Phenominer Database Results (222 results)

 
 
Table "column sort" updates the order of the bars in the chart.
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Value Units SEM SD Individual Records Method Method Duration Post Insult Type Post Insult Time Value Post Insult Time Unit Method Notes Clinical Measurement Notes Experiment Notes Record ID Study ID
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 8.51 ng/ml/h 2.42 5.42 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51832 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 9 1.07 ng/ml/h 0.29 0.86 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51835 481
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 3 0.84 ng/ml/h 0.08 0.14 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51836 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 6 1.23 ng/ml/h 0.27 0.66 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51838 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 1.69 ng/ml/h 0.33 0.94 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51839 481
LEW/Crl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 4.91 ng/ml/h 0.65 1.44 Download Values radioimmunoassay 51958 481
FHH-Chr 6BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 6 3.2 ng/ml/h 0.43 1.06 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52889 482
FHH-Chr 8BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 2 2.11 ng/ml/h 0.7 0.98 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52891 482
FHH-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 1 1.4 ng/ml/h Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52893 482
FHH-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 4.81 ng/ml/h 0.78 2.07 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52895 482
FHH-Chr 3BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 3 1.53 ng/ml/h 1.17 2.02 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52901 482
FHH-Chr 14BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 2.19 ng/ml/h 0.69 1.83 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52902 482
FHH-Chr 4BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 4 4.38 ng/ml/h 1.19 2.38 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52908 482
FHH-Chr 1BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 3.1 ng/ml/h 0.58 1.53 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52907 482
FHH-Chr 11BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 3 1.02 ng/ml/h 0.4 0.69 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52912 482
FHH-Chr 4BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 11.17 ng/ml/h 2.91 8.22 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52911 482
FHH-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 4 2.48 ng/ml/h 0.69 1.38 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52921 482
SS-Chr 14BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 9 0.87 ng/ml/h 0.09 0.27 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52437 482
SS-Chr 6BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 1.2 ng/ml/h 0.42 1.18 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52443 482
SS-Chr 7BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 9 0.51 ng/ml/h 0.12 0.37 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52446 482
SS-Chr 3BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 0.42 ng/ml/h 0.07 0.2 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52455 482
SS-Chr YBN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 12 0.26 ng/ml/h 0.02 0.06 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52463 482
SS-Chr 11BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 14 0.34 ng/ml/h 0.09 0.33 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52462 482
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 9 0.75 ng/ml/h 0.15 0.45 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52464 482
SS-Chr 19BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 4 0.27 ng/ml/h 0.04 0.08 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52473 482
SS-Chr 4BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 1.23 ng/ml/h 0.24 0.64 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52476 482
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 1 0.67 ng/ml/h Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50539 481
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 6 2.26 ng/ml/h 0.6 1.47 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50570 481
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 3 7.64 ng/ml/h 1.68 2.91 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51015 481
Crl:CD(SD) plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 6 1.14 ng/ml/h 0.3 0.74 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51603 481
Hsd:SD plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 8 5.34 ng/ml/h 0.79 2.24 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51621 481
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 15 2.88 ng/ml/h 0.5 1.95 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50388 481
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 7 2.5 ng/ml/h 0.55 1.46 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50387 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 7 10.95 ng/ml/h 1.24 3.28 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50391 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 11.87 ng/ml/h 0.85 2.08 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50389 481
Crl:CD(SD) plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 5 5.64 ng/ml/h 1.41 3.16 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50413 481
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 0.7 ng/ml/h 0.15 0.42 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50455 481
SHR/NCrlCrlj plasma renin activity level unilateral nephrectomy (for 42 days) then controlled hydralazine content drinking water (15 mg/kg/d) (for 28 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. renin activity male 126.0 days 5 5.5 ng/ml/h 1.7 3.8 radioimmunoassay 0.0 unx 42 days 101265 2583
WKY plasma renin activity level controlled in utero environment (100 % of calories) (for 22 days) Riviere G, et al., Hypertension. 2005 Nov;46(5):1169-74. Epub 2005 Oct 3. renin activity male 112.0 days 5 0.43 ng/ml/h 0.05 0.11 enzyme or transport activity assay 0.0 99097 2218
WKY plasma renin activity level controlled enalapril content drinking water (50 mg/l) (between 63 and 77 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. renin activity male  days 12 206.8 ng/ml/h 20.7 71.71 radioimmunoassay 0.0 PA IV 50mg/kg 100426 2479
SHR/N-cp plasma renin activity level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. renin activity male 168.0 days-196.0 days 8 11.0 ng/ml/h 2.0 5.66 radioimmunoassay 0.0 101532 2601
SHR/N-cp plasma renin activity level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then controlled hydralazine content drinking water (30 mg/l) (between 84 and 98 days) and hydralazine (50 mg/l) (between 84 and 98 days) and reserpine (4 mg/l) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. renin activity male 140.0 days-168.0 days 8 38.0 ng/ml/h 2.0 5.66 radioimmunoassay 0.0 101534 2601
SHR/N-cp plasma renin activity level standard diet (between 28 and 42 days) then controlled carbohydrate content diet (54 %) (between 140 and 154 days) then perindopril (0.25-0.5 mg/kg/d) (between 84 and 98 days) Velasquez MT, et al., Hypertension. 1997 Nov;30(5):1232-7. renin activity male 168.0 days-196.0 days 8 52.0 ng/ml/h 8.0 22.63 radioimmunoassay 0.0 101533 2601
HsdCpb:WU plasma renin activity level control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. renin activity male 84.0 days 10 8.0 ng/ml/h 0.8 2.53 plasma renin activity assay 0.0 108877 3130
SS-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 12 0.38 ng/ml/h 0.04 0.14 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51837 481
SS-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 14 1.08 ng/ml/h 0.12 0.45 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51840 481
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 1.48 ng/ml/h 0.33 0.74 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51845 481
SS-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 10 0.58 ng/ml/h 0.14 0.43 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51842 481
LEW/Crl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 4 4.31 ng/ml/h 1.53 3.06 Download Values radioimmunoassay 51959 481
FHH-Chr 12BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 7.44 ng/ml/h 1.44 3.8 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52878 482
FHH/EurMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 14 6.0 ng/ml/h 0.7 2.62 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52881 482
FHH-Chr 14BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 5 4.35 ng/ml/h 1.32 2.96 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52886 482
FHH-Chr 6BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 9 2.67 ng/ml/h 0.6 1.81 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52887 482
FHH/EurMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 38 2.57 ng/ml/h 0.36 2.21 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52899 482
FHH-Chr 7BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 1.89 ng/ml/h 0.44 1.17 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52916 482
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 0.26 ng/ml/h 0.03 0.08 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52918 482
FHH-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 4 4.64 ng/ml/h 0.91 1.82 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52915 482
SS-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 0.29 ng/ml/h 0.04 0.13 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52439 482
SS-Chr 5BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 0.44 ng/ml/h 0.08 0.2 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52448 482
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 0.91 ng/ml/h 0.2 0.58 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52452 482
SS-Chr 15BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 3 1.73 ng/ml/h 0.2 0.35 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52454 482
SS-Chr 13BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 17 0.43 ng/ml/h 0.09 0.35 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52461 482
SS-Chr 1BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 16 0.49 ng/ml/h 0.07 0.29 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52466 482
SS-Chr 19BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 0.66 ng/ml/h 0.09 0.25 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52475 482
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 1.01 ng/ml/h 0.15 0.43 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52480 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 18 0.66 ng/ml/h 0.14 0.58 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52478 482
LE/BluGill plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 3.46 ng/ml/h 1.44 4.09 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52578 482
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 5 0.3 ng/ml/h 0.03 0.07 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50535 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 9.02 ng/ml/h 1.47 3.59 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50537 481
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 5 2.8 ng/ml/h 0.87 1.94 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50565 481
WKY/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 3.33 ng/ml/h 1.41 3.46 Download Values radioimmunoassay 50715 481
Hsd:SD plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 12 8.82 ng/ml/h 1.04 3.62 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50896 481
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 3 1.67 ng/ml/h 0.55 0.96 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51006 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 3.33 ng/ml/h 0.45 1.11 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51011 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 4 7.2 ng/ml/h 1.34 2.68 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51013 481
Crl:CD(SD) plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 1.32 ng/ml/h 0.64 1.42 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51605 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 3 7.09 ng/ml/h 3.05 5.29 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50392 481
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 9 3.86 ng/ml/h 0.51 1.54 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50395 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 9.13 ng/ml/h 0.66 1.87 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50396 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 9 11.85 ng/ml/h 0.69 2.08 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50394 481
F344/DuCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 8 10.84 ng/ml/h 1.35 3.83 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50416 481
Crl:CD(SD) plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 2 5.07 ng/ml/h 0.24 0.33 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50415 481
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 1.22 ng/ml/h 0.11 0.31 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50461 481
SHR/NCrlCrlj plasma renin activity level unilateral nephrectomy (for 42 days) then controlled delapril content drinking water (30 mg/kg/d) (for 28 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. renin activity male 126.0 days 9 5.1 ng/ml/h 0.5 1.5 radioimmunoassay 0.0 unx 42 days 101264 2583
SD plasma renin activity level sham surgical control condition (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. renin activity male  days 6 3.1 ng/ml/h 0.29 0.7 radioimmunoassay 0.0 sham unx 13 days 101563 2602
WKY plasma renin activity level puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. renin activity male  days 12 7.4 ng/ml/h 0.8 2.77 radioimmunoassay 0.0 PA IV 50mg/kg 100425 2479
BN/NHsdMcwi plasma renin activity level controlled sodium chloride content drinking water (1 %) (for 7 days) then controlled sodium chloride content drinking water (2 %) (for 7 days) then controlled sodium chloride content drinking water (1 %) (for 9 days) then water (for 12 days) Gilibert S, et al., J Hypertens. 2009 Jun;27(6):1186-93. renin activity male 175.0 days 10 24.6 ng/ml/h 2.51 7.94 plasma renin activity assay 0.0 102076 2645
LH-Chr 13BN/Mav plasma renin activity level controlled sodium chloride content drinking water (1 %) (for 7 days) then controlled sodium chloride content drinking water (2 %) (for 7 days) then controlled sodium chloride content drinking water (1 %) (for 9 days) then water (for 12 days) Gilibert S, et al., J Hypertens. 2009 Jun;27(6):1186-93. renin activity male 175.0 days 10 12.19 ng/ml/h 1.15 3.64 plasma renin activity assay 0.0 102078 2645
SR/NEisSlc plasma renin activity level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. renin activity male 91.0 days 6 3.23 ng/ml/h 0.45 1.11 radioimmunoassay 0.0 100689 2519
SS/NEisSlc plasma renin activity level controlled sodium content diet (0.3 %) (for 91 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. renin activity male 91.0 days 6 2.49 ng/ml/h 0.63 1.53 radioimmunoassay 0.0 100688 2519
SS/NEisSlc plasma renin activity level controlled sodium content diet (8 %) (for 42 days) then candesartan (1 mg/kg/d) (for 42 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. renin activity male 91.0 days 6 8.35 ng/ml/h 2.34 5.73 radioimmunoassay 0.0 100691 2519
MW plasma renin activity level nephrectomy (for 28 days) then enalapril (50 mg/l) (for 21 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. renin activity male  days 7 194.5 ng/ml/h 28.0 74.08 radioimmunoassay 0.0 5/6 nephrectomy 28 days 101045 2561
MW plasma renin activity level nephrectomy (for 28 days) then reserpine (5 mg/l) (for 21 days) and hydralazine (80 mg/l) (for 21 days) and controlled hydralazine content drinking water (25 mg/l) (for 21 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. renin activity male  days 7 21.9 ng/ml/h 2.5 6.61 radioimmunoassay 0.0 5/6 nephrectomy 28 days 101046 2561
MWF/Hsd plasma renin activity level control condition Szymanski MK, etal., Basic Res Cardiol. 2012 Mar;107(2):242. doi: 10.1007/s00395-011-0242-4. Epub 2012 Jan 19. renin activity male 84.0 days 10 4.4 ng/ml/h 0.5 1.58 plasma renin activity assay 0.0 108876 3130
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 95.0 days 7 4.7 ng/ml/h 1.6 4.23 ex vivo blood analysis 0 65473 151
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 95.0 days 11 9.6 ng/ml/h 1.0 3.32 ex vivo blood analysis 0 65474 151
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 13 0.43 ng/ml/h 0.08 0.29 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51833 481
FHH-Chr 15BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 9 2.92 ng/ml/h 0.71 2.13 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52879 482
FHH-Chr 5BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 1.16 ng/ml/h 0.33 0.88 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52890 482
FHH-Chr 19BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 4.98 ng/ml/h 0.69 1.82 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52888 482
FHH-Chr 13BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 8.07 ng/ml/h 0.72 1.91 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52892 482
FHH-Chr 15BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 2.41 ng/ml/h 0.58 1.53 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52900 482
FHH-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 6.16 ng/ml/h 1.63 4.32 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52906 482
FHH-Chr 17BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 0.68 ng/ml/h 0.16 0.42 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52909 482
FHH-Chr XBN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 6 2.25 ng/ml/h 0.51 1.25 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52913 482
FHH-Chr 11BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 5 5.01 ng/ml/h 2.7 6.04 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52914 482
FHH-Chr 10BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 4 1.23 ng/ml/h 0.39 0.78 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52917 482
FHH-Chr 1BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 9 3.7 ng/ml/h 0.8 2.4 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52924 482
SS-Chr 10BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 10 0.93 ng/ml/h 0.12 0.39 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52435 482
SS-Chr 6BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 6 3.55 ng/ml/h 1.2 2.94 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52438 482
SS-Chr 10BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 3.82 ng/ml/h 0.85 2.41 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52444 482
SS-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 1.44 ng/ml/h 0.35 0.98 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52442 482
SS-Chr 3BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 5 2.16 ng/ml/h 0.15 0.33 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52458 482
SS-Chr 13BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 17 1.13 ng/ml/h 0.29 1.2 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52457 482
SS-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 0.42 ng/ml/h 0.09 0.25 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52459 482
SS-Chr 12BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 0.29 ng/ml/h 0.05 0.14 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52474 482
SS-Chr 2BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 10 0.99 ng/ml/h 0.13 0.43 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52477 482
SS-Chr 2BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 9 0.58 ng/ml/h 0.1 0.29 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52483 482
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 3 0.64 ng/ml/h 0.27 0.47 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50536 481
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 6 0.77 ng/ml/h 0.33 0.8 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50540 481
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 12 1.15 ng/ml/h 0.27 0.94 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51003 481
SS-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 14 2.21 ng/ml/h 0.35 1.3 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51010 481
F344/DuCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 7 3.27 ng/ml/h 0.47 1.25 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51604 481
F344/DuCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 8 2.16 ng/ml/h 0.24 0.68 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 51606 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 11.16 ng/ml/h 0.5 1.41 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50397 481
F344/DuCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 7 15.17 ng/ml/h 1.06 2.81 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Teklad upon arrival at MCW. For rats received from CRL and Harlan 50414 481
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 14 0.93 ng/ml/h 0.15 0.56 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50456 481
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 7 1.67 ng/ml/h 0.24 0.62 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50463 481
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 92.0 days 14 1.4 ng/ml/h 0.4 1.5 ex vivo blood analysis enzyme assay 13308 151
Crl:WI plasma renin activity level control condition Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. renin activity male 112.0 days 10 2.8 ng/ml/h 0.7 2.21 radioimmunoassay 0.0 102946 2783
GK/MolTac plasma renin activity level control condition Korkmaz-Ic�z S, et al., Am J Physiol Heart Circ Physiol. 2016 Oct 1;311(4):H958-H971. doi: 10.1152/ajpheart.00956.2015. Epub 2016 Aug 12. renin activity male 112.0 days 8 4.8 ng/ml/h 1.9 5.37 radioimmunoassay 0.0 102947 2783
SHR/NCrlCrlj plasma renin activity level unilateral nephrectomy (for 42 days) then controlled candesartan content drinking water (1 mg/kg/d) (for 28 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. renin activity male 126.0 days 8 9.8 ng/ml/h 1.7 4.81 radioimmunoassay 0.0 unx 42 days 101263 2583
WKY plasma renin activity level controlled in utero environment (30 % of calories) (for 22 days) Riviere G, et al., Hypertension. 2005 Nov;46(5):1169-74. Epub 2005 Oct 3. renin activity male 112.0 days 6 0.48 ng/ml/h 0.08 0.2 enzyme or transport activity assay 0.0 99098 2218
LH/Mav plasma renin activity level controlled sodium chloride content drinking water (1 %) (for 7 days) then controlled sodium chloride content drinking water (2 %) (for 7 days) then controlled sodium chloride content drinking water (1 %) (for 9 days) then water (for 12 days) Gilibert S, et al., J Hypertens. 2009 Jun;27(6):1186-93. renin activity male 175.0 days 10 11.62 ng/ml/h 2.24 7.08 plasma renin activity assay 0.0 102077 2645
WKY plasma renin activity level puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. renin activity male  days 11 8.8 ng/ml/h 1.0 3.32 radioimmunoassay 0.0 PA IV 50mg/kg 23 days 100422 2479
SS/NEisSlc plasma renin activity level controlled sodium content diet (8 %) (for 42 days) then 0.9% sodium chloride solution (0.3 ml) (for 42 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. renin activity male 91.0 days 12 3.6 ng/ml/h 1.32 4.57 radioimmunoassay 0.0 100687 2519
MW plasma renin activity level sham surgical control condition (for 28 days) Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. renin activity male  days 7 9.1 ng/ml/h 0.5 1.32 radioimmunoassay 0.0 sham surgery 28 days 101043 2561
MW plasma renin activity level nephrectomy (for 28 days) then control condition Anderson S, et al., J Clin Invest. 1986 Jun;77(6):1993-2000. renin activity male  days 7 3.8 ng/ml/h 0.7 1.85 radioimmunoassay 0.0 5/6 nephrectomy 28 days 101044 2561
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 3 2.06 ng/ml/h 0.69 1.19 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51844 481
WKY/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 6.96 ng/ml/h 0.75 2.12 Download Values radioimmunoassay 51957 481
WKY/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 6.9 ng/ml/h 2.37 5.82 Download Values radioimmunoassay 51960 481
FHH-Chr 2BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 5 0.4 ng/ml/h 0.07 0.16 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52885 482
FHH-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 6 3.02 ng/ml/h 0.98 2.41 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52896 482
FHH-Chr 10BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 4.33 ng/ml/h 0.93 2.46 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52905 482
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 7 1.61 ng/ml/h 0.88 2.33 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52919 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 1.01 ng/ml/h 0.34 0.95 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52440 482
SS-Chr 14BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 0.42 ng/ml/h 0.1 0.29 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52441 482
SS-Chr 7BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 11 1.31 ng/ml/h 0.26 0.87 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52449 482
SS-Chr 17BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 6 0.92 ng/ml/h 0.24 0.6 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52447 482
SS-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 1.66 ng/ml/h 0.38 1.07 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52451 482
SS-Chr 5BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 6 0.68 ng/ml/h 0.33 0.8 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52450 482
SS-Chr 15BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 0.28 ng/ml/h 0.02 0.05 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52453 482
SS-Chr XBN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 3 1.82 ng/ml/h 0.72 1.25 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52467 482
SS-Chr 1BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 14 0.67 ng/ml/h 0.2 0.76 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52469 482
SS-Chr 4BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 0.5 ng/ml/h 0.14 0.36 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52470 482
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 9 1.17 ng/ml/h 0.22 0.66 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52471 482
SS-Chr 12BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 5 0.88 ng/ml/h 0.15 0.33 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52479 482
SS-Chr XBN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 4 1.04 ng/ml/h 0.33 0.65 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52482 482
LE/BluGill plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 6 4.74 ng/ml/h 1.34 3.27 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 52579 482
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 6 7.97 ng/ml/h 1.02 2.5 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50541 481
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 2 1.95 ng/ml/h 0.95 1.34 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50566 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 13.14 ng/ml/h 1.17 2.86 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50567 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 4 12.93 ng/ml/h 1.15 2.3 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50571 481
LEW/Crl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 2.17 ng/ml/h 0.86 2.11 Download Values radioimmunoassay 50713 481
WKY/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 9 0.76 ng/ml/h 0.14 0.41 Download Values radioimmunoassay 50712 481
LEW/Crl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 4 1.36 ng/ml/h 0.42 0.83 Download Values radioimmunoassay 50714 481
SS-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 11 3.37 ng/ml/h 0.66 2.2 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51004 481
SS-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 9 1.9 ng/ml/h 0.26 0.78 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51012 481
Hsd:SD plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 5 1.65 ng/ml/h 0.44 0.98 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 51620 481
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 2.08 ng/ml/h 0.23 0.56 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50458 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 3 1.99 ng/ml/h 0.5 0.87 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50460 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 7 0.9 ng/ml/h 0.26 0.68 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50459 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 1.93 ng/ml/h 0.26 0.74 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50465 481
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 92.0 days 7 2.2 ng/ml/h 0.58 1.53 ex vivo blood analysis 0.0 enzyme assay 13307 151
BN-Chr 13LH/MavRrrc plasma renin activity level controlled sodium chloride content drinking water (1 %) (for 7 days) then controlled sodium chloride content drinking water (2 %) (for 7 days) then controlled sodium chloride content drinking water (1 %) (for 9 days) then water (for 12 days) Gilibert S, et al., J Hypertens. 2009 Jun;27(6):1186-93. renin activity male 175.0 days 9 24.33 ng/ml/h 2.53 7.59 plasma renin activity assay 0.0 102079 2645
SS-Chr 20BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 9 1.75 ng/ml/h 0.31 0.92 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51834 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 0.65 ng/ml/h 0.25 0.6 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51841 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 5 4.01 ng/ml/h 1.09 2.43 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51843 481
FHH-Chr 8BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 2 3.48 ng/ml/h 1.03 1.46 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52880 482
FHH-Chr 19BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 2.2 ng/ml/h 0.96 2.54 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52882 482
FHH-Chr 3BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 1 1.17 ng/ml/h Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52883 482
FHH-Chr 5BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 5 2.6 ng/ml/h 0.56 1.25 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52884 482
FHH-Chr 13BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 10 4.42 ng/ml/h 0.78 2.47 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52894 482
FHH-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 10.07 ng/ml/h 1.37 3.87 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52898 482
FHH-Chr 12BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 10 1.71 ng/ml/h 0.17 0.52 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52897 482
FHH-Chr 2BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 4 1.73 ng/ml/h 0.23 0.46 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52904 482
FHH-Chr YBN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 4 2.47 ng/ml/h 0.64 1.27 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52903 482
FHH-Chr 17BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 11 4.02 ng/ml/h 0.58 1.93 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52910 482
FHH-Chr XBN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 5 4.63 ng/ml/h 0.97 2.16 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52920 482
FHH-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 7 4.85 ng/ml/h 1.02 2.7 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52923 482
FHH-Chr 7BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) and controlled NG-nitroarginine methyl ester content drinking water (12.5 mg/l) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 1.15 ng/ml/h 0.48 1.35 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52922 482
SS.BN-(D12Arb13-D12Rat79)/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 9 0.49 ng/ml/h 0.16 0.49 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52436 482
SS-Chr 17BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 8 0.36 ng/ml/h 0.08 0.22 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52445 482
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 9 0.41 ng/ml/h 0.15 0.44 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52456 482
SS-Chr 11BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 14 1.11 ng/ml/h 0.26 0.96 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52460 482
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity male 80.0 days-99.0 days 55 0.68 ng/ml/h 0.12 0.9 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52465 482
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 8 1.04 ng/ml/h 0.18 0.51 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52468 482
SS.BN-(D8Rat163-D8Rat81)/Mcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 10 1.79 ng/ml/h 0.42 1.31 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52472 482
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (8 %) (between 19 and 22 days) PhysGen Renal B data renin activity female 80.0 days-99.0 days 15 4.4 ng/ml/h 1.26 4.87 Download Values radioimmunoassay Moms were fed Teklad, pups used in studies were fed Dyets 52481 482
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 1.57 ng/ml/h 0.07 0.16 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50538 481
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 3.3 ng/ml/h 0.43 0.97 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50568 481
SS-Chr 18BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 2 1.29 ng/ml/h 0.49 0.69 Download Values radioimmunoassay Conversion period. Moms had mixed diet, Dyets and Teklad, for 3-4 weeks. Whatever Mom was fed, so were pups. Whatever pups were fed in the barrier, they continued with through the study. Possible maternal influence on pups estimated at 10 weeks 50569 481
Hsd:SD plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 6.46 ng/ml/h 0.58 1.64 Download Values radioimmunoassay Moms were fed vendors standard diet, pups were fed Dyets upon arrival at MCW. For rats received from Harlan 50895 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 12.61 ng/ml/h 1.89 4.23 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51002 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 9 3.39 ng/ml/h 0.88 2.65 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51005 481
SS-Chr 9BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 11 0.91 ng/ml/h 0.18 0.59 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51007 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 5 6.62 ng/ml/h 1.19 2.66 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51008 481
GH/OmrMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 7 4.42 ng/ml/h 0.57 1.51 Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51009 481
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 1 8.99 ng/ml/h Download Values radioimmunoassay Moms and pups used in studies were fed Teklad 51014 481
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 5 5.67 ng/ml/h 1.28 2.87 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50390 481
SS-Chr 16BN/Mcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) then furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 2 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 3.34 ng/ml/h 0.14 0.39 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50393 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity female 87.0 days-120.0 days 6 9.06 ng/ml/h 1.26 3.08 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50457 481
FHH/EurMcwi plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 8 9.0 ng/ml/h 0.76 2.15 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50462 481
SHR/NCrl plasma renin activity level controlled sodium content diet (4 %) (between 17 and 36 days) PhysGen Renal A data renin activity male 87.0 days-120.0 days 7 0.83 ng/ml/h 0.23 0.6 Download Values radioimmunoassay Moms and pups used in studies were fed Dyets 50464 481
SHR/NCrlCrlj plasma renin activity level unilateral nephrectomy (for 42 days) Kohara K, et al., Hypertension. 1993 Jun;21(6 Pt 2):975-9. renin activity male 126.0 days 5 1.3 ng/ml/h 0.2 0.45 radioimmunoassay 0.0 unx 42 days 101262 2583
SD plasma renin activity level unilateral nephrectomy (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. renin activity male  days 11 4.3 ng/ml/h 0.63 2.08 radioimmunoassay 0.0 unx 13 days - 101564 2602
SD plasma renin activity level unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. renin activity male  days 5 13.3 ng/ml/h 5.5 12.3 radioimmunoassay 0.0 unx 13 days 101565 2602
SD plasma renin activity level unilateral nephrectomy (between 12 and 14 days) then enalapril (50 mg/l) (between 12 and 14 days) and losartan (180 mg/l) (between 12 and 14 days) and aldosterone (30-40 mg/kg/d) (between 12 and 14 days) Greene EL, et al., J Clin Invest. 1996 Aug 15;98(4):1063-8. renin activity male  days 5 5.2 ng/ml/h 2.24 5.0 radioimmunoassay 0.0 unx 13 days 101566 2602
WKY plasma renin activity level 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. renin activity male  days 10 10.7 ng/ml/h 1.7 5.38 radioimmunoassay 0.0 100421 2479
WKY plasma renin activity level controlled enalapril content drinking water (50 mg/l) (for 30 days) then puromycin aminonucleoside (50 mg/kg) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. renin activity male  days 10 100.3 ng/ml/h 18.6 58.82 radioimmunoassay 0.0 PA IV 50mg/kg 23 days 100423 2479
WKY plasma renin activity level 0.9% sodium chloride solution (3 ml) Anderson S, et al., J Clin Invest. 1988 Nov;82(5):1757-68. renin activity male  days 11 11.9 ng/ml/h 1.0 3.32 radioimmunoassay 0.0 100424 2479
SS/NEisSlc plasma renin activity level controlled sodium content diet (8 %) (for 42 days) then cilazapril (10 mg/kg/d) (for 42 days) Otsuka F, et al., Am J Physiol. 1998 Jun;274(6 Pt 2):R1797-806. renin activity male 91.0 days 6 5.72 ng/ml/h 1.36 3.33 radioimmunoassay 0.0 100690 2519