| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
5 |
0.02 |
umol/l |
0.0 |
0.01 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
|
62976 |
528 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
12 |
0.05 |
umol/l |
0.01 |
0.03 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
57302 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
10 |
0.01 |
umol/l |
0.0 |
0.01 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
54722 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
90 |
0.06 |
umol/l |
0.01 |
0.06 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
54946 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
15 |
0.08 |
umol/l |
0.02 |
0.06 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
54952 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
12 |
0.63 |
umol/l |
0.28 |
0.96 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
54994 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
10 |
0.08 |
umol/l |
0.02 |
0.05 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
57304 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
9 |
0.06 |
umol/l |
0.01 |
0.02 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
55128 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
85 |
0.06 |
umol/l |
0.01 |
0.13 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Teklad |
54714 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
11 |
0.21 |
umol/l |
0.14 |
0.46 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
56875 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
13 |
0.38 |
umol/l |
0.14 |
0.5 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
54986 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
12 |
0.07 |
umol/l |
0.01 |
0.03 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks |
55123 |
522 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (1 %) (for 14 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
male |
70.0 days-84.0 days |
11 |
0.02 |
umol/l |
0.0 |
0.01 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
|
62970 |
528 |
| SS/JrHsdMcwi |
concentration of phenylephrine at which the force of blood vessel contraction is half the maximum value (EC50) |
controlled sodium content diet (4 %) (for 21 days) then phenylephrine (0-300 umol/l) and drug dose time series (for 1.2 hours) |
PhysGen Vascular data |
vasoconstriction trait |
female |
70.0 days-84.0 days |
15 |
0.19 |
umol/l |
0.07 |
0.28 |
Download Values
|
wire myography using a Digi-Med tissue force analysis system with force transducer |
|
|
Moms and pups used in studies were fed Dyets |
56883 |
522 |