Phenominer Database Results (152 results)

 
 
How to display a graph
Strain Phenotype Conditions Study Experiment Name Sex Age # of Animals Average Type Value Units SEM SD Method Method Site Method Duration Post Insult Time Value Method Notes Clinical Measurement Notes Record ID Study ID
BN/NHsdMcwi absolute change in mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 20 serial mean 25.0 mmHg 3.0 13.42 vascular indwelling catheter method left femoral artery 0.0 67303 151
SS/JrHsdMcwi absolute change in mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 9 serial mean 24.0 mmHg 4.0 12.0 vascular indwelling catheter method left femoral artery 0.0 67304 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 93.0 days 12 serial mean 427.0 beats/min 6.0 20.78 vascular indwelling catheter method left femoral artery 0 65469 151
SS/JrHsdMcwi body weight controlled sodium content diet (0.4 %) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. body mass female 84.0 days 28 230.0 g 3.0 15.87 body weighing method 0.0 after catheterization and jacket attachment 67294 151
SS/JrHsdMcwi plasma total cholesterol level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood cholesterol amount female 92.0 days-94.0 days 12 76.0 mg/dl 4.4 15.24 plasma total cholesterol measurement test 0.0 67290 151
SS/JrHsdMcwi absolute change in mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 34.0 mmHg 3.0 10.82 vascular indwelling catheter method left femoral artery 0.0 67300 151
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 130.0 mmHg 4.0 18.33 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11849 151
BN/NHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 92.0 mmHg 3.0 13.75 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11851 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (for 21 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 89.0 days-92.0 days 20 serial mean 437.0 beats/min 6.0 26.83 vascular indwelling catheter method left femoral artery 13310 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 111.8 mmHg 3.9 17.87 vascular indwelling catheter method left femoral artery 120.0 69527 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 160.2 mmHg 3.5 12.62 vascular indwelling catheter method left femoral artery 120.0 69534 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (100 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 147.2 mmHg 3.9 14.06 vascular indwelling catheter method left femoral artery 120.0 69532 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 128.6 mmHg 4.0 18.33 vascular indwelling catheter method left femoral artery 120.0 69537 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 20 serial mean 135.6 mmHg 3.2 14.31 vascular indwelling catheter method left femoral artery 120.0 69539 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then acetylcholine (0.2 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 16 serial mean 118.6 mmHg 3.4 13.6 vascular indwelling catheter method left femoral artery 120.0 69543 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) then acetylcholine (0.1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 138.6 mmHg 3.8 17.41 vascular indwelling catheter method left femoral artery 120.0 69547 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) then acetylcholine (0.2 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 9 serial mean 159.1 mmHg 6.4 19.2 vascular indwelling catheter method left femoral artery 120.0 69550 151
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 92.0 days-94.0 days 14 0.56 mEq/d 0.06 0.21 unspecified method 0.0 urine sodium analysis umol/min 69469 151
BN/NHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 25 56.4 mg/dl 4.95 24.75 urine creatinine analysis 0.0 69475 151
BN/NHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 25 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 mg/min 69477 151
SS/JrHsdMcwi urine potassium excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine potassium amount female 92.0 days-94.0 days 14 0.92 mEq/d 0.07 0.27 unspecified method 0.0 urine potassium analysis umol/min 69474 151
BN/NHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 92.0 days-94.0 days 8 1.1 ml/min 0.2 0.57 urine creatinine analysis 0.0 mg/min 69479 151
BN/NHsdMcwi hematocrit controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. erythrocyte quantity female 89.0 days-92.0 days 15 41.6 % 0.4 1.55 hematocrit analysis 0.0 69481 151
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 92.0 days-94.0 days 10 1.08 ml/min 0.37 1.17 urine creatinine analysis 0.0 mg/min 69480 151
SS/JrHsdMcwi white blood cell count controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. leukocyte quantity female 92.0 days-94.0 days 9 0.01 x 1000 cells/ul 1044.0 3132.0 isolated cell counting method 0.0 69496 151
BN/NHsdMcwi plasma high density lipoprotein cholesterol level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood HDL cholesterol amount female 92.0 days-94.0 days 9 44.2 mg/dl 2.2 6.6 plasma high-density lipoprotein-cholesterol measurement test 0.0 69503 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days 16 serial mean 208.0 mmHg 7.6 30.4 vascular indwelling catheter method left femoral artery 10800.0 69510 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 94.0 days 11 serial mean 182.9 mmHg 4.1 13.6 vascular indwelling catheter method left femoral artery 10800.0 69522 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 93.0 days 11 serial mean 446.8 beats/min 9.7 32.17 vascular indwelling catheter method left femoral artery 10800.0 69520 151
SS/JrHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 93.0 days 10 serial mean 146.5 mmHg 5.6 17.71 vascular indwelling catheter method left femoral artery 10800.0 69518 151
BN/NHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 94.0 days 17 serial mean 91.6 mmHg 3.6 14.84 vascular indwelling catheter method left femoral artery 10800.0 69523 151
BN/NHsdMcwi body weight controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) and controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. body mass female 89.0 days-92.0 days 24 168.0 g 2.3 11.27 body weighing method 0.0 69439 151
SS/JrHsdMcwi body weight controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) and controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. body mass female 84.0 days 28 221.0 g 2.7 14.29 body weighing method 0.0 69442 151
SS/JrHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 15 serial mean 139.0 mmHg 6.0 23.24 vascular indwelling catheter method left femoral artery 0.0 69446 151
BN/NHsdMcwi urine sodium level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 89.0 days-92.0 days 24 370.0 mmol/l 14.3 70.06 unspecified method 0.0 urine sodium analysis 69453 151
BN/NHsdMcwi urine potassium excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine potassium amount female 89.0 days-92.0 days 24 0.96 mEq/d 0.04 0.21 unspecified method 0.0 urine potassium analysis 69461 151
SS/JrHsdMcwi urine total protein level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (0.4 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. total urine protein amount female 90.0 days-94.0 days 18 2.63 mg/ml 0.47 1.99 urine total protein analysis 0.0 mg/ml 69458 151
BN/NHsdMcwi body weight controlled sodium content diet (0.4 %) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. body mass female 84.0 days 33 175.0 g 3.0 17.23 body weighing method 0.0 after catheterization and jacket attachment 67293 151
BN/NHsdMcwi heart wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart mass female 97.0 days-101.0 days 27 0.69 g 0.02 0.1 post excision weight measurement 0.0 67295 151
BN/NHsdMcwi plasma triglyceride level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood triglyceride amount female 92.0 days-94.0 days 7 0.72 mmol/l 0.11 0.3 plasma triglyceride analysis 0.0 67291 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 174.0 mmHg 6.0 27.5 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11854 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (100 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 132.9 mmHg 3.8 17.41 vascular indwelling catheter method left femoral artery 120.0 69531 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (0.5 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 120.4 mmHg 5.3 24.29 vascular indwelling catheter method left femoral artery 120.0 69535 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) then acetylcholine (0.1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 9 serial mean 160.0 mmHg 6.7 20.1 vascular indwelling catheter method left femoral artery 120.0 69548 151
SS/JrHsdMcwi urine sodium level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 92.0 days-94.0 days 14 149.5 mmol/l 5.2 19.46 unspecified method 0.0 urine sodium analysis 69467 151
BN/NHsdMcwi urine potassium excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine potassium amount female 92.0 days-94.0 days 22 0.88 mEq/d 0.06 0.27 unspecified method 0.0 urine potassium analysis umol/min 69473 151
BN/NHsdMcwi plasma total protein level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood total protein amount female 89.0 days-92.0 days 13 38.6 mg/ml 2.0 7.21 unspecified method 0.0 69483 151
SS/JrHsdMcwi right kidney wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney mass female 97.0 days-101.0 days 21 1.32 g 0.08 0.37 post excision weight measurement 0.0 69508 151
SS/JrHsdMcwi plasma high density lipoprotein cholesterol level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood HDL cholesterol amount female 92.0 days-94.0 days 12 68.1 mg/dl 4.5 15.59 plasma high-density lipoprotein-cholesterol measurement test 0.0 69504 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 92.0 days 21 serial mean 425.4 beats/min 10.5 48.12 vascular indwelling catheter method left femoral artery 10800.0 69514 151
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 93.0 days 21 serial mean 127.2 mmHg 4.1 18.79 vascular indwelling catheter method left femoral artery 10800.0 69515 151
BN/NHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 93.0 days 21 serial mean 89.6 mmHg 2.5 11.46 vascular indwelling catheter method left femoral artery 10800.0 69517 151
SS/JrHsdMcwi body weight controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) and controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. body mass female 89.0 days-92.0 days 16 211.0 g 6.0 24.0 body weighing method 0.0 69440 151
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 20 serial mean 111.0 mmHg 2.7 12.07 vascular indwelling catheter method left femoral artery 0.0 69447 151
BN/NHsdMcwi timed urine volume controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine output female 89.0 days-92.0 days 25 35.0 ml/d 2.0 10.0 urine volume measurement method 0.0 69451 151
BN/NHsdMcwi urine total protein level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (0.4 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. total urine protein amount female 90.0 days-94.0 days 20 0.24 mg/ml 0.05 0.22 urine total protein analysis 0.0 mg/ml 69457 151
SS/JrHsdMcwi absolute change in mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 39.0 mmHg 6.0 21.63 vascular indwelling catheter method left femoral artery 0.0 67302 151
BN/NHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) then tactile electric shock exposure (2 %) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 14 serial mean 16.0 mmHg 3.0 11.22 vascular indwelling catheter method left femoral artery 0 66149 151
BN/NHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 14 serial mean 72.0 mmHg 2.0 7.48 vascular indwelling catheter method left femoral artery 0 65464 151
SS/JrHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 12 serial mean 126.0 mmHg 5.0 17.32 vascular indwelling catheter method left femoral artery 0 65465 151
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 14 serial mean 89.0 mmHg 2.0 7.48 vascular indwelling catheter method left femoral artery 0 65466 151
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 95.0 days 7 4.7 ng/ml/h 1.6 4.23 ex vivo blood analysis 0 65473 151
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 95.0 days 11 9.6 ng/ml/h 1.0 3.32 ex vivo blood analysis 0 65474 151
BN/NHsdMcwi urine total protein excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. total urine protein amount female 90.0 days-94.0 days 20 8.6 mg/d 2.2 9.84 urine total protein analysis 0 66151 151
SS/JrHsdMcwi plasma creatinine level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood creatinine amount female 90.0 days-94.0 days 15 0.7 mg/dl 0.1 0.39 plasma creatinine analysis 0.0 plasma creatinine analysis 67282 151
SS/JrHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 90.0 days-94.0 days 13 1.2 ml/min 0.2 0.72 urine creatinine analysis 0.0 plasma creatinine analysis 67284 151
SS/JrHsdMcwi heart wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart mass female 97.0 days-101.0 days 21 1.03 g 0.05 0.23 post excision weight measurement 0.0 plasma creatinine analysis 67296 151
BN/NHsdMcwi ratio of change in renal blood flow rate to kidney weight controlled sodium content diet (0.4 %) (for 16 hours) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renal blood flow trait female 97.0 days-101.0 days 21 -1.4 ml/min/g 0.3 1.37 electromagnetic flowmetry 0.0 electromagnetic flowmetry change in renal blood flow rate 67305 151
SS/JrHsdMcwi ratio of change in renal blood flow rate to kidney weight controlled sodium content diet (0.4 %) (for 16 hours) then norepinephrine (3 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renal blood flow trait female 97.0 days-101.0 days 13 -2.4 ml/min/g 0.6 2.16 electromagnetic flowmetry 0.0 electromagnetic flowmetry 67308 151
BN/NHsdMcwi ratio of change in renal blood flow rate to kidney weight controlled sodium content diet (0.4 %) (for 16 hours) then NG-nitroarginine methyl ester (5 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renal blood flow trait female 97.0 days-101.0 days 20 -1.2 ml/min/g 0.7 3.13 electromagnetic flowmetry 0.0 electromagnetic flowmetry 67309 151
BN/NHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 110.0 mmHg 3.0 13.75 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11853 151
BN/NHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (for 21 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 89.0 days-92.0 days 20 serial mean 367.0 beats/min 5.0 22.36 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 13309 151
BN/NHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 92.0 days 14 1.4 ng/ml/h 0.4 1.5 ex vivo blood analysis enzyme assay 13308 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 139.1 mmHg 3.6 16.5 vascular indwelling catheter method left femoral artery 120.0 69533 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then acetylcholine (0.1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 9 serial mean 132.0 mmHg 7.0 21.0 vascular indwelling catheter method left femoral artery 120.0 69542 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 159.0 mmHg 6.4 23.08 vascular indwelling catheter method left femoral artery 120.0 69538 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) then acetylcholine (0.2 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 17 serial mean 144.9 mmHg 3.1 12.78 vascular indwelling catheter method left femoral artery 120.0 69549 151
BN/NHsdMcwi urine sodium level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 92.0 days-94.0 days 22 100.4 mmol/l 6.5 30.49 unspecified method 0.0 urine sodium analysis 69466 151
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 92.0 days-94.0 days 22 0.46 mEq/d 0.03 0.13 unspecified method 0.0 urine sodium analysis umol/min 69468 151
BN/NHsdMcwi urine potassium level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine potassium amount female 92.0 days-94.0 days 22 93.4 mmol/l 5.7 26.74 unspecified method 0.0 urine potassium analysis 69471 151
SS/JrHsdMcwi hematocrit controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. erythrocyte quantity female 89.0 days-92.0 days 15 38.8 % 1.4 5.42 hematocrit analysis 0.0 69482 151
SS/JrHsdMcwi plasma creatinine level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood creatinine amount female 92.0 days-94.0 days 11 1.05 mg/dl 0.23 0.76 plasma creatinine analysis 0.0 urine potassium analysis umol/min 69486 151
BN/NHsdMcwi left kidney wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney mass female 97.0 days-101.0 days 27 0.86 g 0.03 0.16 post excision weight measurement 0.0 69505 151
SS/JrHsdMcwi left kidney wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney mass female 97.0 days-101.0 days 20 1.27 g 0.07 0.31 post excision weight measurement 0.0 69506 151
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days 20 serial mean 140.6 mmHg 4.4 19.68 vascular indwelling catheter method left femoral artery 10800.0 69509 151
BN/NHsdMcwi right kidney wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney mass female 97.0 days-101.0 days 27 0.76 g 0.02 0.1 post excision weight measurement 0.0 69507 151
BN/NHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 93.0 days 20 serial mean 369.9 beats/min 5.1 22.81 vascular indwelling catheter method left femoral artery 10800.0 69519 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 15 serial mean 184.0 mmHg 7.7 29.82 vascular indwelling catheter method left femoral artery 0.0 69444 151
BN/NHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 89.0 days-91.0 days 18 serial mean 386.0 beats/min 4.1 17.39 vascular indwelling catheter method left femoral artery 0.0 69449 151
SS/JrHsdMcwi urine sodium level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 89.0 days-92.0 days 17 338.0 mmol/l 29.2 120.39 unspecified method 0.0 urine sodium analysis 69454 151
SS/JrHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 17 31.2 mg/dl 2.74 11.3 urine creatinine analysis 0.0 69456 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 12 serial mean 142.0 mmHg 5.0 17.32 vascular indwelling catheter method left femoral artery 0 65467 151
BN/NHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 93.0 days 14 serial mean 395.0 beats/min 7.0 26.19 vascular indwelling catheter method left femoral artery 0 65468 151
SS/JrHsdMcwi urine total protein excretion rate controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. total urine protein amount female 90.0 days-94.0 days 17 78.6 mg/d 9.0 37.11 urine total protein analysis 0 66152 151
SS/JrHsdMcwi absolute change in mean arterial blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) then tactile electric shock exposure (2 %) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 8 serial mean 11.0 mmHg 3.0 8.49 vascular indwelling catheter method left femoral artery 0 66150 151
BN/NHsdMcwi creatinine clearance controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. glomerular filtration trait female 90.0 days-94.0 days 10 1.7 ml/min 0.2 0.63 urine creatinine analysis 0.0 plasma creatinine analysis 67283 151
BN/NHsdMcwi single kidney wet weight to body weight ratio controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney mass female 97.0 days-101.0 days 26 5.0 g/kg 0.2 1.02 post excision weight measurement 0.0 67287 151
SS/JrHsdMcwi single kidney wet weight to body weight ratio controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney mass female 97.0 days-101.0 days 19 6.0 g/kg 0.4 1.74 post excision weight measurement 0.0 plasma creatinine analysis 67288 151
BN/NHsdMcwi plasma total cholesterol level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood cholesterol amount female 92.0 days-94.0 days 10 56.0 mg/dl 2.1 6.64 plasma total cholesterol measurement test 0.0 67289 151
BN/NHsdMcwi heart left ventricle wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart left ventricle mass female 97.0 days-101.0 days 22 0.45 g 0.01 0.05 post excision weight measurement 0.0 67297 151
SS/JrHsdMcwi heart left ventricle wet weight controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart left ventricle mass female 97.0 days-101.0 days 11 0.66 g 0.04 0.13 post excision weight measurement 0.0 plasma creatinine analysis 67298 151
SS/JrHsdMcwi ratio of change in renal blood flow rate to kidney weight controlled sodium content diet (0.4 %) (for 16 hours) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renal blood flow trait female 97.0 days-101.0 days 13 -2.4 ml/min/g 0.5 1.8 electromagnetic flowmetry 0.0 electromagnetic flowmetry 67306 151
BN/NHsdMcwi absolute change in mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 19 serial mean 22.0 mmHg 3.0 13.08 vascular indwelling catheter method left femoral artery 0.0 67301 151
SS/JrHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 154.0 mmHg 6.0 27.5 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11852 151
SS/JrHsdMcwi plasma renin activity level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renin activity female 92.0 days 7 2.2 ng/ml/h 0.58 1.53 ex vivo blood analysis 0.0 enzyme assay 13307 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (20 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 131.3 mmHg 4.2 15.14 vascular indwelling catheter method left femoral artery 120.0 69530 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (3 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 168.4 mmHg 7.0 25.24 vascular indwelling catheter method left femoral artery 120.0 69540 151
SS/JrHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 17 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 ug/min 69463 151
BN/NHsdMcwi timed urine volume controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine output female 92.0 days-94.0 days 25 9.86 ml/d 0.4 2.0 urine volume measurement method 0.0 needs ml/d default 69464 151
SS/JrHsdMcwi timed urine volume controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine output female 92.0 days-94.0 days 15 7.8 ml/d 0.6 2.32 urine volume measurement method 0.0 needs ml/d default 69465 151
SS/JrHsdMcwi urine potassium excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine potassium amount female 89.0 days-92.0 days 17 1.02 mEq/d 0.07 0.3 unspecified method 0.0 urine potassium analysis umol/min 69470 151
SS/JrHsdMcwi plasma total protein level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood total protein amount female 89.0 days-92.0 days 13 40.4 mg/ml 3.1 11.18 unspecified method 0.0 69484 151
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood creatinine amount female 92.0 days-94.0 days 8 0.42 mg/dl 0.11 0.31 plasma creatinine analysis 0.0 urine potassium analysis umol/min 69485 151
BN/NHsdMcwi white blood cell count controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. leukocyte quantity female 92.0 days-94.0 days 13 0.02 x 1000 cells/ul 1306.0 4708.85 isolated cell counting method 0.0 69495 151
BN/NHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 92.0 days 21 serial mean 386.5 beats/min 9.6 43.99 vascular indwelling catheter method left femoral artery 10800.0 69513 151
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 94.0 days 17 serial mean 134.6 mmHg 4.1 16.9 vascular indwelling catheter method left femoral artery 10800.0 69521 151
SS/JrHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 94.0 days 11 serial mean 140.0 mmHg 7.0 23.22 vascular indwelling catheter method left femoral artery 10800.0 69524 151
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 20 serial mean 130.0 mmHg 3.5 15.65 vascular indwelling catheter method left femoral artery 0.0 69443 151
BN/NHsdMcwi body weight controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) and controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. body mass female 84.0 days 33 167.0 g 3.4 19.53 body weighing method 0.0 69441 151
SS/JrHsdMcwi mean arterial blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 15 serial mean 159.0 mmHg 6.0 23.24 vascular indwelling catheter method left femoral artery 0.0 69448 151
SS/JrHsdMcwi timed urine volume controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine output female 89.0 days-92.0 days 17 30.0 ml/d 2.2 9.07 urine volume measurement method 0.0 69452 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 89.0 days-91.0 days 15 serial mean 442.0 beats/min 6.5 25.17 vascular indwelling catheter method left femoral artery 0.0 69450 151
SS/JrHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 89.0 days-92.0 days 17 5.06 mEq/d 0.6 2.49 unspecified method 0.0 urine sodium analysis umol/min 69460 151
BN/NHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 14 serial mean 110.0 mmHg 3.0 11.22 vascular indwelling catheter method left femoral artery 0 65462 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days-94.0 days 12 serial mean 160.0 mmHg 6.0 20.78 vascular indwelling catheter method left femoral artery 0 65463 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-92.0 days 21 serial mean 197.0 mmHg 7.0 32.08 vascular indwelling catheter method left femoral artery 3 hrs (during inactive phase) 3 consecutive days, and 4 extra hrs (during active phase) next day 11850 151
BN/NHsdMcwi plasma creatinine level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood creatinine amount female 90.0 days-94.0 days 11 0.4 mg/dl 0.06 0.2 plasma creatinine analysis 0.0 plasma creatinine analysis 66153 151
BN/NHsdMcwi kidney glomerulus diameter controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney glomerulus size trait female 97.0 days-101.0 days 22 95.0 um 1.2 5.63 ex vivo light microscopy 0.0 plasma creatinine analysis 67285 151
SS/JrHsdMcwi kidney glomerulus diameter controlled sodium content diet (0.4 %) (for 35 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. kidney glomerulus size trait female 97.0 days-101.0 days 16 117.0 um 3.8 15.2 ex vivo light microscopy 0.0 plasma creatinine analysis glomerular diameter 67286 151
SS/JrHsdMcwi plasma triglyceride level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. blood triglyceride amount female 92.0 days-94.0 days 11 1.4 mmol/l 0.21 0.71 plasma triglyceride analysis 0.0 67292 151
BN/NHsdMcwi absolute change in mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (200 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 20 serial mean 27.0 mmHg 2.0 8.94 vascular indwelling catheter method left femoral artery 0.0 67299 151
SS/JrHsdMcwi ratio of change in renal blood flow rate to kidney weight controlled sodium content diet (0.4 %) (for 16 hours) then NG-nitroarginine methyl ester (5 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renal blood flow trait female 97.0 days-101.0 days 9 1.9 ml/min/g 0.5 1.5 electromagnetic flowmetry 0.0 electromagnetic flowmetry 67310 151
BN/NHsdMcwi ratio of change in renal blood flow rate to kidney weight controlled sodium content diet (0.4 %) (for 16 hours) then norepinephrine (3 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. renal blood flow trait female 97.0 days-101.0 days 19 -1.4 ml/min/g 0.2 0.87 electromagnetic flowmetry 0.0 electromagnetic flowmetry 67307 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 126.0 mmHg 4.1 14.78 vascular indwelling catheter method left femoral artery 120.0 69528 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then angiotensin II (20 ng/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 20 serial mean 118.9 mmHg 4.4 19.68 vascular indwelling catheter method left femoral artery 120.0 69529 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then norepinephrine (0.5 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 13 serial mean 141.7 mmHg 7.4 26.68 vascular indwelling catheter method left femoral artery 120.0 69536 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then acetylcholine (0.1 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 111.3 mmHg 4.6 21.08 vascular indwelling catheter method left femoral artery 120.0 69541 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then acetylcholine (0.2 ug/kg/min) (for 0.1 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 9 serial mean 134.7 mmHg 7.4 22.2 vascular indwelling catheter method left femoral artery 120.0 69544 151
BN/NHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 21 serial mean 137.4 mmHg 4.0 18.33 vascular indwelling catheter method left femoral artery 120.0 69545 151
SS/JrHsdMcwi mean arterial blood pressure furosemide (10 mg/kg) then controlled sodium content diet (0.4 %) (for 7 days) then NG-nitroarginine methyl ester (5 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 101.0 days-103.0 days 9 serial mean 159.0 mmHg 7.1 21.3 vascular indwelling catheter method left femoral artery 120.0 69546 151
BN/NHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 23 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 ug/min 69462 151
SS/JrHsdMcwi urine potassium level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine potassium amount female 92.0 days-94.0 days 14 124.4 mmol/l 8.8 32.93 unspecified method 0.0 urine potassium analysis 69472 151
SS/JrHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 17 111.7 mg/dl 10.5 43.29 urine creatinine analysis 0.0 69476 151
SS/JrHsdMcwi urine creatinine excretion rate controlled sodium content diet (0.4 %) (for 16 hours) and furosemide (10 mg/kg) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 92.0 days-94.0 days 16 0.0 mg/d 0.0 0.0 urine creatinine analysis 0.0 mg/min 69478 151
BN/NHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days 20 serial mean 103.2 mmHg 2.8 12.52 vascular indwelling catheter method left femoral artery 10800.0 69511 151
SS/JrHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 92.0 days 16 serial mean 163.0 mmHg 6.4 25.6 vascular indwelling catheter method left femoral artery 10800.0 69512 151
SS/JrHsdMcwi systolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 93.0 days 11 serial mean 183.0 mmHg 10.0 33.17 vascular indwelling catheter method left femoral artery 10800.0 69516 151
BN/NHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 94.0 days 16 serial mean 370.1 beats/min 6.3 25.2 vascular indwelling catheter method left femoral artery 10800.0 69525 151
SS/JrHsdMcwi heart rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. heart pumping trait female 94.0 days 10 serial mean 411.7 beats/min 10.6 33.52 vascular indwelling catheter method left femoral artery 10800.0 69526 151
BN/NHsdMcwi diastolic blood pressure controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) then controlled exposure to darkness (for 12 hours) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. arterial blood pressure trait female 89.0 days-91.0 days 20 serial mean 96.0 mmHg 2.7 12.07 vascular indwelling catheter method left femoral artery 0.0 69445 151
BN/NHsdMcwi urine creatinine level controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine creatinine amount female 89.0 days-92.0 days 24 30.2 mg/dl 3.87 18.96 urine creatinine analysis 0.0 69455 151
BN/NHsdMcwi urine sodium excretion rate controlled sodium content diet (0.4 %) (for 35 days) then controlled sodium content diet (0.1 %) (for 35 days) then controlled sodium content diet (8 %) (between 22 and 24 days) Moreno C, et al., Physiol Genomics 2003 Nov 11;15(3):243-57. urine sodium amount female 89.0 days-92.0 days 24 6.35 mEq/d 0.35 1.74 unspecified method 0.0 urine sodium analysis umol/min 69459 151