control condition (between 42 and 77 days)

 cyclosporine A (50 mg/kg/d) (for 7 days)

 enalapril (50 mg/l) (for 182 days)

 enalapril (50 mg/l) (for 60 days)

 controlled NG-nitroarginine methyl ester content drinking water (5 mg/kg/d) (for 42 days)

 controlled lisinopril content drinking water (40 mg/l) (between 35 and 56 days)

 vehicle control condition

 controlled sodium content diet (0.3 %) (for 91 days)

 controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and vehicle control condition (between 42 and 77 days)

 standard diet

 controlled sodium content diet (8 %) (for 42 days) then 0.9% sodium chloride solution (0.3 ml) (for 42 days)

 control condition

 control condition (for 84 days)

 controlled sodium content diet (8 %) (for 42 days) then candesartan (1 mg/kg/d) (for 42 days)

 reproduction condition

 controlled sodium content diet (0.3 %) (for 49 days) then controlled sodium content diet (8 %) (for 42 days) then cilazapril (10 mg/kg/d) (for 42 days)

 castor oil (for 7 days)

 controlled sodium chloride content diet (8 %) (for 56 days)

 cyclosporine A (50 mg/kg/d) (for 7 days) and lacidipine (1 mg/kg/d) (for 7 days)

 monocrotaline (40 mg/kg)

 controlled sodium chloride content drinking water (1 %) (between 42 and 77 days) and controlled fat content diet (24.5 %) (between 42 and 77 days) and eprosartan (60 mg/kg/d) (between 42 and 77 days)