Phenominer Database Results (393 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Individual Records Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
SS-Mmp2em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 4.75 mEq/d 0.62 1.51 Download Values automated urine analysis - 66814 717
SS-Alms1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 5.14 mEq/d 1.44 3.53 Download Values automated urine analysis - 66815 717
SS-Nckap5em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 10.88 mEq/d 1.03 2.74 Download Values automated urine analysis - 66824 717
SS-Chr 5BN-Cyp4a2em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 9.13 mEq/d 0.61 1.06 Download Values automated urine analysis - 66834 717
SS-Ets1em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 7.37 mEq/d 0.72 1.44 Download Values automated urine analysis - 66840 717
SS-Apoeem7Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 9.96 mEq/d 1.32 2.95 Download Values automated urine analysis - 66841 717
SS-Nckap5em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 11.54 mEq/d 1.15 2.58 Download Values automated urine analysis - 66842 717
SS-Rag1em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 9.8 mEq/d 1.19 2.38 Download Values automated urine analysis - 66850 717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 10.68 mEq/d 0.94 1.88 Download Values automated urine analysis - 66854 717
SS-Itga9em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 9.81 mEq/d 0.91 1.82 Download Values automated urine analysis - 66862 717
SS-Gpr183em3Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 10.02 mEq/d 0.96 2.71 Download Values automated urine analysis - 66866 717
SS-Mas1em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 10.91 mEq/d 2.02 2.85 Download Values automated urine analysis - 66869 717
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 7.93 mEq/d 0.88 2.77 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51884 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 7.96 mEq/d 0.5 1.4 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51887 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 12.61 mEq/d 0.77 2.17 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51885 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 12.4 mEq/d 1.43 4.05 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52011 481
FHH-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 18.34 mEq/d 2.1 5.55 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52784 482
FHH-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 23.17 mEq/d 2.06 5.05 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52786 482
FHH-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 12.48 mEq/d 2.12 5.19 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52787 482
FHH-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 21.06 mEq/d 2.21 7.33 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52789 482
FHH-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 15.39 mEq/d 2.33 6.6 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52791 482
FHH-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 14.56 mEq/d 2.3 6.52 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52790 482
FHH-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 17.11 mEq/d 1.28 3.83 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52794 482
FHH-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 19.48 mEq/d 1.49 4.46 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52807 482
FHH-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 5 17.74 mEq/d 4.06 9.07 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52806 482
FHH-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 19.66 mEq/d 2.76 7.3 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52815 482
FHH-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 14.46 mEq/d 2.21 6.62 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52818 482
SS-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 20.45 mEq/d 2.19 5.79 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52749 482
SS-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 20 8.83 mEq/d 0.82 3.65 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52753 482
SS-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 20.07 mEq/d 2.22 6.67 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52751 482
SS-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 20 15.6 mEq/d 1.69 7.57 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52762 482
SS-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 19 10.57 mEq/d 1.46 6.38 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52765 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 13 11.79 mEq/d 0.65 2.34 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52768 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 21 12.87 mEq/d 1.17 5.34 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52774 482
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 6.59 mEq/d 0.55 1.64 Download Values flame atomic emission spectrometry 50871 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 1.16 mEq/d 0.25 0.62 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51044 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 1.74 mEq/d 0.27 0.76 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51265 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 1.46 mEq/d 0.2 0.9 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51266 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 6 1.4 mEq/d 0.14 0.34 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51267 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.32 mEq/d 0.09 0.25 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51272 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 1.62 mEq/d 0.15 0.47 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51269 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 1.21 mEq/d 0.14 0.65 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51516 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 1.17 mEq/d 0.16 0.49 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51527 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 7.87 mEq/d 1.47 4.17 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51640 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 8.01 mEq/d 0.64 2.01 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51642 481
SS/HsdMcwiCrl urine sodium excretion rate controlled carbohydrate content diet (53 %) (for 91 days) and controlled fat content diet (14 %) (for 91 days) and controlled protein content diet (33 %) (for 91 days) Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. urine sodium amount male 112.0 days 7 6.0 mEq/d 0.9 2.38 automated urine analysis 0.0 67667 735
SS-Ulk3em4Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 10.05 mEq/d 0.61 1.22 Download Values automated urine analysis - 43578 421
SS-Ulk3em4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 18 9.33 mEq/d 0.55 2.32 Download Values automated urine analysis - 43577 421
SS-Cyp1a1em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 11.07 mEq/d 0.46 1.45 Download Values automated urine analysis - 44200 441
SS-Stk39em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 6.72 mEq/d 0.88 2.15 Download Values automated urine analysis - 44199 441
SS-Cdh13em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 9.87 mEq/d 1.46 2.92 Download Values automated urine analysis - 44208 441
SS-Slc30a8em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 9.47 mEq/d 1.25 2.51 Download Values automated urine analysis - 44209 441
SS-Tcf7l2em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 10.44 mEq/d 0.84 1.88 Download Values automated urine analysis - 44213 441
SS-Plcd3em4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 13 10.84 mEq/d 0.54 1.96 Download Values automated urine analysis - 44222 441
SS-Plod1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 12 6.79 mEq/d 1.01 3.52 Download Values automated urine analysis - 44224 441
SS-Cyp1a1em5Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 10.52 mEq/d 1.21 1.71 Download Values automated urine analysis - 44230 441
SS-Mstnem3Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 10.54 mEq/d 0.88 2.48 Download Values automated urine analysis - 44232 441
SS-Sh2b3em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 11.38 mEq/d 0.34 0.96 Download Values automated urine analysis - 44238 441
SS-Plod1em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 8.04 mEq/d 1.21 2.7 Download Values automated urine analysis - 44241 441
SS-Nppbem2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 16 9.97 mEq/d 0.61 2.45 Download Values automated urine analysis - 44247 441
SS-Stk39em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 8.66 mEq/d 0.84 2.67 Download Values automated urine analysis - 44246 441
SS-Slc30a8em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 11 10.43 mEq/d 0.56 1.84 Download Values automated urine analysis - 44253 441
SS-Kcnq1em14Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 8.31 mEq/d Download Values automated urine analysis - 44256 441
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 92.0 days-94.0 days 14 0.56 mEq/d 0.06 0.21 unspecified method 0.0 urine sodium analysis umol/min 69469 151
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) then adrenomedulin (400 ng/hr) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77.0 days 14 1.7 mEq/d 0.13 0.5 automated urine sodium analysis 0.0 102470 2689
MHS urine sodium excretion rate streptozotocin (50 mg/kg) (for 147 days) then insulin (2 IU/d) (for 147 days) Ge Y, et al., Physiol Rep. 2017 Feb;5(3). pii: 5/3/e13089. doi: 10.14814/phy2.13089. urine sodium amount male 213.0 days 6 0.81 mEq/d 0.1 0.25 urine sodium analysis 0.0 104031 2886
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77.0 days 7 2.7 mEq/d 0.49 1.3 automated urine sodium analysis 0.0 102439 2689
SS/JrHsd urine sodium excretion rate gelled diet (200 g/kg/d) (for 8 days) then carbenoxolone (100 mg/kg/d) (for 6 days) Fenton RA, et al., Am J Physiol Renal Physiol. 2003 Jul;285(1):F143-51. Epub 2003 Apr 8. urine sodium amount male  days 6 0.79 mEq/d 0.08 0.2 automated urine sodium analysis 0.0 osmotic pump implant 6 days 102554 2691
WKY/NHsd urine sodium excretion rate standard rat chow (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 7 1.0 mEq/d 0.2 0.53 urine sodium analysis 0.0 mmol/d 99183 2238
WKY/NHsd urine sodium excretion rate controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then vehicle control condition (0.5 ml) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 7 41.9 mEq/d 5.2 13.76 urine sodium analysis 0.0 99185 2238
MW urine sodium excretion rate nephrectomy (for 28 days) then control condition Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. urine sodium amount male  days 7 1.39 mEq/d 0.15 0.4 flame photometry 0.0 5/6 nephrectomy 28 days 101048 2561
SHRSP/A3NCrl urine sodium excretion rate controlled sodium chloride content diet (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. urine sodium amount male 84.0 days-91.0 days 9 2.4 mEq/d 0.4 1.2 urine sodium analysis 86400.0 baseline baseline high salt high fat diet group 107063 3073
SS-Ube2q2em3Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 11.19 mEq/d Download Values automated urine analysis - 66819 717
SS-Rag1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 9.59 mEq/d 0.99 1.71 Download Values automated urine analysis - 66816 717
FHH-Chr 1BN-Sorcs1em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 7.45 mEq/d 1.84 3.19 Download Values automated urine analysis - 66822 717
SS-Bcas3em4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 5.79 mEq/d 1.3 2.25 Download Values automated urine analysis - 66827 717
SS-Tfdp2em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 13.38 mEq/d 1.65 2.86 Download Values automated urine analysis - 66825 717
SS-Apoeem7Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 12.51 mEq/d 2.26 3.92 Download Values automated urine analysis - 66836 717
SS-Gpr183em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 7.12 mEq/d 2.39 4.78 Download Values automated urine analysis - 66838 717
SS-Renem1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 7.06 mEq/d 1.41 3.15 Download Values automated urine analysis - 66863 717
SS-Chr 5BN-Cyp4a2em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 7.84 mEq/d 1.38 3.66 Download Values automated urine analysis - 66865 717
SS-Ube2q2em3Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 11.4 mEq/d 1.5 2.13 Download Values automated urine analysis - 66872 717
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 16 12.7 mEq/d 1.39 5.55 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51886 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 19 11.47 mEq/d 0.98 4.28 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51882 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 10.9 mEq/d 0.8 2.54 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51894 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 10.76 mEq/d 0.53 1.6 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52019 481
FHH-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 1 10.05 mEq/d Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52785 482
FHH-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 8 26.38 mEq/d 1.83 5.17 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52795 482
FHH-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 11.86 mEq/d 2.45 7.36 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52797 482
FHH-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 12.0 mEq/d 2.14 6.77 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52796 482
FHH-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 30.48 mEq/d 3.7 9.8 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52804 482
FHH-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 8.59 mEq/d 1.43 3.78 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52808 482
FHH-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 14.41 mEq/d 2.04 6.13 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52813 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 15.99 mEq/d 2.14 7.08 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52821 482
SS-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 9.79 mEq/d 2.32 6.96 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52739 482
SS-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 20.45 mEq/d 2.52 6.66 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52743 482
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 15.46 mEq/d 2.53 7.6 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52738 482
SS-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 16.93 mEq/d 1.84 5.21 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52744 482
SS-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 14.58 mEq/d 1.41 4.68 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52745 482
SS-Chr YBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 17 13.93 mEq/d 1.18 4.86 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52759 482
SS-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 15.25 mEq/d 2.49 6.59 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52766 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 25.2 mEq/d 2.71 8.56 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52776 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 21 15.57 mEq/d 1.26 5.76 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52777 482
FHH-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 21.01 mEq/d 1.52 4.55 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52781 482
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 10.64 mEq/d 1.12 3.17 Download Values flame atomic emission spectrometry 50872 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 6 1.16 mEq/d 0.02 0.04 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51047 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 1.46 mEq/d 0.11 0.36 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51270 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 11 0.78 mEq/d 0.1 0.33 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51271 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 12.55 mEq/d 1.2 3.38 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51298 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 4.93 mEq/d 0.54 1.53 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51295 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 5 12.15 mEq/d 0.74 1.66 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51296 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 1.82 mEq/d 0.27 0.81 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51362 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.68 mEq/d 0.25 0.74 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51364 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.3 mEq/d 0.09 0.26 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51522 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 7 0.91 mEq/d 0.11 0.28 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51519 481
SS/HsdMcwiCrl urine sodium excretion rate controlled carbohydrate content diet (69 %) (for 91 days) and controlled fat content diet (12 %) (for 91 days) and controlled protein content diet (19 %) (for 91 days) Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. urine sodium amount male 112.0 days 7 9.0 mEq/d 1.3 3.44 automated urine analysis 0.0 67669 735
SS/HsdMcwiCrl urine sodium excretion rate controlled carbohydrate content diet (69 %) (for 63 days) and controlled fat content diet (12 %) (for 63 days) and controlled protein content diet (19 %) (for 63 days) then controlled carbohydrate content diet (53 %) (for 28 days) and controlled fat content diet (14 %) (for 28 days) and controlled protein content diet (33 %) (for 28 days) Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. urine sodium amount male 112.0 days 4 5.9 mEq/d 0.4 0.8 automated urine analysis 0.0 67670 735
SS-Wdr72em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 7.72 mEq/d 1.06 2.98 Download Values automated urine analysis - 43568 421
SS-Sh2b3em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 16 10.41 mEq/d 0.37 1.48 Download Values automated urine analysis - 43567 421
SS-Adra2aem1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 8.55 mEq/d 0.59 1.68 Download Values automated urine analysis - 43569 421
SS-Ulk3em4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 8.12 mEq/d 0.22 0.31 Download Values automated urine analysis - 43575 421
SS-Hexim2em4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 7.24 mEq/d 2.13 3.69 Download Values automated urine analysis - 43576 421
SS-Prokr1em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 8.28 mEq/d 1.18 3.13 Download Values automated urine analysis - 44198 441
SS-Agtr1aem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 7.88 mEq/d 0.86 2.1 Download Values automated urine analysis - 44197 441
SS-Kcnq1em14Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 10.14 mEq/d 1.42 3.77 Download Values automated urine analysis - 44201 441
SS-Plekha7em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 7.76 mEq/d 0.97 2.37 Download Values automated urine analysis - 44202 441
SS-Msraem4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 9.26 mEq/d 1.25 3.3 Download Values automated urine analysis - 44210 441
SS-Mstnem1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 13 10.1 mEq/d 0.7 2.52 Download Values automated urine analysis - 44212 441
SS-Wdr72em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 12.63 mEq/d Download Values automated urine analysis - 44216 441
SS-Mstnem3Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 11.77 mEq/d Download Values automated urine analysis - 44220 441
SS-Plcd3em7Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 8.21 mEq/d 0.7 2.22 Download Values automated urine analysis - 44234 441
SS-Msraem3Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 10.64 mEq/d 1.7 2.41 Download Values automated urine analysis - 44237 441
SS-Wdr72em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 11.21 mEq/d 0.0 0.0 Download Values automated urine analysis - 44242 441
SS-Plcd3em4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 9.59 mEq/d 0.74 1.28 Download Values automated urine analysis - 44257 441
SD urine sodium excretion rate control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. urine sodium amount male 90.0 days 9 1.4 mEq/d 0.4 1.2 urine sodium analysis 0.0 101236 2582
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 63.0 days 7 2.1 mEq/d 0.38 1.0 automated urine sodium analysis 0.0 102435 2689
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 70.0 days 8 1.9 mEq/d 0.21 0.6 automated urine sodium analysis 0.0 102437 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 14 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 70.0 days 7 1.9 mEq/d 0.34 0.9 automated urine sodium analysis 0.0 102438 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77.0 days 8 1.2 mEq/d 0.11 0.3 automated urine sodium analysis 0.0 102440 2689
SS/JrHsd urine sodium excretion rate gelled diet (200 g/kg/d) (for 8 days) then distilled water (for 6 days) Fenton RA, et al., Am J Physiol Renal Physiol. 2003 Jul;285(1):F143-51. Epub 2003 Apr 8. urine sodium amount male  days 6 0.87 mEq/d 0.04 0.1 automated urine sodium analysis 0.0 osmotic pump implant 6 days 102553 2691
SS-Agtrapem4Mcwi-/- urine sodium excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60.0 days-69.0 days 9.3 mEq/d 1.0 urine electrolyte analysis 0.0 98449 2059
SS/Hsd urine sodium excretion rate controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60.0 days-69.0 days 10.0 mEq/d 0.6 urine electrolyte analysis 0.0 98450 2059
SS-Renem1Mcwi+/- urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine sodium amount male 56.0 days 9 0.81 mEq/d 0.08 0.24 urine sodium analysis 0.0 98326 2038
SS-Renem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine sodium amount female 56.0 days 8 0.71 mEq/d 0.08 0.23 urine sodium analysis 0.0 98328 2038
MW urine sodium excretion rate nephrectomy (for 28 days) then reserpine (5 mg/l) (for 21 days) and hydralazine (80 mg/l) (for 21 days) and controlled hydralazine content drinking water (25 mg/l) (for 21 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. urine sodium amount male  days 7 1.78 mEq/d 0.28 0.74 flame photometry 0.0 5/6 nephrectomy 28 days 101050 2561
WKY urine sodium excretion rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 9 0.33 mEq/d 0.04 0.13 urine sodium analysis 0.0 PA IV 50mg/kg 100503 2479
WKY urine sodium excretion rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 9 0.59 mEq/d 0.16 0.48 urine sodium analysis 0.0 100505 2479
SS-Ncf2em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 11.43 mEq/d 0.64 1.56 Download Values automated urine analysis - 66812 717
SS-Mthfrem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 5.1 mEq/d Download Values automated urine analysis - 66821 717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 9.75 mEq/d 0.22 0.31 Download Values automated urine analysis - 66833 717
SS-Nox4em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 6.15 mEq/d 0.31 0.54 Download Values automated urine analysis - 66844 717
SS-Mmp2em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 8.0 mEq/d 1.33 3.26 Download Values automated urine analysis - 66847 717
SS-Rag1em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 8.02 mEq/d Download Values automated urine analysis - 66858 717
SS-Acad10em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 8.32 mEq/d 1.39 3.11 Download Values automated urine analysis - 66870 717
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 12.02 mEq/d 0.55 1.55 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51942 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 6 14.22 mEq/d 0.96 2.35 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52013 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 9.28 mEq/d 1.19 5.33 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52012 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 3 11.47 mEq/d 1.92 3.33 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52014 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 11 7.72 mEq/d 1.23 4.07 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52017 481
FHH-Chr 8BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 18.52 mEq/d 2.14 5.67 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52782 482
FHH-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 23.14 mEq/d 3.44 8.42 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52788 482
FHH-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 25.89 mEq/d 2.25 5.95 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52792 482
FHH-Chr 8BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 4 21.15 mEq/d 6.39 12.78 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52793 482
FHH-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 14.16 mEq/d 1.75 5.8 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52799 482
FHH-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 4 7.48 mEq/d 3.66 7.33 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52803 482
FHH-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 5 11.31 mEq/d 3.21 7.18 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52810 482
FHH-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 6 10.12 mEq/d 2.33 5.71 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52816 482
FHH-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 4 18.03 mEq/d 2.64 5.28 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52814 482
FHH-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 5 13.65 mEq/d 2.04 4.57 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52817 482
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 8 19.07 mEq/d 1.63 4.62 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52820 482
FHH-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 19.96 mEq/d 1.86 4.56 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52823 482
FHH-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 8 8.0 mEq/d 3.18 9.0 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52825 482
SS-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 12.59 mEq/d 2.85 9.44 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52731 482
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 18.68 mEq/d 2.46 7.78 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52735 482
SS-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 19.23 mEq/d 1.2 3.81 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52742 482
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 25.69 mEq/d 2.48 7.85 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52752 482
SS-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 19 13.54 mEq/d 1.29 5.61 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52756 482
SS-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 9.12 mEq/d 2.82 7.99 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52771 482
SS-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 12.32 mEq/d 1.69 5.33 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52773 482
SS-Chr 4BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 11.82 mEq/d 1.51 4.27 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52772 482
FHH-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 12.16 mEq/d 2.29 7.24 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52780 482
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 1.37 mEq/d 0.05 0.15 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51046 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.07 mEq/d 0.18 0.5 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51049 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.25 mEq/d 0.15 0.43 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51264 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 3 1.36 mEq/d 0.12 0.21 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51268 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 2.11 mEq/d 0.17 0.54 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51274 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 3 0.95 mEq/d 0.15 0.26 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51275 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 5 9.79 mEq/d 1.85 4.14 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51294 481
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 16 0.74 mEq/d 0.11 0.43 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51399 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 1.06 mEq/d 0.11 0.35 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51518 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.08 mEq/d 0.16 0.45 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51521 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.05 mEq/d 0.12 0.36 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51528 481
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 1.07 mEq/d 0.08 0.24 Download Values flame atomic emission spectrometry 50436 481
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 1.5 mEq/d 0.11 0.34 Download Values flame atomic emission spectrometry 50438 481
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 1.16 mEq/d 0.2 0.56 Download Values flame atomic emission spectrometry 50439 481
SS/HsdMcwiCrl urine sodium excretion rate controlled carbohydrate content diet (53 %) (for 63 days) and controlled fat content diet (14 %) (for 63 days) and controlled protein content diet (33 %) (for 63 days) then controlled carbohydrate content diet (69 %) (for 28 days) and controlled fat content diet (12 %) (for 28 days) and controlled protein content diet (19 %) (for 28 days) Spradley FT, et al., Am J Physiol Regul Integr Comp Physiol. 2012 Jan 1;302(1):R150-8. Epub 2011 Oct 26. urine sodium amount male 112.0 days 9 6.4 mEq/d 0.4 1.2 automated urine analysis 0.0 67668 735
SS-Sh2b3em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 10.46 mEq/d Download Values automated urine analysis - 43572 421
SS-Adra2aem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 8.73 mEq/d 1.0 2.0 Download Values automated urine analysis - 43581 421
SS-Nppbem2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 8.93 mEq/d 1.6 3.19 Download Values automated urine analysis - 44204 441
SS-Nppbem4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 9 12.05 mEq/d 0.75 2.26 Download Values automated urine analysis - 44206 441
SS-Stk39em2Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 9.46 mEq/d Download Values automated urine analysis - 44214 441
SS-Ulk3em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 11 11.76 mEq/d 1.19 3.94 Download Values automated urine analysis - 44217 441
SS-Mstnem3Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 7.44 mEq/d 2.73 4.73 Download Values automated urine analysis - 44215 441
SS-Cyp1a1em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 9.2 mEq/d 0.51 0.88 Download Values automated urine analysis - 44218 441
SS-Cyp1a1em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 8.43 mEq/d 1.06 1.83 Download Values automated urine analysis - 44219 441
SS-Prokr1em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 7.76 mEq/d 0.89 2.52 Download Values automated urine analysis - 44225 441
SS-Ulk3em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 10.87 mEq/d 2.31 4.0 Download Values automated urine analysis - 44233 441
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 12.43 mEq/d 0.47 1.25 Download Values automated urine analysis - 44240 441
SS-Tcf7l2em1Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 12.34 mEq/d 1.25 1.76 Download Values automated urine analysis - 44245 441
SS-Tcf7l2em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 9.71 mEq/d 0.94 2.98 Download Values automated urine analysis - 44250 441
SS-Cdh13em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 9.37 mEq/d 1.21 3.43 Download Values automated urine analysis - 44252 441
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 92.0 days-94.0 days 22 0.46 mEq/d 0.03 0.13 unspecified method 0.0 urine sodium analysis umol/min 69468 151
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77.0 days 14 1.4 mEq/d 0.13 0.5 automated urine sodium analysis 0.0 102469 2689
SD urine sodium excretion rate control condition Jung FF, etal., J Am Soc Nephrol. 1995 Feb;5(8):1573-80. urine sodium amount male 420.0 days-450.0 days 9 0.9 mEq/d 0.2 0.6 urine sodium analysis 0.0 101237 2582
MNS urine sodium excretion rate streptozotocin (50 mg/kg) (for 147 days) then insulin (2 IU/d) (for 147 days) Ge Y, et al., Physiol Rep. 2017 Feb;5(3). pii: 5/3/e13089. doi: 10.14814/phy2.13089. urine sodium amount male 213.0 days 9 2.07 mEq/d 0.45 1.36 urine sodium analysis 0.0 104032 2886
SS-Plod1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60.0 days-69.0 days 8.1 mEq/d 0.7 urine electrolyte analysis 0.0 98444 2059
WKY/NHsd urine sodium excretion rate standard rat chow (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 8 1.1 mEq/d 0.1 0.28 urine sodium analysis 0.0 99184 2238
SS-Renem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine sodium amount male 56.0 days 5 0.65 mEq/d 0.25 0.56 urine sodium analysis 0.0 98325 2038
SS-Renem1Mcwi+/- urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine sodium amount female 56.0 days 9 0.55 mEq/d 0.11 0.33 urine sodium analysis 0.0 98329 2038
SS-Renem1Mcwi-/- urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine sodium amount female 56.0 days 4 0.34 mEq/d 0.14 0.28 urine sodium analysis 0.0 98330 2038
MW urine sodium excretion rate nephrectomy (for 28 days) then enalapril (50 mg/l) (for 21 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. urine sodium amount male  days 7 1.5 mEq/d 0.15 0.4 flame photometry 0.0 5/6 nephrectomy 28 days 101049 2561
WKY urine sodium excretion rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 9 0.53 mEq/d 0.07 0.22 urine sodium analysis 0.0 100499 2479
WI urine sodium excretion rate controlled in utero environment (for 21 days) and standard diet (100 % of calories) (for 21 days) Ceravolo GS, et al., Life Sci. 2007 Jan 30;80(8):782-7. Epub 2006 Nov 10. urine sodium amount male 102.0 days 6 25.67 mEq/d 3.55 8.7 urine sodium analysis 0.0 101061 2563
SHRSP/A3NCrl urine sodium excretion rate control condition Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. urine sodium amount male 99.0 days-148.0 days 9 2.8 mEq/d 0.1 0.3 urine sodium analysis 86400.0 8 week 8 week control diet group 107064 3073
SHRSP/A3NCrl urine sodium excretion rate controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. urine sodium amount male 99.0 days-148.0 days 9 26.4 mEq/d 2.2 6.6 urine sodium analysis 86400.0 8 week HSFD 8 week high salt high fat diet group 107065 3073
SHRSP/A3NCrl urine sodium excretion rate controlled sodium chloride content drinking water (1 %) (for 56 days) and controlled fat content diet (24.5 %) (for 56 days) then controlled BAY60-4552 content diet (3 mg/kg/d) (for 49 days) Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. urine sodium amount male 99.0 days-148.0 days 9 16.0 mEq/d 2.0 6.0 urine sodium analysis 86400.0 8 week HSFD plus treatment 8 week high salt high fat plus treatment 107066 3073
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 6.06 mEq/d 1.29 2.88 Download Values automated urine analysis - 66813 717
SS-Gpr183em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 8.83 mEq/d 0.92 2.25 Download Values automated urine analysis - 66817 717
SS-Ulk4em3Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 8.48 mEq/d 1.31 2.63 Download Values automated urine analysis - 66818 717
SS-Tgfb1em3Mcwi+/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 11.14 mEq/d 1.82 3.16 Download Values automated urine analysis - 66823 717
SS-Apoeem8Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 7.57 mEq/d 1.3 2.9 Download Values automated urine analysis - 66828 717
SS-Gpr183em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 9 8.82 mEq/d 1.43 4.28 Download Values automated urine analysis - 66826 717
SS.BN-(D13Rat20-D13Got22)/Mcwi-Nckap5em4Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 12.12 mEq/d Download Values automated urine analysis - 66835 717
SS-Nckap5em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 9.34 mEq/d 0.12 0.17 Download Values automated urine analysis - 66846 717
SS-Apoeem8Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 6.36 mEq/d 5.17 7.31 Download Values automated urine analysis - 66848 717
SS-Renem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 7.2 mEq/d 0.99 1.98 Download Values automated urine analysis - 66855 717
SS-Bcas3em4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 11.56 mEq/d Download Values automated urine analysis - 66857 717
SS-Nckap5em3Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 11.79 mEq/d 0.69 1.2 Download Values automated urine analysis - 66864 717
SS-Mthfrem1Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 9.69 mEq/d 1.16 3.27 Download Values automated urine analysis - 66868 717
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 11.22 mEq/d 0.95 2.86 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51888 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 7.15 mEq/d 0.51 1.6 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51890 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 11.63 mEq/d 1.0 3.17 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51893 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 13.2 mEq/d 1.8 4.41 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51892 481
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 18.33 mEq/d 0.61 1.92 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52015 481
GH/OmrMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 12.03 mEq/d 0.87 2.47 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52018 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 13.71 mEq/d 0.45 1.42 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52016 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 10 13.82 mEq/d 1.3 4.11 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52020 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 3 12.33 mEq/d 1.71 2.97 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52021 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 16 14.02 mEq/d 1.77 7.07 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52783 482
FHH-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 21.52 mEq/d 1.69 5.36 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52798 482
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 48 18.43 mEq/d 0.86 5.95 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52801 482
FHH-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 17.44 mEq/d 3.27 8.66 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52802 482
FHH-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 14 11.64 mEq/d 1.13 4.21 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52812 482
FHH-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 21.2 mEq/d 2.45 6.01 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52819 482
LE/BluGill urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 16.09 mEq/d 2.02 6.07 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52827 482
FHH-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 11.87 mEq/d 2.05 6.48 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52826 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 12 15.1 mEq/d 1.32 4.57 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52732 482
SS-Chr 6BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 11.08 mEq/d 1.72 5.43 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52734 482
SS-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 13.1 mEq/d 1.27 3.35 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52737 482
SS-Chr 10BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 9.59 mEq/d 2.03 6.43 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52740 482
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 12.8 mEq/d 1.99 5.96 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52747 482
SS-Chr 5BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 20.67 mEq/d 1.77 5.6 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52746 482
SS-Chr 15BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 14.44 mEq/d 3.52 9.31 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52750 482
SS-Chr 3BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 17.73 mEq/d 1.8 4.76 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52754 482
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 64 14.23 mEq/d 0.97 7.78 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52761 482
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 8.38 mEq/d 0.48 1.51 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52764 482
SS-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 16.97 mEq/d 1.49 3.94 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52763 482
SS-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 24.35 mEq/d 2.98 8.95 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52770 482
SS-Chr 19BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 14.43 mEq/d 4.03 9.86 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52769 482
SS-Chr 12BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 19.17 mEq/d 2.94 8.3 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52775 482
WKY/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 12.18 mEq/d 0.61 1.82 Download Values flame atomic emission spectrometry 50869 481
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 1.39 mEq/d 0.12 0.29 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51045 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.32 mEq/d 0.09 0.28 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51273 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.23 mEq/d 0.15 0.45 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 51276 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 11.86 mEq/d 1.63 3.99 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51293 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 4 5.22 mEq/d 2.07 4.13 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51297 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 6 5.93 mEq/d 0.44 1.07 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51299 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 1.25 mEq/d 0.19 0.54 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51363 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 18 1.0 mEq/d 0.12 0.49 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51517 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 0.91 mEq/d 0.16 0.46 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51515 481
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 16 1.32 mEq/d 0.12 0.49 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51523 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 9 13.41 mEq/d 1.64 4.91 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51639 481
Crl:CD(SD) urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 10.47 mEq/d 1.07 3.21 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51641 481
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 7 1.07 mEq/d 0.15 0.39 Download Values flame atomic emission spectrometry 50437 481
SS-Rasgrp3em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 10.59 mEq/d 1.06 2.59 Download Values automated urine analysis - 43570 421
SS-Nppaem4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 12 7.91 mEq/d 1.1 3.81 Download Values automated urine analysis - 44196 441
SS-Agtrapem8Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 9.29 mEq/d 0.97 3.06 Download Values automated urine analysis - 44207 441
SS-Ulk3em1Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 6.61 mEq/d 3.13 5.43 Download Values automated urine analysis - 44211 441
SS-Plekha7em4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 11.67 mEq/d 1.11 1.57 Download Values automated urine analysis - 44221 441
SS-Plekha7em4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 12 9.46 mEq/d 0.82 2.84 Download Values automated urine analysis - 44223 441
SS-Agtr1aem5Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 10.36 mEq/d 1.37 1.94 Download Values automated urine analysis - 44227 441
SS-Aldh2em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 9.99 mEq/d 1.19 3.15 Download Values automated urine analysis - 44231 441
SS-Aldh2em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 10.58 mEq/d 0.46 1.14 Download Values automated urine analysis - 44235 441
SS-Plcd3em7Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 10.3 mEq/d 2.07 3.59 Download Values automated urine analysis - 44236 441
SS-Slc30a8em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 9 10.59 mEq/d 0.48 1.45 Download Values automated urine analysis - 44248 441
SS-Mstnem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 10.27 mEq/d 0.43 0.75 Download Values automated urine analysis - 44251 441
SS-Agtr1aem1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 10.23 mEq/d 0.63 1.99 Download Values automated urine analysis - 44249 441
SS-Msraem3Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 11.49 mEq/d 0.18 0.32 Download Values automated urine analysis - 44254 441
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 89.0 days-92.0 days 17 5.06 mEq/d 0.6 2.49 unspecified method 0.0 urine sodium analysis umol/min 69460 151
SS-Mthfrem1Mcwi-/+ urine sodium excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60.0 days-69.0 days 9.7 mEq/d 1.2 urine electrolyte analysis 0.0 98448 2059
SR/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 21 days) then 0.9% sodium chloride solution (for 21 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 77.0 days 19 2.2 mEq/d 0.16 0.7 automated urine sodium analysis 0.0 102468 2689
SS/NEisSlc urine sodium excretion rate controlled sodium chloride content diet (8 %) (for 7 days) Yoshihara F, et al., Regul Pept. 2005 May 15;128(1):7-13. urine sodium amount male 63.0 days 8 2.4 mEq/d 0.25 0.7 automated urine sodium analysis 0.0 102436 2689
SR/JrHsd urine sodium excretion rate gelled diet (200 g/kg/d) (for 8 days) then distilled water (for 6 days) Fenton RA, et al., Am J Physiol Renal Physiol. 2003 Jul;285(1):F143-51. Epub 2003 Apr 8. urine sodium amount male  days 6 0.62 mEq/d 0.05 0.12 automated urine sodium analysis 0.0 osmotic pump implant 6 days 102552 2691
SS-Nppbem2Mcwi-/- urine sodium excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60.0 days-69.0 days 7.4 mEq/d 1.1 urine electrolyte analysis 0.0 98445 2059
SS-Renem1Mcwi-/- urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Hypertension. 2011 Mar;57(3):614-9. doi: 10.1161/HYPERTENSIONAHA.110.163840. Epub 2011 Jan 17. urine sodium amount male 56.0 days 8 0.46 mEq/d 0.1 0.28 urine sodium analysis 0.0 98327 2038
MW urine sodium excretion rate sham surgical control condition (for 28 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. urine sodium amount male  days 7 1.28 mEq/d 0.07 0.19 flame photometry 0.0 sham surgery 28 days 101047 2561
WKY urine sodium excretion rate controlled enalapril content drinking water (50 mg/l) (for 22 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 5 0.04 mEq/d 0.01 0.03 urine sodium analysis 0.0 PA IV 50mg/kg 15 days 100501 2479
MNS urine sodium excretion rate control condition Capasso G, etal., Am J Physiol Renal Physiol. 2008 Aug;295(2):F556-67. doi: 10.1152/ajprenal.00340.2007. Epub 2008 May 14. urine sodium amount not specified 85.0 days-87.0 days 5 0.34 mEq/d 0.01 0.02 urine electrolyte analysis 0.0 110158 3164
MNS urine sodium excretion rate bendroflumethiazide (200 ug) (for 0.5 hours) Capasso G, etal., Am J Physiol Renal Physiol. 2008 Aug;295(2):F556-67. doi: 10.1152/ajprenal.00340.2007. Epub 2008 May 14. urine sodium amount not specified 85.0 days-87.0 days 5 2.89 mEq/d 0.7 1.57 urine electrolyte analysis 0.0 110159 3164
MHS urine sodium excretion rate bendroflumethiazide (200 ug) (for 0.5 hours) Capasso G, etal., Am J Physiol Renal Physiol. 2008 Aug;295(2):F556-67. doi: 10.1152/ajprenal.00340.2007. Epub 2008 May 14. urine sodium amount not specified 85.0 days-87.0 days 5 6.26 mEq/d 0.91 2.03 urine electrolyte analysis 0.0 110161 3164
SHRSP/A3NCrl urine sodium excretion rate control condition Costell MH, etal., Front Pharmacol. 2012 Jul 5;3:128. doi: 10.3389/fphar.2012.00128. eCollection 2012. urine sodium amount male 84.0 days-91.0 days 9 2.3 mEq/d 0.2 0.6 urine sodium analysis 86400.0 baseline baseline control group 107062 3073
SS-Acad10em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 13 9.57 mEq/d 1.12 4.05 Download Values automated urine analysis - 66820 717
SS-Nckap5em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 10.26 mEq/d 0.88 2.49 Download Values automated urine analysis - 66829 717
SS-Gpr183em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 9.2 mEq/d 0.15 0.22 Download Values automated urine analysis - 66830 717
SS-Gpr183em3Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 4 8.62 mEq/d 2.42 4.83 Download Values automated urine analysis - 66843 717
SS-Rag1em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 8 8.37 mEq/d 1.08 3.06 Download Values automated urine analysis - 66845 717
SS-Chr 5BN-Cyp4a2em1Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 12.96 mEq/d 1.9 3.29 Download Values automated urine analysis - 66852 717
SS-Mas1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 8.84 mEq/d 1.51 3.7 Download Values automated urine analysis - 66849 717
SS-Ets1em1Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 10.15 mEq/d 0.95 3.0 Download Values automated urine analysis - 66856 717
SS-Cybaem1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 8.17 mEq/d 4.75 6.71 Download Values automated urine analysis - 66860 717
FHH.BN-(D1Hmgc14-D1Hmgc15)/Mcwi-Rab38em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 9.45 mEq/d 5.89 8.32 Download Values automated urine analysis - 66861 717
SS-Tfdp2em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 10.53 mEq/d 0.84 1.45 Download Values automated urine analysis - 66859 717
SS-Nckap5em3Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 10.65 mEq/d 0.47 0.67 Download Values automated urine analysis - 66867 717
SS-Nox4em2Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 7.88 mEq/d 1.67 2.36 Download Values automated urine analysis - 66871 717
SS-Ncf2em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 10.7 mEq/d 0.99 2.21 Download Values automated urine analysis - 66831 717
FHH-Chr 1BN-Sorcs1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 12 6.21 mEq/d 0.8 2.78 Download Values automated urine analysis - 66832 717
SS-Cybaem1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 9.8 mEq/d 1.62 3.97 Download Values automated urine analysis - 66837 717
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 10.42 mEq/d 1.31 3.71 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51881 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 19 7.55 mEq/d 0.78 3.41 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51883 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 18 9.89 mEq/d 1.19 5.06 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51891 481
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 17 9.6 mEq/d 0.83 3.42 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51889 481
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 15 15.59 mEq/d 0.52 2.03 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51941 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 13.61 mEq/d 0.49 1.38 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52010 481
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 10.81 mEq/d 0.58 1.75 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Dyets 52022 481
FHH-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 9 8.89 mEq/d 1.85 5.54 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52800 482
FHH-Chr YBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 5 16.71 mEq/d 3.54 7.91 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52805 482
FHH-Chr 1BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 19.31 mEq/d 1.16 3.66 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52809 482
FHH-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 14.04 mEq/d 2.22 7.02 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52811 482
FHH-Chr 7BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 11 14.23 mEq/d 3.75 12.43 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52824 482
FHH-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 7 20.79 mEq/d 0.9 2.37 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52822 482
LE/BluGill urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 7 23.29 mEq/d 1.27 3.37 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52828 482
SS-Mmp2em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 9.82 mEq/d Download Values automated urine analysis - 66839 717
SS-Alms1em1Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 6.26 mEq/d Download Values automated urine analysis - 66851 717
SS-Nox4em2Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 9.51 mEq/d 0.72 1.61 Download Values automated urine analysis - 66853 717
SS-Chr 14BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 11.05 mEq/d 2.27 7.51 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52733 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 10 10.85 mEq/d 1.44 4.55 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52736 482
SS-Chr 17BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 15.57 mEq/d 1.84 5.52 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52741 482
SS-Chr 16BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 8 8.36 mEq/d 1.42 4.02 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52748 482
SS-Chr 13BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 16 11.92 mEq/d 1.33 5.31 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52757 482
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 15.96 mEq/d 2.07 6.2 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52755 482
SS-Chr 11BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 21 15.6 mEq/d 1.58 7.24 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52758 482
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 9 12.51 mEq/d 0.99 2.97 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52760 482
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount female 80.0 days-99.0 days 11 18.24 mEq/d 1.67 5.53 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52767 482
SS-Chr XBN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 6 14.01 mEq/d 3.51 8.61 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52778 482
SS-Chr 2BN/Mcwi urine sodium excretion rate controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data urine sodium amount male 80.0 days-99.0 days 10 18.08 mEq/d 2.1 6.64 Download Values flame atomic emission spectrometry Moms were fed Teklad, pups used in studies were fed Dyets 52779 482
LEW/Crl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 8 4.7 mEq/d 0.64 1.81 Download Values flame atomic emission spectrometry 50870 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 8 0.89 mEq/d 0.23 0.64 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51050 481
SS-Chr 18BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 4 0.79 mEq/d 0.09 0.17 Download Values flame atomic emission spectrometry Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 51048 481
F344/DuCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 10 1.24 mEq/d 0.13 0.4 Download Values flame atomic emission spectrometry 0 Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51365 481
Hsd:SD urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 20 1.19 mEq/d 0.1 0.46 Download Values flame atomic emission spectrometry Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51398 481
SS-Chr 9BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 16 1.23 mEq/d 0.16 0.63 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51520 481
FHH/EurMcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 5 0.8 mEq/d 0.21 0.46 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51526 481
SHR/NCrl urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount female 87.0 days-120.0 days 9 1.03 mEq/d 0.18 0.54 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51524 481
SS-Chr 20BN/Mcwi urine sodium excretion rate controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) and controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data urine sodium amount male 87.0 days-120.0 days 18 1.11 mEq/d 0.13 0.54 Download Values flame atomic emission spectrometry Moms and pups used in studies were fed Teklad 51525 481
SS-Rasgrp3em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 8.77 mEq/d 1.26 3.98 Download Values automated urine analysis - 43571 421
SS-Wdr72em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 10.72 mEq/d 0.75 1.99 Download Values automated urine analysis - 43573 421
SS-Sh2b3em1Mcwi-/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 9.4 mEq/d 1.19 2.05 Download Values automated urine analysis - 43574 421
SS-Agtrapem4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 3 10.12 mEq/d 1.35 2.33 Download Values automated urine analysis - 43579 421
SS-Agtrapem4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 6 10.07 mEq/d 0.86 2.12 Download Values automated urine analysis - 43580 421
SS-Hexim2em4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 10 8.89 mEq/d 1.16 3.67 Download Values automated urine analysis - 43582 421
SS-Cyp1a1em5Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 10.88 mEq/d 0.47 0.66 Download Values automated urine analysis - 44203 441
SS-Msraem4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 8.58 mEq/d 0.79 1.76 Download Values automated urine analysis - 44205 441
SS-Plekha7em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 9 10.6 mEq/d 1.21 3.63 Download Values automated urine analysis - 44226 441
SS-Nppbem4Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 9 7.39 mEq/d 1.1 3.3 Download Values automated urine analysis - 44228 441
SS-Prokr1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 5 7.2 mEq/d 2.14 4.78 Download Values automated urine analysis - 44229 441
SS-Cyp1a1em1Mcwi-/- urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 7 8.71 mEq/d 0.85 2.25 Download Values automated urine analysis - 44239 441
SS-Agtrapem8Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 10.23 mEq/d 1.41 1.99 Download Values automated urine analysis - 44243 441
SS-Slc30a8em2Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 1 9.6 mEq/d Download Values automated urine analysis - 44244 441
SS-Nppaem4Mcwi+/+ urine sodium excretion rate controlled sodium content diet (4 %) (for 14 days) PhysGen Knockout data urine sodium amount male 70.0 days-77.0 days 2 9.78 mEq/d 0.49 0.69 Download Values automated urine analysis - 44255 441
SS.SHR-(D2Rat61-D2Mco18)/Mco urine sodium excretion rate control condition (for 140 days) Garrett MR, et al., Physiol Genomics. 2007 May 15;. urine sodium amount male 140.0 days 6 0.45 mEq/d 0.02 0.05 urine sodium analysis 0.0 urine sodium analysis 68012 834
SHR/NHsdMco urine sodium excretion rate control condition (for 140 days) Garrett MR, et al., Physiol Genomics. 2007 May 15;. urine sodium amount male 140.0 days 6 0.82 mEq/d 0.05 0.12 urine sodium analysis 0.0 urine sodium analysis 68011 834
SS/JrTol urine sodium excretion rate control condition (for 140 days) Garrett MR, et al., Physiol Genomics. 2007 May 15;. urine sodium amount male 140.0 days 6 0.43 mEq/d 0.03 0.07 urine sodium analysis 0.0 urine sodium analysis 68013 834
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 89.0 days-92.0 days 24 6.35 mEq/d 0.35 1.74 unspecified method 0.0 urine sodium analysis umol/min 69459 151
SS-Clcn6em2Mcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (between 56 and 63 days) then controlled sodium content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60.0 days-69.0 days 5.6 mEq/d 0.9 urine electrolyte analysis 0.0 98447 2059
SS-Nppaem4Mcwi-/- urine sodium excretion rate controlled sodium chloride content diet (0.4 %) (between 56 and 63 days) then controlled sodium chloride content diet (4 %) (for 12 days) Flister MJ, et al., Genome Res. 2013 Dec;23(12):1996-2002. doi: 10.1101/gr.160283.113. Epub 2013 Sep 4. urine sodium amount male 60.0 days-69.0 days 8.6 mEq/d 1.0 urine electrolyte analysis 0.0 98446 2059
WKY/NHsd urine sodium excretion rate controlled sodium content diet (8 %) (for 8 days) then 0.9% sodium chloride solution (0.9 %) (for 8 days) then sunitinib (7 mg/kg/d) (for 8 days) Lankhorst S, et al., Hypertension. 2017 May;69(5):919-926. doi: 10.1161/HYPERTENSIONAHA.116.08565. Epub 2017 Mar 20. urine sodium amount male  days 8 34.3 mEq/d 1.8 5.09 urine sodium analysis 0.0 99186 2238
WKY urine sodium excretion rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 7 0.03 mEq/d 0.01 0.02 urine sodium analysis 0.0 PA IV 50mg/kg 15 days 100500 2479
WKY urine sodium excretion rate 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 8 0.63 mEq/d 0.03 0.08 urine sodium analysis 0.0 100502 2479
WKY urine sodium excretion rate puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 8 0.73 mEq/d 0.2 0.57 urine sodium analysis 0.0 PA IV 50mg/kg 490 days 100506 2479
WKY urine sodium excretion rate controlled enalapril content drinking water (50 mg/l) (for 7 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 8 0.3 mEq/d 0.04 0.12 urine sodium analysis 0.0 PA IV 50mg/kg 100504 2479
WKY urine sodium excretion rate controlled enalapril content drinking water (50 mg/kg) (for 497 days) then puromycin aminonucleoside (50 mg/l) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. urine sodium amount male  days 9 0.69 mEq/d 0.24 0.73 urine sodium analysis 0.0 PA IV 50mg/kg 490 days 100507 2479
WI urine sodium excretion rate controlled in utero environment (for 21 days) and standard diet (50 % of calories) (for 21 days) Ceravolo GS, et al., Life Sci. 2007 Jan 30;80(8):782-7. Epub 2006 Nov 10. urine sodium amount male 102.0 days 6 35.17 mEq/d 6.7 16.41 urine sodium analysis 0.0 101062 2563
MHS urine sodium excretion rate control condition Capasso G, etal., Am J Physiol Renal Physiol. 2008 Aug;295(2):F556-67. doi: 10.1152/ajprenal.00340.2007. Epub 2008 May 14. urine sodium amount not specified 85.0 days-87.0 days 5 0.54 mEq/d 0.12 0.26 urine electrolyte analysis 0.0 110160 3164