| SS/Jr |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
kidney mass |
male |
114.0 days-118.0 days |
4 |
|
11.87 |
g/kg |
0.92 |
1.84 |
post excision weight measurement |
|
0 |
|
|
|
65100 |
283 |
| SS.LEW-(D18Chm41-D18Rat92)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
10.1 |
g/kg |
0.4 |
0.89 |
post excision weight measurement |
|
0 |
|
|
|
64775 |
226 |
| SS.LEW-(D17Chm14-D17Rat181)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
9.7 |
g/kg |
0.2 |
0.45 |
post excision weight measurement |
|
0 |
|
|
|
64779 |
226 |
| SS.LEW-(D3Rat61-D3Wox1)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 7 |
|
10.1 |
g/kg |
0.4 |
1.06 |
post excision weight measurement |
|
0 |
|
|
|
64790 |
226 |
| SS.LEW-(D3Rat52-D3Rat130)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 7 |
|
9.5 |
g/kg |
0.2 |
0.53 |
post excision weight measurement |
|
0 |
|
|
|
64793 |
226 |
| SS.MNS-(D2Chm51-D2Rat341)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 8 |
|
9.9 |
g/kg |
0.2 |
0.57 |
post excision weight measurement |
|
0 |
|
|
|
64795 |
226 |
| SS.MNS-(D2Wox27-Adh1)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
10.3 |
g/kg |
0.2 |
0.45 |
post excision weight measurement |
|
0 |
|
|
|
64796 |
226 |
| SS.LEW-(D2Rat199-D2Mco17)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 8 |
|
11.4 |
g/kg |
0.6 |
1.7 |
post excision weight measurement |
|
0 |
|
|
|
64799 |
226 |
| SHR/OlaIpcv |
both kidneys wet weight to body weight ratio |
control condition (for 20 days) |
Pravenec M, et al., Physiol Res 2003;52(3):285-9. |
kidney mass |
male |
80.0 days-100.0 days |
10 |
|
8.07 |
g/kg |
0.36 |
1.14 |
post excision weight measurement |
|
0 |
|
|
|
65507 |
612 |
| SS.SR-(D3Arb14-D3Mco36)(D7Mco19-D7Mco7)/Mco |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
kidney mass |
male |
114.0 days-118.0 days |
6 |
|
10.45 |
g/kg |
0.21 |
0.51 |
post excision weight measurement |
|
0 |
|
|
|
65128 |
283 |
| SHR/FubRkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. |
kidney mass |
female |
168.0 days
| 10 |
|
6.15 |
g/kg |
0.16 |
0.51 |
post excision weight measurement |
|
0.0 |
|
|
|
68169 |
309 |
| WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both kidneys wet weight to body weight ratio |
control condition |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
kidney mass |
not specified |
112.0 days
| 10 |
|
7.69 |
g/kg |
0.11 |
0.35 |
post excision weight measurement |
|
0.0 |
|
|
|
68699 |
971 |
| PXO8-1/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 10 |
|
5.6 |
g/kg |
0.04 |
0.13 |
post excision weight measurement |
|
0.0 |
|
|
|
97123 |
1858 |
| PXO7-1/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 8 |
|
5.8 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
|
0.0 |
|
|
|
97127 |
1858 |
| PXO1/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 11 |
|
5.9 |
g/kg |
0.1 |
0.33 |
post excision weight measurement |
|
0.0 |
|
|
|
97149 |
1858 |
| PXO3-2/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 9 |
|
6.0 |
g/kg |
0.1 |
0.3 |
post excision weight measurement |
|
0.0 |
|
|
|
97152 |
1858 |
| PXO6-1/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 10 |
|
6.0 |
g/kg |
0.1 |
0.32 |
post excision weight measurement |
|
0.0 |
|
|
|
97151 |
1858 |
| PXO5-2/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 10 |
|
6.0 |
g/kg |
0.1 |
0.32 |
post excision weight measurement |
|
0.0 |
|
|
|
97156 |
1858 |
| SHRSP.WKY-(D3Mgh16-D3Rat114)/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| |
|
3.65 |
g/kg |
0.2 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102120 |
2646 |
| SHRSP.WKY-(D3Mgh16-rs65433898)/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| |
|
4.16 |
g/kg |
0.4 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102123 |
2646 |
| SR/NEisSlc |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) |
Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. |
kidney mass |
male |
126.0 days
| 8 |
|
3.53 |
g/kg |
0.04 |
0.11 |
post excision weight measurement |
|
0.0 |
|
|
|
102322 |
2684 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 11 |
|
6.24 |
g/kg |
0.07 |
0.23 |
post excision weight measurement |
|
0.0 |
|
|
|
102764 |
2721 |
| LH/MavRrrc |
both kidneys wet weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 8 |
|
6.36 |
g/kg |
0.08 |
0.23 |
post excision weight measurement |
|
0.0 |
|
|
|
102693 |
2703 |
| LL/Mav |
both kidneys wet weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 13 |
|
6.53 |
g/kg |
0.04 |
0.14 |
post excision weight measurement |
|
0.0 |
|
|
|
102692 |
2703 |
| SR/JrIpcv |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) |
Hojn¿ S, et al., Physiol Res. 2005;54(2):201-6. |
kidney mass |
male |
days
| |
|
7.24 |
g/kg |
0.1 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102393 |
2688 |
| SHRSP.WKY-(D3Mgh16-D3Mit10)/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| |
|
4.2 |
g/kg |
0.62 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102125 |
2646 |
| SHR/N-cp |
both kidneys wet weight to body weight ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney mass |
male |
140.0 days-168.0 days |
8 |
|
1.83 |
g/kg |
0.31 |
0.88 |
post excision weight measurement |
|
0.0 |
|
|
|
101525 |
2601 |
| SS-Kcnj1em1Kasu-/- |
both kidneys wet weight to body weight ratio |
control condition (for 13 days) |
Zhou X, et al., Hypertension. 2013 Aug;62(2):288-94. doi: 10.1161/HYPERTENSIONAHA.111.01051. Epub 2013 Jun 10. |
kidney mass |
male |
13.0 days
| 5 |
|
13.4 |
g/kg |
0.6 |
1.34 |
post excision weight measurement |
|
0.0 |
|
|
|
104423 |
2948 |
| SBN/Ygl |
both kidneys wet weight to body weight ratio |
deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and darusentan (50 mg/kg/d) (for 56 days) |
Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. |
kidney mass |
male |
16.0 days
| 8 |
|
2.7 |
g/kg |
0.08 |
0.23 |
post excision weight measurement |
|
0.0 |
|
n=8-15 |
|
106648 |
3035 |
| WKY/NMolTac |
both kidneys wet weight to body weight ratio |
control condition |
Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. |
kidney mass |
female |
420.0 days
| |
|
2.93 |
g/kg |
0.08 |
|
post excision weight measurement |
|
0.0 |
|
|
kidney weight, kidney weight to body weight ratio |
106954 |
3071 |
| Hsd:WI |
both kidneys wet weight to body weight ratio |
control condition |
Rothermund L, etal., J Hypertens. 2006 Sep 24(9). |
kidney mass |
male |
100.0 days
| 16 |
|
5.7 |
g/kg |
0.2 |
0.8 |
post excision weight measurement |
|
0.0 |
|
|
|
108101 |
3115 |
| SS/Jr |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 16 |
|
12.1 |
g/kg |
0.3 |
1.2 |
post excision weight measurement |
|
0 |
|
|
|
64772 |
226 |
| SS.LEW-(D16Rat38-D16Chm66)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 8 |
|
10.5 |
g/kg |
0.4 |
1.13 |
post excision weight measurement |
|
0 |
|
|
|
64782 |
226 |
| SS.LEW-(D8Rat56-D8Rat51)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 9 |
|
11.1 |
g/kg |
0.4 |
1.2 |
post excision weight measurement |
|
0 |
|
|
|
64788 |
226 |
| MWF/FubRkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 |
kidney mass |
not specified |
168.0 days
| 18 |
|
5.44 |
g/kg |
0.06 |
0.25 |
post excision weight measurement |
|
0.0 |
|
|
|
65366 |
117 |
| ISIAH |
both kidneys wet weight to body weight ratio |
control condition |
Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. |
kidney mass |
not specified |
180.0 days
| 11 |
|
7.0 |
g/kg |
0.1 |
0.33 |
post excision weight measurement |
|
0.0 |
|
|
|
68058 |
835 |
| SHR.BN-(D8Mit5-D8Mgh6)/Ipcv |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 13 |
|
6.2 |
g/kg |
0.1 |
0.36 |
post excision weight measurement |
|
0.0 |
|
|
|
97121 |
1858 |
| PXO4/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 9 |
|
6.3 |
g/kg |
0.1 |
0.3 |
post excision weight measurement |
|
0.0 |
|
|
|
97153 |
1858 |
| PXO3-1/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 10 |
|
6.3 |
g/kg |
0.1 |
0.32 |
post excision weight measurement |
|
0.0 |
|
|
|
97154 |
1858 |
| PXO6-3/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 10 |
|
5.9 |
g/kg |
0.1 |
0.32 |
post excision weight measurement |
|
0.0 |
|
|
|
97148 |
1858 |
| SHR/OlaIpcv |
both kidneys wet weight to body weight ratio |
control condition (for 20 days) |
Pravenec M, et al., Physiol Res 2003;52(3):285-9. |
kidney mass |
male |
28.0 days
| 5 |
|
4.73 |
g/kg |
0.1 |
0.22 |
post excision weight measurement |
|
0.0 |
|
|
|
97080 |
612 |
| FHH/EurMcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
168.0 days
| 6 |
|
8.1 |
g/kg |
0.18 |
0.44 |
post excision weight measurement |
|
0.0 |
|
|
|
99461 |
2318 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 14 |
|
6.65 |
g/kg |
0.08 |
0.3 |
post excision weight measurement |
|
0.0 |
|
|
|
102765 |
2721 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) and reserpine (0.75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 7 |
|
7.3 |
g/kg |
0.09 |
0.24 |
post excision weight measurement |
|
0.0 |
|
|
|
103423 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (0.01 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 9 |
|
7.02 |
g/kg |
0.18 |
0.54 |
post excision weight measurement |
|
0.0 |
|
|
|
102695 |
2703 |
| SHR/N-cp |
both kidneys wet weight to body weight ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney mass |
male |
168.0 days-196.0 days |
8 |
|
1.67 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
|
0.0 |
|
|
|
101524 |
2601 |
| Crl:SD |
both kidneys wet weight to body weight ratio |
control condition (for 63 days) |
Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011. |
kidney mass |
male |
63.0 days
| 5 |
|
0.1 |
g/kg |
0.0 |
0.0 |
post excision weight measurement |
|
0.0 |
|
|
|
105047 |
3010 |
| SD-Abcb11em1Sage |
both kidneys wet weight to body weight ratio |
control condition (for 63 days) |
Cheng Y, et al., Biopharm Drug Dispos. 2016 Jul;37(5):276-86. doi: 10.1002/bdd.2011. |
kidney mass |
male |
63.0 days
| 5 |
|
0.09 |
g/kg |
0.0 |
0.01 |
post excision weight measurement |
|
0.0 |
|
|
|
105048 |
3010 |
| SBN/Ygl |
both kidneys wet weight to body weight ratio |
deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) |
Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. |
kidney mass |
male |
16.0 days
| 8 |
|
2.6 |
g/kg |
0.05 |
0.14 |
post excision weight measurement |
|
0.0 |
|
n=8-15 |
|
106647 |
3035 |
| SHRSP/A3N |
both kidneys wet weight to body weight ratio |
controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and eprosartan (60 mg/kg/d) (between 42 and 77 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
kidney mass |
male |
126.0 days-182.0 days |
|
|
8.8 |
g/kg |
0.4 |
|
post excision weight measurement |
kidney |
0.0 |
|
|
|
107536 |
3090 |
| LEW |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 6 |
|
7.91 |
g/kg |
0.09 |
0.22 |
post excision weight measurement |
|
0 |
|
|
|
64771 |
226 |
| SS.LEW-(D18Chm91-D18Rat67)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
10.0 |
g/kg |
0.4 |
0.89 |
post excision weight measurement |
|
0 |
|
|
|
64774 |
226 |
| SS.LEW-(D17Rat65-D17Chm2)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
10.2 |
g/kg |
0.4 |
0.89 |
post excision weight measurement |
|
0 |
|
|
|
64778 |
226 |
| SS.LEW-(D3Mco21-D3Rat17)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 4 |
|
9.5 |
g/kg |
0.3 |
0.6 |
post excision weight measurement |
|
0 |
|
|
|
64792 |
226 |
| SS.MNS-(D2Chm25-Fgg)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 9 |
|
10.6 |
g/kg |
0.2 |
0.6 |
post excision weight measurement |
|
0 |
|
|
|
64794 |
226 |
| SS.LEW-(D3Got33-D3Chm68)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 10 |
|
10.4 |
g/kg |
0.2 |
0.63 |
post excision weight measurement |
|
0 |
|
|
|
64791 |
226 |
| SS.MNS-(D2Chm25-D2Rat131)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
9.8 |
g/kg |
0.3 |
0.67 |
post excision weight measurement |
|
0 |
|
|
|
64797 |
226 |
| LEW/Rkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. |
kidney mass |
not specified |
126.0 days
| 8 |
|
5.93 |
g/kg |
0.53 |
1.5 |
post excision weight measurement |
|
0.0 |
|
|
|
67598 |
769 |
| SS.SR-(D7Mco19-D7Mco7)/Jr |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
kidney mass |
male |
114.0 days-118.0 days |
3 |
|
10.53 |
g/kg |
0.18 |
0.31 |
post excision weight measurement |
|
0 |
|
|
|
65127 |
283 |
| COP.DA-(D16Rat12-D16Rat90)/Mco |
both kidneys wet weight to body weight ratio |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
kidney mass |
not specified |
105.0 days
| 8 |
|
6.49 |
g/kg |
0.18 |
0.51 |
post excision weight measurement |
|
0.0 |
|
|
|
68523 |
933 |
| WKY.SHRSP-(D1Wox29-D1Arb21)/Izm |
both kidneys wet weight to body weight ratio |
cold ambient air exposure (4 degrees C) (for 90 days) |
Cui ZH, et al., J Hypertens 2004 Nov;22(11):2103-9. |
kidney mass |
not specified |
112.0 days
| 10 |
|
8.17 |
g/kg |
0.11 |
0.34 |
post excision weight measurement |
|
0.0 |
|
|
|
68701 |
971 |
| PXO9/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 9 |
|
6.0 |
g/kg |
0.1 |
0.3 |
post excision weight measurement |
|
0.0 |
|
|
|
97150 |
1858 |
| PXO8-2/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 13 |
|
5.5 |
g/kg |
0.1 |
0.36 |
post excision weight measurement |
|
0.0 |
|
|
|
97122 |
1858 |
| SHR.BN-(D5Wox12-D5Wox20)/Ipcv |
both kidneys wet weight to body weight ratio |
control condition |
Pravenec M, et al., Physiol Res 2003;52(3):285-9. |
kidney mass |
male |
80.0 days-100.0 days |
5 |
|
4.71 |
g/kg |
0.1 |
0.22 |
post excision weight measurement |
|
0.0 |
|
|
|
97081 |
612 |
| SHRSP.WKY-(D3Wox20-D3Rat114)/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| 6 |
|
3.78 |
g/kg |
0.18 |
0.44 |
post excision weight measurement |
|
0.0 |
|
|
|
102121 |
2646 |
| SS/NEisSlc |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then vehicle control condition (for 49 days) |
Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. |
kidney mass |
male |
126.0 days
| 8 |
|
5.19 |
g/kg |
0.19 |
0.54 |
post excision weight measurement |
|
0.0 |
|
|
|
102323 |
2684 |
| SS/NEisSlc |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (for 42 days) then controlled sodium content diet (8 %) (for 77 days) then tolvaptan (0.05 %) (for 49 days) |
Ishikawa M, et al., Int Heart J. 2013;54(2):98-106. |
kidney mass |
male |
126.0 days
| 8 |
|
4.55 |
g/kg |
0.06 |
0.17 |
post excision weight measurement |
|
0.0 |
|
|
|
102324 |
2684 |
| FHH-Nr4a1m1Mcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
112.0 days
| 6 |
|
10.3 |
g/kg |
0.14 |
0.34 |
post excision weight measurement |
|
0.0 |
|
|
|
99460 |
2318 |
| FHH/EurMcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
112.0 days
| 6 |
|
9.2 |
g/kg |
0.27 |
0.66 |
post excision weight measurement |
|
0.0 |
|
|
|
99459 |
2318 |
| LL/Mav |
both kidneys wet weight to body weight ratio |
vehicle control condition |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 9 |
|
6.08 |
g/kg |
0.07 |
0.21 |
post excision weight measurement |
|
0.0 |
|
|
|
102762 |
2721 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (0.4 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
|
6.22 |
g/kg |
0.21 |
0.59 |
post excision weight measurement |
|
0.0 |
|
|
|
103420 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
perindopril (1.5 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 8 |
|
5.87 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
|
0.0 |
|
|
|
103421 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 8 |
|
6.95 |
g/kg |
0.23 |
0.65 |
post excision weight measurement |
|
0.0 |
|
|
|
102694 |
2703 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then perindopril (1 mg/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 11 |
|
6.44 |
g/kg |
0.14 |
0.46 |
post excision weight measurement |
|
0.0 |
|
|
|
102696 |
2703 |
| SS/JrIpcv |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) |
Hojn¿ S, et al., Physiol Res. 2005;54(2):201-6. |
kidney mass |
male |
days
| |
|
6.39 |
g/kg |
0.12 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102394 |
2688 |
| SHR/N-cp |
both kidneys wet weight to body weight ratio |
standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) |
Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. |
kidney mass |
male |
168.0 days-196.0 days |
8 |
|
1.88 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
|
0.0 |
|
|
|
101523 |
2601 |
| SBH/Ygl |
both kidneys wet weight to body weight ratio |
sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) |
Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. |
kidney mass |
male |
16.0 days
| 8 |
|
2.6 |
g/kg |
0.07 |
0.2 |
post excision weight measurement |
|
0.0 |
|
n=8-15 |
|
106649 |
3035 |
| SHRSP/A3N |
both kidneys wet weight to body weight ratio |
control condition (between 42 and 77 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
kidney mass |
male |
126.0 days-182.0 days |
|
|
7.1 |
g/kg |
0.2 |
|
post excision weight measurement |
kidney |
0.0 |
|
|
|
107534 |
3090 |
| SHRSP/A3N |
both kidneys wet weight to body weight ratio |
controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
kidney mass |
male |
126.0 days-182.0 days |
|
|
13.0 |
g/kg |
0.7 |
|
post excision weight measurement |
kidney |
0.0 |
|
|
|
107535 |
3090 |
| MWF/FubRkb |
both kidneys wet weight to body weight ratio |
control condition |
Rothermund L, etal., J Hypertens. 2006 Sep 24(9). |
kidney mass |
male |
100.0 days
| 10 |
|
6.2 |
g/kg |
0.1 |
0.32 |
post excision weight measurement |
|
0.0 |
|
|
|
108102 |
3115 |
| SS.LEW-(D18Chm56-D18Rat55)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
11.5 |
g/kg |
0.6 |
1.34 |
post excision weight measurement |
|
0 |
|
|
|
64773 |
226 |
| SS.LEW-(D16Got3-D16Rat112)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 9 |
|
10.1 |
g/kg |
0.2 |
0.6 |
post excision weight measurement |
|
0 |
|
|
|
64780 |
226 |
| SS.LEW-(D10Chm128-D10Chm121)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 9 |
|
10.5 |
g/kg |
0.5 |
1.5 |
post excision weight measurement |
|
0 |
|
|
|
64785 |
226 |
| SS.LEW-(D10Chm128-D10Chm169)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 8 |
|
10.0 |
g/kg |
0.3 |
0.85 |
post excision weight measurement |
|
0 |
|
|
|
64783 |
226 |
| SS.LEW-(D10Rat24-Igfbp4)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 5 |
|
10.0 |
g/kg |
0.4 |
0.89 |
post excision weight measurement |
|
0 |
|
|
|
64786 |
226 |
| SS.LEW-(D10Chm10-D10Rat11)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 7 |
|
10.1 |
g/kg |
0.2 |
0.53 |
post excision weight measurement |
|
0 |
|
|
|
64784 |
226 |
| SS.LEW-(D16Rat12-D16Chm23)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 10 |
|
11.4 |
g/kg |
0.2 |
0.63 |
post excision weight measurement |
|
0 |
|
|
|
64781 |
226 |
| SS.MNS-(D2Rat183-D2Chm113)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 8 |
|
9.9 |
g/kg |
0.2 |
0.57 |
post excision weight measurement |
|
0 |
|
|
|
64798 |
226 |
| SS.LEW-(D2Rat18-D2Chm277)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 6 |
|
12.2 |
g/kg |
0.3 |
0.73 |
post excision weight measurement |
|
0 |
|
|
|
64800 |
226 |
| SS.LEW-(D18Rat30-D18Chm29)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 8 |
|
10.4 |
g/kg |
0.2 |
0.57 |
post excision weight measurement |
|
0 |
|
|
|
64801 |
226 |
| SHR/FubRkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 |
kidney mass |
not specified |
168.0 days
| 10 |
|
5.9 |
g/kg |
0.05 |
0.16 |
post excision weight measurement |
|
0.0 |
|
|
|
65364 |
117 |
| MWF-Chr 6SHR/Rkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol. 2007 Jan;18(1):113-21 |
kidney mass |
not specified |
168.0 days
| 19 |
|
5.62 |
g/kg |
0.18 |
0.78 |
post excision weight measurement |
|
0.0 |
|
|
|
65365 |
117 |
| LEW/Cub |
both kidneys wet weight to body weight ratio |
losartan (10 mg/kg) (for 0.2 hours) then pentolinium (5 mg/kg) (for 0.1 hours) then NG-nitroarginine methyl ester (30 mg/kg) (for 0.3 hours) |
Ueno T, et al., Physiol Res 2003;52(6):689-700. |
kidney mass |
not specified |
days
| 9 |
serial mean |
6.84 |
g/kg |
|
|
post excision weight measurement |
|
0 |
|
|
|
65427 |
568 |
| MWF/FubRkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., J Am Soc Nephrol 2002 Nov;13(11):2706-14. |
kidney mass |
not specified |
126.0 days
| 8 |
|
5.01 |
g/kg |
0.36 |
1.02 |
post excision weight measurement |
|
0.0 |
|
|
|
67597 |
769 |
| SS.SR-(D3Arb14-D3Mco36)/Mco |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (0.3 %) (between 10 and 12 days) then controlled sodium content diet (2 %) (for 28 days) then controlled sodium content diet (4 %) (between 46 and 48 days) |
Cicila GT, et al., Hypertension. 2009 Apr;53(4):725-32. Epub 2009 Mar 2. |
kidney mass |
male |
114.0 days-118.0 days |
5 |
|
10.6 |
g/kg |
0.13 |
0.29 |
post excision weight measurement |
|
0 |
|
|
|
65126 |
283 |
| MWF/FubRkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. |
kidney mass |
female |
168.0 days
| 18 |
|
5.78 |
g/kg |
0.01 |
0.06 |
post excision weight measurement |
|
0.0 |
|
|
|
68171 |
309 |
| WAG/RijKyo |
both kidneys wet weight to body weight ratio |
control condition |
Redina OE, et al., Clin Exp Pharmacol Physiol. 2006 May-Jun;33(5-6):456-64. |
kidney mass |
not specified |
180.0 days
| 9 |
|
5.2 |
g/kg |
0.1 |
0.3 |
post excision weight measurement |
|
0.0 |
|
|
|
68057 |
835 |
| COP/OlaHsd |
both kidneys wet weight to body weight ratio |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
kidney mass |
not specified |
105.0 days
| 15 |
|
6.8 |
g/kg |
0.14 |
0.54 |
post excision weight measurement |
|
0.0 |
|
|
|
68521 |
933 |
| DA/OlaHsd |
both kidneys wet weight to body weight ratio |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
kidney mass |
not specified |
105.0 days
| 12 |
|
7.73 |
g/kg |
0.13 |
0.45 |
post excision weight measurement |
|
0.0 |
|
|
|
68522 |
933 |
| BXH2/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 18 |
|
6.3 |
g/kg |
0.1 |
0.42 |
post excision weight measurement |
|
0.0 |
|
|
|
97120 |
1858 |
| SHRSP/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| |
|
4.11 |
g/kg |
0.25 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102118 |
2646 |
| FHH-Nr4a1m1Mcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
56.0 days
| 6 |
|
10.3 |
g/kg |
0.14 |
0.34 |
post excision weight measurement |
|
0.0 |
|
|
|
99458 |
2318 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 7 |
|
6.81 |
g/kg |
0.19 |
0.5 |
post excision weight measurement |
|
0.0 |
|
|
|
103419 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
controlled hydrochlorothiazide content drinking water (15 mg/kg/d) (for 63 days) and hydralazine (75 mg/kg/d) (for 63 days) then controlled sodium content drinking water (2 %) (for 8 days) |
Naelten G, et al., J Cardiovasc Pharmacol. 2011 Feb;57(2):240-5. doi: 10.1097/FJC.0b013e318204bb7b. |
kidney mass |
male |
119.0 days
| 6 |
|
7.22 |
g/kg |
0.34 |
0.83 |
post excision weight measurement |
|
0.0 |
|
|
|
103422 |
2824 |
| LH/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (75 mg/kg) then hydralazine (75 mg/kg/d) (for 56 days) and controlled hydralazine content drinking water (15 mg/kg/d) (for 56 days) and reserpine (0.75 ml/kg/d) (for 56 days) |
Emonnot L, et al., Am J Hypertens. 2008 Jun;21(6):657-62. doi: 10.1038/ajh.2008.155. Epub 2008 Apr 3. |
kidney mass |
male |
112.0 days
| 7 |
|
8.05 |
g/kg |
0.24 |
0.63 |
post excision weight measurement |
|
0.0 |
|
|
|
102697 |
2703 |
| SHRSP.WKY-(D3Mgh16-rs197649383)/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| |
|
4.25 |
g/kg |
0.7 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102124 |
2646 |
| SBN/Ygl |
both kidneys wet weight to body weight ratio |
deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) and darusentan (50 mg/kg/d) (for 56 days) |
Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. |
kidney mass |
male |
16.0 days
| 8 |
|
3.2 |
g/kg |
0.06 |
0.17 |
post excision weight measurement |
|
0.0 |
|
n=8-15 |
|
106651 |
3035 |
| SS.LEW-(D10Chm224-D10Chm6)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 11 |
|
11.0 |
g/kg |
0.1 |
0.33 |
post excision weight measurement |
|
0 |
|
|
|
64770 |
226 |
| SS.LEW-(D18Rat61-D18Rat45)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 6 |
|
10.1 |
g/kg |
0.2 |
0.49 |
post excision weight measurement |
|
0 |
|
|
|
64776 |
226 |
| SS.LEW-(D17Chm9-D17Rat97)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 10 |
|
10.3 |
g/kg |
0.4 |
1.26 |
post excision weight measurement |
|
0 |
|
|
|
64777 |
226 |
| SS.LEW-(D8Chm14-D8Rat16)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 7 |
|
9.5 |
g/kg |
0.2 |
0.53 |
post excision weight measurement |
|
0 |
|
|
|
64789 |
226 |
| SS.LEW-(D10Rat27-Igfbp4)/Ayd |
both kidneys wet weight to body weight ratio |
controlled sodium content diet (2 %) (between 35 and 98 days) |
Duong C, et al., Mamm Genome 2006; 17(12): 1147-1161 |
kidney mass |
male |
98.0 days
| 7 |
|
10.9 |
g/kg |
0.4 |
1.06 |
post excision weight measurement |
|
0 |
|
|
|
64787 |
226 |
| SHR.BN-(D5Wox12-D5Wox20)/Ipcv |
both kidneys wet weight to body weight ratio |
control condition |
Pravenec M, et al., Physiol Res 2003;52(3):285-9. |
kidney mass |
male |
80.0 days-100.0 days |
8 |
|
6.9 |
g/kg |
0.24 |
0.68 |
post excision weight measurement |
|
0 |
|
|
|
65508 |
612 |
| MWF-Chr 6SHR/Rkb |
both kidneys wet weight to body weight ratio |
control condition |
Schulz A, et al., Clin Sci (Lond). 2007 Oct 22;. |
kidney mass |
female |
168.0 days
| 20 |
|
6.06 |
g/kg |
0.16 |
0.72 |
post excision weight measurement |
|
0.0 |
|
|
|
12764 |
309 |
| PXO6-2/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 8 |
|
5.6 |
g/kg |
0.1 |
0.28 |
post excision weight measurement |
|
0.0 |
|
|
|
97124 |
1858 |
| PXO2/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 11 |
|
5.7 |
g/kg |
0.1 |
0.33 |
post excision weight measurement |
|
0.0 |
|
|
|
97125 |
1858 |
| PXO5-1/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 11 |
|
5.8 |
g/kg |
0.1 |
0.33 |
post excision weight measurement |
|
0.0 |
|
|
|
97126 |
1858 |
| PXO10/Cub |
both kidneys wet weight to body weight ratio |
controlled sucrose content diet (70 % of calories) (between 0 and 168 hours) and controlled protein content diet (19.6 % of calories) (between 0 and 168 hours) and controlled fat content diet (10.4 % of calories) (between 0 and 168 hours) then fasting (between 0 and 16 hours) |
Hodulova M, et al., PLoS One. 2014 Oct 8;9(10):e109983. doi: 10.1371/journal.pone.0109983. eCollection 2014. |
kidney mass |
male |
127.0 days
| 12 |
|
7.3 |
g/kg |
0.1 |
0.35 |
post excision weight measurement |
|
0.0 |
|
|
|
97155 |
1858 |
| SHRSP.WKY-(D3Mgh16-D3Wox3)/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| 7 |
|
3.77 |
g/kg |
0.15 |
0.4 |
post excision weight measurement |
|
0.0 |
|
|
|
102161 |
2646 |
| WKY/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| |
|
2.87 |
g/kg |
0.23 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102119 |
2646 |
| SHRSP.WKY-(D3Mgh16-D3Rat80)/Gcrc |
both kidneys wet weight to body weight ratio |
vehicle control condition (for 126 days) then sodium chloride solution (1 %) (for 21 days) |
Koh-Tan HH, et al., J Hypertens. 2017 Feb;35(2):319-329. doi: 10.1097/HJH.0000000000001155. |
kidney mass |
male |
126.0 days
| |
|
3.77 |
g/kg |
0.12 |
|
post excision weight measurement |
|
0.0 |
|
|
|
102122 |
2646 |
| HTG |
both kidneys wet weight to body weight ratio |
losartan (10 mg/kg) (for 0.2 hours) then pentolinium (5 mg/kg) (for 0.1 hours) then NG-nitroarginine methyl ester (30 mg/kg) (for 0.3 hours) |
Ueno T, et al., Physiol Res 2003;52(6):689-700. |
kidney mass |
not specified |
days
| 10 |
continuous mean |
5.92 |
g/kg |
|
|
post excision weight measurement |
|
0 |
|
|
|
65418 |
568 |
| COP.DA-(D3Rat233-D3Mgh14)/Mco |
both kidneys wet weight to body weight ratio |
control condition |
Ways JA, et al., Physiol Genomics. 2006 Dec 19;. |
kidney mass |
not specified |
105.0 days
| 18 |
|
6.37 |
g/kg |
0.11 |
0.47 |
post excision weight measurement |
|
0.0 |
|
|
|
68524 |
933 |
| FHH/EurMcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
56.0 days
| 6 |
|
9.2 |
g/kg |
0.27 |
0.66 |
post excision weight measurement |
|
0.0 |
|
|
|
99457 |
2318 |
| FHH-Nr4a1m1Mcwi |
both kidneys wet weight to body weight ratio |
control condition |
Westbrook L, et al., J Am Soc Nephrol. 2014 Nov;25(11):2499-510. doi: 10.1681/ASN.2013070786. Epub 2014 Apr 10. |
kidney mass |
male |
168.0 days
| 6 |
|
11.0 |
g/kg |
0.53 |
1.3 |
post excision weight measurement |
|
0.0 |
|
|
|
99462 |
2318 |
| LL/Mav |
both kidneys wet weight to body weight ratio |
streptozotocin (100 mg/kg) |
Emonnot L, et al., J Hypertens. 2007 Feb;25(2):429-38. |
kidney mass |
male |
112.0 days
| 18 |
|
6.61 |
g/kg |
0.08 |
0.34 |
post excision weight measurement |
|
0.0 |
|
|
|
102763 |
2721 |
| SS-Kcnj1em1Kasu+/+ |
both kidneys wet weight to body weight ratio |
control condition (for 13 days) |
Zhou X, et al., Hypertension. 2013 Aug;62(2):288-94. doi: 10.1161/HYPERTENSIONAHA.111.01051. Epub 2013 Jun 10. |
kidney mass |
male |
13.0 days
| 6 |
|
8.6 |
g/kg |
1.1 |
2.69 |
post excision weight measurement |
|
0.0 |
|
|
|
104421 |
2948 |
| SS-Kcnj1em1Kasu+/- |
both kidneys wet weight to body weight ratio |
control condition (for 13 days) |
Zhou X, et al., Hypertension. 2013 Aug;62(2):288-94. doi: 10.1161/HYPERTENSIONAHA.111.01051. Epub 2013 Jun 10. |
kidney mass |
male |
13.0 days
| 6 |
|
8.8 |
g/kg |
0.4 |
0.98 |
post excision weight measurement |
|
0.0 |
|
|
|
104422 |
2948 |
| SBN/Ygl |
both kidneys wet weight to body weight ratio |
sham surgical control condition (for 56 days) and water (for 56 days) and standard rat chow (for 56 days) |
Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. |
kidney mass |
male |
16.0 days
| 8 |
|
2.4 |
g/kg |
0.03 |
0.08 |
post excision weight measurement |
|
0.0 |
|
n=8-15 |
|
106646 |
3035 |
| SBH/Ygl |
both kidneys wet weight to body weight ratio |
deoxycorticosterone acetate (75 mg) (for 56 days) and controlled sodium content drinking water (1 %) (for 56 days) |
Rothermund L, et al., Eur J Pharmacol. 2003 May 16;468(3):209-16. doi: 10.1016/s0014-2999(03)01714-x. |
kidney mass |
male |
16.0 days
| 8 |
|
3.0 |
g/kg |
0.08 |
0.23 |
post excision weight measurement |
|
0.0 |
|
n=8-15 |
|
106650 |
3035 |
| WKY/N |
both kidneys wet weight to body weight ratio |
control condition (between 42 and 77 days) |
Abrahamsen CT, etal., J Pharmacol Exp Ther. 2002 Apr;301(1):21-8. doi: 10.1124/jpet.301.1.21. |
kidney mass |
male |
126.0 days-182.0 days |
|
|
6.1 |
g/kg |
0.4 |
|
post excision weight measurement |
kidney |
0.0 |
|
|
|
107533 |
3090 |
| GK/MolTac |
both kidneys wet weight to body weight ratio |
control condition |
Schrijvers BF, etal., Nephrol Dial Transplant. 2004 May;19(5):1092-7. doi: 10.1093/ndt/gfh107. Epub 2004 Feb 19. |
kidney mass |
female |
420.0 days
| |
|
3.14 |
g/kg |
0.07 |
|
post excision weight measurement |
|
0.0 |
|
|
kidney weight, kidney weight to body weight ratio |
106953 |
3071 |