Phenominer Database Results (94 results)

 

Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Clinical Measurement Notes Record ID Study ID
SS.SR-(D7Mco19-D7Mco7)/Jr heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. heart left ventricle end-diastolic diameter male 109 days-112 days 4 8.6 mm 0.4 0.8 transthoracic echocardiography 0 0 65744 283
SS/JrSeac heart left ventricle end-diastolic diameter controlled sodium content diet (8 %) (for 35 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. heart left ventricle end-diastolic diameter not specified 77 days 5 5.26 mm 0.49 1.1 transthoracic echocardiography 0.0 0 68580 733
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 252 days 6 7.83 mm 0.3 0.73 echocardiography 0.0 0 99581 2319
SR heart left ventricle end-diastolic diameter controlled sodium content diet (6 %) (between 56 and 70 days) then pentobarbital (50 mg/kg) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. heart left ventricle end-diastolic diameter male 98 days-132 days 7 5.8 mm 0.42 1.1 transthoracic echocardiography 0.0 0 103370 2804
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.1 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 2 days 98847 2160
SD heart left ventricle end-diastolic diameter sham surgical control condition (between 120 and 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.1 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 sham ACF 5 days 98849 2160
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 84 days 7 7.52 mm 0.32 0.85 echocardiography 0.0 0 99768 2319
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 84 days 6 8.33 mm 0.4 0.98 echocardiography 0.0 0 99769 2319
SS.ZUC-Leprfa-/-/Slc heart left ventricle end-diastolic diameter bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 8 7.2 mm 0.14 0.4 echocardiography 0.0 ovariectomy 42 days 101717 2622
WKY heart left ventricle end-diastolic diameter left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 266 days-280 days 16 10.8 mm 0.3 1.2 echocardiography 0.0 lad occlusion 210 days 100307 2460
SS-Adora2bem2Mcwi heart left ventricle end-diastolic diameter isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 147 days 10 7.68 mm 0.12 0.38 transthoracic echocardiography 0.0 0 should be inner diameter 105799 3023
SS/JrHsdMcwi heart left ventricle end-diastolic diameter angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 63 days-70 days 5 6.63 mm 0.37 0.83 transthoracic echocardiography 0.0 0 should be inner diameter 105822 3023
SS.LEW-(D16Chm36-D16Mit2)/Ayd heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 18 7.75 mm 0.17 0.74 transthoracic echocardiography 0.0 0 68269 542
SR heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart left ventricle end-diastolic diameter male 126 days 6 7.3 mm 0.24 0.6 transthoracic echocardiography 0.0 0 103311 2803
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 7.0 mm 0.1 0.22 echocardiography 0.0 sham ACF 2 days 99341 2278
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 8 10.6 mm 0.3 0.85 echocardiography 0.0 ACF 28 days 99344 2278
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 168 days 7 8.68 mm 0.33 0.87 echocardiography 0.0 0 99770 2319
WKY heart left ventricle end-diastolic diameter left anterior descending coronary artery occlusion (for 224 days) then furosemide (10 mg/kg/d) (for 161 days) then ramipril (1 mg/kg/d) (for 182 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 266 days-280 days 32 10.6 mm 0.3 1.7 echocardiography 0.0 lad occlusion 210 days 100308 2460
SS/JrSeac heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 84 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. heart left ventricle end-diastolic diameter not specified 126 days 5 6.3 mm 0.25 0.57 transthoracic echocardiography 0.0 0 68581 733
SS.LEW-(D18Chm41-D18Rat92)/Ayd heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 8 7.36 mm 0.1 0.27 transthoracic echocardiography 0.0 0 68268 542
SS/NEisSlc heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. heart left ventricle end-diastolic diameter male 126 days 8 8.7 mm 0.3 0.85 transthoracic echocardiography 0.0 0 102320 2684
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 28 days 7 5.3 mm 0.49 1.3 echocardiography 0.0 0 99574 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 168 days 5 8.48 mm 0.08 0.18 echocardiography 0.0 0 99579 2319
SR heart left ventricle end-diastolic diameter controlled sodium content diet (6 %) (between 35 and 49 days) then pentobarbital (50 mg/kg) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. heart left ventricle end-diastolic diameter male 77 days-91 days 7 6.0 mm 0.26 0.7 transthoracic echocardiography 0.0 0 103369 2804
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter control condition (for 168 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 168 days 5 8.84 mm 0.09 0.2 echocardiography 0.0 0 99580 2319
SS.ZUC-Leprfa-/-/Slc heart left ventricle end-diastolic diameter control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 7 7.58 mm 0.2 0.53 echocardiography 0.0 0 101789 2641
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 98 days 4 8.75 mm 0.66 1.32 echocardiography 0.0 0 99712 2319
SS.ZUC-Leprfa-/-/Slc heart left ventricle end-diastolic diameter atorvastatin (6 mg/kg/d) (for 28 days) Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. heart left ventricle end-diastolic diameter male 91 days 13 8.56 mm 0.08 0.29 echocardiography 0.0 0 101996 2644
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.4 mm 0.3 0.73 HP Sonos 5500 echo ultrasound 1.0 ACF 360 min 98842 2160
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.8 mm 0.4 0.98 HP Sonos 5500 echo ultrasound 1.0 ACF 720 min 98844 2160
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 175 days 10 11.6 mm 0.4 1.26 echocardiography 0.0 ACF 105 days 99238 2278
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 8 10.2 mm 0.2 0.57 echocardiography 0.0 ACF 28 days 99346 2278
WKY heart left ventricle end-diastolic diameter sham surgical control condition (for 196 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 238 days-252 days 12 8.3 mm 0.2 0.69 echocardiography 0.0 lad occlusion sham 196 days 100339 2460
SS/Jr heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 40 7.18 mm 0.09 0.57 transthoracic echocardiography 0.0 0 68266 542
SS/JrHsdMcwi heart left ventricle end-diastolic diameter isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 147 days 10 7.8 mm 0.14 0.44 transthoracic echocardiography 0.0 0 should be inner diameter 105798 3023
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle end-diastolic diameter female 252 days 4 7.28 mm 0.11 0.22 echocardiography 0.0 0 101643 2621
SS.SR-(D3Arb14-D3Mco36)/Mco heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. heart left ventricle end-diastolic diameter male 109 days-112 days 7 7.3 mm 0.4 1.06 transthoracic echocardiography 0 0 65742 283
SS.LEW-(D3Rat52-D3Chm57)/Ayd heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 8 6.94 mm 0.23 0.65 transthoracic echocardiography 0.0 0 68272 542
SR/NEisSlc heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. heart left ventricle end-diastolic diameter male 126 days 8 6.5 mm 0.1 0.28 transthoracic echocardiography 0.0 0 102319 2684
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 28 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 28 days 5 5.7 mm 0.36 0.8 echocardiography 0.0 0 99573 2319
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 56 days 6 8.18 mm 0.35 0.86 echocardiography 0.0 0 99576 2319
SS.ZUC-Leprfa-/-/Slc heart left ventricle end-diastolic diameter everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 12 8.05 mm 0.07 0.24 echocardiography 0.0 0 101790 2641
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 6 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.2 mm 0.3 0.73 HP Sonos 5500 echo ultrasound 1.0 sham ACF 360 min 98843 2160
SS.ZUC-Leprfa-/-/Slc heart left ventricle end-diastolic diameter bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 7 7.1 mm 0.12 0.32 echocardiography 0.0 ovariectomy 42 days 101718 2622
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 8 7.0 mm 0.2 0.57 echocardiography 0.0 sham ACF 28 days 99235 2278
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 105 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 175 days 10 9.0 mm 0.1 0.32 echocardiography 0.0 sham ACF 105 days 99237 2278
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 2 days) then Aprotinin (12000 kIU) (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 8.0 mm 0.1 0.22 echocardiography 0.0 ACF 2 days 99342 2278
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 7 7.7 mm 0.2 0.53 echocardiography 0.0 sham ACF 28 days 99343 2278
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 28 days) then Aprotinin (12000 kIU) (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 7 7.6 mm 0.1 0.26 echocardiography 0.0 sham ACF 28 days 99345 2278
WKY heart left ventricle end-diastolic diameter left anterior descending coronary artery occlusion (for 196 days) then furosemide (10 ml/kg/d) (for 182 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 238 days-252 days 20 10.6 mm 0.2 0.89 echocardiography 0.0 lad occlusion 196 days 100340 2460
SS-Adora2bem2Mcwi heart left ventricle end-diastolic diameter isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 49 days-56 days 7 7.12 mm 0.22 0.58 transthoracic echocardiography 0.0 0 should be inner diameter 105821 3023
SS-Adora2bem2Mcwi heart left ventricle end-diastolic diameter angiotensin II (200 ng/kg/min) (for 14 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 63 days-70 days 7 6.73 mm 0.18 0.48 transthoracic echocardiography 0.0 0 should be inner diameter 105823 3023
SS/JrHsdMcwi heart left ventricle end-diastolic diameter angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 77 days-84 days 5 7.15 mm 0.34 0.76 transthoracic echocardiography 0.0 0 should be inner diameter 105824 3023
SS.LEW-(D10Got112-Igfbp4)/Ayd heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 5 7.36 mm 0.3 0.67 transthoracic echocardiography 0.0 0 68271 542
WKY heart left ventricle end-diastolic diameter left anterior descending coronary artery occlusion (for 196 days) then vehicle control condition (for 182 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 238 days-252 days 30 10.6 mm 0.1 0.55 echocardiography 0.0 lad occlusion 196 days 100341 2460
SS.ZUC-Leprfa-/-/Slc heart left ventricle end-diastolic diameter vehicle control condition (0.5 %) (for 28 days) Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. heart left ventricle end-diastolic diameter male 91 days 13 8.27 mm 0.13 0.47 echocardiography 0.0 0 101995 2644
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 6.9 mm 0.2 0.45 echocardiography 0.0 sham ACF 2 days 99339 2278
SS/Jr heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. heart left ventricle end-diastolic diameter male 109 days-112 days 6 7.4 mm 0.4 0.98 transthoracic echocardiography 0 0 65741 283
LEW heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 14 7.16 mm 0.25 0.93 transthoracic echocardiography 0.0 0 heart left ventricle anterior wall thickness 68265 542
SS.LEW-(D16Rat112-D16Chm60)/Ayd heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 14 7.51 mm 0.11 0.42 transthoracic echocardiography 0.0 0 68270 542
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter control condition (for 252 days) Holditch SJ, et al., Sci Rep. 2016 May 10;6:25623. doi: 10.1038/srep25623. heart left ventricle end-diastolic diameter female 252 days 5 7.81 mm 0.06 0.13 echocardiography 0.0 0 101644 2621
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 84 days 6 7.53 mm 0.07 0.17 echocardiography 0.0 0 99577 2319
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter control condition (for 84 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 84 days 10 7.52 mm 0.32 1.01 echocardiography 0.0 0 99578 2319
SR heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart left ventricle end-diastolic diameter male 84 days 6 6.7 mm 0.33 0.8 transthoracic echocardiography 0.0 0 103309 2803
SR heart left ventricle end-diastolic diameter controlled sodium content diet (6 %) (between 21 and 28 days) then pentobarbital (50 mg/kg) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. heart left ventricle end-diastolic diameter male 63 days-70 days 7 5.7 mm 0.45 1.2 transthoracic echocardiography 0.0 0 103368 2804
SS heart left ventricle end-diastolic diameter controlled sodium content diet (6 %) (between 56 and 70 days) then pentobarbital (50 mg/kg) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. heart left ventricle end-diastolic diameter male 98 days-132 days 7 5.2 mm 0.26 0.7 transthoracic echocardiography 0.0 0 103373 2804
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter control condition Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 8 8.09 mm 0.22 0.62 echocardiography 0.0 0 101787 2641
SD heart left ventricle end-diastolic diameter sham surgical control condition (for 12 hours) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.3 mm 0.3 0.73 HP Sonos 5500 echo ultrasound 1.0 sham ACF 720 min 98845 2160
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 2 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) (for 0 hours) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 8.1 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 ACF 2 days 98846 2160
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 2 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 72 days 5 8.2 mm 0.2 0.45 echocardiography 0.0 ACF 2 days 99340 2278
SS/JrHsdMcwi heart left ventricle end-diastolic diameter isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 49 days-56 days 5 6.99 mm 0.16 0.36 transthoracic echocardiography 0.0 0 should be inner diameter 105820 3023
SS-Adora2bem2Mcwi heart left ventricle end-diastolic diameter angiotensin II (200 ng/kg/min) (for 28 days) then isoflurane (1-2 %) Nayak S, et al., Purinergic Signal. 2015 Dec;11(4):519-31. doi: 10.1007/s11302-015-9470-7. Epub 2015 Sep 18. heart left ventricle end-diastolic diameter male 77 days-84 days 7 7.06 mm 0.22 0.58 transthoracic echocardiography 0.0 0 should be inner diameter 105825 3023
SS/JrSeac heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 35 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. heart left ventricle end-diastolic diameter not specified 77 days 5 5.82 mm 0.3 0.66 transthoracic echocardiography 0.0 0 68579 733
SS/JrSeac heart left ventricle end-diastolic diameter controlled sodium content diet (8 %) (for 84 days) Fukushima K, et al., Nucl Med Biol. 2010 Nov;37(8):1005-12. Epub 2010 Sep 1. heart left ventricle end-diastolic diameter not specified 126 days 5 8.9 mm 0.93 2.07 transthoracic echocardiography 0.0 0 68582 733
SS heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 42 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart left ventricle end-diastolic diameter male 84 days 7 6.4 mm 0.34 0.9 transthoracic echocardiography 0.0 0 103308 2803
SS.LEW-(D18Rat29-D18Rat55)/Ayd heart left ventricle end-diastolic diameter controlled sodium content diet (0.2 %) (for 14 days) then controlled sodium content diet (2 %) (for 35 days) Deng AY, et al., J Hypertens. 2008 Oct;26(10):1935-1943. heart left ventricle end-diastolic diameter male 77 days 11 7.41 mm 0.14 0.46 transthoracic echocardiography 0.0 0 68267 542
SS/NEisSlc heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days) Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. heart left ventricle end-diastolic diameter male 126 days 8 7.0 mm 0.2 0.57 transthoracic echocardiography 0.0 0 102321 2684
SS heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 84 days) Fujii N, et al., Am J Physiol Heart Circ Physiol. 2004 Aug;287(2):H760-6. doi: 10.1152/ajpheart.00734.2003. Epub 2004 Mar 18. heart left ventricle end-diastolic diameter male 126 days 6 8.7 mm 0.12 0.3 transthoracic echocardiography 0.0 0 103310 2803
SS heart left ventricle end-diastolic diameter controlled sodium content diet (6 %) (between 21 and 28 days) then pentobarbital (50 mg/kg) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. heart left ventricle end-diastolic diameter male 63 days-70 days 7 6.1 mm 0.42 1.1 transthoracic echocardiography 0.0 0 103371 2804
SS heart left ventricle end-diastolic diameter controlled sodium content diet (6 %) (between 35 and 49 days) then pentobarbital (50 mg/kg) Kamei K, et al., Circ J. 2007 Mar;71(3):390-6. heart left ventricle end-diastolic diameter male 77 days-91 days 7 5.7 mm 0.42 1.1 transthoracic echocardiography 0.0 0 103372 2804
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter control condition (for 252 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 252 days 5 8.88 mm 0.22 0.49 echocardiography 0.0 0 99582 2319
SS-Nppbem2Mcwi+/+ heart left ventricle end-diastolic diameter control condition (for 56 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 56 days 5 8.11 mm 0.35 0.78 echocardiography 0.0 0 99575 2319
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter controlled sodium content diet (for 21 days) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 98 days 4 8.17 mm 0.32 0.64 echocardiography 0.0 0 99713 2319
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter everolimus (0.83 mg/kg/d) (for 28 days) Uchinaka A, et al., Pharmacol Res Perspect. 2017 Aug;5(4). doi: 10.1002/prp2.331. heart left ventricle end-diastolic diameter male 91 days 10 7.65 mm 0.12 0.38 echocardiography 0.0 0 101788 2641
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 5 days) then ketamine (80 mg/kg) (for 0 hours) and xylazine (10 mg/kg) Seqqat R, et al., J Mol Cell Cardiol. 2012 Aug;53(2):240-9. doi: 10.1016/j.yjmcc.2012.05.004. Epub 2012 May 15. heart left ventricle end-diastolic diameter male 0 days 6 7.9 mm 0.2 0.49 HP Sonos 5500 echo ultrasound 1.0 ACF 5 days 98848 2160
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 168 days 6 8.33 mm 0.64 1.57 echocardiography 0.0 0 99771 2319
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter vehicle control condition Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 252 days 7 7.99 mm 0.62 1.64 echocardiography 0.0 0 99772 2319
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter bilateral ovariectomy (for 42 days) then vehicle control condition (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 9 7.21 mm 0.21 0.63 echocardiography 0.0 ovariectomy 42 days 101715 2622
SS.ZUC-Leprfa+/+/Slc heart left ventricle end-diastolic diameter bilateral ovariectomy (for 42 days) then 17 beta-estradiol (0.5 mg) (for 35 days) Murase T, et al., Hypertension. 2012 Mar;59(3):694-704. doi: 10.1161/HYPERTENSIONAHA.111.180976. Epub 2012 Jan 23. heart left ventricle end-diastolic diameter female 91 days 12 6.5 mm 0.17 0.59 echocardiography 0.0 ovariectomy 42 days 101716 2622
SD heart left ventricle end-diastolic diameter artificial aortocaval fistula (for 28 days) Wei CC, et al., PLoS One. 2012;7(6):e40110. doi: 10.1371/journal.pone.0040110. Epub 2012 Jun 29. heart left ventricle end-diastolic diameter male 98 days 8 10.1 mm 0.3 0.85 echocardiography 0.0 ACF 28 days 99236 2278
SS.ZUC-Leprfa-/-/Slc heart left ventricle end-diastolic diameter atorvastatin (20 mg/kg/d) (for 28 days) Yamada Y, et al., Int J Cardiol. 2017 Aug 1;240:332-338. doi: 10.1016/j.ijcard.2017.04.103. Epub 2017 May 4. heart left ventricle end-diastolic diameter male 91 days 13 8.43 mm 0.11 0.4 echocardiography 0.0 0 101997 2644
SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco heart left ventricle end-diastolic diameter controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 29 days) then controlled sodium content diet (4 %) (between 40 and 41 days) Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. heart left ventricle end-diastolic diameter male 109 days-112 days 7 6.9 mm 0.2 0.53 transthoracic echocardiography 0 0 65743 283
WKY heart left ventricle end-diastolic diameter sham surgical control condition (for 224 days) Rokutan H, et al., Int J Cardiol. 2012 Sep 20;160(1):20-5. doi: 10.1016/j.ijcard.2011.03.005. Epub 2011 Mar 29. heart left ventricle end-diastolic diameter male 266 days-280 days 5 7.9 mm 0.2 0.45 echocardiography 0.0 lad occlusion sham 210 days 100306 2460
SS-Nppbem2Mcwi-/- heart left ventricle end-diastolic diameter gene transfer of the rat natriuretic peptide B gene using an adenovirus vector (100000000000 PFU) Holditch SJ, et al., Hypertension. 2015 Jul;66(1):199-210. doi: 10.1161/HYPERTENSIONAHA.115.05610. Epub 2015 May 11. heart left ventricle end-diastolic diameter male 252 days 6 8.52 mm 0.51 1.25 echocardiography 0.0 0 99773 2319