| LH/Mav |
heart left ventricle weight to body weight ratio |
controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
heart left ventricle mass |
male |
119.0 days
| 7 |
2.48 |
mg/g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
103409 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 6 |
7.22 |
g/kg |
0.34 |
0.83 |
post excision weight measurement |
0.0 |
|
103422 |
2824 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112.0 days
| 8 |
24.4 |
mg/g |
0.4 |
1.13 |
post excision weight measurement |
0.0 |
|
102682 |
2703 |
| LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112.0 days
| 11 |
10.1 |
mg/100g |
0.2 |
0.66 |
post excision weight measurement |
0.0 |
|
102690 |
2703 |
| LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112.0 days
| 7 |
12.5 |
mg/100g |
0.5 |
1.32 |
post excision weight measurement |
0.0 |
|
102691 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 7 |
8.05 |
g/kg |
0.24 |
0.63 |
post excision weight measurement |
0.0 |
|
102697 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 11 |
6.24 |
g/kg |
0.07 |
0.23 |
post excision weight measurement |
0.0 |
|
102764 |
2721 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 7 |
6.81 |
g/kg |
0.19 |
0.5 |
post excision weight measurement |
0.0 |
|
103419 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
aorta mass |
male |
112.0 days
| 14 |
13.1 |
mg/100g |
0.1 |
0.37 |
post excision weight measurement |
0.0 |
|
102773 |
2721 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
heart left ventricle mass |
male |
119.0 days
| 6 |
2.88 |
mg/g |
0.06 |
0.15 |
post excision weight measurement |
0.0 |
|
103412 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
aorta mass |
male |
119.0 days
| 7 |
13.3 |
mg/100g |
0.6 |
1.59 |
post excision weight measurement |
0.0 |
|
103414 |
2824 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
heart left ventricle mass |
male |
119.0 days
| 8 |
2.41 |
mg/g |
0.08 |
0.23 |
post excision weight measurement |
0.0 |
|
103410 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
aorta mass |
male |
119.0 days
| 8 |
12.5 |
mg/100g |
0.6 |
1.7 |
post excision weight measurement |
0.0 |
|
103415 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
aorta mass |
male |
119.0 days
| 8 |
13.6 |
mg/100g |
0.5 |
1.41 |
post excision weight measurement |
0.0 |
|
103416 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
6.22 |
g/kg |
0.21 |
0.59 |
post excision weight measurement |
0.0 |
|
103420 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
5.87 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
|
103421 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 7 |
7.3 |
g/kg |
0.09 |
0.24 |
post excision weight measurement |
0.0 |
|
103423 |
2824 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
control condition (for 0 hours) |
Cerutti C, et al., Physiol Genomics. 2006 Nov 27;27(3):295-308. doi: 10.1152/physiolgenomics.00318.2005. Epub 2006 Aug 1. |
heart left ventricle mass |
male |
84.0 days
| 5 |
2.43 |
mg/g |
0.08 |
0.18 |
post excision weight measurement |
0.0 |
|
103485 |
2826 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112.0 days
| 11 |
19.9 |
mg/g |
0.5 |
1.66 |
post excision weight measurement |
0.0 |
|
102684 |
2703 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112.0 days
| 7 |
24.2 |
mg/g |
0.3 |
0.79 |
post excision weight measurement |
0.0 |
|
102685 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 9 |
7.02 |
g/kg |
0.18 |
0.54 |
post excision weight measurement |
0.0 |
|
102695 |
2703 |
| LH/Mav |
aorta weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
aorta mass |
male |
112.0 days
| 11 |
13.5 |
mg/100g |
0.2 |
0.66 |
post excision weight measurement |
0.0 |
|
102772 |
2721 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
heart left ventricle mass |
male |
119.0 days
| 8 |
2.37 |
mg/g |
0.07 |
0.2 |
post excision weight measurement |
0.0 |
|
103411 |
2824 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
heart left ventricle mass |
male |
119.0 days
| 7 |
2.79 |
mg/g |
0.04 |
0.11 |
post excision weight measurement |
0.0 |
|
103413 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
aorta mass |
male |
119.0 days
| 6 |
15.7 |
mg/100g |
0.8 |
1.96 |
post excision weight measurement |
0.0 |
|
103417 |
2824 |
| LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112.0 days
| 8 |
13.5 |
mg/100g |
0.5 |
1.41 |
post excision weight measurement |
0.0 |
|
102688 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 14 |
6.65 |
g/kg |
0.08 |
0.3 |
post excision weight measurement |
0.0 |
|
102765 |
2721 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
heart left ventricle mass |
male |
112.0 days
| 11 |
2.24 |
mg/g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
102768 |
2721 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
heart left ventricle mass |
male |
112.0 days
| 14 |
2.25 |
mg/g |
0.0 |
0.01 |
post excision weight measurement |
0.0 |
|
102769 |
2721 |
| LH/Mav |
aorta weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
aorta mass |
male |
119.0 days
| 7 |
15.8 |
mg/100g |
0.8 |
2.12 |
post excision weight measurement |
0.0 |
|
103418 |
2824 |
| LH/Mav |
heart left ventricle weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
heart left ventricle mass |
male |
112.0 days
| 9 |
23.8 |
mg/g |
0.8 |
2.4 |
post excision weight measurement |
0.0 |
|
102683 |
2703 |
| LH/Mav |
aorta weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
aorta mass |
male |
112.0 days
| 9 |
12.3 |
mg/100g |
0.4 |
1.2 |
post excision weight measurement |
0.0 |
|
102689 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 8 |
6.95 |
g/kg |
0.23 |
0.65 |
post excision weight measurement |
0.0 |
|
102694 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 11 |
6.44 |
g/kg |
0.14 |
0.46 |
post excision weight measurement |
0.0 |
|
102696 |
2703 |