Phenominer Database Results (6 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
Crl:CD(SD) plasma AMG-8718 level area under curve (AUC) AMG-8718 (600 mg/kg) (for 4 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. blood enzyme inhibitor amount male 59.0 days-66.0 days 5 549000.0 ng/ml/h 59479.41 133000.0 liquid chromatography-mass spectrometry 0.0 samples at 0.5, 1.5, 5, 10, 24 hours auc 105427 3016
Crl:CD(SD) plasma AMG-8718 level area under curve (AUC) AMG-8718 (600 mg/kg) (for 24 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. blood enzyme inhibitor amount male 81.0 days-88.0 days 5 671000.0 ng/ml/h 84076.16 188000.0 liquid chromatography-mass spectrometry 0.0 samples at 0.5, 1.5, 5, 10, 24 hours auc 105433 3016
Crl:CD(SD) plasma AMG-8718 level area under curve (AUC) AMG-8718 (10 mg/kg) (for 4 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. blood enzyme inhibitor amount male 59.0 days-66.0 days 5 15900.0 ng/ml/h 1507.11 3370.0 liquid chromatography-mass spectrometry 0.0 samples at 0.5, 1.5, 5, 10, 24 hours auc 105425 3016
Crl:CD(SD) plasma AMG-8718 level area under curve (AUC) AMG-8718 (10 mg/kg) (for 24 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. blood enzyme inhibitor amount male 81.0 days-88.0 days 5 21800.0 ng/ml/h 2710.11 6060.0 liquid chromatography-mass spectrometry 0.0 samples at 0.5, 1.5, 5, 10, 24 hours auc 105431 3016
Crl:CD(SD) plasma AMG-8718 level area under curve (AUC) AMG-8718 (100 mg/kg) (for 24 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. blood enzyme inhibitor amount male 81.0 days-88.0 days 5 217000.0 ng/ml/h 10107.03 22600.0 liquid chromatography-mass spectrometry 0.0 samples at 0.5, 1.5, 5, 10, 24 hours auc 105432 3016
Crl:CD(SD) plasma AMG-8718 level area under curve (AUC) AMG-8718 (100 mg/kg) (for 4 days) Fielden MR, et al., Toxicol Pathol. 2015 Jun;43(4):581-92. doi: 10.1177/0192623314553804. Epub 2014 Oct 31. blood enzyme inhibitor amount male 59.0 days-66.0 days 5 221000.0 ng/ml/h 15831.36 35400.0 liquid chromatography-mass spectrometry 0.0 samples at 0.5, 1.5, 5, 10, 24 hours auc 105426 3016