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Strain
Phenotype
Conditions
Study
Experiment Name
Sex
Age
# of Animals
Value
Units
SEM
SD
Individual Records
Method
Method Duration
Post Insult Time Value
Experiment Notes
Record ID
Study ID
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
female
70.0 days-84.0 days
8
66.13
%
6.37
18.0
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
55389
522
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
male
70.0 days-84.0 days
15
62.53
%
4.49
17.39
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
56747
522
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
salidroside (40 mg/kg) (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
90.64
%
2.0
5.29
wire myography
0.0
103591
2827
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
female
70.0 days-84.0 days
18
70.67
%
3.59
15.22
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
56754
522
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
control condition
Steireif C, etal., J Hypertens. 2013 Nov;31(11):2203-12; discussion 2212. doi: 10.1097/HJH.0b013e3283642384.
vasodilation trait
male
84.0 days
10
81.1
%
3.0
9.49
wire myography
0.0
109367
3141
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours)
PhysGen Vascular data
vasodilation trait
male
70.0 days-84.0 days
12
54.25
%
6.09
21.08
Download Values
wire myography using a Digi-Med tissue force analysis system with force transducer
Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan
55382
522
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
vehicle control condition (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
89.88
%
2.56
6.77
wire myography
0.0
103590
2827
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
vehicle control condition (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
99.75
%
2.32
6.14
wire myography
0.0
103606
2827
WKY/NCrl
acetylcholine-induced blood vessel dilation expressed as percent reduction of the force generated in a pre-constricted blood vessel
salidroside (40 mg/kg) (for 28 days)
Alameddine A, et al., J Physiol Pharmacol. 2015 Apr;66(2):249-57.
vasodilation trait
male
168.0 days
7
96.2
%
1.31
3.47
wire myography
0.0
103607
2827