| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
10 |
2.16 |
E-7mole |
1.14 |
3.59 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
|
63216 |
528 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
81 |
1.53 |
E-7mole |
0.12 |
1.11 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
55934 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
13 |
1.27 |
E-7mole |
0.38 |
1.36 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
54596 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
12 |
3.72 |
E-7mole |
0.53 |
1.84 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
55975 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
10 |
1.49 |
E-7mole |
0.22 |
0.69 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
55942 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
15 |
1.66 |
E-7mole |
0.39 |
1.51 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
54588 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
15 |
1.03 |
E-7mole |
0.21 |
0.81 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
56793 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
12 |
2.84 |
E-7mole |
0.48 |
1.66 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
57126 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
5 |
0.63 |
E-7mole |
0.18 |
0.41 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
|
63222 |
528 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
7 |
2.42 |
E-7mole |
0.39 |
1.04 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
55977 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
8 |
1.65 |
E-7mole |
0.22 |
0.62 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
57131 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
79 |
1.63 |
E-7mole |
0.17 |
1.52 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
56560 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
female |
70.0 days-84.0 days |
13 |
1.46 |
E-7mole |
0.26 |
0.95 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
56566 |
522 |
| SS/JrHsdMcwi |
concentration of acetylcholine at which the reduction in force during dilation of a blood vessel is half the maximum value (EC50) |
phenylephrine (1 umol/l) (for 0.2 hours) then acetylcholine (0-30 umol/l) and drug dose time series (for 1 hours) |
PhysGen Vascular data |
vasodilation trait |
male |
70.0 days-84.0 days |
12 |
1.53 |
E-7mole |
0.34 |
1.16 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
56785 |
522 |