14670 381
FHH-Chr 12BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 369.98 beats/min 6.96 26.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14672 381
SS-Chr 6BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 393.56 beats/min 7.56 25.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14676 381
SS-Chr 9BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 365.71 beats/min 7.38 23.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14677 381
SS-Chr 9BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 438.19 beats/min 12.45 39.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14680 381
SS-Chr 14BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 358.13 beats/min 8.61 25.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14679 381
FHH-Chr 12BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 330.03 beats/min 14.67 46.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14682 381
SS-Chr 10BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 435.22 beats/min 11.58 30.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14683 381
SS-Chr 6BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 360.65 beats/min 7.27 22.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14681 381
FHH-Chr 17BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 398.39 beats/min 12.64 30.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14692 381
FHH-Chr 19BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 405.47 beats/min 22.29 49.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14705 381
SS-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 354.7 beats/min 10.06 30.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14706 381
FHH-Chr 20BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 377.63 beats/min 28.57 63.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14710 381
FHH-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 442.94 beats/min 20.42 45.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15940 381
SS-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 446.88 beats/min 8.86 21.7 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15947 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 460.69 beats/min 54.79 197.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15948 381
SS-Chr 4BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 450.64 beats/min 24.74 60.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15957 381
FHH-Chr 1BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 411.96 beats/min 20.16 57.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15955 381
SS-Chr 19BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 438.72 beats/min 31.16 53.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15961 381
FHH-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 466.66 beats/min 34.17 59.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15963 381
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 0.83 beats/min 10.48 31.44 vascular fluid filled catheter 51681 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 -45.26 beats/min 9.09 37.49 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51691 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 -61.58 beats/min 12.05 48.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51704 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -115.34 beats/min 17.44 42.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51707 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -0.11 beats/min 13.34 40.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51706 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 15.64 mmHg 2.38 5.84 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51735 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 118.02 mmHg 3.47 8.5 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51741 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 22.54 mmHg 3.92 10.38 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51739 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 25.49 mmHg 4.78 12.64 vascular fluid filled catheter 51763 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 17.03 mmHg 2.14 4.79 vascular fluid filled catheter 51764 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 24.22 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51771 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 29.89 mmHg 2.83 9.8 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51774 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 352.38 beats/min 10.21 20.42 vascular fluid filled catheter 51782 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 21.82 mmHg 4.54 12.02 vascular fluid filled catheter 51784 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 14 108.56 mmHg 1.93 7.23 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51789 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 14.65 beats/min 53.53 107.05 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51791 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 129.19 mmHg 3.08 7.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51822 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 112.16 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51830 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 -5.13 beats/min 7.08 29.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51848 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -16.0 beats/min 15.69 54.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51854 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -7.05 beats/min 10.76 21.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51858 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 24.92 mmHg 2.29 8.57 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51860 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 3.0 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51866 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 6.46 mmHg 2.32 6.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51863 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 18.85 mmHg 1.94 8.25 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51864 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 7.1 mmHg 2.79 8.38 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51872 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 118.69 mmHg 1.08 3.25 vascular fluid filled catheter 51877 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 14.07 mmHg 1.28 3.13 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51911 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -16.4 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51922 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 8.94 mmHg 2.68 5.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51971 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 5.12 beats/min 20.66 46.2 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51981 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -61.73 beats/min 11.0 24.59 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51988 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 0.66 mmHg 4.15 10.16 vascular fluid filled catheter 51995 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 1.65 mmHg 2.61 7.83 vascular fluid filled catheter 51994 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 131.99 mmHg 3.79 14.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51997 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 181.05 mmHg 7.86 22.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52003 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 348.29 beats/min 5.0 15.01 vascular fluid filled catheter 52031 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -11.05 beats/min 21.23 60.05 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52048 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -19.59 beats/min 24.09 63.74 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 52070 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -25.42 beats/min 8.98 26.95 vascular fluid filled catheter 52076 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 2.86 beats/min 18.13 47.96 vascular fluid filled catheter 52077 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 129.82 mmHg 3.64 10.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52082 481
SS-Chr 6BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 160.76 mmHg 6.88 20.63 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52832 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 10 190.68 mmHg 5.29 16.74 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52830 482
SS-Chr 7BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 10 143.49 mmHg 2.4 7.59 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52843 482
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 147.43 mmHg 7.77 20.57 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52853 482
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 17 143.21 mmHg 1.44 5.93 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52851 482
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 159.66 mmHg 5.64 14.91 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52847 482
SS-Chr 3BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 5 175.0 mmHg 4.7 10.52 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52852 482
SS-Chr 1BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 14 130.52 mmHg 1.16 4.35 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52860 482
SS-Chr 1BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 19 130.7 mmHg 1.82 7.95 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52863 482
SS-Chr 4BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 7 162.15 mmHg 3.42 9.05 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52870 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 11 145.19 mmHg 3.86 12.8 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52866 482
SS-Chr 19BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 5 151.04 mmHg 12.97 29.0 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52867 482
FHH-Chr 12BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 11 435.43 beats/min 9.42 31.23 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52484 482
FHH-Chr 8BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 8 429.9 beats/min 7.77 21.99 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52486 482
FHH-Chr 14BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 6 424.87 beats/min 7.24 17.73 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52492 482
FHH-Chr 6BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 7 427.27 beats/min 8.16 21.58 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52495 482
FHH-Chr 6BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 411.53 beats/min 7.04 21.12 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52493 482
FHH-Chr 8BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 3 404.67 beats/min 22.74 39.39 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52497 482
FHH-Chr 3BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 4 369.39 beats/min 27.99 55.99 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52507 482
FHH-Chr 2BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 5 433.8 beats/min 7.27 16.25 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52510 482
FHH-Chr 10BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 7 443.07 beats/min 4.2 11.1 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52511 482
FHH-Chr XBN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 6 439.93 beats/min 6.1 14.94 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52519 482
BN/NHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 8 394.19 beats/min 16.08 45.49 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52525 482
FHH-Chr 3BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 2 198.41 mmHg 7.67 10.85 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52536 482
FHH-Chr 13BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 10 188.54 mmHg 5.26 16.64 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52547 482
FHH-Chr YBN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 4 164.84 mmHg 11.34 22.68 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52556 482
FHH-Chr 14BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 8 164.54 mmHg 7.86 22.23 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52555 482
FHH-Chr 2BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 5 182.24 mmHg 14.91 33.34 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52557 482
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 8 187.06 mmHg 10.19 28.82 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52562 482
FHH-Chr 11BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 4 188.98 mmHg 4.83 9.66 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52565 482
FHH-Chr 4BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 165.21 mmHg 10.42 31.27 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52564 482
FHH-Chr 11BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 5 176.89 mmHg 12.96 28.98 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52567 482
FHH-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 8 165.26 mmHg 12.62 35.7 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52576 482
SS-Chr 5BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 8 396.82 beats/min 6.28 17.76 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52644 482
SS-Chr 7BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 10 413.46 beats/min 4.88 15.44 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52645 482
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 371.7 beats/min 9.76 25.82 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52655 482
SS-Chr 11BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 15 401.61 beats/min 7.22 27.95 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52656 482
SS-Chr 1BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 14 411.34 beats/min 5.76 21.55 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52662 482
SS/JrHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 416.02 beats/min 6.59 19.78 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52667 482
SS-Chr 2BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 10 400.36 beats/min 6.22 19.67 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52673 482
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 406.36 beats/min 7.25 29.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50523 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 388.73 beats/min 6.4 20.24 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50527 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 401.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50525 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 451.75 beats/min 12.93 44.79 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50529 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 389.85 beats/min 12.35 34.93 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50530 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 3.0 mmHg 3.86 7.72 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50542 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 1.97 mmHg 2.32 5.68 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50543 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 1.13 beats/min 10.6 23.7 vascular fluid filled catheter 50551 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 410.92 beats/min 6.97 20.92 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50577 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 13.4 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50584 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -93.61 beats/min 7.41 10.48 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50595 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 0.56 mmHg 1.17 3.31 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50599 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 2.06 mmHg 2.57 10.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50600 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 1.29 mmHg 2.0 4.9 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50607 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 3.46 mmHg 3.06 10.59 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50605 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 0.7 mmHg 0.63 1.77 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50610 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -31.24 beats/min 7.66 22.97 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50611 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -0.27 beats/min 11.36 27.82 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50616 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -11.11 beats/min 8.75 26.25 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50618 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -42.28 beats/min 12.66 43.87 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50619 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -22.11 beats/min 15.52 43.91 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50621 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 -21.19 mmHg 2.27 6.01 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50625 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 -13.4 mmHg 2.93 9.26 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50630 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 -25.11 mmHg 3.07 8.68 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50631 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 5.59 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50636 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 119.94 mmHg 1.12 3.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50639 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 114.29 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50642 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 10 148.46 mmHg 3.82 12.09 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50646 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 43.7 mmHg 3.55 7.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50652 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 31.4 mmHg 8.7 17.4 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50658 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 45.88 mmHg 2.54 7.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50661 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 39.26 mmHg 3.2 8.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50664 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 34.55 beats/min 25.93 51.86 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50688 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 16 6.61 mmHg 2.25 8.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50695 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 6.91 mmHg 2.02 7.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50699 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 16.18 mmHg 8.6 21.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50705 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 -0.85 mmHg 4.21 11.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50701 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -26.53 beats/min 23.92 67.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50717 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -27.44 beats/min 13.68 36.19 vascular fluid filled catheter 50729 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 2.96 beats/min 36.05 80.61 vascular fluid filled catheter 50730 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -29.03 beats/min 26.41 64.69 vascular fluid filled catheter 50732 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 101.3 mmHg 2.17 6.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50745 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 30.25 mmHg 4.03 12.74 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50753 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 32.91 mmHg 5.6 13.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50752 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 41.52 mmHg 2.24 6.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50754 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 -5.64 mmHg 2.48 5.55 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50764 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 24.53 mmHg 3.8 11.4 vascular fluid filled catheter 50768 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 -1.39 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50776 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 41.13 mmHg 2.27 5.57 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50784 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 13 -11.14 mmHg 2.22 8.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50802 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 -15.47 mmHg 6.08 14.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50806 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 14 -8.84 mmHg 1.27 4.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50808 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 0.2 mmHg 1.98 5.25 vascular fluid filled catheter 50829 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -99.06 beats/min 19.83 52.45 vascular fluid filled catheter 50832 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 97.54 mmHg 1.66 3.71 vascular fluid filled catheter 50837 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 2.05 mmHg 3.85 9.42 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50842 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 19 1.48 beats/min 8.32 36.25 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50851 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 407.31 beats/min 7.86 23.58 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50856 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 409.47 beats/min 5.64 16.91 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50854 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 385.1 beats/min 13.34 32.69 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50862 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 -76.42 beats/min 10.6 21.21 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50867 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 13 440.55 beats/min 8.86 31.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50879 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 409.57 beats/min 5.76 12.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50881 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 375.46 beats/min 8.18 18.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50889 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 26.0 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50894 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 5.44 beats/min 14.96 29.92 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50891 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 28.03 mmHg 6.24 13.95 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50901 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 4.05 beats/min 12.42 32.85 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50909 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 4.58 beats/min 3.9 9.56 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50910 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 7.16 mmHg 5.12 13.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50919 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 2.79 mmHg 5.37 13.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50922 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 31.89 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50931 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 2.23 mmHg 1.67 4.71 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50937 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 3.95 mmHg 4.82 9.64 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50936 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 165.57 mmHg 8.37 16.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50944 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 136.07 mmHg 3.1 11.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50943 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 110.47 mmHg 3.23 9.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50951 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 -18.72 beats/min 14.13 28.25 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50954 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 432.3 beats/min 3.92 10.36 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50957 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -5.6 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50955 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 16 24.54 mmHg 2.93 11.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50961 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 41.09 mmHg 3.71 9.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50968 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 31.33 mmHg 3.72 9.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50972 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 7.64 beats/min 18.08 36.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50976 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 33.35 mmHg 3.43 9.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50973 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 13 25.74 beats/min 10.93 39.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50978 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 14 10.17 beats/min 8.23 30.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50984 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -28.94 beats/min 6.27 14.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50988 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 8.59 mmHg 3.45 8.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50990 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 -5.24 beats/min 10.35 20.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50989 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 4.37 mmHg 1.82 5.15 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50995 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 5.65 mmHg 3.11 8.22 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50994 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 -2.5 mmHg 2.9 7.67 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50997 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 13.43 mmHg 1.98 5.23 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50998 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 2.47 mmHg 5.7 17.11 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51025 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 11.35 mmHg 4.55 12.87 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51027 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -20.57 beats/min 11.12 29.43 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51037 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -15.09 beats/min 14.75 39.03 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51036 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 -2.18 mmHg 2.36 5.28 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51067 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 -5.94 mmHg 2.7 8.1 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51068 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 2 16.6 beats/min 1.0 1.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51075 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -4.01 beats/min 12.94 31.69 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51089 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 -17.17 beats/min 7.62 32.34 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51088 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 3 -11.61 beats/min 15.08 26.12 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51098 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 9.74 mmHg 1.98 6.85 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51104 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 5.27 mmHg 1.01 3.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51106 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 8.62 mmHg 1.62 4.27 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51107 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 6.71 mmHg 3.2 7.84 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51108 481
SS-Chr 6BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 121.0 mmHg 3.86 12.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14313 381
SS-Chr 7BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 107.76 mmHg 3.41 10.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14318 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 136.03 mmHg 9.09 27.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14320 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 130.98 mmHg 6.21 18.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14329 381
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 145.88 mmHg 5.94 11.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14337 381
SS-Chr 3BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 127.74 mmHg 7.4 16.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14336 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 123.08 mmHg 3.41 9.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14346 381
SS-Chr 11BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 127.9 mmHg 8.01 21.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14350 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 127.52 mmHg 2.78 8.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14349 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 112.35 mmHg 5.55 20.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14355 381
SS-Chr XBN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 119.05 mmHg 10.26 25.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14357 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 15 121.71 mmHg 4.05 15.7 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14358 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 126.72 mmHg 7.24 19.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14367 381
WKY/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 166.8 beats/min 19.28 43.1 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17290 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 127.72 mmHg 7.58 20.05 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13774 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 161.07 mmHg 11.33 22.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13775 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 508.54 beats/min 11.71 46.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13786 381
SS-Chr 20BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 504.44 beats/min 9.04 31.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13785 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 496.55 beats/min 11.45 25.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13790 381
SS-Chr 13BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 446.53 beats/min 11.09 29.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13797 381
FHH-Chr 1BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 495.06 beats/min 14.24 40.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13801 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 522.7 beats/min 7.28 21.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13805 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 514.67 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13807 381
SS-Chr 7BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 504.15 beats/min 13.27 44.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13809 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 482.26 beats/min 17.1 41.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13806 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 464.29 beats/min 9.4 33.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13813 381
SS-Chr 2BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 494.15 beats/min 12.46 37.38 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13816 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 446.53 beats/min 77.6 155.19 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13826 381
Hsd:SD mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 110.44 mmHg 2.77 7.34 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 13824 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 495.78 beats/min 18.91 26.74 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13831 381
WKY/NCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 14 110.54 mmHg 7.28 27.25 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13875 381
LE/BluGill mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 94.47 mmHg 7.0 21.0 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13881 381
Crl:CD(SD) mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 109.25 mmHg 8.69 26.06 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13880 381
WKY/NCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 115.69 mmHg 3.79 14.69 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13883 381
SHR/NCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 140.42 mmHg 5.26 12.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13890 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 104.65 mmHg 2.31 4.62 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13900 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 157.54 mmHg 6.5 15.93 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13907 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 547.29 beats/min 12.81 31.37 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14066 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 510.35 beats/min 25.83 51.66 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14073 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 145.33 beats/min vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14101 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 151.65 beats/min 19.09 26.99 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14106 381
Hsd:SD absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 75.52 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14110 381
WKY/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 108.95 beats/min 10.41 32.92 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14117 381
LEW/Crl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 14 97.88 beats/min 9.62 36.0 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14116 381
FHH/EurMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 114.04 mmHg 3.92 6.79 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14125 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 502.35 beats/min vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19932 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 547.4 beats/min 15.89 27.52 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19934 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 537.8 beats/min 15.76 22.29 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19937 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 507.21 beats/min 8.99 23.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19956 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 519.72 beats/min 10.53 33.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19966 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 468.56 beats/min 15.05 26.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19968 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 457.78 beats/min 39.53 68.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19969 381
SS-Chr 6BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 108.11 mmHg 2.21 8.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20039 381
SS-Chr 9BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 113.94 mmHg 4.01 12.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20044 381
SS-Chr YBN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 16 120.73 mmHg 1.48 5.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20049 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 118.6 mmHg 6.44 18.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20052 381
Crl:CD(SD) absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 9.3 mmHg 3.57 8.75 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20105 381
LEW/Crl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 17 109.76 mmHg 3.64 15.0 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20131 381
LE/BluGill mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 118.44 mmHg 1.42 4.25 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20139 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 105.34 mmHg 2.06 4.12 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19522 381
LEW/Crl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 349.18 beats/min 9.96 39.85 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19544 381
F344/DuCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 405.3 beats/min 10.77 35.73 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19546 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 120.14 mmHg 6.26 12.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19703 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 473.71 beats/min 17.29 29.95 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17668 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 48 409.84 beats/min 3.74 25.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17743 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 425.24 beats/min 8.65 31.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17742 381
GH/OmrMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 439.55 beats/min 6.28 15.38 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17746 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 406.98 beats/min 8.8 26.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17751 381
BN/NHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 17 408.4 beats/min 9.15 37.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17757 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 147.68 mmHg 8.65 17.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17766 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 130.87 mmHg 6.42 16.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17772 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 134.77 mmHg 10.16 32.12 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17775 381
SS-Chr 9BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 126.58 mmHg 5.65 9.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17774 381
Hsd:SD absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 112.66 beats/min 38.45 94.19 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 17965 381
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 8.96 mmHg 2.29 4.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51110 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 394.2 beats/min 10.18 35.26 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51117 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 432.28 beats/min 13.8 41.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51122 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -3.2 mmHg 2.21 5.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51133 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 4.02 mmHg 2.34 9.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51129 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 -6.04 mmHg 3.13 4.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51130 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 6.51 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51131 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 134.29 mmHg 4.87 12.9 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51142 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 145.23 mmHg 3.65 10.96 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51146 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 174.11 mmHg 1.8 5.09 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51148 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -18.33 beats/min 13.72 33.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51164 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 17.74 mmHg 4.17 11.04 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51168 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 14.0 mmHg 3.08 8.14 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51170 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 10.04 mmHg 3.19 9.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51186 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 10.81 mmHg 3.74 9.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51190 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 18.33 mmHg 3.71 10.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51196 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -34.31 beats/min 15.69 47.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51197 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 10.97 beats/min 9.95 24.37 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51202 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -2.44 beats/min 16.86 50.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51204 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -18.95 beats/min 21.78 61.6 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51208 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -18.16 beats/min 10.99 29.07 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51215 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -9.45 beats/min 15.69 44.36 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51216 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -87.08 beats/min 15.51 58.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51222 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -41.4 beats/min 18.42 45.12 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51228 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -5.9 beats/min 15.92 38.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51237 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 390.2 beats/min 8.98 21.99 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51246 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 1.45 beats/min 8.08 24.25 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51261 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 417.6 beats/min 6.66 25.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51281 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 421.83 beats/min 9.17 22.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51283 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 10 368.99 beats/min 4.04 12.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51288 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 356.09 beats/min 6.92 16.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51290 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -13.16 beats/min 18.71 41.84 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51306 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -0.79 beats/min 13.38 29.91 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51307 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -9.38 beats/min 20.13 45.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51330 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 23.11 mmHg 4.68 13.24 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51343 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 -26.39 beats/min 10.75 42.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51349 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -5.36 beats/min 26.01 58.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51348 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -28.67 beats/min 20.76 50.86 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51356 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -27.23 beats/min 16.32 39.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51359 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -19.96 beats/min 18.9 50.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51360 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 2.17 beats/min 10.28 29.07 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51367 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -9.47 beats/min 6.99 20.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51366 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -10.48 beats/min 3.86 8.63 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51369 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 394.09 beats/min 7.89 17.63 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51379 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 101.06 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51393 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 103.26 mmHg 5.16 10.33 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51392 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 1.07 mmHg 3.41 10.22 vascular fluid filled catheter 51394 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -68.33 beats/min 19.97 48.92 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51404 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -28.4 beats/min 24.13 59.1 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51406 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -109.6 beats/min 11.6 16.4 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51407 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -40.01 beats/min 11.6 25.94 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51409 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 16.77 mmHg 3.57 9.46 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51417 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 47.8 mmHg 3.54 7.93 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51420 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 45.65 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51423 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 31.81 mmHg 3.63 12.58 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51427 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 30.72 mmHg 3.16 8.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51429 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 43.38 mmHg 2.58 7.74 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51432 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 386.26 beats/min 6.07 14.87 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51481 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 32.17 mmHg 4.7 13.29 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51493 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 3 9.52 mmHg 0.72 1.24 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51495 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 7.05 mmHg 1.68 4.12 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51496 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -12.36 beats/min 24.22 54.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51502 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -28.06 beats/min 17.7 46.83 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51504 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 2 4.98 mmHg 2.37 3.35 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51500 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -4.67 beats/min 11.92 29.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51506 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -46.0 beats/min 14.52 50.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51509 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -38.7 beats/min 18.21 36.42 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51513 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -16.97 beats/min 11.37 25.42 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51529 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 20 -8.4 beats/min 8.54 38.19 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51573 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 364.17 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51587 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -0.4 mmHg 1.94 5.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51592 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 4.01 mmHg 3.18 8.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51600 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 2 115.6 beats/min 48.0 67.88 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51613 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -74.53 beats/min 10.32 23.07 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51612 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 1.15 mmHg 3.77 9.97 vascular fluid filled catheter 51625 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 160.02 mmHg 8.89 23.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51634 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 107.88 mmHg 3.52 7.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51637 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 103.82 mmHg 2.35 6.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51638 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 4.2 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51658 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 25.5 mmHg 3.34 10.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51657 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 0.48 mmHg 1.96 4.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51663 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 31.19 mmHg 2.1 4.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51667 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 26.33 mmHg 3.02 7.4 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51668 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 4.15 beats/min 23.97 47.94 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51673 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 392.51 beats/min 6.61 25.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50326 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 389.05 beats/min 11.35 32.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50330 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 358.8 beats/min 16.08 39.38 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50332 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 3.42 mmHg 1.85 4.89 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50342 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -71.27 beats/min 21.14 42.27 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50344 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -45.24 beats/min 26.63 70.44 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50347 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 109.1 mmHg 3.86 10.21 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50351 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 -45.27 beats/min 22.01 44.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50363 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 7.53 mmHg 1.09 2.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50365 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 6.33 mmHg 2.64 6.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50369 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 4.74 mmHg 3.69 9.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50376 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 11.73 mmHg 3.99 10.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50377 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 14.83 mmHg 3.29 12.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50375 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 4.25 mmHg 3.78 8.46 vascular fluid filled catheter 50380 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 2.93 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50386 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 4.13 mmHg 3.85 8.62 vascular fluid filled catheter 50406 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -41.3 beats/min 29.44 88.33 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50427 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -3.15 beats/min 20.75 41.49 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50428 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 -0.2 mmHg 4.63 12.24 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50434 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 0.91 mmHg 0.26 0.36 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50433 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 379.43 beats/min 10.59 23.67 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50449 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 404.68 beats/min 23.22 56.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50474 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 398.32 beats/min 8.71 32.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50475 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 402.34 beats/min 10.96 30.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50483 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 3.03 mmHg 1.25 4.68 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50500 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -4.08 beats/min 19.02 42.54 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50505 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 31.47 beats/min 18.3 44.84 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50511 481
SS-Chr 5BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 368.73 beats/min 6.96 18.42 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52646 482
FHH-Chr 18BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 398.65 beats/min 21.36 52.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14716 381
SS-Chr 11BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 419.52 beats/min 14.53 35.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14717 381
SS-Chr 11BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 450.49 beats/min 23.65 52.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14721 381
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 411.25 beats/min 8.66 27.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14728 381
FHH-Chr 11BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 399.38 beats/min 36.3 62.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14733 381
BN/NHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 239.74 beats/min 14.05 44.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14740 381
SS.BN-(D13Rat57-D13Rat192)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 181.0 mmHg 2.7 9.35 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5402 15
SS.BN-(D13Rat57-D13Rat192)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 173.0 mmHg 3.7 12.82 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5401 15
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 heart rate during walking-heart rate during rest 90.48 beats/min 9.72 38.87 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13383 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 heart rate during walking-heart rate during rest 64.71 beats/min 19.85 48.63 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13384 381
SS-Chr YBN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 heart rate during walking-heart rate during rest 69.33 beats/min 9.08 28.7 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13395 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 heart rate during walking-heart rate during rest 91.91 beats/min 11.62 32.87 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13405 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 heart rate during walking-heart rate during rest 63.87 beats/min 12.33 47.75 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13411 381
FHH-Chr 1BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 heart rate during walking-heart rate during rest 60.15 beats/min 13.17 45.61 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13412 381
Hsd:SD mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 118.12 mmHg 6.17 10.69 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13449 381
WKY/NCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 125.14 mmHg 6.06 16.03 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13456 381
LE/BluGill mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 125.06 mmHg 2.7 7.64 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13458 381
SS-Chr 10BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 113.16 mmHg 2.72 8.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13460 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 14 129.83 mmHg 2.9 10.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13461 381
SS-Chr 6BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 105.6 mmHg 2.51 8.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13463 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 126.23 mmHg 6.6 16.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13475 381
SS-Chr 17BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 101.75 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13476 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 122.43 mmHg 5.96 14.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13479 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 135.7 mmHg 10.29 25.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13486 381
SS-Chr 15BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 126.84 mmHg 7.95 11.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13491 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 113.14 mmHg 8.07 18.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13497 381
SS-Chr 11BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 117.84 mmHg 4.44 9.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13508 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 123.56 mmHg 5.3 15.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13517 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 121.05 mmHg 3.21 9.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14304 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 124.43 mmHg 3.67 10.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14309 381
FHH-Chr 6BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 80.22 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14310 381
SHRSP.WKY-(D2Wox9-D2Mgh12)/Gcrc systolic blood pressure control condition Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 91.0 days-126.0 days 12 173.1 mmHg 4.66 16.14 vascular fluid filled catheter abdominal aorta 3024000 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 35 days 12734 302
SHR/N systolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait female 84.0 days 16 163.0 mmHg 12.0 48.0 vascular fluid filled catheter right carotid 13051 327
WKY/N diastolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait female 84.0 days 22 103.0 mmHg 9.0 42.21 vascular fluid filled catheter right carotid 13068 327
WKY/N systolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait female 84.0 days 22 130.0 mmHg 5.0 23.45 vascular fluid filled catheter right carotid 13067 327
SS/Jr mean arterial blood pressure controlled sodium content diet (8 %) (between 21 and 25 days) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. arterial blood pressure trait male 82.0 days-86.0 days 69 serial mean 187.0 mmHg vascular fluid filled catheter femoral artery 345600 connected to solid-state transducer (Argon Medical Technologies, Athens, TX) 5 hr recording session - 1 min. averages, averaged over 4 days 12613 272
SS.LEW-(D5Rat130-D5Rat31)/JrMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 21 and 25 days) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. arterial blood pressure trait male 82.0 days-86.0 days 32 serial mean 159.0 mmHg vascular fluid filled catheter femoral artery 345600 connected to solid-state transducer (Argon Medical Technologies, Athens, TX) 5 hr recording session - 1 min. averages, averaged over 4 days 12618 272
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 129.42 mmHg 1.67 4.73 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19706 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 169.46 mmHg 5.07 10.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19714 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 133.2 mmHg 6.56 17.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19713 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 122.64 mmHg 1.51 4.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19846 381
SS-Chr 14BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 123.72 mmHg 2.94 8.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19847 381
SS-Chr 9BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 112.55 mmHg 3.24 10.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19848 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 158.22 mmHg 5.73 14.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19855 381
SS-Chr 10BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 112.53 mmHg 3.92 10.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19851 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 119.91 mmHg 4.57 9.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19853 381
SS-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 95.11 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19857 381
SS-Chr 15BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 133.32 mmHg 6.53 9.23 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19872 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 125.5 mmHg 3.88 10.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19875 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 118.88 mmHg 7.24 16.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19878 381
SS-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 112.35 mmHg 7.87 17.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19889 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 122.4 mmHg 1.96 6.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19886 381
SS-Chr 19BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 113.81 mmHg 10.33 17.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19899 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 16 10.57 mmHg 1.18 4.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20714 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 11.68 mmHg 5.52 13.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20715 381
SS-Chr 13BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 13.36 mmHg 2.76 8.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20721 381
SS-Chr YBN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 14.02 mmHg 2.07 6.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20727 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 10.89 mmHg 0.64 0.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20725 381
SS-Chr 13BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 19.8 mmHg 2.02 5.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20726 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 7.74 mmHg 2.69 9.7 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20728 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 24.83 mmHg 3.33 9.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20737 381
Hsd:SD mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 109.47 mmHg 3.65 11.54 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 20846 381
FHH-Chr 6BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 349.63 beats/min 7.67 10.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20896 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 400.41 beats/min 5.58 18.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20895 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 434.16 beats/min 9.9 28.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20900 381
SS-Chr 10BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 403.0 beats/min 14.77 44.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20906 381
SS-Chr 9BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 448.34 beats/min 16.91 56.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20903 381
SS-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 428.62 beats/min 9.21 26.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20907 381
FHH-Chr 17BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 389.45 beats/min 21.49 64.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20911 381
SS-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 449.19 beats/min 18.96 56.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20917 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 414.25 beats/min 11.44 37.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20924 381
SS-Chr 15BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 441.91 beats/min 27.7 55.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20928 381
FHH-Chr 1BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 15 450.47 beats/min 8.58 33.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20949 381
SS-Chr 19BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 421.0 beats/min 23.94 47.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20956 381
FHH-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 443.8 beats/min 43.16 74.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20961 381
SS-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 445.35 beats/min 45.54 78.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20964 381
FHH-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 415.85 beats/min 9.86 17.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20968 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 264.71 beats/min 13.8 49.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20965 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 14 318.41 beats/min 11.5 43.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20966 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 122.01 mmHg 14.72 20.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19903 381
Hsd:SD heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 348.49 beats/min 13.28 23.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18079 381
Crl:CD(SD) heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 336.8 beats/min 15.61 44.15 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18083 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 408.74 beats/min 22.8 60.31 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18103 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 441.62 beats/min 9.52 25.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18105 381
SS.BN-(D13Rat7-D13Rat88)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 161.0 mmHg 3.7 12.82 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65160 15
SS-Chr 9BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 100.29 beats/min 10.9 28.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18357 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 148.65 beats/min 13.67 23.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18359 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 62.48 beats/min 17.33 42.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18361 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 463.94 beats/min 9.59 19.19 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18758 381
Hsd:SD mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 126.43 mmHg 0.43 0.6 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18763 381
F344/DuCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 106.63 mmHg 2.22 6.28 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18766 381
LE/BluGill mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 102.7 mmHg 3.35 8.86 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18768 381
LE/BluGill mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 117.19 mmHg 3.31 8.75 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18772 381
WKY/NCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 97.22 mmHg 3.09 9.78 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18781 381
SS-Chr 20BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 120.53 mmHg 4.34 15.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18928 381
SS-Chr YBN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 136.73 mmHg 2.58 8.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18942 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 121.58 mmHg 3.23 7.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18948 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 130.24 mmHg 5.5 16.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18952 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 132.75 mmHg 9.71 30.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18954 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 117.61 mmHg 3.76 8.4 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19007 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 115.6 mmHg 10.41 18.04 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19009 381
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 17 411.57 beats/min 13.0 53.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17475 381
SS-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 356.59 beats/min 14.44 28.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17494 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 429.6 beats/min 6.58 13.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17498 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 420.82 beats/min 18.01 59.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17506 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 441.23 beats/min 11.82 40.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17507 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 418.72 beats/min 12.0 36.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17512 381
SS-Chr 3BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 400.21 beats/min 26.78 59.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17509 381
FHH-Chr 8BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 395.92 beats/min 8.61 21.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17514 381
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 368.52 beats/min 21.37 56.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17520 381
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 388.29 beats/min 19.22 54.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17519 381
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 380.7 beats/min 11.99 37.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17518 381
SS-Chr YBN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 18 413.66 beats/min 11.85 50.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17526 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 399.04 beats/min 15.76 56.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17528 381
FHH-Chr 1BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 15 425.56 beats/min 14.49 56.12 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17531 381
FHH-Chr 4BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 392.32 beats/min 63.41 89.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17535 381
FHH-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 771.68 beats/min 175.59 430.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17536 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 399.04 beats/min 8.58 30.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17545 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 273.08 beats/min 29.68 93.86 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17548 381
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 446.64 beats/min 26.84 53.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17546 381
Hsd:SD heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 501.86 beats/min 8.02 24.05 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 17554 381
SS-Chr 2BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 451.08 beats/min 16.57 57.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17551 381
Hsd:SD heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 463.63 beats/min 13.32 35.23 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 17553 381
SS.BN-(D13Hmgc64-RN34_13048990782)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 171.0 mmHg 3.8 13.16 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65170 15
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 127.2 mmHg 2.95 8.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19516 381
SS.BN-(D13Rat115-D13Rat61)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 166.0 mmHg 3.0 10.39 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65173 15
SS.BN-(D13Rat91-D13Rat179)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 185.0 mmHg 2.7 9.35 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65178 15
SS.BN-(D13Rat127-D13Rat77)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 175.0 mmHg 4.4 15.24 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65182 15
SS.BN-(D13Rat127-D13Rat46)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 154.0 mmHg 3.1 10.74 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65188 15
SS.BN-(D13Got51-D13Rat57)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 169.0 mmHg 2.5 8.66 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65195 15
SS.BN-(D13Rat151-D13Rat197)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 172.0 mmHg 3.6 12.47 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65198 15
SS-Chr 16BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 444.88 beats/min 12.64 35.75 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18196 381
SHR/NCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 393.41 beats/min 4.55 10.18 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18204 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 94.0 mmHg 4.35 11.52 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20398 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 105.4 mmHg 9.2 15.93 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20401 381
SHR/NCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 133.97 mmHg 5.35 11.96 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20404 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 82.61 beats/min 9.27 27.8 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20422 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 464.22 beats/min 19.14 46.88 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20433 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 418.62 beats/min 17.4 52.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20440 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 564.79 beats/min 7.24 20.48 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20528 381
Hsd:SD mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 116.49 mmHg 5.67 22.69 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 16118 381
LE/BluGill heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 376.9 beats/min 12.54 37.63 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16131 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 453.45 beats/min 16.75 47.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16353 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 435.09 beats/min 6.64 17.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16354 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 447.76 beats/min 12.54 37.63 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16360 381
F344/DuCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 434.78 beats/min 13.95 46.26 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16431 381
Crl:CD(SD) heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 419.01 beats/min 16.51 40.43 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16430 381
WKY/NCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 396.39 beats/min 7.63 24.12 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16435 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 6.1 mmHg 2.26 6.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16777 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 10.88 mmHg 3.92 10.38 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16779 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 14.73 mmHg 7.71 13.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16782 381
SS/NEisSlc mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 8 146.0 mmHg 6.0 16.97 vascular fluid filled catheter 0.0 102365 2687
SS/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female  days 132.0 mmHg 2.0 vascular fluid filled catheter 0.0 102212 2681
Crl:WI(WU) mean arterial blood pressure sham surgical control condition Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 14 105.0 mmHg 5.0 18.71 vascular fluid filled catheter 0.0 sham surgery 35 days 100013 2398
Crl:WI(WU) mean arterial blood pressure thoracic aorta constriction Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 8 111.0 mmHg 13.0 36.77 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100023 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then quinapril (2 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 11 98.0 mmHg 5.0 16.58 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100024 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then losartan (3 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 14 104.0 mmHg 6.0 22.45 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100026 2398
SD-Nfe2l2em1Mcwi+/+ mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 70 and 84 days) then controlled sodium chloride content diet (4 %) (for 3 days) then angiotensin II (100 ng/kg/min) (for 3 days) Priestley JR, et al., Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H478-87. doi: 10.1152/ajpheart.00586.2015. Epub 2015 Dec 4. arterial blood pressure trait male 62.0 days-76.0 days 3 95.0 mmHg 4.3 7.45 vascular fluid filled catheter 0.0 100741 2520
SD-Nfe2l2em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 70 and 84 days) then controlled sodium chloride content diet (4 %) (for 3 days) then 0.9% sodium chloride solution (for 3 days) Priestley JR, et al., Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H478-87. doi: 10.1152/ajpheart.00586.2015. Epub 2015 Dec 4. arterial blood pressure trait male 62.0 days-76.0 days 3 102.0 mmHg 3.0 5.2 vascular fluid filled catheter 0.0 100740 2520
LH/Mav mean arterial blood pressure right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 350.0 days 7 148.0 mmHg 5.0 13.23 vascular fluid filled catheter 0.0 104575 2970
MHS mean arterial blood pressure streptozotocin (55 ml/kg) then insulin (4 IU/kg) (for 168 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 252.0 days 6 139.8 mmHg 1.84 4.5 vascular fluid filled catheter trunk of common carotid artery 0.0 104109 2907
SS/JrHsdMcwi mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 70 days) Rudemiller NP, et al., Hypertension. 2015 May;65(5):1111-7. doi: 10.1161/HYPERTENSIONAHA.114.04736. Epub 2015 Mar 16. arterial blood pressure trait not specified 70.0 days 6 15sec/min for 3 hrs/day for 7days 127.5 mmHg 1.5 3.67 vascular fluid filled catheter 0.0 n=6-8 106520 3031
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) then 2% dimethyl sulfoxide in artificial cerebrospinal fluid (300 nl/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 425.0 beats/min 11.0 22.0 vascular fluid filled catheter femoral artery 600.0 106779 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) then kynurenate (0.14 ug/min) (for 0.2 hours) then candesartan (0.5 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 5 410.0 beats/min 15.0 33.54 vascular fluid filled catheter femoral artery 600.0 106784 2685
SS/JrHsdMcwi right ventricular end-systolic blood pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart right ventricular blood pressure trait male 56.0 days 6 26.0 mmHg 0.99 2.42 vascular fluid filled catheter 0.0 106796 3032
SS-Sod3m1Mcwi heart rate vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart pumping trait male 56.0 days 8 354.0 beats/min 12.9 36.49 vascular fluid filled catheter 0.0 106799 3032
SS/JrHsdMcwi systolic blood pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 8 108.0 mmHg 2.62 7.41 vascular fluid filled catheter 0.0 106804 3032
SS-Sod3m1Mcwi systolic blood pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 8 115.0 mmHg 5.22 14.76 vascular fluid filled catheter 0.0 106803 3032
SS-Sod3m1Mcwi mean aortic pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 8 94.5 mmHg 5.02 14.2 vascular fluid filled catheter 0.0 Mean aortic pressure 106811 3032
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 111.0 mmHg 4.0 8.0 vascular fluid filled catheter femoral artery 600.0 106765 2685
SS/HsdMcwiCrl heart rate controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 435.0 beats/min 12.0 24.0 vascular fluid filled catheter femoral artery 600.0 106771 2685
ACI/SegHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 9 116.0 mmHg 5.0 15.0 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107329 3077
SR/Hsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 124.0 mmHg 2.0 6.32 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107335 3077
SS/HsdMcwiCrl mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 8 123.0 mmHg 4.0 11.31 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107336 3077
WKY/NCrl absolute change in mean arterial blood pressure artificial cerebrospinal fluid (200 nl) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait not specified  days 7 2.0 mmHg 1.0 2.65 vascular fluid filled catheter 0.0 110103 2685
WKY/NCrl absolute change in heart rate artificial cerebrospinal fluid (200 nl) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait not specified  days 7 9.0 beats/min 4.0 10.58 vascular fluid filled catheter 0.0 110107 2685
WKY/NCrl absolute change in heart rate artificial cerebrospinal fluid (200 nl) then angiotensin II (90 ng) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait not specified  days 7 29.0 beats/min 6.0 15.87 vascular fluid filled catheter 0.0 110108 2685
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 123.06 mmHg 2.43 8.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15066 381
FHH-Chr 6BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 141.73 mmHg 28.73 40.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15067 381
FHH-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 125.99 mmHg 3.59 11.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15076 381
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 156.71 mmHg 5.9 16.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15084 381
SS-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 120.67 mmHg 2.9 8.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15088 381
FHH-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 135.36 mmHg 7.68 23.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15091 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 118.09 mmHg 3.36 11.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15096 381
SS-Chr 15BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 140.63 mmHg 12.18 24.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15097 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 119.61 mmHg 2.83 8.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15101 381
SS-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 119.15 mmHg 2.18 6.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15107 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 127.33 mmHg 5.58 12.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15105 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 136.28 mmHg 4.32 12.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15106 381
SS-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 133.49 mmHg 3.36 8.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15116 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 119.96 mmHg 2.39 8.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15117 381
SS-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 120.02 mmHg 2.02 5.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15114 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 62 125.01 mmHg 1.69 13.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15118 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 132.9 mmHg 8.84 23.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15129 381
SS-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 117.91 mmHg 14.62 25.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15135 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 11.29 mmHg 4.37 7.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15142 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 17.16 mmHg 1.32 2.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15146 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 22 21.73 mmHg 1.57 7.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15145 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 12.67 mmHg 7.62 15.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15148 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 5.79 mmHg 4.09 12.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15157 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 450.69 beats/min 12.38 24.77 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15197 381
Hsd:SD heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 415.08 beats/min 18.43 61.13 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15520 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 11.9 mmHg 3.34 9.45 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15537 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 32.39 mmHg 5.47 10.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15545 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 118.51 mmHg 2.56 6.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15551 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 102.23 mmHg 1.72 4.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15555 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 129.17 mmHg 2.23 6.69 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15553 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 131.39 mmHg 4.31 12.92 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15556 381
SS-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 456.16 beats/min 13.74 19.42 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15590 381
SS-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 395.18 beats/min 31.95 45.18 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15592 381
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 401.38 beats/min 19.18 38.37 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15594 381
GH/OmrMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 343.55 beats/min 14.22 34.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15595 381
Hsd:SD heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 425.19 beats/min 13.38 53.54 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15756 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 6.2 mmHg 2.15 3.05 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15760 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 18.07 mmHg 3.28 7.34 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15761 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 23.72 mmHg 6.66 14.88 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15764 381
Crl:CD(SD) heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 526.73 beats/min 9.55 25.27 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15786 381
WKY/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 14 121.44 mmHg 5.03 18.81 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15792 381
LEW/Crl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 112.72 mmHg 2.63 10.52 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15794 381
LEW/Crl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 16 104.55 mmHg 3.49 13.94 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15799 381
LE/BluGill mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 103.47 mmHg 6.93 20.78 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15798 381
WKY/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 120.33 mmHg 4.38 16.98 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15800 381
SS-Chr 14BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 407.86 beats/min 8.54 22.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15905 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 14 413.27 beats/min 9.52 35.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15904 381
SS-Chr 9BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 411.45 beats/min 4.58 14.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15907 381
FHH-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 400.83 beats/min 14.89 47.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15912 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 450.17 beats/min 13.07 32.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15917 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 413.01 beats/min 14.97 29.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15923 381
FHH-Chr 8BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 395.68 beats/min 10.88 28.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15927 381
SS-Chr 15BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 464.17 beats/min 22.72 45.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15932 381
SS-Chr 16BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 402.32 beats/min 10.57 25.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15341 381
BN/NHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 283.69 beats/min 2.77 4.81 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15343 381
BN/NHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 337.31 beats/min 24.18 48.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15344 381
SHR/NCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 409.29 beats/min 13.42 32.86 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15346 381
SS/JrHsdMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 418.52 beats/min 9.02 27.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15345 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 120.93 mmHg 6.37 18.01 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14410 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 141.2 mmHg 6.68 17.68 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14413 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 121.94 mmHg 4.78 10.7 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14653 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 114.91 mmHg 1.57 2.21 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14656 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 131.52 mmHg 2.55 8.47 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14661 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 109.6 mmHg 5.05 13.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14665 381
SS-Chr 14BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 397.58 beats/min 10.68 28.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14675 381
GH/OmrMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 412.53 beats/min 9.46 23.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14687 381
SS-Chr 7BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 383.49 beats/min 14.07 37.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14686 381
SHR/NCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 435.5 beats/min 12.38 41.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14695 381
SS-Chr 20BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 13 410.91 beats/min 8.77 31.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14698 381
FHH/EurMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 384.44 beats/min 16.52 46.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14700 381
SS-Chr 3BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 397.67 beats/min 15.63 34.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14703 381
SS-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 456.56 beats/min 10.43 27.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15942 381
FHH-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 420.01 beats/min 15.46 37.86 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15944 381
SS-Chr YBN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 432.09 beats/min 17.32 69.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15950 381
FHH-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 409.46 beats/min 15.5 37.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15946 381
SS-Chr 13BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 429.15 beats/min 16.44 46.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15949 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 50 419.34 beats/min 5.77 40.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15953 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 433.43 beats/min 7.28 23.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15956 381
SS-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 404.36 beats/min 12.26 17.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15962 381
SS-Chr 4BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 439.68 beats/min 18.06 47.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15964 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 294.98 beats/min 22.21 73.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15970 381
FHH-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 418.19 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15972 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 123.19 mmHg 13.56 23.49 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16024 381
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -25.07 beats/min 31.67 77.58 vascular fluid filled catheter 51682 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -61.17 beats/min 13.72 36.3 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51692 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -74.49 beats/min 13.87 48.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51697 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 15.4 beats/min 7.93 19.42 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51694 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -74.95 beats/min 19.95 39.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51701 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -90.84 beats/min 15.38 37.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51711 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -112.51 beats/min 21.22 60.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51716 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -2.4 beats/min 10.64 23.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51717 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -13.09 beats/min 24.31 64.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51729 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -38.48 beats/min 13.18 37.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51730 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 108.62 mmHg 3.76 9.22 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51731 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 115.62 mmHg 3.34 4.72 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51744 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 126.47 mmHg 2.33 6.16 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51745 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 142.57 mmHg 3.01 8.51 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51746 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 16.22 mmHg 3.11 8.81 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51768 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 36.2 mmHg 2.54 6.73 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51775 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 390.89 beats/min 8.33 20.42 vascular fluid filled catheter 51783 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 6.35 mmHg 2.94 6.58 vascular fluid filled catheter 51785 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 114.44 mmHg 1.98 6.87 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51788 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -3.3 beats/min 0.3 0.42 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51793 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 24.8 mmHg 0.3 0.42 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51815 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 28.68 mmHg 3.5 7.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51817 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 3 140.54 mmHg 14.06 24.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51823 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -26.49 beats/min 16.87 44.63 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51849 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 22.21 beats/min 6.03 17.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51855 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 11.12 beats/min 17.12 51.37 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51859 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 25.17 mmHg 2.4 8.32 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51867 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 21.1 mmHg 4.61 11.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51871 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -14.79 mmHg 5.52 16.56 vascular fluid filled catheter 51914 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 -4.69 mmHg 2.7 5.4 vascular fluid filled catheter 51916 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -1.91 mmHg 2.6 6.36 vascular fluid filled catheter 51917 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -27.75 beats/min 7.94 30.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51923 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 6.68 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51962 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 24.43 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51965 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 15.84 mmHg 2.33 8.7 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51968 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -11.7 beats/min 14.89 36.47 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51979 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -36.87 beats/min 22.47 59.45 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51990 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -45.99 beats/min 11.57 30.62 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51991 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 13 124.79 mmHg 2.58 9.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51998 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 13 121.91 mmHg 2.36 8.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52001 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 91.79 mmHg 3.28 6.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52009 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -0.47 mmHg 3.39 10.17 vascular fluid filled catheter 52025 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 91.52 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52051 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 18.29 beats/min 7.47 18.3 vascular fluid filled catheter 52067 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 125.91 mmHg 2.56 3.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52085 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 133.43 mmHg 3.83 10.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52090 481
SS-Chr 10BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 10 171.08 mmHg 6.65 21.04 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52829 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 181.29 mmHg 4.8 14.41 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52834 482
SS-Chr YBN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 15 163.31 mmHg 4.36 16.88 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52857 482
SS-Chr 12BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 162.57 mmHg 8.34 22.07 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52868 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 20 156.0 mmHg 7.15 31.98 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52872 482
LE/BluGill mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 113.88 mmHg 4.03 12.09 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52241 482
FHH-Chr 13BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 8 408.56 beats/min 6.84 19.33 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52498 482
FHH-Chr 5BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 391.88 beats/min 8.41 22.26 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52496 482
FHH-Chr 17BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 8 404.47 beats/min 25.87 73.18 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52515 482
FHH-Chr 17BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 12 433.19 beats/min 8.02 27.79 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52516 482
FHH-Chr 4BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 444.42 beats/min 7.91 23.74 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52517 482
FHH-Chr 10BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 5 406.89 beats/min 10.72 23.98 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52523 482
FHH-Chr 5BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 5 142.41 mmHg 8.36 18.69 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52537 482
FHH-Chr 8BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 3 159.61 mmHg 9.53 16.51 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52544 482
FHH-Chr 15BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 7 132.56 mmHg 2.89 7.65 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52553 482
FHH-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 6 146.31 mmHg 3.71 9.1 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52549 482
FHH-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 8 162.82 mmHg 9.3 26.3 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52551 482
FHH-Chr 10BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 7 172.75 mmHg 3.57 9.43 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52558 482
FHH-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 4 170.24 mmHg 5.85 11.71 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52568 482
FHH-Chr XBN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 5 161.13 mmHg 10.34 23.11 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52573 482
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 8 120.84 mmHg 2.6 7.37 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52571 482
FHH-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 4 174.85 mmHg 7.9 15.81 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52574 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 10 415.28 beats/min 9.27 29.32 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52632 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 427.95 beats/min 12.74 38.22 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52636 482
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 377.57 beats/min 5.93 17.79 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52635 482
SS-Chr 6BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 421.12 beats/min 11.29 33.88 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52634 482
SS-Chr 6BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 10 427.88 beats/min 12.27 38.8 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52639 482
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 8 418.44 beats/min 6.84 19.34 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52638 482
SS-Chr 17BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 404.73 beats/min 7.16 21.49 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52641 482
SS-Chr 15BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 5 403.16 beats/min 14.0 31.31 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52650 482
SS-Chr 11BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 14 378.79 beats/min 10.47 39.16 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52658 482
SS-Chr XBN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 5 432.4 beats/min 14.46 32.33 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52663 482
SS-Chr 4BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 399.08 beats/min 14.32 37.89 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52666 482
SS-Chr 4BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 7 394.95 beats/min 21.66 57.31 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52672 482
SS-Chr 12BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 6 379.27 beats/min 8.81 21.58 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52675 482
SS-Chr 2BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 397.25 beats/min 8.94 26.81 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52679 482
BN/NHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 18 384.5 beats/min 7.1 30.12 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52677 482
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 20.6 beats/min 13.45 26.91 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50513 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -71.1 beats/min 33.5 82.05 vascular fluid filled catheter 50518 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 447.89 beats/min 21.52 56.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50524 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 443.08 beats/min 14.63 43.9 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50534 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 118.22 mmHg 2.65 7.94 vascular fluid filled catheter 50546 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 413.17 beats/min 9.33 28.0 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50579 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -37.31 beats/min 13.25 51.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50582 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -77.5 beats/min 34.7 49.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50583 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -20.32 beats/min 34.38 84.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50586 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -30.8 beats/min 7.68 18.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50591 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 -9.14 beats/min 7.81 32.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50613 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -3.37 beats/min 12.33 34.86 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50620 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 0.28 beats/min 13.27 39.81 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50624 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 10 -17.53 mmHg 2.45 7.75 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50632 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 -2.98 mmHg 0.76 2.39 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50635 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 133.26 mmHg 2.16 5.28 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50641 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 101.04 mmHg 1.9 5.37 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50651 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 24.98 mmHg 4.81 18.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50657 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 444.41 beats/min 19.19 27.14 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50669 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 119.36 mmHg 4.72 11.57 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50672 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 3 118.36 mmHg 3.5 6.07 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50673 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 139.07 mmHg 3.77 9.23 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50674 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 2 142.46 mmHg 8.89 12.57 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50678 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 129.46 mmHg 0.32 0.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50675 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -21.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50682 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -1.47 beats/min 34.5 84.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50684 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -14.23 beats/min 4.03 9.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50689 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 0.61 mmHg 1.97 7.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50704 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 370.4 beats/min 9.67 21.63 vascular fluid filled catheter 50709 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 -40.21 beats/min 9.65 40.92 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50718 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 12 -31.9 beats/min 21.48 74.43 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50721 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 134.45 mmHg 2.41 9.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50735 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 120.15 mmHg 2.48 6.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50737 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 10 169.54 mmHg 5.39 17.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50736 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 10 149.76 mmHg 4.03 12.74 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50742 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 32.74 mmHg 4.09 9.15 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50748 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 29.73 mmHg 2.92 8.76 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50747 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 17 27.75 mmHg 2.45 10.1 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50749 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 39.34 mmHg 4.82 13.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50756 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 -18.8 mmHg 3.71 8.29 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50761 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 -8.98 mmHg 4.38 9.8 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50762 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 2.22 mmHg 2.02 7.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50777 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 3.46 mmHg 1.52 4.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50781 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 4.02 mmHg 8.2 20.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50783 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 40.43 mmHg 1.89 4.23 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50789 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 2 27.32 mmHg 13.75 19.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50790 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 10.07 beats/min 3.47 9.18 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50792 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 126.48 mmHg 5.04 11.27 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50794 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 -2.84 mmHg 7.8 17.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50800 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 112.87 mmHg 3.21 6.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50797 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 -11.35 mmHg 4.78 14.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50803 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 -6.61 mmHg 7.53 21.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50807 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 6.82 mmHg 1.9 4.64 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50817 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 5.25 beats/min 13.2 26.41 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50820 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 0.91 mmHg 2.27 4.55 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50818 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 -0.2 mmHg 2.08 4.16 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50816 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 37.3 mmHg 2.27 8.81 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50827 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 113.96 mmHg 3.81 9.34 vascular fluid filled catheter 50839 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 2 31.74 mmHg 13.43 18.99 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50846 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 18.57 mmHg 3.24 7.24 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50845 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -19.44 beats/min 7.37 28.54 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50852 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 394.6 beats/min 13.13 26.26 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50861 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 383.6 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50864 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 13 395.28 beats/min 9.37 33.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50882 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 14 429.17 beats/min 4.83 18.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50885 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 17.13 beats/min 16.45 32.89 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50893 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 29.29 mmHg 4.91 12.03 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50897 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 34.12 mmHg 1.84 2.6 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50900 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 12.14 beats/min 6.37 16.86 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50906 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 2 23.96 mmHg 20.35 28.78 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50903 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 8.33 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50915 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -3.73 mmHg 1.03 2.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50917 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 5.73 mmHg 2.57 8.9 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50930 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 11.69 mmHg 6.31 15.46 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50934 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 124.78 mmHg 3.22 7.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50949 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 140.39 mmHg 3.51 13.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50948 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 35.98 mmHg 2.91 11.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50962 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 24.17 mmHg 4.29 10.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50964 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 44.15 mmHg 3.53 10.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50969 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 4.64 beats/min 5.39 16.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50979 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 13 8.0 beats/min 11.17 40.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50981 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 14.04 beats/min 6.89 19.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50983 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 37.45 beats/min 19.76 73.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50986 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 5.49 mmHg 2.01 2.84 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50993 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 17 116.23 mmHg 1.62 6.67 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51016 481
Hsd:SD mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 14 111.02 mmHg 1.15 4.31 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51017 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 6.8 mmHg 2.91 6.51 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51019 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 8.14 mmHg 2.01 6.03 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51018 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 10.55 mmHg 3.4 8.34 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51023 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 11.55 mmHg 3.48 9.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51021 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 7.32 mmHg 3.21 6.42 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51030 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 -0.58 mmHg 2.12 5.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51029 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 0.07 beats/min 14.92 39.49 vascular fluid filled catheter 51041 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -19.05 beats/min 23.28 61.59 vascular fluid filled catheter 51043 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 3 15.0 beats/min 17.09 29.6 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51070 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 115.76 mmHg 2.14 6.41 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51079 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 0.91 mmHg 0.96 2.14 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51082 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 -1.55 mmHg 1.88 3.77 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51081 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 10 5.72 beats/min 7.43 23.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51093 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 1.56 mmHg 1.66 4.7 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51100 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 15.43 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51105 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 384.75 beats/min 35.54 71.08 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51123 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 396.7 beats/min 7.86 19.25 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51121 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 -1.0 mmHg 2.75 7.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51135 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 137.63 mmHg 3.75 11.25 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51139 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 -16.62 beats/min 6.53 26.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51154 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -15.83 beats/min 10.21 27.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51160 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -8.42 beats/min 16.8 65.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51163 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 23.55 mmHg 4.9 10.95 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51167 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 14.94 mmHg 4.87 11.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51194 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -71.91 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51201 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -63.27 beats/min 9.59 33.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51205 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -24.8 beats/min 9.84 19.68 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51209 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -25.02 beats/min 12.07 26.99 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51213 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -22.91 beats/min 7.09 10.03 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51214 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -69.53 beats/min 11.28 27.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51225 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -61.89 beats/min 17.82 47.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51229 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 -11.35 beats/min 12.39 24.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51241 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 431.85 beats/min 7.73 20.45 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51244 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 375.94 beats/min 11.06 31.28 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51251 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 399.95 beats/min 7.51 23.75 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51253 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 393.77 beats/min 10.28 43.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51280 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 388.27 beats/min 5.75 22.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51284 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 364.35 beats/min 14.69 41.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51285 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 409.37 beats/min 12.52 35.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51292 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 133.34 mmHg 4.01 10.6 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51325 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 17 19.93 mmHg 2.55 10.53 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51336 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 46.11 beats/min 18.25 48.29 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51333 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 19.9 mmHg 4.12 10.08 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51339 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 19.93 mmHg 2.87 9.07 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51340 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 18.14 mmHg 3.11 10.77 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51342 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -65.06 beats/min 16.97 63.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51353 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -35.62 beats/min 11.0 33.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51357 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -55.31 beats/min 15.31 43.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51361 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 393.13 beats/min 12.55 28.06 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51380 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -49.04 beats/min 15.9 47.7 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51376 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 0.75 beats/min 17.84 35.68 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51377 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 377.69 beats/min 16.31 48.93 vascular fluid filled catheter 51388 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -20.91 beats/min 18.11 54.33 vascular fluid filled catheter 51413 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 18.91 mmHg 2.36 9.14 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51480 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 -5.47 mmHg 1.9 2.68 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51497 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -28.81 beats/min 15.57 46.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51514 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 3.06 beats/min 11.72 31.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51532 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 384.07 beats/min 7.11 20.11 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51575 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 328.06 beats/min 5.66 16.02 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51582 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 5.23 mmHg 1.96 5.87 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51589 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 17 3.92 mmHg 3.22 13.28 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51591 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 -2.75 mmHg 3.49 12.1 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51597 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 -4.86 mmHg 5.79 16.37 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51599 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 7.03 mmHg 3.14 9.43 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51602 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -19.53 beats/min 25.96 63.58 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51609 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -92.93 beats/min 17.96 43.99 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51607 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 373.44 beats/min 16.24 42.96 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51618 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 401.03 beats/min 10.58 27.99 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51619 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 141.2 mmHg 2.44 7.31 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51626 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 122.1 mmHg 1.91 5.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51627 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 157.55 mmHg 5.0 21.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51628 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 129.04 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51630 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -7.77 beats/min 18.13 44.41 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51674 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 451.67 beats/min 18.13 44.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50327 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 377.14 beats/min 16.4 43.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50329 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -50.41 beats/min 16.19 32.37 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50336 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -48.51 beats/min 15.93 42.16 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50339 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -33.0 beats/min 25.62 72.46 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50348 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 121.63 mmHg 2.27 6.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50350 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 3.14 mmHg 3.67 8.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50373 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -3.31 mmHg 2.75 6.73 vascular fluid filled catheter 50382 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 4.01 mmHg 4.78 9.57 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50383 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 15.74 mmHg 4.16 11.0 vascular fluid filled catheter 50405 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 11.66 mmHg 3.45 8.44 vascular fluid filled catheter 50408 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -60.38 beats/min 7.16 21.47 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50417 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 12.97 beats/min 16.28 39.87 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50426 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 440.68 beats/min 19.68 44.01 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50448 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 2.53 mmHg 2.7 7.13 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50452 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 366.2 beats/min 15.08 33.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50470 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 19 4.09 mmHg 1.31 5.69 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50498 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 11.19 beats/min 19.05 53.87 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50503 481
FHH/EurMcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 399.24 beats/min 58.09 201.23 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14718 381
SS-Chr 18BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 404.28 beats/min 8.59 29.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14722 381
FHH-Chr 1BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 350.86 beats/min 18.24 51.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14725 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 421.33 beats/min 13.57 38.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14730 381
SS-Chr 4BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 405.16 beats/min 11.58 30.65 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14734 381
SS-Chr 19BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 430.66 beats/min 7.6 13.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14731 381
SS.BN-(D13Rat111-D13Got22)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 159.0 mmHg 5.6 19.4 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5398 15
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 142.0 mmHg 1.3 4.5 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5404 15
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 181.0 mmHg 2.9 10.05 vascular fluid filled catheter left femoral artery 259200 5406 15
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 heart rate during walking-heart rate during rest 58.9 beats/min 7.95 28.66 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13396 381
SS-Chr 7BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 heart rate during walking-heart rate during rest 88.74 beats/min 9.36 31.05 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13406 381
LE/BluGill mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 112.62 mmHg 3.5 9.26 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13454 381
SS-Chr 14BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 125.85 mmHg 3.53 10.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13466 381
GH/OmrMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 157.88 mmHg 5.84 11.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13480 381
SHR/NCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 148.12 mmHg 9.3 30.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13482 381
SS-Chr 7BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 113.21 mmHg 4.96 14.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13481 381
FHH/EurMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 108.22 mmHg 2.34 6.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13487 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 119.91 mmHg 2.78 8.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13493 381
SS-Chr 4BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 130.23 mmHg 4.95 12.12 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13514 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 112.8 mmHg 7.1 12.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13520 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 118.6 mmHg 5.06 16.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13524 381
Hsd:SD absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 43.97 beats/min 15.48 30.96 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 14282 381
LEW/Crl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 21.26 mmHg 2.83 6.34 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14286 381
FHH-Chr 12BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 17 122.37 mmHg 3.52 14.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14302 381
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 121.69 mmHg 3.54 10.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14308 381
SS-Chr 17BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 123.12 mmHg 4.97 14.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14316 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 159.77 mmHg 3.14 6.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14319 381
SHR/NCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 157.62 mmHg 8.16 21.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14322 381
SS-Chr 5BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 124.62 mmHg 13.43 26.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14323 381
GH/OmrMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 163.6 mmHg 6.47 12.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14325 381
SS-Chr 7BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 106.22 mmHg 6.38 19.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14326 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 132.71 mmHg 5.85 14.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14340 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 114.28 mmHg 6.39 14.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14343 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 126.14 mmHg 3.59 10.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14344 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 61 123.16 mmHg 2.06 16.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14356 381
SS-Chr 19BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 124.2 mmHg 7.39 14.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14365 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 129.34 mmHg 5.74 18.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14364 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 146.22 mmHg 6.39 11.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14377 381
BN/NHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 121.37 mmHg 4.32 13.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14375 381
LEW/Crl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 101.12 beats/min 18.7 41.8 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17292 381
F344/DuCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 89.88 beats/min 20.7 50.72 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17293 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 120.13 mmHg 2.06 3.56 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13772 381
SS-Chr 6BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 487.66 beats/min 10.15 30.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13794 381
SS-Chr 20BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 507.3 beats/min 7.93 22.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13795 381
SS-Chr YBN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 470.17 beats/min 11.18 35.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13798 381
SS-Chr 2BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 519.62 beats/min 6.89 22.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13811 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 536.57 beats/min 8.09 14.01 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13828 381
Hsd:SD mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 115.72 mmHg 14.37 20.32 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13876 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 116.57 mmHg 6.67 16.34 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13886 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 134.71 mmHg 4.19 13.9 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13887 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 128.39 mmHg 2.11 5.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13892 381
BN/NHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 114.1 mmHg 5.91 10.24 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13894 381
FHH/EurMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 117.07 mmHg 5.96 15.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13893 381
SHR/NCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 167.7 mmHg 10.92 26.75 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13897 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 119.83 mmHg 2.16 3.05 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13903 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 96.36 mmHg 2.26 3.91 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13902 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 538.06 beats/min 13.66 30.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14064 381
LE/BluGill absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 46.94 beats/min 9.36 26.47 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14115 381
FHH/EurMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 124.62 mmHg 3.01 6.73 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14121 381
SHR/N mean arterial blood pressure control condition Innes BA, et al., Hypertension 1998 Mar;31(3):741-6 arterial blood pressure trait male 140.0 days 34 continuous mean 195.0 mmHg 1.71 10.0 vascular fluid filled catheter carotid artery 30 minutes 11665 113
SHRSP/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 126.0 days-147.0 days 13 225.2 mmHg 5.27 19.0 vascular fluid filled catheter abdominal aorta 1814400 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 21 days 12729 302
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc systolic blood pressure control condition Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 91.0 days-126.0 days 8 167.6 mmHg 2.84 8.03 vascular fluid filled catheter abdominal aorta 3024000 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 35 days 12730 302
SHRSP.WKY-(D2Mit21-D2Rat157)/Gcrc systolic blood pressure control condition Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 91.0 days-126.0 days 7 175.2 mmHg 2.7 7.14 vascular fluid filled catheter abdominal aorta 3024000 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 35 days 12732 302
WKY/N systolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait male 84.0 days 15 129.0 mmHg 8.0 30.98 vascular fluid filled catheter right carotid 13059 327
WKY/N diastolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait male 84.0 days 15 91.0 mmHg 8.0 30.98 vascular fluid filled catheter right carotid 13060 327
SS.LEW-(D5Rat130-D5Rat108)/JrMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 21 and 25 days) Roman RJ, et al., Am J Physiol Renal Physiol. 2006 Jun;290(6):F1463-71. Epub 2006 Jan 5. arterial blood pressure trait male 82.0 days-86.0 days 34 serial mean 180.0 mmHg vascular fluid filled catheter femoral artery 345600 connected to solid-state transducer (Argon Medical Technologies, Athens, TX) 5 hr recording session - 1 min. averages, averaged over 4 days 12616 272
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 134.67 mmHg 6.99 15.62 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19705 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 140.59 mmHg 8.48 18.97 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19707 381
SS-Chr 10BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 114.14 mmHg 1.77 5.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19841 381
FHH-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 116.61 mmHg 4.2 16.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19840 381
SS-Chr 6BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 113.41 mmHg 3.13 10.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19844 381
SS-Chr 6BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 121.86 mmHg 3.62 11.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19849 381
SS-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 110.34 mmHg 2.82 7.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19854 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 129.48 mmHg 7.3 17.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19860 381
SS-Chr 20BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 13 121.09 mmHg 3.34 12.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19866 381
SS-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 106.4 mmHg 2.36 6.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19862 381
FHH-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 111.94 mmHg 4.39 8.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19876 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 8.09 mmHg 6.65 18.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20712 381
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 5.9 mmHg 1.77 6.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20713 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 8.19 mmHg 2.06 4.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20719 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 7.99 mmHg 4.17 9.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20733 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 38 11.35 mmHg 1.07 6.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20729 381
SS-Chr 2BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 8.53 mmHg 2.1 6.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20740 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 15.46 mmHg 2.5 9.67 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20743 381
SS-Chr 14BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 421.61 beats/min 8.76 23.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20897 381
FHH-Chr 6BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 452.58 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20901 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 428.42 beats/min 3.12 7.65 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20910 381
SS-Chr 5BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 394.19 beats/min 29.59 59.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20914 381
SS-Chr 5BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 426.62 beats/min 36.15 51.12 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20919 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 418.51 beats/min 7.41 28.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20918 381
SS-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 446.19 beats/min 10.97 42.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20922 381
FHH-Chr 19BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 407.08 beats/min 11.09 35.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20923 381
SS-Chr 3BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 403.59 beats/min 17.14 41.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20927 381
FHH-Chr 19BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 415.47 beats/min 11.16 29.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20929 381
FHH-Chr 8BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 405.51 beats/min 33.44 74.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20932 381
FHH-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 375.98 beats/min 20.41 45.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20934 381
SS-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 400.14 beats/min 5.33 17.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20939 381
FHH-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 744.72 beats/min 191.06 467.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20954 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 401.46 beats/min 6.78 24.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20963 381
SS-Chr 2BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 432.93 beats/min 14.79 51.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20969 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 463.71 beats/min 6.73 15.05 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20973 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 63.6 beats/min 7.58 13.12 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20993 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 66.78 beats/min 18.81 46.07 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20997 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 124.73 mmHg 5.83 18.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19905 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 558.19 beats/min 18.64 41.69 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19936 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 500.7 beats/min 32.3 55.95 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19938 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 520.29 beats/min 3.33 6.65 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19951 381
SS-Chr 9BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 519.42 beats/min 5.07 13.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19959 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 504.53 beats/min 12.78 33.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19962 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 99.22 mmHg 3.82 10.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20034 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 17 115.22 mmHg 1.77 7.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20036 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 109.06 mmHg 2.91 7.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20037 381
SS-Chr 13BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 98.46 mmHg 2.78 8.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20043 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 16 111.98 mmHg 1.74 6.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20042 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 133.68 mmHg 2.07 5.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20054 381
SS-Chr 7BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 113.63 mmHg 4.28 14.21 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20060 381
SHR/NCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 131.38 mmHg 6.09 21.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20061 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 123.16 mmHg 2.21 7.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20063 381
SS-Chr 2BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 120.37 mmHg 3.29 11.4 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20062 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 110.85 mmHg 3.17 10.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20066 381
WKY/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 31.11 mmHg 5.82 14.27 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20102 381
Crl:CD(SD) mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 109.3 mmHg 3.13 8.28 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20134 381
LE/BluGill mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 106.85 mmHg 1.94 5.5 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20135 381
F344/DuCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 114.22 mmHg 4.72 14.91 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20138 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 111.35 mmHg 6.38 16.88 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19518 381
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 146.97 mmHg 8.91 21.83 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19524 381
Hsd:SD heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 405.93 beats/min 20.9 29.55 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19538 381
Crl:CD(SD) heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 424.94 beats/min 13.33 39.99 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19542 381
LEW/Crl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 113.83 mmHg 2.34 5.22 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17599 381
Hsd:SD mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 108.91 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17598 381
FHH/EurMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 407.42 beats/min vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17663 381
FHH/EurMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 419.87 beats/min 10.64 30.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17726 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 17 416.69 beats/min 12.51 51.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17728 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 424.91 beats/min 22.69 60.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17729 381
SS-Chr 13BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 431.31 beats/min 14.74 46.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17735 381
SS-Chr 6BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 14 401.94 beats/min 6.72 25.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17737 381
SS-Chr YBN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 16 399.56 beats/min 4.57 18.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17741 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 448.96 beats/min 12.9 36.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17748 381
SS-Chr 7BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 415.41 beats/min 12.98 43.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17752 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 131.74 mmHg 3.3 8.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17769 381
SS-Chr 20BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 120.3 mmHg 10.49 27.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17776 381
WKY/NCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 341.65 beats/min 14.23 45.01 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18078 381
WKY/NCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 385.12 beats/min 18.61 49.23 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18086 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 430.16 beats/min 6.98 23.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18101 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 420.82 beats/min 24.13 72.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18102 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 409.01 beats/min 5.21 12.75 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18104 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 431.68 beats/min 10.13 30.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18107 381
SS.BN-(D13Rat7-D13Rat127)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 151.0 mmHg 2.5 8.66 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65163 15
SS-Chr 20BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 115.78 beats/min 16.03 42.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18365 381
WKY/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 379.95 beats/min 14.64 35.87 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18392 381
LE/BluGill heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 424.13 beats/min 33.21 87.86 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18394 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 413.33 beats/min 15.97 45.17 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18754 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 463.94 beats/min 7.82 20.68 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18757 381
GH/OmrMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 416.79 beats/min 8.48 22.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18761 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 424.61 beats/min 10.82 28.62 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 18760 381
WKY/NCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 103.44 mmHg 3.12 10.81 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18773 381
F344/DuCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 525.85 beats/min 11.27 27.61 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18795 381
WKY/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 525.29 beats/min 2.07 3.58 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18797 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 107.32 mmHg 6.51 18.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18927 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 145.76 mmHg 4.43 6.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18940 381
SS-Chr 13BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 110.29 mmHg 4.18 12.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18936 381
SS-Chr 6BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 130.39 mmHg 2.66 7.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18938 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 120.65 mmHg 4.0 11.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18949 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 172.5 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18951 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 111.26 mmHg 2.83 10.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18958 381
Hsd:SD heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 570.06 beats/min 38.43 94.13 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 18982 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 152.36 mmHg vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19003 381
SS-Chr 10BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 363.66 beats/min 10.65 31.94 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17476 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 396.45 beats/min 10.38 31.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17477 381
SS-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 13 418.29 beats/min 10.03 36.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17480 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 434.17 beats/min 16.01 45.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17482 381
SS-Chr 14BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 396.78 beats/min 5.64 16.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17484 381
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 425.96 beats/min 24.66 73.99 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17493 381
SS-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 438.83 beats/min 28.19 84.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17499 381
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 403.88 beats/min 17.75 68.76 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17504 381
FHH-Chr 19BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 411.84 beats/min 36.75 97.23 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17511 381
FHH/EurMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 19 402.94 beats/min 12.75 55.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17524 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 393.79 beats/min 12.81 40.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17537 381
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 449.72 beats/min 33.88 58.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17543 381
FHH-Chr 7BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 428.88 beats/min 19.96 34.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17550 381
Hsd:SD heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 415.13 beats/min 13.11 52.42 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 19296 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 114.46 mmHg 5.82 14.27 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19513 381
SS.BN-(D13Rat111-D13Rat127)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 152.0 mmHg 4.4 15.24 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65167 15
SS.BN-(D13Hmgc64-RN34_13048990782)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 157.0 mmHg 5.4 18.71 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65171 15
SS.BN-(D13Rat91-D13Got45)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 169.0 mmHg 4.4 15.24 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65176 15
SS.BN-(D13Rat127-D13Rat61)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 180.0 mmHg 4.3 14.9 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65180 15
SS.BN-(D13Rat91-D13Rat179)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 173.0 mmHg 4.4 15.24 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65179 15
SS.BN-(D13Rat178-D13Got45)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 169.0 mmHg 4.2 14.55 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65184 15
SS.BN-(D13Rat61-D13GRat197)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 183.0 mmHg 2.9 10.05 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65190 15
SS.BN-(D13Rat183-D13Rat192)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 170.0 mmHg 5.8 20.09 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65196 15
SS.BN-(D13Rat151-D13Rat197)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 150.0 mmHg 2.7 9.35 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65199 15
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 415.16 beats/min 9.54 28.61 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18194 381
SS/JrHsdMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 487.67 beats/min 8.92 23.59 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18203 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 111.94 mmHg 5.03 13.31 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20400 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 117.48 mmHg 3.71 11.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20394 381
SHR/NCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 126.91 mmHg 7.17 18.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20397 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 92.85 mmHg 6.46 14.43 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20402 381
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 87.53 beats/min 4.09 9.15 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20421 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 72.51 beats/min 9.51 26.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20424 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 96.31 beats/min 29.67 78.51 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20428 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 455.4 beats/min 9.23 27.69 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20435 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 409.67 beats/min 10.1 33.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20434 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 460.16 beats/min 15.92 42.13 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20436 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 434.13 beats/min 9.78 25.88 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20442 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 382.98 beats/min 14.44 35.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20444 381
SHR/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 558.94 beats/min 12.78 28.59 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20529 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 570.99 beats/min 9.14 20.45 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20527 381
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 136.19 beats/min 6.53 13.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19164 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 88.14 beats/min 15.56 34.79 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19168 381
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 92.24 beats/min 22.5 55.1 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19169 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 159.33 beats/min 8.29 16.59 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19175 381
Hsd:SD heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 482.32 beats/min 17.94 35.89 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 16119 381
Crl:CD(SD) heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 389.59 beats/min 19.9 52.64 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16124 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 21.82 mmHg 3.62 7.24 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16251 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 408.25 beats/min 17.01 45.0 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16357 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 430.07 beats/min 13.12 32.14 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16356 381
BN/NHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 427.2 beats/min 11.52 25.76 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16359 381
SHR/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 383.91 beats/min 11.96 29.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16361 381
Hsd:SD heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 314.01 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16428 381
WKY/NCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 348.38 beats/min 12.01 41.61 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16427 381
LEW/Crl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 18 389.64 beats/min 5.09 21.58 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16429 381
Crl:CD(SD) heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 426.74 beats/min 7.88 20.86 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16432 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 5.44 mmHg 2.1 6.63 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16775 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 6.9 mmHg 3.81 8.53 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16776 381
Hsd:SD mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 117.7 mmHg 2.07 6.2 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 17459 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 110.14 mmHg 3.1 5.37 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16029 381
SR/NEisSlc heart rate controlled sodium content diet (8 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 6 342.0 beats/min 11.0 26.94 vascular fluid filled catheter 0.0 102371 2687
SR/NEisSlc heart rate controlled sodium content diet (0.3 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 7 346.0 beats/min 13.0 34.39 vascular fluid filled catheter 0.0 102370 2687
SS/NEisSlc percent change in mean arterial blood pressure controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 7 -10.6 % 3.3 8.73 vascular fluid filled catheter 0.0 102376 2687
SS/NEisSlc percent change in heart rate controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 8 -10.7 % 2.8 7.92 vascular fluid filled catheter 0.0 102381 2687
SR/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then sham surgical control condition then peanut oil (0.2 ml) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female  days 122.0 mmHg 4.0 vascular fluid filled catheter 0.0 102207 2681
SS/NEisSlc percent change in mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) and hydralazine (4 mg/ml) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 7 -22.1 % 2.5 6.61 vascular fluid filled catheter 0.0 102386 2687
LH/Mav systolic blood pressure controlled perindopril content drinking water (0.4 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 6 2hr mean (10a-12p) continuous mean 167.0 mmHg 2.0 4.9 vascular fluid filled catheter 0.0 103438 2825
LH/Mav diastolic blood pressure control condition (between 147 and 154 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 6 2hr mean (10a-12p) continuous mean 116.0 mmHg 4.0 9.8 vascular fluid filled catheter 0.0 103440 2825
LH/Mav systolic blood pressure controlled perindopril content drinking water (3 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 6 2hr mean (10a-12p) continuous mean 186.0 mmHg 8.0 19.6 vascular fluid filled catheter 0.0 103439 2825
LH/Mav diastolic blood pressure controlled perindopril content drinking water (0.4 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 6 2hr mean (10a-12p) continuous mean 121.0 mmHg 4.0 9.8 vascular fluid filled catheter 0.0 103443 2825
Crl:WI(WU) mean arterial blood pressure sham surgical control condition Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 14 103.0 mmHg 5.0 18.71 vascular fluid filled catheter 0.0 sham surgery 35 days 100021 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then icatibant (0.4 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 11 104.0 mmHg 3.0 9.95 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100028 2398
SD-Nfe2l2em1Mcwi-/- mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 35 and 49 days) Priestley JR, et al., Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H478-87. doi: 10.1152/ajpheart.00586.2015. Epub 2015 Dec 4. arterial blood pressure trait male 56.0 days-70.0 days 4 95.0 mmHg 2.6 5.2 vascular fluid filled catheter 0.0 100738 2520
LH/Mav mean arterial blood pressure right adrenalectomy (between 9 and 10 days) and right nephrectomy (between 9 and 10 days) then left kidney denervation and left adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 112.0 days 8 146.0 mmHg 5.0 14.14 vascular fluid filled catheter 0.0 104573 2970
LH/Mav mean arterial blood pressure right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 112.0 days 9 148.0 mmHg 3.0 9.0 vascular fluid filled catheter 0.0 104595 2970
LL/Mav mean arterial blood pressure right nephrectomy (between 9 and 10 days) then left kidney denervation then polyfructosan (1.25 %) (for 1.5 hours) and 0.9% sodium chloride solution (330 ul/kg/min) (for 1.5 hours) and bovine serum albumin (1 %) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 112.0 days 9 115.0 mmHg 4.0 12.0 vascular fluid filled catheter 0.0 104596 2970
LH/Mav mean arterial blood pressure right nephrectomy (between 9 and 10 days) then left kidney denervation then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) then abdominal aorta constriction and celiac artery and superior mesenteric artery constriction Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 112.0 days 8 146.0 mmHg 5.0 14.14 vascular fluid filled catheter 0.0 104597 2970
MHS mean arterial blood pressure control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 168.0 days 6 137.3 mmHg 2.41 5.9 vascular fluid filled catheter trunk of common carotid artery 0.0 104104 2907
MNS mean arterial blood pressure control condition Capasso G, et al., Am J Physiol Renal Physiol. 2005 Jun;288(6):F1173-82. doi: 10.1152/ajprenal.00228.2004. Epub 2005 Feb 1. arterial blood pressure trait not specified 23.0 days-25.0 days 11 99.4 mmHg 2.0 6.63 vascular fluid filled catheter 0.0 104160 2926
SS-Sod3m1Mcwi right ventricular end-systolic blood pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart right ventricular blood pressure trait male 56.0 days 15 57.5 mmHg 3.1 12.01 vascular fluid filled catheter 0.0 106639 3032
SS-Sod3m1Mcwi diastolic blood pressure vehicle control condition Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 8 84.2 mmHg 4.96 14.03 vascular fluid filled catheter 0.0 106807 3032
SS/JrHsdMcwi diastolic blood pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 8 85.9 mmHg 2.35 6.65 vascular fluid filled catheter 0.0 106808 3032
SS/JrHsdMcwi mean aortic pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 8 93.2 mmHg 2.33 6.59 vascular fluid filled catheter 0.0 Mean aortic pressure 106812 3032
SS-Chr 13BN/McwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 5 MAP=.33(SP-DP) + DP 112.0 mmHg 3.0 6.71 vascular fluid filled catheter femoral artery 600.0 106760 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) then 2% dimethyl sulfoxide in artificial cerebrospinal fluid (300 nl/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 150.0 mmHg 8.0 16.0 vascular fluid filled catheter femoral artery 600.0 106762 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 5 MAP=.33(SP-DP) + DP 135.0 mmHg 4.0 8.94 vascular fluid filled catheter femoral artery 600.0 106766 2685
F344/NHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 128.0 mmHg 3.0 9.49 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107332 3077
PVG/OlaHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 126.0 mmHg 3.0 9.49 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107334 3077
MWF/Hsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 138.0 mmHg 3.0 9.49 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107342 3077
BDIX/CrCrl mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 117.0 mmHg 2.0 6.32 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107343 3077
WKY/NCrl absolute change in mean arterial blood pressure artificial cerebrospinal fluid (200 nl) then angiotensin II (90 ng) then candesartan (0.5 ug) (for 0.2 hours) then angiotensin II (90 ng) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait not specified  days 4 1.0 mmHg 1.0 2.0 vascular fluid filled catheter 0.0 110106 2685
SS-Chr 14BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 127.99 mmHg 3.61 9.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15068 381
SS-Chr 6BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 14 119.35 mmHg 1.67 6.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15069 381
SS-Chr 9BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 121.13 mmHg 3.18 10.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15074 381
SS-Chr 10BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 119.36 mmHg 5.26 15.77 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15077 381
SS-Chr 6BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 125.03 mmHg 2.0 6.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15075 381
FHH-Chr 17BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 130.51 mmHg 8.41 23.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15086 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 174.8 mmHg 9.45 21.13 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15087 381
SS-Chr 5BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 123.94 mmHg 2.73 3.85 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15090 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 131.03 mmHg 4.36 13.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15094 381
SS-Chr YBN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 18 124.0 mmHg 2.7 11.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15115 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 124.5 mmHg 2.7 8.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15123 381
SS-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 114.49 mmHg 11.8 26.38 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15128 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 126.48 mmHg 8.9 15.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15132 381
SS-Chr 2BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 124.3 mmHg 7.17 22.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15133 381
SS-Chr XBN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 140.41 mmHg 7.53 19.92 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15138 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 113.99 mmHg 3.85 10.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15141 381
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 1 -1.92 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15149 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 20.79 mmHg 3.5 8.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15154 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 3 22.11 mmHg 6.48 11.23 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15159 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 427.49 beats/min 15.86 38.84 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15191 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 474.88 beats/min 17.79 39.79 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15192 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 136.55 mmHg 6.41 18.12 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15200 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 117.1 mmHg 0.61 1.37 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15201 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 147.51 mmHg 7.03 18.61 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15202 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 169.25 mmHg 4.4 11.63 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 15206 381
Hsd:SD absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 10.56 mmHg 2.75 8.24 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15482 381
Hsd:SD heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 377.42 beats/min 7.29 20.61 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15519 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 13.21 mmHg 6.38 16.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15541 381
SS/JrHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 10.6 mmHg 4.12 10.9 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15544 381
Hsd:SD heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 427.86 beats/min 13.06 41.31 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 15755 381
Hsd:SD heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 389.53 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15782 381
LEW/Crl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 14 484.39 beats/min 8.01 29.97 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15783 381
WKY/NCrl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 440.1 beats/min 13.78 30.81 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15781 381
LE/BluGill heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 482.97 beats/min 7.02 19.86 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15787 381
LEW/Crl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 472.31 beats/min 12.69 45.77 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15788 381
Hsd:SD mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 123.14 mmHg 10.33 14.6 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15793 381
Crl:CD(SD) mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 110.69 mmHg 6.18 18.54 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15797 381
LE/BluGill mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 109.91 mmHg 3.14 9.41 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 15802 381
SS-Chr 10BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 417.15 beats/min 14.1 42.31 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15903 381
SS-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 421.78 beats/min 10.42 29.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15916 381
SS-Chr 6BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 417.55 beats/min 10.2 32.26 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15911 381
SS-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 453.22 beats/min 9.74 27.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15924 381
FHH-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 417.53 beats/min 15.72 44.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15926 381
FHH-Chr 8BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 378.8 beats/min 6.76 17.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15937 381
SS-Chr 18BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 389.67 beats/min 10.03 24.58 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15335 381
SHR/NCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 479.96 beats/min 14.71 36.03 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 15339 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 132.16 mmHg 5.14 13.61 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14416 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 122.15 mmHg 2.63 6.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14652 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 131.18 mmHg 17.56 30.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14655 381
GH/OmrMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 155.76 mmHg 12.21 29.92 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14659 381
FHH/EurMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 113.88 mmHg 7.4 22.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14662 381
SHR/NCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 150.49 mmHg 9.72 19.45 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14671 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 14 369.92 beats/min 5.45 20.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14674 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 384.04 beats/min 13.45 40.35 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14678 381
FHH-Chr 19BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 372.21 beats/min 13.69 33.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14699 381
SS-Chr 15BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 2 344.65 beats/min 33.31 47.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14704 381
FHH-Chr 20BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 380.77 beats/min 9.2 22.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14714 381
SS-Chr 3BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 458.32 beats/min 23.26 40.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15939 381
SS-Chr 20BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 420.34 beats/min 8.83 29.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15945 381
FHH-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 383.94 beats/min 22.36 50.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15943 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 12 437.33 beats/min 12.59 43.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15952 381
SS-Chr XBN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 432.35 beats/min 11.2 19.4 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15954 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 447.42 beats/min 9.78 27.65 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15960 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 452.55 beats/min 9.34 29.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15958 381
SS-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 464.94 beats/min 13.07 26.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15968 381
SS-Chr 2BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 426.12 beats/min 15.9 44.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15966 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 395.53 beats/min 6.9 21.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 15967 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 4 126.47 mmHg 4.99 9.97 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16023 381
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -98.78 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51693 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 -61.3 beats/min 5.87 18.56 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51695 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 21.02 beats/min 15.06 42.58 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51698 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -3.72 beats/min 14.86 33.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51703 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -64.96 beats/min 12.05 45.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51708 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -83.44 beats/min 10.79 41.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51713 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -4.99 beats/min 8.54 33.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51719 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -0.83 beats/min 8.19 21.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51724 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 10.79 beats/min 17.8 35.6 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51723 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -26.04 beats/min 15.48 46.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51726 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 8.33 beats/min 25.63 62.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51728 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 111.8 mmHg 2.06 6.17 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51732 481
F344/DuCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 109.83 mmHg 2.62 7.87 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51734 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 9.32 mmHg 2.42 6.86 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51740 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 27.25 mmHg 4.3 9.62 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51770 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 380.88 beats/min 3.51 7.84 vascular fluid filled catheter 51781 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 336.79 beats/min 11.9 35.71 vascular fluid filled catheter 51780 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 2.35 beats/min 11.45 28.06 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51790 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 5.85 beats/min 23.31 61.68 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51794 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 14.36 mmHg 3.33 7.45 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51816 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 119.18 mmHg 4.9 12.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51819 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 127.98 mmHg 2.2 6.22 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51825 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 146.56 mmHg 2.45 6.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51827 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 121.77 mmHg 0.93 2.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51829 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -25.56 beats/min 21.49 48.06 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51847 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 37.93 beats/min 11.28 27.64 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51851 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 -18.95 beats/min 6.48 20.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51852 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -42.21 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51850 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 34.22 beats/min 12.04 36.13 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51853 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 9.85 beats/min 13.56 38.36 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51857 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 21.95 mmHg 2.41 6.38 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51861 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 12 16.35 mmHg 2.77 9.58 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51869 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 19.38 mmHg 3.3 6.6 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51873 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 13.05 mmHg 2.64 7.47 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51874 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 20 11.22 beats/min 7.91 35.37 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51875 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 115.67 mmHg 1.6 4.24 vascular fluid filled catheter 51880 481
WKY/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 119.39 mmHg 2.87 7.59 vascular fluid filled catheter 51906 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 18.8 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51913 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -3.32 beats/min 20.7 62.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51918 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -33.57 beats/min 24.8 65.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51926 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -101.53 beats/min 14.79 44.38 vascular fluid filled catheter 51937 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 21.26 mmHg 2.2 8.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51963 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -88.23 beats/min 14.4 38.11 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51989 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 117.87 mmHg 3.37 7.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52000 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 160.79 mmHg 5.64 16.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51999 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 122.5 mmHg 2.84 10.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52006 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 137.69 mmHg 5.58 13.68 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52005 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 91.89 mmHg 3.36 7.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52008 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 156.06 mmHg 6.95 17.02 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52002 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 14 123.13 mmHg 1.84 6.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52004 481
WKY/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -4.08 mmHg 3.15 9.46 vascular fluid filled catheter 52023 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 394.18 beats/min 3.77 9.98 vascular fluid filled catheter 52032 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 393.92 beats/min 17.82 47.16 vascular fluid filled catheter 52033 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 370.41 beats/min 5.95 15.75 vascular fluid filled catheter 52034 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -32.36 beats/min 13.84 30.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52050 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 13.2 beats/min 21.2 56.1 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52055 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -26.95 beats/min 8.55 29.62 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 52054 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -16.77 beats/min 3.09 6.9 vascular fluid filled catheter 52065 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -23.46 beats/min 11.46 22.92 vascular fluid filled catheter 52066 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -144.07 beats/min 13.19 51.07 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52073 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -2.26 beats/min 17.07 45.17 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 52071 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -35.03 beats/min 21.41 56.65 vascular fluid filled catheter 52081 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 137.62 mmHg 4.07 15.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52084 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -10.22 beats/min 19.9 59.69 vascular fluid filled catheter 52080 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 125.83 mmHg 3.49 8.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52088 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 135.1 mmHg 2.34 8.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52089 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 159.87 mmHg 7.95 19.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 52093 481
SS-Chr 6BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 10 176.2 mmHg 5.38 17.0 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52837 482
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 161.62 mmHg 5.67 17.01 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52845 482
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 155.24 mmHg 2.9 8.7 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52850 482
SS-Chr 11BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 15 161.86 mmHg 5.89 22.8 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52854 482
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 18 143.27 mmHg 0.95 4.05 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52855 482
SS-Chr 4BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 180.66 mmHg 6.43 17.02 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52864 482
SS-Chr 12BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 6 143.57 mmHg 5.12 12.54 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52873 482
SS-Chr XBN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 5 176.37 mmHg 14.75 32.98 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52876 482
FHH/EurMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 15 429.33 beats/min 8.27 32.03 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52487 482
FHH-Chr 19BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 418.42 beats/min 10.21 27.01 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52488 482
FHH-Chr 19BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 6 434.17 beats/min 11.32 27.72 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52494 482
FHH-Chr 15BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 7 396.79 beats/min 11.52 30.48 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52506 482
FHH-Chr 14BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 8 405.62 beats/min 14.94 42.25 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52508 482
FHH-Chr YBN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 4 410.74 beats/min 18.25 36.49 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52509 482
FHH-Chr 11BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 4 431.62 beats/min 7.42 14.85 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52518 482
FHH-Chr 11BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 5 419.76 beats/min 9.0 20.13 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52520 482
BN/NHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 8 349.72 beats/min 7.76 21.94 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52524 482
FHH-Chr 16BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 8 414.64 beats/min 10.79 30.52 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52529 482
FHH-Chr 19BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 7 166.08 mmHg 8.23 21.77 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52535 482
FHH-Chr 2BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 5 156.33 mmHg 11.05 24.71 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52538 482
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 48 181.54 mmHg 2.9 20.07 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52552 482
FHH-Chr 7BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 9 148.65 mmHg 7.47 22.42 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52569 482
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait female 80.0 days-99.0 days 8 126.28 mmHg 8.23 23.29 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52572 482
FHH-Chr 7BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data arterial blood pressure trait male 80.0 days-99.0 days 9 185.36 mmHg 6.33 18.99 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52575 482
LE/BluGill heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 9 429.78 beats/min 17.94 53.83 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52629 482
LE/BluGill heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 382.48 beats/min 3.97 10.5 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52630 482
SS-Chr 10BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 10 375.56 beats/min 6.69 21.15 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52631 482
SS-Chr 14BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 8 389.33 beats/min 13.3 37.62 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52637 482
SS-Chr 17BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 6 433.58 beats/min 14.87 36.43 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52643 482
SS-Chr 15BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 364.71 beats/min 8.9 23.56 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52649 482
SS-Chr 3BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 408.25 beats/min 5.72 17.16 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52651 482
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 9 385.81 beats/min 7.21 21.63 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52652 482
SS-Chr 13BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 17 408.19 beats/min 2.95 12.16 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52653 482
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 10 406.58 beats/min 6.69 21.14 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52664 482
SS/JrHsdMcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 59 400.39 beats/min 4.05 31.09 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52661 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait female 80.0 days-99.0 days 11 396.87 beats/min 4.2 13.92 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52668 482
SS-Chr 19BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 5 386.99 beats/min 19.02 42.54 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52669 482
SS-Chr 12BN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 7 358.72 beats/min 9.8 25.93 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52670 482
SS-Chr XBN/Mcwi heart rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data heart pumping trait male 80.0 days-99.0 days 5 412.92 beats/min 8.39 18.77 vascular fluid filled catheter Moms were fed Teklad, pups used in studies were fed Dyets 52678 482
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 429.89 beats/min 16.83 50.48 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50521 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 434.72 beats/min 6.45 14.42 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50522 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -2.43 beats/min 15.64 46.93 vascular fluid filled catheter 50517 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -28.64 beats/min 27.38 61.23 vascular fluid filled catheter 50516 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 399.8 beats/min 23.32 46.63 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50533 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 402.53 beats/min 6.39 15.65 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50576 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -34.01 beats/min 27.27 81.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50580 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -20.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50581 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -48.54 beats/min 8.85 34.28 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50585 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -66.96 beats/min 13.29 51.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50587 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -58.69 beats/min 20.55 54.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50588 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 0.53 mmHg 1.24 2.77 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50601 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 15.65 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50602 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 3.2 mmHg 1.6 5.56 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50603 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 7.61 mmHg 2.63 6.95 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50606 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -31.8 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50615 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -9.37 beats/min 17.56 46.46 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50614 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 -3.71 beats/min 10.56 33.39 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50617 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 -3.9 mmHg 1.51 3.99 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50626 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -1.4 beats/min 7.97 22.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50622 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 -22.81 mmHg 3.9 16.57 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50627 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 139.27 mmHg 3.66 10.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50638 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 136.5 mmHg 3.86 12.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50644 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 157.81 mmHg 6.04 25.64 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50640 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 161.63 mmHg 6.61 14.78 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50643 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 16 33.3 mmHg 3.27 13.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50653 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 427.03 beats/min 9.64 21.56 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50668 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 55.32 mmHg 2.61 6.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50663 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 39.82 mmHg 2.4 6.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50665 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -18.2 beats/min 46.2 65.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50681 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 26.95 beats/min 7.31 28.3 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50683 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 2.83 beats/min 19.88 56.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50687 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 5.74 mmHg 2.11 8.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50696 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 6.32 mmHg 3.54 7.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50702 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 3.55 mmHg 3.77 10.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50707 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -38.96 beats/min 35.44 79.25 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50719 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 24.4 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50722 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 12 -50.68 beats/min 14.96 51.82 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50723 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -11.63 beats/min 18.33 44.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50725 481
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 131.66 mmHg 1.66 6.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50738 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 186.62 mmHg 6.38 19.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50740 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 29.82 mmHg 4.61 12.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50750 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 45.19 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50751 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 27.55 mmHg 4.09 11.58 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50757 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 -11.26 mmHg 2.11 5.58 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50766 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -0.91 mmHg 3.29 9.86 vascular fluid filled catheter 50770 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 2.17 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50773 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 2 2.52 mmHg 6.42 9.08 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50775 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -1.42 mmHg 2.23 5.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50778 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 37.27 mmHg 5.13 11.48 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50788 481
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 124.3 mmHg 1.8 4.42 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50793 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 140.46 mmHg 4.67 12.37 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50795 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 114.24 mmHg 2.67 5.98 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50796 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 -12.57 mmHg 1.76 6.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50801 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 -3.43 mmHg 1.25 2.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50804 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 -15.3 mmHg 6.88 16.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50809 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 -15.73 mmHg 1.65 6.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50810 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 -7.15 mmHg 2.83 6.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50812 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 14 428.56 beats/min 6.77 25.34 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50815 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 10.83 beats/min 10.18 20.36 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50822 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 3.21 beats/min 10.2 26.99 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50825 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 20 30.61 mmHg 1.78 7.98 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50826 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -0.68 mmHg 4.11 12.32 vascular fluid filled catheter 50830 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 3 21.03 mmHg 14.54 25.18 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50841 481
LEW/Crl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 96.06 mmHg 2.3 4.61 vascular fluid filled catheter 50838 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 8.97 mmHg 1.29 2.89 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50844 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 404.0 beats/min 22.43 59.35 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50855 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 6.01 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50860 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 11.78 mmHg 2.52 5.04 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50857 481
Crl:CD(SD) heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 420.92 beats/min 8.61 17.21 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50863 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 35.88 mmHg 3.36 8.9 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50875 481
SS/JrHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 386.98 beats/min 5.77 22.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50878 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 387.54 beats/min 13.35 26.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50888 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 6.57 beats/min 9.35 22.89 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50892 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 34.96 mmHg 5.65 13.85 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50899 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 8.29 beats/min 21.22 47.46 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50905 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 21.19 beats/min 4.88 10.9 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50907 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 4.08 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50912 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 383.46 beats/min 6.17 25.44 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50923 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 4 5.4 mmHg 1.79 3.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50921 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 18 -5.4 mmHg 2.47 10.48 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50927 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 -6.74 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50929 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 7.25 mmHg 1.97 5.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50933 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 -1.98 mmHg 1.94 5.83 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50935 481
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 133.88 mmHg 3.26 12.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50940 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 158.06 mmHg 6.12 18.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50941 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -27.15 beats/min 19.46 38.92 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50952 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -12.2 beats/min 20.46 50.11 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50953 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 33.88 mmHg 3.14 12.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50970 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -53.36 beats/min 15.31 40.5 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50975 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 3.44 beats/min 4.53 17.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50977 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 17.34 beats/min 5.18 12.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50985 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 4.02 mmHg 4.61 10.32 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50996 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 1 16.23 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51022 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 33.82 mmHg 2.59 10.04 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51033 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 -54.89 beats/min 10.39 23.23 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51034 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -55.8 beats/min 16.75 44.32 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51035 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 -15.33 beats/min 20.43 50.04 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51071 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 15.99 beats/min 25.85 57.8 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51073 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 5 21.44 beats/min 7.45 16.66 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51074 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 -0.81 mmHg 2.41 6.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51085 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 3 -11.72 beats/min 10.1 17.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51090 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -6.87 beats/min 2.38 6.72 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51092 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 21.46 beats/min 11.94 37.77 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51091 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 17.17 beats/min 7.37 23.3 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51096 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 9.79 mmHg 2.4 7.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51099 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 3.87 mmHg 2.0 4.48 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51102 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 0.6 mmHg 0.68 1.94 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51111 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 454.95 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51116 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 390.4 beats/min 15.58 41.22 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51120 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 13.1 mmHg 2.68 8.04 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51127 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 11.29 mmHg 3.25 12.16 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51134 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 -0.23 mmHg 3.97 9.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51138 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 122.0 mmHg 3.95 8.84 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51140 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 17 157.61 mmHg 4.84 19.98 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51141 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 142.44 mmHg 3.02 9.56 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51145 481
GH/OmrMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 155.67 mmHg 6.53 16.0 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51144 481
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 107.04 mmHg 4.18 12.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51152 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 14 -23.73 beats/min 13.2 49.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51158 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 6 7.8 beats/min 15.51 37.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51161 481
BN/NHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 -35.16 beats/min 11.36 32.12 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51166 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 27.84 mmHg 2.7 10.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51188 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 31.18 mmHg 4.47 13.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51192 481
SS-Chr 16BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -10.29 beats/min 19.56 51.74 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51200 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 17 -27.92 beats/min 8.05 33.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51199 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -13.98 beats/min 6.5 15.92 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51211 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -13.26 beats/min 12.39 24.79 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51212 481
SS-Chr 20BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 -57.31 beats/min 9.57 37.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51219 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 16 -48.18 beats/min 8.64 34.54 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51218 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 -12.98 beats/min 20.48 40.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51223 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 -21.13 beats/min 8.39 25.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51231 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 4.3 beats/min 93.3 131.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51234 481
SS-Chr 9BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 -15.78 beats/min 13.94 54.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51238 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -14.73 beats/min 16.5 40.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51242 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 10 386.76 beats/min 11.54 36.49 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51248 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 321.19 beats/min 5.4 15.26 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51249 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 18.95 beats/min 7.34 17.98 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51260 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 420.94 beats/min 4.88 18.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51287 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 408.04 beats/min 7.45 21.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51291 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 3 -0.13 beats/min 21.53 37.29 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51303 481
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 117.49 mmHg 2.54 5.67 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51324 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 24.08 mmHg 4.27 12.8 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51341 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 3.45 mmHg 3.89 11.0 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51344 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 89.93 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51370 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 19.91 beats/min 16.5 43.65 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51374 481
LEW/Crl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 398.86 beats/min 10.67 28.23 vascular fluid filled catheter 51387 481
WKY/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 430.77 beats/min 14.45 38.23 vascular fluid filled catheter 51389 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 0.85 mmHg 4.77 14.32 vascular fluid filled catheter 51396 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 5 -39.28 beats/min 14.49 32.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51408 481
WKY/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -24.26 beats/min 15.5 46.5 vascular fluid filled catheter 51411 481
LEW/Crl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 2.2 beats/min 15.19 40.18 vascular fluid filled catheter 51412 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 10.13 mmHg 4.49 10.03 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51415 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 1.72 mmHg 2.98 7.88 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51416 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 2.02 mmHg 2.22 5.88 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51418 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 39.28 mmHg 2.49 7.47 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51419 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 10 37.12 mmHg 3.33 10.54 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51425 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 6 38.71 mmHg 5.37 13.15 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51424 481
FHH/EurMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 8 38.72 mmHg 3.96 11.19 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51430 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 420.76 beats/min 4.93 13.05 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51483 481
SS-Chr 18BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 445.12 beats/min 21.94 43.88 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51485 481
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 4 21.74 mmHg 2.32 4.63 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51489 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 7 37.22 mmHg 3.1 8.19 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51492 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 5 6.54 mmHg 3.5 7.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51498 481
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 4.91 mmHg 1.26 2.83 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51499 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 3.18 beats/min 9.27 26.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51510 481
FHH/EurMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 8 428.75 beats/min 6.19 17.5 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51576 481
SHR/NCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (for 0.2 hours) then angiotensin (50 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 2.21 mmHg 3.87 11.6 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51596 481
Hsd:SD absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 7 -5.39 beats/min 12.75 33.74 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51615 481
F344/DuCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 419.97 beats/min 10.58 27.98 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51617 481
SHR/NCrl mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 1 140.45 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51632 481
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 12 139.35 mmHg 3.58 12.4 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51631 481
FHH/EurMcwi mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 127.19 mmHg 1.83 5.49 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 51636 481
SS-Chr 20BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 15 36.48 mmHg 2.7 10.45 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 51662 481
Crl:CD(SD) absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 4.73 beats/min 17.72 35.45 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51675 481
Hsd:SD heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 15 433.67 beats/min 8.21 31.78 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51678 481
SS-Chr 20BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 407.4 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50322 481
F344/DuCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 8.4 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51676 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 374.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50325 481
SS-Chr 9BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 15 401.33 beats/min 7.65 29.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50328 481
BN/NHsdMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 4 435.45 beats/min 18.67 37.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50331 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 6 -6.63 beats/min 20.93 51.28 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50335 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 8 -16.95 beats/min 18.35 51.9 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50340 481
Crl:CD(SD) mean arterial blood pressure controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 5 123.14 mmHg 6.55 14.64 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50349 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -91.71 beats/min 8.29 11.72 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50346 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 -34.8 beats/min 65.4 92.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50356 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -32.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50357 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -65.03 beats/min 16.82 44.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50361 481
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 14 9.79 mmHg 2.68 10.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50370 481
GH/OmrMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 9 4.74 mmHg 3.46 10.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50368 481
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 8 3.61 mmHg 1.8 5.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50378 481
F344/DuCrl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 2.78 mmHg 1.91 4.67 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50384 481
LEW/Crl absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 9 3.28 mmHg 2.03 6.1 vascular fluid filled catheter 50407 481
SHR/NCrl absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 1 105.2 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50423 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 -32.32 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50421 481
GH/OmrMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 7 -16.29 beats/min 8.71 23.05 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50425 481
SS-Chr 18BN/Mcwi absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data arterial blood pressure trait male 87.0 days-120.0 days 6 -1.93 mmHg 2.59 6.35 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50430 481
SS-Chr 16BN/Mcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 2 455.2 beats/min 31.4 44.41 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50447 481
Crl:CD(SD) absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 7.33 mmHg 1.67 4.42 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50453 481
GH/OmrMcwi heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 9 400.42 beats/min 13.3 39.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50473 481
SHR/NCrl heart rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 4 349.08 beats/min 20.02 40.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 50476 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then angiotensin (5 ng/kg/min) (for 0.2 hours) then angiotensin (10 ng/kg/min) (for 0.2 hours) then angiotensin (25 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 15 8.67 mmHg 1.66 6.43 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50499 481
Hsd:SD absolute change in mean arterial blood pressure controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (between 0.2 and 0.2 hours) PhysGen Renal A data arterial blood pressure trait female 87.0 days-120.0 days 7 2.74 mmHg 2.53 6.7 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50501 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 20.02 beats/min 10.69 32.07 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50502 481
SS/JrHsdMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 18 -9.03 beats/min 7.32 31.07 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50504 481
SS-Chr 18BN/Mcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait female 87.0 days-120.0 days 1 2.02 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50506 481
FHH/EurMcwi absolute change in heart rate controlled sodium content diet (4 %) (between 24 and 31 days) then norepinephrine (0.1 ng/kg/min) (for 0.2 hours) then norepinephrine (0.2 ng/kg/min) (for 0.2 hours) then norepinephrine (0.5 ng/kg/min) (for 0.2 hours) then norepinephrine (1 ng/kg/min) (for 0.2 hours) PhysGen Renal A data heart pumping trait male 87.0 days-120.0 days 9 -24.77 beats/min 14.96 44.88 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 50512 481
SS-Chr XBN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 424.24 beats/min 20.4 35.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14724 381
SS-Chr 4BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 382.97 beats/min 23.85 58.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14727 381
SS-Chr 18BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 405.29 beats/min 10.69 32.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14726 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 10 362.13 beats/min 9.77 30.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14737 381
SS-Chr XBN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 387.81 beats/min 19.81 48.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14741 381
SS-Chr 2BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 371.2 beats/min 13.44 38.01 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14743 381
FHH-Chr 1BN/Mcwi heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 410.56 beats/min 14.13 37.38 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14744 381
SS.BN-(D13Rat7-D13Rat60)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 165.0 mmHg 6.6 22.86 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5396 15
SS.BN-(D13Rat111-D13Got22)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 152.0 mmHg 4.4 15.24 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5397 15
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 137.0 mmHg 1.9 6.58 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 5403 15
SS-Chr 20BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 heart rate during walking-heart rate during rest 61.74 beats/min 7.76 26.88 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13382 381
SS-Chr 9BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 heart rate during walking-heart rate during rest 90.8 beats/min 10.65 30.11 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13386 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 heart rate during walking-heart rate during rest 101.97 beats/min 7.94 17.75 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13387 381
SS-Chr 13BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 heart rate during walking-heart rate during rest 56.11 beats/min 9.35 28.04 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13389 381
SS-Chr 2BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 heart rate during walking-heart rate during rest 101.42 beats/min 7.49 24.86 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13408 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 heart rate during walking-heart rate during rest 65.27 beats/min 13.49 42.65 vascular fluid filled catheter 0 Moms and pups used in studies were fed Teklad 13407 381
Crl:CD(SD) mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 121.24 mmHg 5.98 16.92 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13451 381
F344/DuCrl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 110.13 mmHg 2.89 8.16 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13452 381
LEW/Crl mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 106.23 mmHg 4.07 13.5 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13455 381
FHH-Chr 12BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 113.14 mmHg 3.66 14.18 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13459 381
SS-Chr 9BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 121.43 mmHg 2.32 7.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13464 381
FHH-Chr 12BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 115.03 mmHg 2.48 7.83 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13469 381
SS-Chr 7BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 118.5 mmHg 4.3 11.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13473 381
GH/OmrMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 153.47 mmHg 5.91 14.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13474 381
SS-Chr 5BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 2 98.28 mmHg 4.6 6.5 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13478 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 119.49 mmHg 2.49 6.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13484 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 105.93 mmHg 3.52 10.55 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13488 381
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 115.54 mmHg 4.06 13.46 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13502 381
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 116.97 mmHg 2.46 6.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13506 381
FHH/EurMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 119.62 mmHg 3.34 11.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13505 381
SS-Chr YBN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 16 122.07 mmHg 3.36 13.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13507 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 120.39 mmHg 5.08 14.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13512 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 51 123.21 mmHg 1.69 12.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13510 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 108.29 mmHg 3.98 11.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13513 381
SS-Chr 2BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 126.07 mmHg 5.22 15.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13523 381
SS-Chr XBN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 121.67 mmHg 8.3 20.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13528 381
BN/NHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 119.56 mmHg 2.71 8.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13527 381
BN/NHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 126.58 mmHg 4.94 13.97 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13526 381
Hsd:SD absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 41.83 beats/min 10.63 31.9 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 14283 381
WKY/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 9.35 mmHg 4.99 8.65 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14289 381
F344/DuCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 7.62 mmHg 1.38 2.76 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 14290 381
SS-Chr 6BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 13 112.2 mmHg 2.36 8.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14307 381
SS-Chr 10BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 110.5 mmHg 2.9 8.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14315 381
SS-Chr 20BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 109.28 mmHg 5.62 21.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14331 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 110.41 mmHg 8.6 22.75 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14338 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 118.55 mmHg 2.03 6.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14339 381
FHH-Chr 20BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 116.3 mmHg 4.26 11.27 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14347 381
FHH/EurMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 18 123.86 mmHg 3.79 16.1 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14351 381
SS-Chr 13BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 120.5 mmHg 4.3 12.17 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14352 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 107.22 mmHg 5.67 18.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14359 381
SS/JrHsdMcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 122.71 mmHg 2.46 7.78 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14361 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 119.96 mmHg 9.79 16.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 14370 381
Hsd:SD absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 1 152.16 beats/min vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17291 381
WKY/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 114.08 beats/min 3.93 6.8 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17295 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 116.95 mmHg 2.56 5.73 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13766 381
SHR/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 135.95 mmHg 5.66 13.87 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13768 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 123.62 mmHg 1.98 5.6 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13767 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 120.99 mmHg 1.94 4.75 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13770 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 104.41 mmHg 3.03 6.77 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13773 381
SS-Chr 9BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 505.2 beats/min 5.8 16.41 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13789 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 527.25 beats/min 6.51 25.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13791 381
SS-Chr 9BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 485.32 beats/min 10.66 33.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13793 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 37 492.45 beats/min 5.9 35.89 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13800 381
GH/OmrMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 4 524.85 beats/min 14.03 28.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13802 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 481.5 beats/min 12.68 42.05 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13812 381
BN/NHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 470.72 beats/min 12.36 47.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 13814 381
FHH/EurMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 490.57 beats/min 20.05 34.73 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13827 381
F344/DuCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 112.39 mmHg 3.16 10.96 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13879 381
F344/DuCrl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 113.26 mmHg 6.39 21.2 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13884 381
LEW/Crl mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 16 95.21 mmHg 5.41 21.65 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13882 381
LE/BluGill mean arterial blood pressure controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 109.87 mmHg 6.68 20.03 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 13885 381
SS-Chr 18BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 113.09 mmHg 6.11 16.16 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13891 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 124.97 mmHg 1.77 5.0 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13889 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 132.8 mmHg 6.49 18.34 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 13896 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 108.33 mmHg 5.29 9.16 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 13906 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 540.89 beats/min 7.28 17.82 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14068 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 531.15 beats/min 5.18 13.7 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 14072 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 107.33 beats/min 30.55 52.91 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14103 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 151.3 beats/min 23.87 53.38 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14105 381
GH/OmrMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 79.66 beats/min 18.58 41.54 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14108 381
GH/OmrMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 132.81 mmHg 16.88 29.24 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14123 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 121.45 mmHg 3.1 8.21 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14120 381
SS/JrHsdMcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 119.26 mmHg 4.6 9.21 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14126 381
SS-Chr 16BN/Mcwi mean arterial blood pressure controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 117.55 mmHg 7.05 9.96 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 14124 381
SHRSP.WKY-(D2Rat13-D2Rat157)/Gcrc systolic blood pressure controlled sodium content drinking water (1 %) (for 21 days) Graham D, et al., Hypertension. 2007 Dec; 50(6):1134-41. arterial blood pressure trait male 126.0 days-147.0 days 8 189.6 mmHg 3.43 9.7 vascular fluid filled catheter abdominal aorta 1814400 implanted at 84 days with 7 day recovery; Dataquest IV telemetry system (Data Sciences International) averaged over 21 days 12731 302
SHR/N mean arterial blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait male 84.0 days 14 157.0 mmHg 8.0 29.93 vascular fluid filled catheter right carotid 13045 327
SHR/N diastolic blood pressure control condition Ye P and West MJ, Clin Exp Pharmacol Physiol 2003 Dec;30(12):930-6. arterial blood pressure trait female 84.0 days 16 129.0 mmHg 8.0 32.0 vascular fluid filled catheter right carotid 13052 327
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 103.92 mmHg 3.76 9.21 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19708 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 127.7 mmHg 4.31 10.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19709 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 112.4 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19711 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 14 123.56 mmHg 2.52 9.43 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19842 381
FHH-Chr 12BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 119.12 mmHg 2.99 9.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19850 381
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 149.42 mmHg 2.72 7.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19858 381
FHH-Chr 19BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 138.57 mmHg 11.25 27.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19867 381
FHH-Chr 8BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 119.3 mmHg 2.54 6.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19865 381
SS-Chr 3BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 123.13 mmHg 3.42 7.64 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19871 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 111.17 mmHg 2.54 7.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19874 381
SS-Chr 13BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 114.2 mmHg 5.68 15.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19880 381
FHH-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 128.88 mmHg 5.13 11.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19881 381
SS-Chr 18BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 111.01 mmHg 3.9 13.53 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19890 381
SS-Chr YBN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 16 120.47 mmHg 3.7 14.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19888 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 127.02 mmHg 7.22 20.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19898 381
FHH-Chr 11BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 50.43 mmHg 33.41 74.71 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19897 381
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 9.49 mmHg 3.2 9.06 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20718 381
SS-Chr 9BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 9.8 mmHg 3.86 11.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20722 381
SS-Chr 6BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 14.31 mmHg 2.06 6.19 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20723 381
GH/OmrMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 9.7 mmHg 3.99 7.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20732 381
SHR/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 3.77 mmHg 4.08 12.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20739 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 25.28 mmHg 2.6 9.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20742 381
FHH-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 17 407.29 beats/min 10.17 41.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20893 381
SS-Chr 10BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 392.09 beats/min 11.91 35.73 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20894 381
SS-Chr 6BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 14 428.68 beats/min 7.37 27.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20898 381
FHH-Chr 12BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 415.2 beats/min 13.22 43.84 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20905 381
SS-Chr 6BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 422.11 beats/min 12.15 40.29 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20904 381
SS-Chr 7BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 409.94 beats/min 10.52 31.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20909 381
FHH-Chr 8BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 413.03 beats/min 15.54 43.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20921 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 442.47 beats/min 11.61 40.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20925 381
SS-Chr 11BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 397.47 beats/min 26.42 69.9 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20941 381
SS-Chr YBN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 18 406.55 beats/min 10.33 43.82 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20944 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 18 372.15 beats/min 12.1 51.33 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20942 381
FHH-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 400.95 beats/min 13.32 42.11 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20940 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 13 414.26 beats/min 7.06 25.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20946 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 431.53 beats/min 10.68 35.44 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20950 381
SS-Chr 4BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 422.29 beats/min 10.87 26.63 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20951 381
SS-Chr 19BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 480.45 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20960 381
SS-Chr 2BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 414.41 beats/min 20.67 65.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20962 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 449.22 beats/min 9.2 26.02 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20972 381
GH/OmrMcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 449.86 beats/min 12.26 32.43 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20974 381
FHH/EurMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 408.42 beats/min 19.73 48.32 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20976 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 96.5 beats/min 10.79 18.69 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20992 381
SS/JrHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 49.95 beats/min 66.91 133.82 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 20990 381
BN/NHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 11 112.33 mmHg 4.1 13.59 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19908 381
SS-Chr XBN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 126.82 mmHg 9.04 22.14 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19909 381
FHH-Chr 1BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 116.34 mmHg 5.47 14.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19912 381
FHH-Chr 7BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 125.39 mmHg vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19910 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 510.22 beats/min 28.21 63.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19955 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 538.01 beats/min 10.27 25.15 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19960 381
SS-Chr 20BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 516.21 beats/min 14.36 38.0 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19967 381
SS/JrHsdMcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 517.01 beats/min 6.36 16.81 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 19963 381
SS-Chr 9BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 9 113.64 mmHg 2.16 6.47 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20040 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 8 109.01 mmHg 2.05 5.8 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20041 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 116.22 mmHg 2.74 9.87 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20050 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 48 117.4 mmHg 1.68 11.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20051 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 113.6 mmHg 4.17 9.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20055 381
SS-Chr 7BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 118.88 mmHg 4.95 13.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20053 381
SS.BN-(D8Rat163-D8Rat81)/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 9 107.6 mmHg 3.75 11.24 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20059 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 132.95 mmHg 3.01 6.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20058 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 17 98.17 mmHg 3.27 13.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20064 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 17 96.27 mmHg 2.31 9.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20065 381
SS-Chr 2BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 12 125.67 mmHg 3.56 12.34 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 20067 381
Crl:CD(SD) absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 9.47 mmHg 2.86 7.57 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20107 381
Hsd:SD absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 1 16.06 mmHg vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20103 381
WKY/NCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 18.83 mmHg 3.45 10.9 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20110 381
LEW/Crl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 18 21.82 mmHg 1.81 7.7 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20109 381
F344/DuCrl absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 10 13.64 mmHg 3.25 10.27 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20111 381
WKY/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 129.58 mmHg 3.54 8.67 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20129 381
LEW/Crl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 18 118.79 mmHg 1.91 8.1 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 20136 381
FHH/EurMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 119.31 mmHg 7.58 20.05 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19520 381
SS-Chr 16BN/Mcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 121.82 mmHg 1.31 3.2 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19519 381
WKY/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 14 353.66 beats/min 12.59 47.13 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19537 381
WKY/NCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 15 367.53 beats/min 15.04 58.24 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19545 381
LE/BluGill heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 362.96 beats/min 12.38 37.13 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 19547 381
WKY/NCrl mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 132.45 mmHg 5.38 12.04 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 17597 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 3 440.07 beats/min 15.16 26.27 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17664 381
GH/OmrMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 436.85 beats/min 16.63 40.73 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 17669 381
FHH/EurMcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 381.52 beats/min 4.16 5.88 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17739 381
SS-Chr 7BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 383.32 beats/min 6.77 17.91 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17745 381
SHR/NCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 418.75 beats/min 9.1 31.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17753 381
FHH-Chr 1BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 12 439.05 beats/min 5.79 20.07 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17758 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 120.53 mmHg 4.49 12.69 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17762 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 127.12 mmHg 2.33 5.2 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17764 381
SS/JrHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 22 136.46 mmHg 2.42 11.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17763 381
SS-Chr 9BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 138.76 mmHg 4.34 11.49 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17768 381
BN/NHsdMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 114.18 mmHg 3.76 6.51 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17778 381
Hsd:SD absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 86.45 beats/min 20.26 57.3 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 17966 381
Crl:CD(SD) heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 323.57 beats/min 6.64 18.79 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18081 381
LE/BluGill heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 321.43 beats/min 4.85 12.84 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18084 381
F344/DuCrl heart rate controlled air carbon dioxide content (7 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 373.96 beats/min 15.04 36.84 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18087 381
SS-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 467.49 beats/min 17.12 41.93 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18100 381
SS-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 444.03 beats/min 9.59 25.39 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18106 381
BN/NHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 349.4 beats/min 28.52 57.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18108 381
SHR/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 4 366.99 beats/min 23.28 46.55 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18111 381
SS.BN-(D13Rat7-D13Rat127)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 173.0 mmHg 5.4 18.71 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65162 15
SS.BN-(D13Rat20-D13Got22)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 184.0 mmHg 6.2 21.48 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65165 15
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 70.19 beats/min 25.96 44.96 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18349 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 121.87 beats/min 16.48 46.61 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18351 381
SS-Chr 16BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 82.3 beats/min 21.26 56.25 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18354 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 80.45 beats/min 20.55 54.37 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18360 381
SHR/NCrl absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 101.25 beats/min 10.51 33.22 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18364 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 3 92.09 beats/min 13.91 24.09 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18366 381
LEW/Crl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 14 404.07 beats/min 15.2 56.89 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18386 381
Crl:CD(SD) heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 394.41 beats/min 15.1 42.71 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18387 381
LEW/Crl heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 370.67 beats/min 13.22 43.84 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18391 381
F344/DuCrl heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 6 408.27 beats/min 15.17 37.15 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18393 381
WKY/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 115.25 mmHg 7.93 25.08 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18762 381
LEW/Crl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 104.01 mmHg 4.13 13.71 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18769 381
Crl:CD(SD) mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 118.32 mmHg 6.53 18.47 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18767 381
F344/DuCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 119.63 mmHg 7.87 19.28 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18771 381
Crl:CD(SD) mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 116.18 mmHg 4.97 12.18 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18776 381
F344/DuCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 108.17 mmHg 2.41 8.0 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18777 381
F344/DuCrl mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 12 103.7 mmHg 3.25 11.26 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18782 381
LEW/Crl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 497.72 beats/min 9.87 22.07 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18794 381
LEW/Crl heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 506.49 beats/min 8.34 20.43 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 18796 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 16 125.53 mmHg 2.12 8.48 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18929 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 6 118.28 mmHg 5.94 14.56 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18930 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 117.67 mmHg 1.95 4.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18934 381
SS.BN-(D12Arb13-D12Rat79)/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 15 122.22 mmHg 3.42 13.23 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18935 381
SS-Chr 18BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 13 123.96 mmHg 4.3 15.52 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18943 381
SS-Chr 7BN/Mcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 147.29 mmHg 4.51 11.93 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18946 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 4 144.71 mmHg 3.21 6.42 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 18947 381
Hsd:SD heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 9 582.27 beats/min 13.01 39.02 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 18983 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 3 123.11 mmHg 12.75 22.09 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19004 381
FHH/EurMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 2 141.75 mmHg 6.42 9.07 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19008 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 182.23 mmHg 5.95 13.31 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 19010 381
SS-Chr 9BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 423.86 beats/min 17.23 48.72 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17481 381
FHH-Chr 6BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 1 309.1 beats/min vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17483 381
FHH-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 411.34 beats/min 11.45 37.98 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17487 381
FHH-Chr 17BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 8 418.05 beats/min 9.42 26.66 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17497 381
FHH-Chr 16BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 9 443.8 beats/min 11.46 34.39 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17502 381
SS-Chr 5BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 2 369.86 beats/min 16.67 23.57 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17501 381
FHH-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 358.54 beats/min 27.09 60.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17516 381
SS-Chr 11BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 350.62 beats/min 18.91 50.03 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17523 381
FHH-Chr 18BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 403.49 beats/min 13.9 43.95 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17522 381
SS-Chr 20BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 399.15 beats/min 15.47 51.32 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17521 381
SS-Chr 13BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 8 417.99 beats/min 12.93 36.58 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17525 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 61 412.19 beats/min 6.25 48.79 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17529 381
SS/JrHsdMcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 10 452.93 beats/min 8.97 28.36 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17534 381
SS-Chr 12BN/Mcwi heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 465.07 beats/min 23.98 53.62 vascular fluid filled catheter Moms and pups used in studies were fed Teklad 17539 381
SS/JrHsdMcwi mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 11 131.45 mmHg 3.35 11.1 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19514 381
SS.BN-(D13Rat111-D13Rat127)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 169.0 mmHg 2.7 9.35 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65166 15
SHR/NCrl mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 7 125.34 mmHg 3.44 9.11 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 19517 381
SS.BN-(D13Rat127-D13Rat77)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 167.0 mmHg 5.0 17.32 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65183 15
SS.BN-(D13Rat101-D13Rat46)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 153.0 mmHg 3.5 12.12 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65186 15
SS.BN-(D13Rat101-D13Rat46)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait female 86.0 days-89.0 days 12 149.0 mmHg 3.7 12.82 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65187 15
SS.BN-(D13Got51-D13Rat192)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 182.0 mmHg 6.3 21.82 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65193 15
SS.BN-(D13Rat183-D13Rat192)/Mcwi mean arterial blood pressure controlled sodium content diet (8 %) (between 16 and 19 days) Moreno et al. Physiol Genomics 2007 Oct 22;31(2):228-35. Epub 2007 Jun 12. arterial blood pressure trait male 86.0 days-89.0 days 12 191.0 mmHg 4.1 14.2 vascular fluid filled catheter left femoral artery 14400 on 3 consecutive days 65197 15
SS-Chr 18BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 5 433.81 beats/min 6.18 13.81 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18193 381
SHR/NCrl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 464.41 beats/min 10.76 28.46 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18197 381
SS-Chr 18BN/Mcwi heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 473.2 beats/min 9.8 25.93 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 18198 381
SS-Chr 16BN/Mcwi mean arterial blood pressure resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 8 117.52 mmHg 2.79 7.89 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20396 381
FHH/EurMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 120.57 beats/min 13.12 29.34 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20423 381
SS-Chr 18BN/Mcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 75.02 beats/min 9.18 24.28 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20426 381
BN/NHsdMcwi absolute change in heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 5 84.63 beats/min 13.79 30.84 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20430 381
SS-Chr 18BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 7 474.64 beats/min 8.45 22.35 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20438 381
SS-Chr 16BN/Mcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 7 413.34 beats/min 11.28 29.85 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20439 381
SS-Chr 16BN/Mcwi heart rate resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 6 598.33 beats/min 12.83 31.42 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 20531 381
Hsd:SD mean arterial blood pressure control condition PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 10 114.87 mmHg 5.69 17.99 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 16117 381
WKY/NCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 14 350.04 beats/min 18.22 68.19 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16121 381
LEW/Crl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 16 372.75 beats/min 13.56 54.23 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16123 381
F344/DuCrl heart rate controlled air oxygen content (12 %) (for 0.1 hours) PhysGen Respiratory data heart pumping trait female 82.0 days-99.0 days 11 407.25 beats/min 7.98 26.46 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16130 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 5 9.97 mmHg 1.64 3.66 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16255 381
SS/JrHsdMcwi heart rate control condition PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 411.41 beats/min 9.43 31.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16351 381
LE/BluGill heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 11 381.2 beats/min 6.78 22.49 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16437 381
LEW/Crl heart rate resting on treadmill (between 0.1 and 0.1 hours) PhysGen Respiratory data heart pumping trait male 82.0 days-99.0 days 18 370.43 beats/min 5.62 23.84 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 16434 381
SS-Chr 16BN/Mcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 13.7 mmHg 2.47 6.04 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16780 381
FHH/EurMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 7 3.26 mmHg 3.49 9.24 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16781 381
BN/NHsdMcwi absolute change in mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait female 82.0 days-99.0 days 5 11.57 mmHg 5.5 12.29 vascular fluid filled catheter Moms and pups used in studies were fed Dyets 16783 381
Hsd:SD mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (for 0.1 hours) then running on treadmill (1.6 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 116.18 mmHg 4.56 11.16 vascular fluid filled catheter Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 17458 381
GH/OmrMcwi mean arterial blood pressure resting on treadmill (for 0.1 hours) then walking on treadmill (0.8 m/min) (between 0.1 and 0.1 hours) PhysGen Respiratory data arterial blood pressure trait male 82.0 days-99.0 days 6 177.33 mmHg 3.34 8.19 vascular fluid filled catheter Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 16030 381
SR/NEisSlc mean arterial blood pressure controlled sodium content diet (8 %) (for 28 days) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. arterial blood pressure trait male 63.0 days-70.0 days 6 100.0 mmHg 1.0 2.45 vascular fluid filled catheter 0.0 102367 2687
SS/NEisSlc percent change in heart rate controlled sodium content diet (0.3 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 7 -2.0 % 0.7 1.85 vascular fluid filled catheter 0.0 102380 2687
SR/NEisSlc percent change in heart rate controlled sodium content diet (8 %) (for 28 days) then tempol (4 mol/l) (between 0 and 0 hours) Fujita M, et al., Hypertension. 2007 Aug;50(2):360-7. Epub 2007 Jun 18. heart pumping trait male 63.0 days-70.0 days 6 -3.0 % 1.9 4.65 vascular fluid filled catheter 0.0 102383 2687
SR/JrHsd mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (for 14 days) then bilateral ovariectomy then 17 beta-estradiol (10 ug/d) (for 14 days) Zheng W, et al., Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1508-13. doi: 10.1152/ajpheart.01322.2007. Epub 2008 Feb 1. arterial blood pressure trait female  days 112.0 mmHg 5.0 vascular fluid filled catheter 0.0 102209 2681
LH/Mav systolic blood pressure control condition (between 147 and 154 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 6 2hr mean (10a-12p) continuous mean 175.0 mmHg 1.0 2.45 vascular fluid filled catheter 0.0 103436 2825
LH/Mav diastolic blood pressure controlled losartan content drinking water (10 mg/kg/d) (for 63 days) Bertram D, et al., Am J Physiol Regul Integr Comp Physiol. 2002 Nov;283(5):R1041-5. doi: 10.1152/ajpregu.00620.2001. arterial blood pressure trait male 147.0 days-154.0 days 5 2hr mean (10a-12p) continuous mean 111.0 mmHg 3.0 6.71 vascular fluid filled catheter 0.0 103441 2825
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then quinapril (2 mg/kg/d) (for 14 days) and icatibant (0.4 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 11 134.0 mmHg 8.0 26.53 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100017 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then icatibant (0.4 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 11 137.0 mmHg 5.0 16.58 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100020 2398
Crl:WI(WU) mean arterial blood pressure abdominal aorta constriction then losartan (3 mg/kg/d) (for 14 days) and icatibant (0.4 mg/kg/d) (for 14 days) Goetz RM and Holtz J, Clin Sci (Lond). 1999 Aug;97(2):165-74. arterial blood pressure trait male 91.0 days 10 106.0 mmHg 5.0 15.81 vascular fluid filled catheter 0.0 aorta coarctation 35 days 100027 2398
SD-Nfe2l2em1Mcwi+/+ mean arterial blood pressure controlled sodium chloride content diet (0.4 %) (between 70 and 84 days) then controlled sodium chloride content diet (4 %) (for 3 days) then 0.9% sodium chloride solution (for 3 days) Priestley JR, et al., Am J Physiol Heart Circ Physiol. 2016 Feb 15;310(4):H478-87. doi: 10.1152/ajpheart.00586.2015. Epub 2015 Dec 4. arterial blood pressure trait male 62.0 days-76.0 days 4 95.0 mmHg 3.9 7.8 vascular fluid filled catheter 0.0 100739 2520
LH/Mav mean arterial blood pressure bilateral renal denervation and bilateral adrenalectomy then aldosterone (66 ng/kg/min) (for 1.5 hours) and hydrocortisone (33 ng/kg/min) (for 1.5 hours) and norepinephrine (333 ng/kg/min) (for 1.5 hours) and argipressin (0.17 ng/kg/min) (for 1.5 hours) Miao CY, et al., J Hypertens. 2005 Jun;23(6):1225-31. arterial blood pressure trait male 35.0 days 9 94.0 mmHg 2.0 6.0 vascular fluid filled catheter 0.0 104571 2970
MHS mean arterial blood pressure control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 84.0 days 4 133.7 mmHg 2.25 4.5 vascular fluid filled catheter trunk of common carotid artery 0.0 104101 2907
MNS mean arterial blood pressure control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 84.0 days 4 95.6 mmHg 1.2 2.4 vascular fluid filled catheter trunk of common carotid artery 0.0 104100 2907
MNS mean arterial blood pressure control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 168.0 days 6 94.9 mmHg 1.43 3.5 vascular fluid filled catheter trunk of common carotid artery 0.0 104102 2907
MHS mean arterial blood pressure streptozotocin (55 ml/kg) then insulin (4 IU/kg) (for 84 days) Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 168.0 days 6 138.1 mmHg 4.78 11.7 vascular fluid filled catheter trunk of common carotid artery 0.0 104105 2907
MHS mean arterial blood pressure control condition Pugliese G, et al., Kidney Int. 2005 Apr;67(4):1440-52. doi: 10.1111/j.1523-1755.2005.00221.x. arterial blood pressure trait male 252.0 days 6 140.5 mmHg 1.63 4.0 vascular fluid filled catheter trunk of common carotid artery 0.0 104108 2907
MHS mean arterial blood pressure control condition Capasso G, et al., Am J Physiol Renal Physiol. 2005 Jun;288(6):F1173-82. doi: 10.1152/ajprenal.00228.2004. Epub 2005 Feb 1. arterial blood pressure trait not specified 23.0 days-25.0 days 11 97.4 mmHg 1.4 4.64 vascular fluid filled catheter 0.0 104161 2926
SS-Chr 13BN/McwiCrl heart rate controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then candesartan (0.5 ug/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait male 77.0 days-98.0 days 4 409.0 beats/min 7.0 14.0 vascular fluid filled catheter femoral artery 600.0 106780 2685
SS/JrHsdMcwi heart rate monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. heart pumping trait male 56.0 days 8 340.0 beats/min 7.65 21.64 vascular fluid filled catheter 0.0 106800 3032
SS-Sod3m1Mcwi diastolic blood pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 9 86.3 mmHg 4.02 12.06 vascular fluid filled catheter 0.0 106809 3032
SS-Sod3m1Mcwi mean aortic pressure monocrotaline (40 mg/kg) Xu D, et al., Hypertension. 2011 Aug;58(2):303-9. doi: 10.1161/HYPERTENSIONAHA.110.166819. Epub 2011 Jul 5. arterial blood pressure trait male 56.0 days 9 93.9 mmHg 3.89 11.67 vascular fluid filled catheter 0.0 Mean aortic pressure 106813 3032
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (8 %) (between 28 and 42 days) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 4 MAP=.33(SP-DP) + DP 153.0 mmHg 8.0 16.0 vascular fluid filled catheter femoral artery 600.0 106758 2685
SS/HsdMcwiCrl mean arterial blood pressure controlled sodium chloride content diet (0.1 %) (between 28 and 42 days) then 2% dimethyl sulfoxide in artificial cerebrospinal fluid (300 nl/min) (for 0.2 hours) then kynurenate (0.14 ug/min) (for 0.2 hours) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. arterial blood pressure trait male 77.0 days-98.0 days 5 MAP=.33(SP-DP) + DP 110.0 mmHg 2.0 4.47 vascular fluid filled catheter femoral artery 600.0 106764 2685
COP/OlaHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 121.0 mmHg 3.0 9.49 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107331 3077
SHR/NHsd mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 173.0 mmHg 6.0 18.97 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107338 3077
BN/Crl mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 10 120.0 mmHg 3.0 9.49 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107339 3077
Crl:SD mean arterial blood pressure arterial catheter implantation (for 1 days) Klemcke HG, etal., Shock. 2008 Jun;29(6):748-53. arterial blood pressure trait male 89.0 days-95.0 days 11 115.0 mmHg 3.0 9.95 vascular fluid filled catheter 300.0 5-second intervals Initial MAP 107340 3077
WKY/NCrl absolute change in heart rate artificial cerebrospinal fluid (200 nl) then angiotensin II (90 ng) then candesartan (0.5 ug) (for 0.2 hours) then angiotensin II (90 ng) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait not specified  days 4 11.0 beats/min 7.0 14.0 vascular fluid filled catheter 0.0 110137 2685
WKY/NCrl absolute change in heart rate artificial cerebrospinal fluid (200 nl) then angiotensin II (90 ng) then candesartan (0.05 ug) (for 0.2 hours) then angiotensin II (90 ng) Gabor A and Leenen FH, Brain Res. 2012 Apr 4;1447:28-37. doi: 10.1016/j.brainres.2012.01.060. Epub 2012 Feb 1. heart pumping trait not specified  days 3 31.0 beats/min 11.0 19.05 vascular fluid filled catheter 0.0 110136 2685