| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 6 |
7.22 |
g/kg |
0.34 |
0.83 |
post excision weight measurement |
0.0 |
|
103422 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 7 |
8.05 |
g/kg |
0.24 |
0.63 |
post excision weight measurement |
0.0 |
|
102697 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 11 |
6.24 |
g/kg |
0.07 |
0.23 |
post excision weight measurement |
0.0 |
|
102764 |
2721 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 7 |
6.81 |
g/kg |
0.19 |
0.5 |
post excision weight measurement |
0.0 |
|
103419 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
6.22 |
g/kg |
0.21 |
0.59 |
post excision weight measurement |
0.0 |
|
103420 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
5.87 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
0.0 |
|
103421 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 7 |
7.3 |
g/kg |
0.09 |
0.24 |
post excision weight measurement |
0.0 |
|
103423 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 9 |
7.02 |
g/kg |
0.18 |
0.54 |
post excision weight measurement |
0.0 |
|
102695 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 14 |
6.65 |
g/kg |
0.08 |
0.3 |
post excision weight measurement |
0.0 |
|
102765 |
2721 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 8 |
6.95 |
g/kg |
0.23 |
0.65 |
post excision weight measurement |
0.0 |
|
102694 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 11 |
6.44 |
g/kg |
0.14 |
0.46 |
post excision weight measurement |
0.0 |
|
102696 |
2703 |